Origin and biology of the allogeneic response

Cold Spring Harbor Perspectives in Medicine

Volumn 3, Issue 8, 2013, Pages

  Lakkis, Fadi G ^a   Lechler, Robert I ^b  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; HISTOCOMPATIBILITY ANTIGEN;

ANIMAL; ANTIGEN PRESENTATION; ARTICLE; GRAFT REJECTION; HUMAN; IMMUNOLOGY; IMMUNOSUPPRESSIVE TREATMENT; INNATE IMMUNITY; MAMMAL; METHODOLOGY; T LYMPHOCYTE;

ANIMALS; ANTIGEN PRESENTATION; GRAFT REJECTION; HISTOCOMPATIBILITY ANTIGENS; HUMANS; IMMUNITY, INNATE; IMMUNOSUPPRESSION; ISOANTIGENS; MAMMALS; T-LYMPHOCYTES;

EID: 84881083933     PISSN: None     EISSN: 21571422     Source Type: Journal    
DOI: 10.1101/cshperspect.a014993     Document Type: Article

References (71)

1. Auchincloss H Jr, Sultan H. 1996. Antigen processing and presentation in transplantation. Curr Opin Immunol 8: 681-687.
2. Auchincloss H, Lee R, Shea S, Markowitz JS, Grusby MJ, Glimcher LH. 1993. The role of "indirect" recognition in initiating rejection of skin grafts from major histocom-patibility complex class II-deficient mice. Proc Natl Acad Sci 90: 3373-3377.
3. Benham AM, Sawyer GJ, Fabre JW. 1995. Indirect T cell allorecognition of donor antigens contributes to the rejection of vascularized kidney allografts. Transplantation 59: 1028-1032.
4. Beutler BA. 2009. TLRs and innate immunity. Blood 113: 1399-1407.
5. Bowen KM, Andrus L, Lafferty KJ. 1980. Successful allo-transplantation of mouse pancreatic islets to nonimmu-nosuppressed recipients. Diabetes 29 (1): 98-104.
6. Burnet FM. 1971. "Self-recognition" in colonial marine forms and flowering plants in relation to the evolution of immunity. Nature 232: 230-235.
7. Buss L. 1982. Somatic cell parasitism and the evolution of somatic tissue compatibility. Proc Natl Acad Sci 79: 5337-5341.
8. Chalasani G, Dai Z, Konieczny BT, Baddoura FK, Lakkis FG. 2002. Recall and propagation of allospecific memory T cells independent of secondary lymphoid organs. Proc Natl Acad Sci 99: 6175-6180.
9. + T cells to differentiate into CTL retaining an early activation phe-notype. J Immunol 164: 5146-5155.
10. De Tomaso AW, Nyholm SV, Palmeri KJ, Ishizuka KJ, Lu-dington WB, Mitchel K, Weissman IL. 2005. Isolation and characterization of a protochordate histocompatibility locus. Nature 438: 454-459.
11. Dierselhuis M, Goulmy E. 2009. The relevance of minor histocompatibility antigens in solid organ transplantation. Curr Opin Organ Transplant 14: 419-425.
12. Dishaw LJ, Litman GW. 2009. Invertebrate allorecognition: The origins of histocompatibility. Curr Biol 19: R286-R288.
13. Divito SJ, Wang Z, Shufesky WJ, Liu Q, Tkacheva OA, Mon-tecalvo A, Erdos G, Larregina AT, Morelli AE. 2010. Endogenous dendritic cells mediate the effects of intravenously injected therapeutic immunosuppressive dendritic cells in transplantation. Blood 116: 2694-2705.
14. Ford ML, Larsen CP. 2010. Overcoming the memory barrier in tolerance induction: Molecular mimicryand functional heterogeneity among pathogen-specific T-cell populations. Curr Opin Organ Transplant 15: 405-410.
15. Garrod KR, Wei SH, Parker I, Cahalan MD. 2007. Natural killer cells actively patrol peripheral lymph nodes forming stable conjugatesto eliminate MHC-mismatched targets. Proc Natl Acad Sci 104: 12081-12086.
16. Garrod KR, Liu F-C, Forrest LE, Parker I, Kang S-M, Caha-lan MD. 2010. NK cell patrolling and elimination of donor-derived dendritic cells favor indirect alloreactivity. J Immunol 184: 2329-2336.
17. Hall BM, Dorsch S, Roser B. 1978a. The cellular basis of allograft rejection in vivo. I. The cellular requirements for first-set rejection of heart grafts. J Exp Med 148: 878-889.
18. Hall BM, Dorsch S, Roser B. 1978b. The cellular basis of allograft rejection in vivo. II. The nature of memory cells mediating second set heart graft rejection. J Exp Med 148: 890-902.
19. Herrera OB, Golshayan D, Tibbott R, Salcido Ochoa F, James MJ, Marelli-Berg FM, Lechler RI. 2004. A novel pathway of alloantigen presentation by dendritic cells. J Immunol 173: 4828-4837.
20. Hildemann WH. 1974. Some new concepts in immunolog-ical phylogeny. Nature 250: 116-129.
21. Janeway CA Jr. 1989. Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb Symp Quant Biol 54 (1): 1-13.
22. Janeway CJ. 2001. How the immune system works to protect the host from infection. Proc Natl Acad Sci 98: 7461-7468.
23. Kaplan B, Burkhart GJ, Lakkis FG, eds. 2012. Immunother-apy in transplantation: Principles and practice, p. 13. Wiley, New York.
24. + T cells and trigger acute rejection: An alternative mechanism of allorecognition. Nat Med 8: 233-239.
25. Lafferty KJ, Bootes A, Dart G, Talmage DW. 1976. Effect of organ culture onthe survivalofthyroid allografts inmice. Transplantation 22: 138-149.
26. Laird D, De Tomaso A, Weissman I. 2005. Stem cells are unit of natural selection inacolonial ascidian. Cell 123: 1351-1360.
27. Lakkis FG, Arakelov A, Konieczny BT, Inoue Y. 2000. Im-munologic "ignorance"of vascularized organ transplants in the absence of secondary lymphoid tissue. Nat Med 6: 686-688.
28. Larsen CP, Morris PJ, Austyn JM. 1990. Migration of dendritic leukocytes from cardiac allografts into host spleens: A novel pathway for initiation of rejection.JExp Med 171: 307-314.
29. Larsen CP, Steinman RM, Witmer-Pack M, Hankins DF, Morris PJ, Austyn JM. 1990. Migration and maturation of Langerhans cells in skin transplants and explants. J Exp Med 172: 1483-1493.
30. Lechler RI, Batchelor JR. 1982. Immunogenicityof retrans-planted rat kidney allografts. Effect of inducing chime-rism in the first recipient and quantitative studies on immunosuppression of the second recipient. J Exp Med 156: 1835-1841.
31. Lechler RI, Batchelor JR. 1982. Restoration of immunoge-nicity to passenger cell-depleted kidney allografts by the addition of donor strain dendritic cells. J Exp Med 155: 31-41.
32. Liu W, Xiao X, Demirci G, Madsen J, Li XC. 2012. Innate NK cells and macrophages recognize and reject allogeneic nonself in vivo via different mechanisms. J Immunol 188: 2703-2711.
33. Lombardi G, Sidhu S, Daly M, Batchelor JR, Makgoba W, Lechler RI. 1990. Are primary alloresponses truly primary? Int Immunol 2: 9-13.
34. + T cell immunity. Nat Rev Immunol 10: 236-247.
35. Macdonald WA, Chen Z, Gras S, Archbold JK, Tynan FE, Clements CS, Bharadwaj M, Kjer-Nielsen L, Saunders PM, Wilce MC, et al. 2009. T cell allorecognition via molecular mimicry. Immunity 31: 897-908.
36. Macedo C, Orkis EA, Popescu I, Elinoff BD, Zeevi A, Shapiro R, Lakkis FG, Metes D. 2009. Contribution of näi{dotless}ve and memory T-cell populations to the human alloim-mune response. Am J Transplant 9: 2057-2066.
37. + T-lymphocyte transendothelial migration (diapedesis) in vivo. Blood 103: 3111-3116.
38. McKitrick TR, Muscat CC, Pierce JD, Bhattacharya D, De Tomaso AW. 2011. Allorecognition in a basal chordate consists of independent activating and inhibitory pathways. Immunity 34: 616-626.
39. Merkenschlager M, Terry L, Edwards R, Beverley PC. 1988. Limiting dilution analysis of proliferative responses in human lymphocyte populations defined by the monoclonal antibody UCHL1: Implications for differential CD45 expression in T cell memory formation. Eur J Immunol 18: 1653-1661.
40. Miller JFAP. 1962. Effect of neonatal thymectomy on the immunological responsiveness of the mouse. Proc R Soc Lond B 156: 415-428.
41. Mokady O, Buss LW. 1996. Transmission genetics of allor-ecognition in Hydractinia symbiolongicarpus (Cnidaria: Hydrozoa). Genetics 143: 823-827.
42. Montecalvo A, Shufesky WJ, Stolz DB, Sullivan MG, Wang Z, Divito SJ, Papworth GD, Watkins SC, Robbins PD, Larregina AT, et al. 2008. Exosomes as a short-range mechanism to spread alloantigen between dendritic cells during T cell allorecognition. J Immunol 180: 3081-3090.
43. Ng YH, Oberbarnscheidt MH, Chandramoorthy HC, Hoffman R, Chalasani G. 2010. B cells help alloreactive T cells differentiate into memory T cells. Am J Transplant 10: 1970-1980.
44. Nicotra M, Powell A, Rosengarten R, Moreno M, Grimwood J, Lakkis F, Dellaporta S, Buss L. 2009. A hypervariable invertebrate allodeterminant. Curr Biol 19: 583-589.
45. Palm NW, Medzhitov R. 2009. Pattern recognition receptors and control of adaptive immunity. Immunol Rev 227: 221-233.
46. Peugh WN, Superina RA, Wood KJ, Morris PJ. 1986. The role of H-2 and non-H-2 antigens and genes in the rejection of murine cardiac allografts. Immunogenetics 23: 30-37.
47. Pober JS, Tellides G. 2012. Participation of blood vessel cells in human adaptive immune responses. Trends Immunol 33: 49-57.
48. Poudyal M, Rosa S, Powell AE, Moreno M, Dellaporta SL, Buss LW, Lakkis FG. 2007. Embryonic chimerism does not induce tolerance in an invertebrate model organism. Proc Natl Acad Sci 104: 4559-4564.
49. Rosa SF, Powell AE, Rosengarten RD, Nicotra ML, Moreno MA, Grimwood J, Lakkis FG, Dellaporta SL, Buss LW. 2010. Hydractinia allodeterminant alr1 resides in an im-munoglobulin superfamily-like gene complex. Curr Biol 20: 1122-1127.
50. Rosengarten RD, Nicotra ML. 2011. Model systems of invertebrate allorecognition. Curr Biol 21: R82-R92.
51. Safinia N, Afzali B, Atalar K, Lombardi G, Lechler RI. 2010. T-cell alloimmunity and chronic allograft dysfunction. Kidney Int Suppl 2010: S2-S12.
52. Sallusto F, Lanzavecchia A, Araki K, Ahmed R. 2010. From vaccines to memory and back. Immunity 33: 451-463.
53. Satpathy AT, Wu X, Albring JC, Murphy KM. 2012. Re(de)fining the dendritic cell lineage. Nat Immunol 13: 1145-1154.
54. Scott-Browne JP, Crawford F, Young MH, Kappler JW, Mar-rack P, Gapin L. 2011. Evolutionarily conserved features contribute to ab T cell receptor specificity. Immunity 35: 526-535.
55. Sheriff KA, Zeng Q, Li Q, Ng YH, Marlowe A, Randhawa P, Hoffman R, Chalasani G. 2011. B cells and not antibodies are required for T cell activation and development of chronic rejection. Am J Transplant 11: 40-41.
56. Sherman LA, Chattopadhyay S. 1993. The molecular basis of allorecognition. Annu Rev Immunol 11: 385-402.
57. + T cells directly recognize allogeneic endothelial cells in vitro and in vivo. J Immunol 179: 4397-4404.
58. Smyth LA, Afzali B, Tsang J, Lombardi G, Lechler RI. 2007. Intercellular transfer of MHC and immunological molecules: Molecular mechanisms and biological significance. Am J Transplant 7: 1442-1449.
59. Snell GD. 1957. The homograft reaction. Annu Rev Microbiol 11: 439-458.
60. Takemoto SK, Terasaki PI, Gjertson DW, Cecka JM. 2000. Twelve years' experience with national sharing of HLA-matched cadaveric kidneys for transplantation. N Engl J Med 343: 1078-1084.
61. Talmage DW, Dart G, Radovich J, Lafferty KJ. 1976. Activation of transplant immunity: Effect of donor leukocytes on thyroid allograft rejection. Science 191: 385-388.
62. Tydén G, Genberg H, Tollemar J, Ekberg H, Persson NH, Tufveson G, Wadstroöm J, Gäbel M, Mjörnstedt L. 2009. A randomized, doubleblind, placebo-controlled, study of single-dose rituximab as induction in renal transplantation. Transplantation 87: 1325-1329.
63. Valujskikh A, Matesic D, Gilliam A, Anthony D, Haqqi TM, Heeger PS. 1998. T cells reactive to a single immunodo-minant self-restricted allopeptide induce skin graft rejection in mice. J Clin Invest 101: 1398-1407.
64. + T cells mediate graft rejection via a distinct effector pathway. Nat Immunol 3: 844-851.
65. + T-cell activation after viral infection. Nature 471: 629-632.
66. + T cell migration to vascularized transplants. J Clin Invest 123: 2663-2671.
67. Yin Y, Mariuzza RA. 2009. The multiple mechanisms of T cell receptor cross-reactivity. Immunity 31: 849-851.
68. Yin L, Scott-Browne J, Kappler JW, Gapin L, Marrack P. 2012. T cells and their eons-old obsession with MHC. Immunol Rev 250: 49-60.
69. Zecher D, van Rooijen N, Rothstein D, Shlomchik W, Lakkis F. 2009. An innate response to allogeneic nonself mediated by monocytes. J Immunol 183: 7810-7816.
70. Zeng Q, Williams AL, Hoffman R, Rothstein DM, Ober-barnscheidt MH, Lakkis F. 2012. Innate recognition of allogeneic non-self induces monocyte differentiation to mature dendritic cells in vivo. Am J Transplant 12: 148- 148.
71. Zerrahn J, Held W, Raulet DH. 1997. The MHC reactivity of the T cell repertoire prior to positive and negative selection. Cell 88: 627-636.