Hyperoxia and interferon-γ-induced injury in developing lungs occur via cyclooxygenase-2 and the endoplasmic reticulum stress-dependent pathway

American Journal of Respiratory Cell and Molecular Biology

Volumn 48, Issue 6, 2013, Pages 749-757

  Choo Wing, Rayman ^a,e   Syed, Mansoor A ^a   Harijith, Anantha ^a,b,f   Bowen, Brianne ^a   Pryhuber, Gloria ^c   Janér, Cecilia ^d   Andersson, Sture ^d   Homer, Robert J ^a   Bhandari, Vineet ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Columbia University ^*  (United States)

^c UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^d UNIVERSITY OF HELSINKI   (Finland)

^e BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^f UNIVERSITY OF ILLINOIS   (United States)

Author keywords

BPD; Cell death; CHOP; Newborn; Oxygen

Indexed keywords

CASPASE 3; CELECOXIB; CYCLOOXYGENASE 2; GAMMA INTERFERON; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; SMALL INTERFERING RNA; CYCLOOXYGENASE 2 INHIBITOR; DDIT3 PROTEIN, MOUSE; PTGS2 PROTEIN, MOUSE; PYRAZOLE DERIVATIVE; SULFONAMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITION; GENE FUNCTION; HUMAN; HUMAN CELL; HYPEROXIA; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS EPITHELIUM; LUNG DEVELOPMENT; LUNG DYSPLASIA; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; CELL DEATH; DRUG EFFECT; GENETICS; LUNG; METABOLISM; NEWBORN; PATHOLOGY; PRENATAL DEVELOPMENT; TRANSGENIC MOUSE;

ANIMALS; ANIMALS, NEWBORN; BRONCHOPULMONARY DYSPLASIA; CELL DEATH; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; ENDOPLASMIC RETICULUM STRESS; HUMANS; HYPEROXIA; IMMUNOHISTOCHEMISTRY; INFANT, NEWBORN; INTERFERON-GAMMA; LUNG; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PYRAZOLES; RNA, SMALL INTERFERING; SULFONAMIDES; TRANSCRIPTION FACTOR CHOP;

MLCS; MLOWN;

EID: 84880997887     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2012-0381OC     Document Type: Article

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