Roundup disrupts male reproductive functions by triggering calcium-mediated cell death in rat testis and Sertoli cells

Free Radical Biology and Medicine

Volumn 65, Issue , 2013, Pages 335-346

  De Liz Oliveira Cavalli, Vera Lúcia ^a   Cattani, Daiane ^a   Heinz Rieg, Carla Elise ^a   Pierozan, Paula ^b   Zanatta, Leila ^a   Benedetti Parisotto, Eduardo ^a   Wilhelm Filho, Danilo ^a   Mena Barreto Silva, Fátima Regina ^a   Pessoa Pureur, Regina ^b   Zamoner, Ariane ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Calcium homeostasis; Cell death; Cell signaling; Free radicals; Glyphosate; Oxidative stress; Roundup; Sertoli cell

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; CALCIUM; CALCIUM CHANNEL L TYPE; CARBONYL DERIVATIVE; CATALASE; CYCLIC AMP DEPENDENT PROTEIN KINASE; GAMMA GLUTAMYLTRANSFERASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; GLYPHOSATE; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PESTICIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C; RYANODINE RECEPTOR; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TROLOX C; GLYCINE; HERBICIDE;

ACUTE TOXICITY; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; LIPID PEROXIDATION; MALE; MALE GENITAL SYSTEM; MOLECULAR MECHANICS; NONHUMAN; OXIDATIVE STRESS; PREPUBERTY; PRIORITY JOURNAL; RAT; SERTOLI CELL; SIGNAL TRANSDUCTION; SPERMATOGENESIS; TESTIS FUNCTION; ANALOGS AND DERIVATIVES; ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; METABOLISM; NECROSIS; PATHOLOGY; PHYSIOLOGY; TESTIS; WESTERN BLOTTING; WISTAR RAT;

RATTUS;

ANIMALS; BLOTTING, WESTERN; CALCIUM; GLYCINE; HERBICIDES; MALE; NECROSIS; OXIDATIVE STRESS; RATS; RATS, WISTAR; SERTOLI CELLS; TESTIS;

EID: 84880976847     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.06.043     Document Type: Article

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