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Volumn 516, Issue 2, 2012, Pages 226-231

Combination of p53(ser15) and p21/p21(thr145) in peripheral blood lymphocytes as potential Alzheimer's disease biomarkers

Author keywords

Alzheimer disease; Biomarkers; Cyclin dependent kinase inhibitor p21; Lymphocytes; Phosphorylation; Tumor suppressor protein p53

Indexed keywords

BIOLOGICAL MARKER; PROTEIN P21; PROTEIN P53;

EID: 84860494301     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2012.03.093     Document Type: Article
Times cited : (34)

References (25)
  • 2
    • 0141738373 scopus 로고    scopus 로고
    • CSF markers for incipient Alzheimer's disease
    • Blennow K., Hampel H. CSF markers for incipient Alzheimer's disease. Lancet Neurology 2003, 2:605-613.
    • (2003) Lancet Neurology , vol.2 , pp. 605-613
    • Blennow, K.1    Hampel, H.2
  • 3
    • 60549103891 scopus 로고    scopus 로고
    • Blood protein signature for the early diagnosis of Alzheimer disease
    • Britschgi M., Wyss-Coray T. Blood protein signature for the early diagnosis of Alzheimer disease. Archives of Neurology 2009, 66:161-165.
    • (2009) Archives of Neurology , vol.66 , pp. 161-165
    • Britschgi, M.1    Wyss-Coray, T.2
  • 5
    • 70349323831 scopus 로고    scopus 로고
    • A cognitive decline biomarker, can regulate translation via two consecutive molecular targets p53 and Redd1 in lymphocytes of AD patients
    • Damjanac M., Page G., Ragot S., Laborie G., Gil R., Hugon J., Paccalin M.P.K.R. a cognitive decline biomarker, can regulate translation via two consecutive molecular targets p53 and Redd1 in lymphocytes of AD patients. Journal of Cellular and Molecular Medicine 2009, 13:1823-1832.
    • (2009) Journal of Cellular and Molecular Medicine , vol.13 , pp. 1823-1832
    • Damjanac, M.1    Page, G.2    Ragot, S.3    Laborie, G.4    Gil, R.5    Hugon, J.6    Paccalin, M.P.K.R.7
  • 6
    • 0042594379 scopus 로고    scopus 로고
    • Ca2+/calmodulin-dependent modulation of cell cycle elements pRb and p27kip1 involved in the enhanced proliferation of lymphoblasts from patients with Alzheimer dementia
    • de las Cuevas N., Urcelay E., Hermida O.G., Saiz-Diaz R.A., Bermejo F., Ayuso M.S., Martin-Requero A. Ca2+/calmodulin-dependent modulation of cell cycle elements pRb and p27kip1 involved in the enhanced proliferation of lymphoblasts from patients with Alzheimer dementia. Neurobiology of Disease 2003, 13:254-263.
    • (2003) Neurobiology of Disease , vol.13 , pp. 254-263
    • de las Cuevas, N.1    Urcelay, E.2    Hermida, O.G.3    Saiz-Diaz, R.A.4    Bermejo, F.5    Ayuso, M.S.6    Martin-Requero, A.7
  • 7
    • 0141483381 scopus 로고    scopus 로고
    • Early intervention is key to successful management of Alzheimer disease
    • DeKosky S. Early intervention is key to successful management of Alzheimer disease. Alzheimer Disease and Associated Disorders 2003, 17(Suppl. 4):S99-S104.
    • (2003) Alzheimer Disease and Associated Disorders , vol.17 , Issue.SUPPL. 4
    • DeKosky, S.1
  • 8
    • 79960452243 scopus 로고    scopus 로고
    • Expression of 8-oxoguanine DNA glycosylase 1 (OGG1) and the level of p53 and TNF-alphalpha proteins in peripheral lymphocytes of patients with Alzheimer's disease, Folia neuropathologica/Association of Polish Neuropathologists and Medical Research Centre
    • Dezor M., Dorszewska J., Florczak J., Kempisty B., Jaroszewska-Kolecka J., Rozycka A., Polrolniczak A., Bugaj R., Jagodzinski P.P., Kozubski W. Expression of 8-oxoguanine DNA glycosylase 1 (OGG1) and the level of p53 and TNF-alphalpha proteins in peripheral lymphocytes of patients with Alzheimer's disease, Folia neuropathologica/Association of Polish Neuropathologists and Medical Research Centre. Polish Academy of Sciences 2011, 49:123-131.
    • (2011) Polish Academy of Sciences , vol.49 , pp. 123-131
    • Dezor, M.1    Dorszewska, J.2    Florczak, J.3    Kempisty, B.4    Jaroszewska-Kolecka, J.5    Rozycka, A.6    Polrolniczak, A.7    Bugaj, R.8    Jagodzinski, P.P.9    Kozubski, W.10
  • 9
    • 29244449016 scopus 로고    scopus 로고
    • Polymorphisms of the CHRNA4 gene encoding the alpha4 subunit of nicotinic acetylcholine receptor as related to the oxidative DNA damage and the level of apoptotic proteins in lymphocytes of the patients with Alzheimer's disease
    • Dorszewska J., Florczak J., Rozycka A., Jaroszewska-Kolecka J., Trzeciak W.H., Kozubski W. Polymorphisms of the CHRNA4 gene encoding the alpha4 subunit of nicotinic acetylcholine receptor as related to the oxidative DNA damage and the level of apoptotic proteins in lymphocytes of the patients with Alzheimer's disease. DNA and Cell Biology 2005, 24:786-794.
    • (2005) DNA and Cell Biology , vol.24 , pp. 786-794
    • Dorszewska, J.1    Florczak, J.2    Rozycka, A.3    Jaroszewska-Kolecka, J.4    Trzeciak, W.H.5    Kozubski, W.6
  • 10
    • 0034738420 scopus 로고    scopus 로고
    • P21(WAF1/Cip1): more than a break to the cell cycle?
    • Dotto G.P. p21(WAF1/Cip1): more than a break to the cell cycle?. Biochimica et biophysica acta 2000, 1471:M43-M56.
    • (2000) Biochimica et biophysica acta , vol.1471
    • Dotto, G.P.1
  • 12
    • 0347286635 scopus 로고    scopus 로고
    • Nerve growth factor restores p53 function in pituitary tumor cell lines via trkA-mediated activation of phosphatidylinositol 3-kinase
    • Facchetti M., Uberti D., Memo M., Missale C. Nerve growth factor restores p53 function in pituitary tumor cell lines via trkA-mediated activation of phosphatidylinositol 3-kinase. Molecular Endocrinology 2004, 18:162-172.
    • (2004) Molecular Endocrinology , vol.18 , pp. 162-172
    • Facchetti, M.1    Uberti, D.2    Memo, M.3    Missale, C.4
  • 13
    • 34147167052 scopus 로고    scopus 로고
    • Cell cycle checkpoints: the role and evaluation for early diagnosis of senescence, cardiovascular, cancer, and neurodegenerative diseases
    • Golubnitschaja O. Cell cycle checkpoints: the role and evaluation for early diagnosis of senescence, cardiovascular, cancer, and neurodegenerative diseases. Amino Acids 2007, 32:359-371.
    • (2007) Amino Acids , vol.32 , pp. 359-371
    • Golubnitschaja, O.1
  • 14
    • 77955963832 scopus 로고    scopus 로고
    • P53-Mediated neuronal cell death in ischemic brain injury
    • Hong L.Z., Zhao X.Y., Zhang H.L. p53-Mediated neuronal cell death in ischemic brain injury. Neuroscience Bulletin 2010, 26:232-240.
    • (2010) Neuroscience Bulletin , vol.26 , pp. 232-240
    • Hong, L.Z.1    Zhao, X.Y.2    Zhang, H.L.3
  • 17
    • 0030941458 scopus 로고    scopus 로고
    • P53, the cellular gatekeeper for growth and division
    • Levine A.J. p53, the cellular gatekeeper for growth and division. Cell 1997, 88:323-331.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 18
    • 0242551307 scopus 로고    scopus 로고
    • Cyclin-dependent kinases in neural development and degeneration
    • Lim A.C., Qi R.Z. Cyclin-dependent kinases in neural development and degeneration. Journal of Alzheimer's disease: JAD 2003, 5:329-335.
    • (2003) Journal of Alzheimer's disease: JAD , vol.5 , pp. 329-335
    • Lim, A.C.1    Qi, R.Z.2
  • 23
    • 0028352434 scopus 로고
    • The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
    • Waga S., Hannon G.J., Beach D., Stillman B. The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature 1994, 369:574-578.
    • (1994) Nature , vol.369 , pp. 574-578
    • Waga, S.1    Hannon, G.J.2    Beach, D.3    Stillman, B.4
  • 24
    • 37549015237 scopus 로고    scopus 로고
    • Panax ginseng ginsenoside-Rg2 protects memory impairment via anti-apoptosis in a rat model with vascular dementia
    • Zhang G., Liu A., Zhou Y., San X., Jin T., Jin Y. Panax ginseng ginsenoside-Rg2 protects memory impairment via anti-apoptosis in a rat model with vascular dementia. Journal of Ethnopharmacology 2008, 115:441-448.
    • (2008) Journal of Ethnopharmacology , vol.115 , pp. 441-448
    • Zhang, G.1    Liu, A.2    Zhou, Y.3    San, X.4    Jin, T.5    Jin, Y.6
  • 25
    • 72549104579 scopus 로고    scopus 로고
    • P53-mediated G(1)/S checkpoint dysfunction in lymphocytes from Alzheimer's disease patients
    • Zhou X., Jia J. P53-mediated G(1)/S checkpoint dysfunction in lymphocytes from Alzheimer's disease patients. Neuroscience Letters 2010, 468:320-325.
    • (2010) Neuroscience Letters , vol.468 , pp. 320-325
    • Zhou, X.1    Jia, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.