Interleukin-4, interleukin-4 receptor, and interleukin-18 polymorphisms and rheumatoid arthritis: A meta-analysis

Immunological Investigations

Volumn 42, Issue 6, 2013, Pages 455-469

  Song, Gwan Gyu ^a   Bae, Sang Cheol ^b   Kim, Jae Hoon ^a   Lee, Young Ho ^a  

^a Korea University College of Medicine   (South Korea)

^b Hanyang University Medical Center   (South Korea)

Author keywords

IL 18; Interleukin 4; Meta analysis; Polymorphism; Rheumatoid arthritis

Indexed keywords

INTERLEUKIN 18; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR;

ALLELE; ARTICLE; ASSOCIATION; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; DNA POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; META ANALYSIS; PRIORITY JOURNAL; RACE DIFFERENCE; RHEUMATOID ARTHRITIS;

ARTHRITIS, RHEUMATOID; ASIAN CONTINENTAL ANCESTRY GROUP; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTERLEUKIN-18; INTERLEUKIN-4; POLYMORPHISM, GENETIC; RECEPTORS, INTERLEUKIN-4;

EID: 84880895470     PISSN: 08820139     EISSN: 15324311     Source Type: Journal    
DOI: 10.3109/08820139.2013.804084     Document Type: Article

References (47)

1. Amerio P, Frezzolini A, Abeni D, et al. (2002). Increased IL-18 in patients with systemic lupus erythematosus: relations with Th-1, Th-2, pro-inflammatory cytokines and disease activity. IL-18 is a marker of disease activity but does not correlate with pro-inflammatory cytokines. Clin Exper Rheumatol, 20, 535-8. (Pubitemid 34846629)
2. Arman A, Coker A, Sarioz O, Inanc N, Direskeneli H. (2011). Lack of association between IL-6 gene polymorphisms and rheumatoid arthritis in Turkish population. Rheumatol Int, Jul 22, 2011 [Epub ahead of print] http://dx.doi.org/10.1007/s00296-011-2057-x.
3. Blankenstein T, Volk HD, Techert-Jendrusch C, et al. (1989). Lack of correlation between BglII RFLP in the human interleukin 6 gene and rheumatoid arthritis. Nucl Acids Res, 17, 8902. (Pubitemid 19273919)
4. Boraschi D, Dinarello CA. (2006). IL-18 in autoimmunity: review. Euro Cytokine Netw, 17, 224-52.
5. Cantagrel A, Navaux F, Loubet-Lescoulie P, et al. (1999). Interleukin-1beta, interleukin-1 receptor antagonist, interleukin-4, and interleukin-10 gene polymorphisms: relationship to occurrence and severity of rheumatoid arthritis. Arthritis Rheumatol, 42, 1093-1100. (Pubitemid 29268945)
6. Choi SJ, Rho YH, Ji JD, et al. (2006). Genome scan meta-analysis of rheumatoid arthritis. Rheumatology (Oxford), 45, 166-70. (Pubitemid 43160077)
7. Crilly A, Bartlett JM, White A, et al. (2001). Investigation of novel polymorphisms within the 3' region of the IL-6 gene in patients with rheumatoid arthritis using Genescan analysis. Cytokine, 13, 109-12. (Pubitemid 32579317)
8. Davey Smith G, Egger M. (1997). Meta-analyses of randomised controlled trials. Lancet, 350, 1182.
9. DerSimonian R, Laird N. (1986). Meta-analysis in clinical trials. Control Clin Trials, 7, 177-88. (Pubitemid 17189972)
10. Egger M, Davey Smith G, Schneider M, Minder C. (1997). Bias in meta-analysis detected by a simple, graphical test. BMJ, 315, 629-34. (Pubitemid 27387172)
11. Fishman D, Faulds G, Jeffery R, et al. (1998). The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J Clin Invest, 102, 1369-76. (Pubitemid 28467565)
12. Fugger L, Morling N, Bendtzen K, et al. (1989). IL-6 gene polymorphism in rheumatoid arthritis, pauciarticular juvenile rheumatoid arthritis, systemic lupus erythematosus, and in healthy Danes. J Immunogenet, 16, 461-5. (Pubitemid 20241512)
13. Genevay S, Di Giovine FS, Perneger TV, et al. (2002). Association of interleukin-4 and interleukin-1B gene variants with Larsen score progression in rheumatoid arthritis. Arthritis Rheum, 47, 303-9. (Pubitemid 34627699)
14. Giedraitis V, He B, Huang WX, Hillert J. (2001). Cloning and mutation analysis of the human IL-18 promoter: a possible role of polymorphisms in expression regulation. J Neuroimmunol, 112, 146-52.
15. Haus-Seuffert P, Meisterernst M. (2000). Mechanisms of transcriptional activation of cAMP-responsive element-binding protein CREB. Mol Cell Biochem, 212, 5-9.
16. Higgins JP, Thompson SG. (2002). Quantifying heterogeneity in a meta-analysis. Stat Med, 21, 1539-58. (Pubitemid 34746062)
17. Huang XZ, Zhuang JH, Ren YG, et al. (2007). [Association of interleukin-6 and interleukin-18 gene polymorphism with rheumatoid arthritis in Guangdong Han population]. Nan fang yi ke da xue xue bao=;J South Med Univ, 27, 1661-4.
18. Hussein Y, El-Tarhouny S, Mohamed R, et al. (2012). Association of interleukin-4 receptor gene polymorphisms with rheumatoid arthritis in Egyptian female patients. Joint, Bone, Spine: Revue du Rhumatisme 79, 38-42.
19. Lee YH, Rho YH, Choi SJ, et al. (2006). Association of TNF-alpha-308 G/A polymorphism with responsiveness to TNF-alpha-blockers in rheumatoid arthritis: a meta-analysis. Rheumatol Inter, 27, 157-61. (Pubitemid 46088273)
20. Lee YH, Witte T, Momot T, et al. (2005). The mannose-binding lectin gene polymorphisms and systemic lupus erythematosus: two case-control studies and a metaanalysis. Arthritis Rheum, 52, 3966-74. (Pubitemid 41798236)
21. Li Y, Guo B, Zhang L, et al. (2008). Association between C-589T polymorphisms of interleukin-4 gene promoter and asthma: a meta-analysis. Respir Med, 102, 984-92.
22. Li B, Tournier C, Davis RJ, Flavell RA. (1999). Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation. EMBO J, 18, 420-32. (Pubitemid 29041950)
23. Lo SF, Huang CM, Lin HC, et al. (2008). Cytokine (IL-6) and chemokine (IL-8) gene polymorphisms among rheumatoid arthritis patients in Taiwan. Clin Exper Rheumatol, 26, 632-7.
24. Lopez-Mejias R, Garcia-Bermudez M, Gonzalez-Juanatey C, et al. (2011). Lack of association between IL6 single nucleotide polymorphisms and cardiovascular disease in Spanish patients with rheumatoid arthritis. Atherosclerosis, 219, 655-8.
25. Marinou I, Till SH, Moore DJ, Wilson AG. (2008). Lack of association or interactions between the IL-4, IL-4Ralpha and IL-13 genes, and rheumatoid arthritis. Arthritis Res Ther, 10, 1-7.
26. Martinez A, Pascual M, Pascual-Salcedo D, et al. (2003). Genetic polymorphisms in Spanish rheumatoid arthritis patients: an association and linkage study. Genes Immun, 4, 117-21. (Pubitemid 38967585)
27. Mirel DB, Barcellos LF, Wang J, et al. (2004). Analysis of IL4R haplotypes in predisposition to multiple sclerosis. Genes Immun, 5, 138-41. (Pubitemid 38967643)
28. Moreno O, Gonzalez CI, Saaibi DL, et al. (2007). Polymorphisms in the IL4 and IL4RA genes in Colombian patients with rheumatoid arthritis. J Rheumatol, 34, 36-42. (Pubitemid 46106560)
29. Morita Y, Yamamura M, Kawashima M, et al. (2001). Differential in vitro effects of IL-4, IL-10, and IL-13 on proinflammatory cytokine production and fibroblast proliferation in rheumatoid synovium. Rheumatol Inter, 20, 49-54. (Pubitemid 33779812)
30. Nath SK, Harley JB, Lee YH. (2005). Polymorphisms of complement receptor 1 and interleukin-10 genes and systemic lupus erythematosus: a meta-analysis. Human Genetics, 118, 225-34. (Pubitemid 41672084)
31. Nelms K, Keegan AD, Zamorano J, et al. (1999). The IL-4 receptor: signaling mechanisms and biologic functions. Ann Rev Immunol, 17, 701-38. (Pubitemid 29241138)
32. Nolan KF, Greaves DR, Waldmann H. (1998). The human interleukin 18 gene IL18 maps to 11q22.2-q22.3, closely linked to the DRD2 gene locus and distinct from mapped IDDM loci. Genomics, 51, 161-3. (Pubitemid 28373391)
33. Nunez C, Santiago JL, Varade J, et al. (2008). IL4 in the 5q31 context: association studies of type 1 diabetes and rheumatoid arthritis in the Spanish population. Immunogenetics, 60, 19-23.
34. Palomino-Morales R, Gonzalez-Juanatey C, Vazquez-Rodriguez TR, et al. (2009). Interleukin-6 gene-174 promoter polymorphism is associated with endothelial dysfunction but not with disease susceptibility in patients with rheumatoid arthritis. Clin Exper Rheumatol, 27, 964-70.
35. Panoulas VF, Stavropoulos-Kalinoglou A, Metsios GS, et al. (2009). Association of interleukin-6 (IL-6)-174G/C gene polymorphism with cardiovascular disease in patients with rheumatoid arthritis: the role of obesity and smoking. Atherosclerosis, 204, 178-83.
36. Pawlik A, Kurzawski M, Czerny B, et al. (2006). Interleukin-18 promoter polymorphism in patients with rheumatoid arthritis. Tissue Antigens, 67, 415-8.
37. Pawlik A, Kurzawski M, Drozdzik M, et al. (2009). Interleukin-18 gene (IL18) promoter polymorphisms in patients with rheumatoid arthritis. Scand J Rheumatol, 38, 159-65.
38. Pawlik A, Wrzesniewska J, Florczak M, et al. (2005a). The-590 IL-4 promoter polymorphism in patients with rheumatoid arthritis. Rheumatol Inter, 26, 48-51. (Pubitemid 41531514)
39. Pawlik A, Wrzesniewska J, Florczak M, et al. (2005b). IL-6 promoter polymorphism in patients with rheumatoid arthritis. Scand J Rheumatol, 34, 109-13. (Pubitemid 40694829)
40. Prots I, Skapenko A, Wendler J, et al. (2006). Association of the IL4R single-nucleotide polymorphism I50V with rapidly erosive rheumatoid arthritis. Arthritis Rheum, 54, 1491-500.
41. Rosenwasser LJ, Klemm DJ, Dresback JK, et al. (1925). Promoter polymorphisms in the chromosome 5 gene cluster in asthma and atopy. Clin Exper Allergy: J Brit Soc Allergy Clin Immunol, 25 Suppl, 2, 74-8; discussion 95-6.
42. Rueda B, Gonzalez-Gay MA, Mataran L, et al. (2005). Interleukin-18- promoter polymorphisms are not relevant in rheumatoid arthritis. Tissue Antigens, 65, 544-8. (Pubitemid 40776303)
43. Sivalingam SP, Yoon KH, Koh DR, Fong KY. (2003). Single-nucleotide polymorphisms of the interleukin-18 gene promoter region in rheumatoid arthritis patients: protective effect of AA genotype. Tissue Antigens, 62, 498-504. (Pubitemid 37475997)
44. Sugiura T, Kawaguchi Y, Ikari K, et al. (2011). Interleukin-18 promoter polymorphisms in Japanese patients with rheumatoid arthritis: protective effect of the T allele and T/T genotype at rs360722. Mod Rheumatol/Japan Rheum Asso, 21, 359-64.
45. Suppiah V, Rooney M, Vandenbroeck K. (2006). Polymorphisms in the interleukin-4 and IL-4 receptor genes modify risk for chronic inflammatory arthropathies in women. Exper Mol Pathol, 81, 239-44. (Pubitemid 44665860)
46. Trajkov D, Mishevska-Perchinkova S, Karadzova-Stojanoska A, et al. (2009). Association of 22 cytokine gene polymorphisms with rheumatoid arthritis in population of ethnic Macedonians. Clin Rheumatol, 28, 1291-300.
47. Ying B, Shi Y, Pan X, et al. (2011). Association of polymorphisms in the human IL-10 and IL-18 genes with rheumatoid arthritis. Mol Biol Repts, 38, 379-85.