Association of interleukin-4 and interleukin-1B gene variants with Larsen score progression in rheumatoid arthritis

Arthritis Care and Research

Volumn 47, Issue 3, 2002, Pages 303-309

  Genevay, Stéphane ^a   Di Giovine, Francesco S ^b   Perneger, Thomas V ^a   Silvestri, Tania ^b   Stingelin, Sibylle ^a   Duff, Gordon ^b   Guerne, Pierre André ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Genetic polymorphism; Interleukin 1; Interleukin 4; Larsen score; Rheumatoid arthritis

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 4;

ADULT; AGED; ARTICLE; DISEASE COURSE; DISEASE SEVERITY; FEMALE; GENE CLUSTER; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; RADIOGRAPHY; RHEUMATIC POLYMYALGIA; RHEUMATOID ARTHRITIS; SCORING SYSTEM; TANDEM REPEAT;

EID: 0037097609     PISSN: 21514658     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.10394     Document Type: Article

References (41)

1. Limited heterogeneity of the HLA class II contribution to susceptibility to rheumatoid arthritis is suggested by positive associations with HLA-DR4, DR1 and DRw10
2. Correlation between disease phenotype and genetic heterogeneity in rheumatoid arthritis
3. Association of the B-cell alloantigen DRw4 with rheumatoid arthritis
4. HLA-DRB1 genotype influences risk for and severity of rheumatoid arthritis
5. The genetic contribution to the pathogenesis of rheumatoid arthritis
6. The Heberden Oration 1997: Treatment of rheumatoid arthritis: From symptomatic relief to potential cure
7. Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis
8. Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells
9. The biological properties of interleukin-1
10. Role of cytokines in rheumatoid arthritis
11. Role of interleukin 1 in antigen-induced exacerbations of murine arthritis
12. The effect of an interleukin-1 receptor antagonist protein on type II collagen-induced arthritis and antigen-induced arthritis in mice
13. Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist
14. Regulatory role of interleukin 10 in joint inflammation and cartilage destruction in murine streptococcal cell wall (SCW) arthritis. More therapeutic benefit with IL-4/IL-10 combination therapy than with IL-10 treatment alone
15. Inhibition of the production of proinflammatory cytokines and immunoglobulins by interleukin-4 in an ex vivo model of rheumatoid synovitis
16. Th1/Th2 cytokine balance in arthritis
17. Detection and population analysis of IL-1 and TNF gene polymorphisms
18. Combined sib-TDT and TDT provide evidence for linkage of the interleukin-1 gene cluster to erosive rheumatoid arthritis
19. A genetic association between juvenile rheumatoid arthritis and a novel interleukin-1α polymorphism
20. Interleukin-1 receptor antagonist gene polymorphism as a disease severity factor in systemic lupus erythematosus
21. Novel genetic association between ulcerative colitis and the anti-inflammatory cytokine interleukin-1 receptor antagonist
22. Repeat polymorphisms in the interleukin-4 gene (IL4)
23. Occurrence and clinical relevance of an interleukin-4 gene polymorphism in patients with multiple sclerosis
24. The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor
25. Molecular analysis of HLA-DR polymorphism in polymyalgia rheumatica
26. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
27. Radiographic evaluation of rheumatoid arthritis and related conditions by standard reference films
28. Detection of specific polymerase chain reaction product by utilizing the 5′ - 3′ exonuclease activity of Thermus aquaticus DNA polymerase
29. Robust locally weighted regression and smoothing scatterplots
30. The effect of glucocorticoids on joint destruction in rheumatoid arthritis
31. A trial of etanercept, a recombinant tumor necrosis factor receptor: Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate
32. Treatment of active rheumatoid arthritis with leflunomide compared with placebo and methotrexate
33. Conventional monotherapy compared to a "sawtooth" treatment strategy in the radiographic progression of rheumatoid arthritis over the first eight years
34. Association of rheumatoid factors and antifilaggrin antibodies with severity of erosions in rheumatoid arthritis
35. Radiographic progression in rheumatoid arthritis: A long-term prospective study of 109 patients
36. Five novel intragenic dimorphisms in the human interleukin-1 genes combine to high informativity
37. Interleukin-1 polymorphisms associated with increased risk of gastric cancer
38. Investigation of an interleukin-4 promoter polymorphism for associations with asthma and atopy
39. Promoter polymorphisms in the chromosome 5 gene cluster in asthma and atopy
40. Interleukin-1β, interleukin-1 receptor antagonist, interleukin-4, and interleukin-10 gene polymorphisms: Relationship to occurrence and severity of rheumatoid arthritis
41. IL-4 VNTR gene polymorphism in chronic polyarthritis: The rare allele is associated with protection against destruction