The -590 IL-4 promoter polymorphism in patients with rheumatoid arthritis

Rheumatology International

Volumn 26, Issue 1, 2005, Pages 48-51

  Pawlik, Andrzej ^a   Wrzesniewska, Joanna ^a   Florczak, Marcin ^a   Gawronska Szklarz, Barbara ^a   Herczynska, Magdalena ^a  

^a POMERANIAN MEDICAL UNIVERSITY   (Poland)

Author keywords

IL 4; Polymorphism; Rheumatoid arthritis

Indexed keywords

INTERLEUKIN 4;

ADULT; AGED; ALLELE; ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE SEVERITY; DNA POLYMORPHISM; FEMALE; GENE AMPLIFICATION; GENETIC ANALYSIS; GENETIC RISK; GENOTYPE; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN LOCALIZATION; RHEUMATOID ARTHRITIS; RISK FACTOR;

ADULT; AGED; ALLELES; ARTHRITIS, RHEUMATOID; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HETEROZYGOTE; HUMANS; INTERLEUKIN-4; MALE; MIDDLE AGED; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; SEVERITY OF ILLNESS INDEX;

EID: 27444446016     PISSN: 01728172     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00296-004-0539-9     Document Type: Article

References (19)

1. John S, Myerscough A, Marlow A, Hajeer A, Silman A, Ollier W, Worthington J (1998) Linkage of cytokine genes to rheumatoid arthritis. Evidence of genetic heterogeneity. Ann Rheum Dis 57:361-365
2. Ared WP, Dayer JM (1990) Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis. Arth Rheum 33:305-315
3. Li B, Tournier C, Davis RJ, Flavell RA (1999) Regulation of Il-4 expression by the transcription factor JunB during T helper cell differentiation. EMBO J 18:420-432
4. Wenner CA, Szabo SJ, Murphy KM (1997) Identification of IL-4 promoter elements conferring Th2-restricted expression during T helper cell subset development. J Immunol 158:765-773
5. Castro A, Sengupta TK, Ruiz DC, Yang E, Ivashkiv LB (1999) IL-4 selectively inhibits IL-2-triggered Stat5 activation, but not proliferation, in human T cells. J Immunol 162:1261-1269
6. Vannier E, Miller LC, Dinarello CA (1992) Coordinated anti-inflammatory effects of interleukin 4: interleukin 4 suppresses interleukin 1 production but up-regulates gene expression and synthesis of interleukin 1 receptor antagonist. Proc Natl Acad Sci USA 89:4076-4080
7. Rosenwasser LJ, Klemm DJ, Dresback JK, Inamura H, Mascali JJ, Klinnert M, Borish L (1995) Promoter polymorphisms in the chromosome 5 gene cluster in asthma and atopy. Clin Exp Allergy 25:74-78
8. Song Z, Casolaro V, Chen R, Georas SN, Monos D, Ono SJ (1996) Polymorphic nucleotides within the human IL-4 promoter that mediate overexpression of the gene. J Immunol 156:1131-1136
9. Mout R, Willemze R, Landegent JE (1991) Repeat polymorphisms in the interleukin-4 gene. Nucleic Acid Res 19:3763
10. Cantagrel A, Navaux F, Loubet-Lescoulie P, Nourhashemi F, Enault G, Abbal M, Constantin A, Laroche M, Mazieres B (1999) Interleukin-1beta, interleukin-1 receptor antagonist, interleukin-4, and interleukin-10 gene polymorphisms: relationship to occurrence and severity of rheumatoid arthritis. Arthr Rheum 42:1093-1100
11. Genevay S, Di Giovine FS, Perneger TV, Silvestri T, Stingelin S, Duff G, Guerne PA (2002) Association of interleukin-4 and interleukin-1B gene variants with Larsen score progression in rheumatoid arthritis. Arthr Rheum 47:303-309
12. Prevoo ML, van 't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL (1995) Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthr Rheum 38:44-48
13. Felson DT, Anderson JJ, Boers M, Bombardier C, Chernoff M, Fried B, Furst D, Goldsmith C, Kieszak S, Lightfoot R (1993) The American College of Rheumatology preliminary core set of disease activity measures for rheumatoid arthritis clinical trials. The committee on outcome measures in Rheumatoid Arthritis Clinical Trials. Arthr Rheum 36:729-740
14. Kanemitsu S, Takabayashi A, Sasaki Y, Kuromaru R, Ihara K, Kaku Y, Sakai K, Hara T (1999) Association of interleukin-4 receptor and interleukin-4 promoter gene polymorphisms with systemic lupus erythematosus. Arthr Rheum 42:1298-1300
15. Maksymowych WP, Suarez-Almazor ME, Buenviaje H, Cooper BL, Degeus C, Thompson M, Russell AS (2002) HLA and cytokine gene polymorphisms in relation to occurrence of palindromic rheumatism and its progression to rheumatoid arthritis. J Rheumatol 29:2319-2326
16. Noguchi E, Shibasaki M, Arinami T, Takeda K, Yokouchi Y, Kawashima T, Yanagi H, Matsui A, Hamaguchi H (1998) Association of asthma and the interleukin-4 promoter gene in Japanese. Clin Exp Allergy 28:449-453
17. Li-Weber M, Laur O, Davydov IV, Hu C, Salgame P, Krammer PH (1997) What controls tissue-specific expression of the Il-4 gene? Immunobiology 198:170-178
18. Cantrell D (1996) T cell antigen receptor signal transduction pathways. Annu Rev Immunol 14:259-274
19. Kawashima T, Noguchi E, Arinami T, Yamakawa-Kobayashi K, Nakagawa H, Otsuka F, Hamaguchi H (1998) Linkage and association of an interleukin 4 gene polymorphism with atopic dermatitis in Japanese families. J Med Genet 35:502-504