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Volumn 1, Issue 5, 2012, Pages 642-648

Tumor antigen specific iTreg accumulate in the tumor microenvironment and suppress therapeutic vaccination

Author keywords

FoxP3; iTreg; nTreg; Regulatory T cell; Tumor microenvironment

Indexed keywords

B7 ANTIGEN; CD86 ANTIGEN; GLYCOPROTEIN P 15095; T LYMPHOCYTE RECEPTOR; TUMOR ANTIGEN;

EID: 84880887899     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.4161/onci.20298     Document Type: Article
Times cited : (31)

References (36)
  • 1
    • 77955066199 scopus 로고    scopus 로고
    • IMPACT Study Investigators Sipuleucel-T immunotherapy for castration-resistant prostate cancer
    • PMID:20818862
    • Kantoff PW, Higano CS, Shore ND, Berger ER, Small EJ, Penson DF, et al.; IMPACT Study Investigators. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med 2010; 363:411-22; PMID:20818862; http://dx.doi.org/10.1056/ NEJMoa1001294.
    • (2010) N Engl J Med , vol.363 , pp. 411-422
    • Kantoff, P.W.1    Higano, C.S.2    Shore, N.D.3    Berger, E.R.4    Small, E.J.5    Penson, D.F.6
  • 2
    • 79959772576 scopus 로고    scopus 로고
    • Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
    • PMID:21639810
    • Robert C, Thomas L, Bondarenko I, O'Day S, Jeffrey Weber, Garbe C, et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med 2011; 364:2517-26; PMID:21639810; http:// dx.doi.org/10.1056/NEJMoa1104621.
    • (2011) N Engl J Med , vol.364 , pp. 2517-2526
    • Robert, C.1    Thomas, L.2    Bondarenko, I.3    O'Day, S.4    Weber, J.5    Garbe, C.6
  • 3
    • 84862776855 scopus 로고    scopus 로고
    • Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
    • PMID:22318521
    • Matsushita H, Vesely MD, Koboldt DC, Rickert CG, Uppaluri R, Magrini VJ, et al. Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting. Nature 2012; 482:400-4; PMID:22318521; http://dx.doi.org/10.1038/nature10755.
    • (2012) Nature , vol.482 , pp. 400-404
    • Matsushita, H.1    Vesely, M.D.2    Koboldt, D.C.3    Rickert, C.G.4    Uppaluri, R.5    Magrini, V.J.6
  • 4
    • 84857118418 scopus 로고    scopus 로고
    • Expression of tumour-specific antigens underlies cancer immunoediting
    • PMID:22318517
    • DuPage M, Mazumdar C, Schmidt LM, Cheung AF, Jacks T. Expression of tumour-specific antigens underlies cancer immunoediting. Nature 2012; 482:405-9; PMID:22318517; http://dx.doi.org/10.1038/ nature10803.
    • (2012) Nature , vol.482 , pp. 405-409
    • DuPage, M.1    Mazumdar, C.2    Schmidt, L.M.3    Cheung, A.F.4    Jacks, T.5
  • 5
    • 79953059789 scopus 로고    scopus 로고
    • Natural innate and adaptive immunity to cancer
    • PMID:21219185
    • Vesely MD, Kershaw MH, Schreiber RD, Smyth MJ. Natural innate and adaptive immunity to cancer. Annu Rev Immunol 2011; 29:235-71; PMID:21219185; http://dx.doi.org/10.1146/annurevimmunol- 031210-101324.
    • (2011) Annu Rev Immunol , vol.29 , pp. 235-271
    • Vesely, M.D.1    Kershaw, M.H.2    Schreiber, R.D.3    Smyth, M.J.4
  • 6
    • 43949105866 scopus 로고    scopus 로고
    • Regulatory T cells and immune tolerance
    • PMID:18510923
    • Sakaguchi S, Yamaguchi T, Nomura T, Ono M. Regulatory T cells and immune tolerance. Cell 2008; 133:775-87; PMID:18510923; http://dx.doi. org/10.1016/j.cell.2008.05.009.
    • (2008) Cell , vol.133 , pp. 775-787
    • Sakaguchi, S.1    Yamaguchi, T.2    Nomura, T.3    Ono, M.4
  • 7
    • 0141591497 scopus 로고    scopus 로고
    • + T cells responding to serologically defined autoantigens suppress antitumor immune responses
    • PMID:12947044
    • + T cells responding to serologically defined autoantigens suppress antitumor immune responses. Proc Natl Acad Sci USA 2003; 100:10902-6; PMID:12947044; http://dx.doi. org/10.1073/pnas.1834479100.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10902-10906
    • Nishikawa, H.1    Kato, T.2    Tanida, K.3    Hiasa, A.4    Tawara, I.5    Ikeda, H.6
  • 8
    • 20144381908 scopus 로고    scopus 로고
    • Definition of target antigens for naturally occurring CD4(+) CD25(+) regulatory T cells
    • PMID:15753203
    • Nishikawa H, Kato T, Tawara I, Saito K, Ikeda H, Kuribayashi K, et al. Definition of target antigens for naturally occurring CD4(+) CD25(+) regulatory T cells. J Exp Med 2005; 201:681-6; PMID:15753203; http://dx.doi.org/10.1084/jem.20041959.
    • (2005) J Exp Med , vol.201 , pp. 681-686
    • Nishikawa, H.1    Kato, T.2    Tawara, I.3    Saito, K.4    Ikeda, H.5    Kuribayashi, K.6
  • 9
    • 79551521901 scopus 로고    scopus 로고
    • Analysis of the T-cell receptor repertoires of tumor-infiltrating conventional and regulatory T cells reveals no evidence for conversion in carcinogen- induced tumors
    • PMID:21156649
    • Hindley JP, Ferreira C, Jones E, Lauder SN, Ladell K, Wynn KK, et al. Analysis of the T-cell receptor repertoires of tumor-infiltrating conventional and regulatory T cells reveals no evidence for conversion in carcinogen- induced tumors. Cancer Res 2011; 71:736-46; PMID:21156649; http://dx.doi.org/10.1158/0008-5472.CAN-10-1797.
    • (2011) Cancer Res , vol.71 , pp. 736-746
    • Hindley, J.P.1    Ferreira, C.2    Jones, E.3    Lauder, S.N.4    Ladell, K.5    Wynn, K.K.6
  • 10
    • 30444443314 scopus 로고    scopus 로고
    • Amplification of tumor-specific regulatory T cells following therapeutic cancer vaccines
    • PMID:16179369
    • Zhou G, Drake CG, Levitsky HI. Amplification of tumor-specific regulatory T cells following therapeutic cancer vaccines. Blood 2006; 107:628-36; PMID:16179369; http://dx.doi.org/10.1182/blood- 2005-07-2737.
    • (2006) Blood , vol.107 , pp. 628-636
    • Zhou, G.1    Drake, C.G.2    Levitsky, H.I.3
  • 11
    • 33846913897 scopus 로고    scopus 로고
    • Natural regulatory T cells and de novo-induced regulatory T cells contribute independently to tumor-specific tolerance
    • PMID:17277120
    • Zhou G, Levitsky HI. Natural regulatory T cells and de novo-induced regulatory T cells contribute independently to tumor-specific tolerance. J Immunol 2007; 178:2155-62; PMID:17277120.
    • (2007) J Immunol , vol.178 , pp. 2155-2162
    • Zhou, G.1    Levitsky, H.I.2
  • 12
    • 84876176361 scopus 로고    scopus 로고
    • Induced CD4(+)Foxp3(+) Regulatory T Cells in Immune Tolerance
    • PMID:22224762
    • Bilate AM, Lafaille JJ. Induced CD4(+)Foxp3(+) Regulatory T Cells in Immune Tolerance. Annu Rev Immunol 2011; PMID:22224762.
    • (2011) Annu Rev Immunol
    • Bilate, A.M.1    Lafaille, J.J.2
  • 13
    • 73949118500 scopus 로고    scopus 로고
    • CD4(+) CD25(+) Foxp3(+) T regulatory cells with limited TCR diversity in control of autoimmunity
    • PMID:19949075
    • Adeegbe D, Matsutani T, Yang J, Altman NH, Malek TR. CD4(+) CD25(+) Foxp3(+) T regulatory cells with limited TCR diversity in control of autoimmunity. J Immunol 2010; 184:56-66; PMID:19949075; http:// dx.doi.org/10.4049/jimmunol.0902379.
    • (2010) J Immunol , vol.184 , pp. 56-66
    • Adeegbe, D.1    Matsutani, T.2    Yang, J.3    Altman, N.H.4    Malek, T.R.5
  • 14
    • 0027251463 scopus 로고
    • The sizes of the CDR3 hypervariable regions of the murine T-cell receptor beta chains vary as a function of the recombined germ-line segments
    • PMID:8483950
    • Pannetier C, Cochet M, Darche S, Casrouge A, Zöller M, Kourilsky P. The sizes of the CDR3 hypervariable regions of the murine T-cell receptor beta chains vary as a function of the recombined germ-line segments. Proc Natl Acad Sci USA 1993; 90:4319-23; PMID:8483950; http://dx.doi.org/10.1073/ pnas.90.9.4319.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 4319-4323
    • Pannetier, C.1    Cochet, M.2    Darche, S.3    Casrouge, A.4    Zöller, M.5    Kourilsky, P.6
  • 16
    • 77950541195 scopus 로고    scopus 로고
    • Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cells
    • PMID:19706884
    • Robins HS, Campregher PV, Srivastava SK, Wacher A, Turtle CJ, Kahsai O, et al. Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cells. Blood 2009; 114:4099-107; PMID:19706884; http://dx.doi.org/10.1182/blood-2009-04-217604.
    • (2009) Blood , vol.114 , pp. 4099-4107
    • Robins, H.S.1    Campregher, P.V.2    Srivastava, S.K.3    Wacher, A.4    Turtle, C.J.5    Kahsai, O.6
  • 17
    • 58849112222 scopus 로고    scopus 로고
    • Cutting edge: antigen-specific TGFbetainduced regulatory T cells suppress Th17-mediated autoimmune disease
    • PMID:19050237
    • Huter EN, Stummvoll GH, DiPaolo RJ, Glass DD, Shevach EM. Cutting edge: antigen-specific TGFbetainduced regulatory T cells suppress Th17-mediated autoimmune disease. J Immunol 2008; 181:8209-13; PMID:19050237.
    • (2008) J Immunol , vol.181 , pp. 8209-8213
    • Huter, E.N.1    Stummvoll, G.H.2    DiPaolo, R.J.3    Glass, D.D.4    Shevach, E.M.5
  • 18
    • 48249143387 scopus 로고    scopus 로고
    • + regulatory T lymphocytes through the induction of anergy and infectious tolerance
    • PMID:18292504
    • + regulatory T lymphocytes through the induction of anergy and infectious tolerance. J Immunol 2008; 180:2830-8; PMID:18292504.
    • (2008) J Immunol , vol.180 , pp. 2830-2838
    • Selvaraj, R.K.1    Geiger, T.L.2
  • 19
    • 77953633327 scopus 로고    scopus 로고
    • TGFbeta-induced myelin peptide-specific regulatory T cells mediate antigen-specific suppression of induction of experimental autoimmune encephalomyelitis
    • PMID:20483764
    • Zhang H, Podojil JR, Chang J, Luo X, Miller SD. TGFbeta-induced myelin peptide-specific regulatory T cells mediate antigen-specific suppression of induction of experimental autoimmune encephalomyelitis. J Immunol 2010; 184:6629-36; PMID:20483764; http://dx.doi.org/10.4049/jimmunol.0904044.
    • (2010) J Immunol , vol.184 , pp. 6629-6636
    • Zhang, H.1    Podojil, J.R.2    Chang, J.3    Luo, X.4    Miller, S.D.5
  • 21
    • 40749084404 scopus 로고    scopus 로고
    • Suppression of mature dendritic cell function by regulatory T cells in vivo is abrogated by CD40 licensing
    • PMID:18209035
    • Hänig J, Lutz MB. Suppression of mature dendritic cell function by regulatory T cells in vivo is abrogated by CD40 licensing. J Immunol 2008; 180:1405-13; PMID:18209035.
    • (2008) J Immunol , vol.180 , pp. 1405-1413
    • Hänig, J.1    Lutz, M.B.2
  • 23
    • 79960453738 scopus 로고    scopus 로고
    • A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity
    • PMID:21723159
    • Haribhai D, Williams JB, Jia S, Nickerson D, Schmitt EG, Edwards B, et al. A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity. Immunity 2011; 35:109-22; PMID:21723159; http://dx.doi.org/10.1016/j. immuni.2011.03.029.
    • (2011) Immunity , vol.35 , pp. 109-122
    • Haribhai, D.1    Williams, J.B.2    Jia, S.3    Nickerson, D.4    Schmitt, E.G.5    Edwards, B.6
  • 25
    • 80053168628 scopus 로고    scopus 로고
    • Polyclonal Treg cells modulate T effector cell trafficking
    • PMID:21728170
    • Davidson TS, Shevach EM. Polyclonal Treg cells modulate T effector cell trafficking. Eur J Immunol 2011; 41:2862-70; PMID:21728170; http://dx.doi. org/10.1002/eji.201141503.
    • (2011) Eur J Immunol , vol.41 , pp. 2862-2870
    • Davidson, T.S.1    Shevach, E.M.2
  • 27
    • 49649095420 scopus 로고    scopus 로고
    • Polyclonal adaptive regulatory CD4 cells that can reverse type I diabetes become oligoclonal long-term protective memory cells
    • PMID:18641317
    • Godebu E, Summers-Torres D, Lin MM, Baaten BJ, Bradley LM. Polyclonal adaptive regulatory CD4 cells that can reverse type I diabetes become oligoclonal long-term protective memory cells. J Immunol 2008; 181:1798-805; PMID:18641317.
    • (2008) J Immunol , vol.181 , pp. 1798-1805
    • Godebu, E.1    Summers-Torres, D.2    Lin, M.M.3    Baaten, B.J.4    Bradley, L.M.5
  • 28
    • 84862777225 scopus 로고    scopus 로고
    • Extrathymically generated regulatory T cells control mucosal TH2 inflammation
    • PMID:22318520
    • Josefowicz SZ, Niec RE, Kim HY, Treuting P, Chinen T, Zheng Y, et al. Extrathymically generated regulatory T cells control mucosal TH2 inflammation. Nature 2012; 482:395-9; PMID:22318520; http://dx.doi. org/10.1038/nature10772.
    • (2012) Nature , vol.482 , pp. 395-399
    • Josefowicz, S.Z.1    Niec, R.E.2    Kim, H.Y.3    Treuting, P.4    Chinen, T.5    Zheng, Y.6
  • 29
    • 51049108540 scopus 로고    scopus 로고
    • Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma
    • PMID:18725522
    • Quezada SA, Peggs KS, Simpson TR, Shen Y, Littman DR, Allison JP. Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma. J Exp Med 2008; 205:2125-38; PMID:18725522; http://dx.doi.org/10.1084/jem.20080099.
    • (2008) J Exp Med , vol.205 , pp. 2125-2138
    • Quezada, S.A.1    Peggs, K.S.2    Simpson, T.R.3    Shen, Y.4    Littman, D.R.5    Allison, J.P.6
  • 30
    • 65549136983 scopus 로고    scopus 로고
    • + T regulatory cell-mediated suppression
    • PMID:19464986
    • + T regulatory cell-mediated suppression. Immunity 2009; 30:636-45; PMID:19464986; http://dx.doi.org/10.1016/j. immuni.2009.04.010.
    • (2009) Immunity , vol.30 , pp. 636-645
    • Shevach, E.M.1
  • 31
    • 17044430217 scopus 로고    scopus 로고
    • Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter
    • PMID:15795373
    • Wan YY, Flavell RA. Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter. Proc Natl Acad Sci USA 2005; 102:5126-31; PMID:15795373; http://dx.doi.org/10.1073/pnas.0501701102.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 5126-5131
    • Wan, Y.Y.1    Flavell, R.A.2
  • 32
    • 15244354286 scopus 로고    scopus 로고
    • Regulatory T cell lineage specification by the forkhead transcription factor foxp3
    • PMID:15780990
    • Fontenot JD, Rasmussen JP, Williams LM, Dooley JL, Farr AG, Rudensky AY. Regulatory T cell lineage specification by the forkhead transcription factor foxp3. Immunity 2005; 22:329-41; PMID:15780990; http:// dx.doi.org/10.1016/j.immuni.2005.01.016.
    • (2005) Immunity , vol.22 , pp. 329-341
    • Fontenot, J.D.1    Rasmussen, J.P.2    Williams, L.M.3    Dooley, J.L.4    Farr, A.G.5    Rudensky, A.Y.6
  • 34
    • 0032560475 scopus 로고    scopus 로고
    • Demonstration of an interferongamma- dependent tumor surveillance system in immunocompetent mice
    • PMID:9636188
    • Kaplan DH, Shankaran V, Dighe AS, Stockert E, Aguet M, Old LJ, et al. Demonstration of an interferongamma- dependent tumor surveillance system in immunocompetent mice. Proc Natl Acad Sci USA 1998; 95:7556-61; PMID:9636188; http://dx.doi. org/10.1073/pnas.95.13.7556.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 7556-7561
    • Kaplan, D.H.1    Shankaran, V.2    Dighe, A.S.3    Stockert, E.4    Aguet, M.5    Old, L.J.6
  • 35
    • 43549110073 scopus 로고    scopus 로고
    • Essential role of TNF receptor superfamily 25 (TNFRSF25) in the development of allergic lung inflammation
    • PMID:18411341
    • Fang L, Adkins B, Deyev V, Podack ER. Essential role of TNF receptor superfamily 25 (TNFRSF25) in the development of allergic lung inflammation. J Exp Med 2008; 205:1037-48; PMID:18411341; http://dx.doi. org/10.1084/jem.20072528.
    • (2008) J Exp Med , vol.205 , pp. 1037-1048
    • Fang, L.1    Adkins, B.2    Deyev, V.3    Podack, E.R.4
  • 36
    • 33846186870 scopus 로고    scopus 로고
    • Comparison of CDR3 length among thymocyte subpopulations: impacts of MHC and BV segment on the CDR3 shortening
    • PMID:17156844
    • Matsutani T, Ohmori T, Ogata M, Soga H, Kasahara S, Yoshioka T, et al. Comparison of CDR3 length among thymocyte subpopulations: impacts of MHC and BV segment on the CDR3 shortening. Mol Immunol 2007; 44:2378-87; PMID:17156844; http://dx.doi. org/10.1016/j.molimm.2006.10.026.
    • (2007) Mol Immunol , vol.44 , pp. 2378-2387
    • Matsutani, T.1    Ohmori, T.2    Ogata, M.3    Soga, H.4    Kasahara, S.5    Yoshioka, T.6


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