Cyclic enkephalins with a diversely substituted guanidine bridge or a thiourea bridge: Synthesis, biological and structural evaluations

Journal of Medicinal Chemistry

Volumn 56, Issue 14, 2013, Pages 5964-5973

  Touati Jallabe, Youness ^a   Bojnik, Engin ^b   Legrand, Baptiste ^c   Mauchauffée, Elodie ^a   Chung, Nga N ^d   Schiller, Peter W ^d,e   Benyhe, Sandor ^b   Averlant Petit, Marie Christine ^c   Martinez, Jean ^a   Hernandez, Jean François ^a  

^a UNIVERSITÉ DE MONTPELLIER   (France)

^b INSTITUTE OF BIOCHEMISTRY   (Hungary)

^c UNIVERSITÉ DE LORRAINE   (France)

^d CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^e UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DELTA OPIATE RECEPTOR; ENKEPHALIN; GUANIDINE; GUANINE NUCLEOTIDE BINDING PROTEIN; MU OPIATE RECEPTOR; OPIATE; THIOUREA;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CHROMATOGRAPHY; DRUG STRUCTURE; DRUG SYNTHESIS; ILEUM; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; VAS DEFERENS;

ANIMALS; ENKEPHALINS; GUANIDINE; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDES, CYCLIC; RATS; RECEPTORS, OPIOID, MU; STRUCTURE-ACTIVITY RELATIONSHIP; THIOUREA;

EID: 84880887509     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm4008592     Document Type: Article

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