메뉴 건너뛰기




Volumn 66, Issue 5, 2005, Pages 255-262

Design of high affinity cyclic pentapeptide ligands for κ-opioid receptors

Author keywords

opioid receptor; Cyclic peptides; G protein coupled receptor; Opioid ligands

Indexed keywords

CARBENE; DELTA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR; LIGAND; METHYLENE DITHIOETHER; MU OPIATE RECEPTOR; PENTAPEPTIDE; TYROSYLCYSTEINYLPHENYLALANYLPHENYLALANINAMIDE; UNCLASSIFIED DRUG;

EID: 27644545467     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3011.2005.00295.x     Document Type: Article
Times cited : (18)

References (23)
  • 2
    • 0027052952 scopus 로고
    • The delta opioid receptor: Isolation of a cDNA by expression cloning and pharmacological characterization
    • Kieffer, B.L., Befort, K., Gaveriaux-Ruff, C. & Hirth, C.G. (1992) The delta opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization. Proc. Natl Acad. Sci. U S A 89, 12048-12052.
    • (1992) Proc. Natl. Acad. Sci. U S A , vol.89 , pp. 12048-12052
    • Kieffer, B.L.1    Befort, K.2    Gaveriaux-Ruff, C.3    Hirth, C.G.4
  • 3
    • 0027503898 scopus 로고
    • Molecular cloning of a rat kappa opioid receptor reveals sequence similarities to the mu and delta opioid receptors
    • Chen, Y., Mestek, A., Liu, J. & Yu, L. (1993) Molecular cloning of a rat kappa opioid receptor reveals sequence similarities to the mu and delta opioid receptors. Biochem. J. 295, 625-628.
    • (1993) Biochem. J. , vol.295 , pp. 625-628
    • Chen, Y.1    Mestek, A.2    Liu, J.3    Yu, L.4
  • 5
    • 0027504836 scopus 로고
    • Cloning and pharmacological characterization of a rat mu opioid receptor
    • Thompson, R.C., Mansour, A., Akil, H. & Watson, S.J. (1993) Cloning and pharmacological characterization of a rat mu opioid receptor. Neuron 11, 903-913.
    • (1993) Neuron , vol.11 , pp. 903-913
    • Thompson, R.C.1    Mansour, A.2    Akil, H.3    Watson, S.J.4
  • 9
    • 0036945574 scopus 로고    scopus 로고
    • Development and validation of opioid ligand-receptor interaction models: The structural basis of mu vs. delta selectivity
    • Mosberg, H.I. & Fowler, C.B. (2002) Development and validation of opioid ligand-receptor interaction models: the structural basis of mu vs. delta selectivity. J. Pept. Res. 60, 329-335.
    • (2002) J. Pept. Res. , vol.60 , pp. 329-335
    • Mosberg, H.I.1    Fowler, C.B.2
  • 10
    • 10844246435 scopus 로고    scopus 로고
    • Complex of and active mu opioid receptor with cyclic peptide agonist modeled from experimental constraints
    • Fowler, C.B., Pogozheva, I.D., Lomize, A.L., LeVine, H. III & Mosberg, H.I. (2004) Complex of and active mu opioid receptor with cyclic peptide agonist modeled from experimental constraints. Biochemistry 43, 15796-15810.
    • (2004) Biochemistry , vol.43 , pp. 15796-15810
    • Fowler, C.B.1    Pogozheva, I.D.2    Lomize, A.L.3    LeVine III, H.4    Mosberg, H.I.5
  • 11
    • 0020334525 scopus 로고
    • 5]enkephalin sequences, extended at the C-terminus, with the mu-, delta- and kappa-binding sites in the guinea-pig brain
    • 5]enkephalin sequences, extended at the C-terminus, with the mu-, delta- and kappa-binding sites in the guinea-pig brain. Life Sci. 31, 1359-1361.
    • (1982) Life Sci. , vol.31 , pp. 1359-1361
    • Magnan, J.1    Paterson, S.J.2    Kosterlitz, H.W.3
  • 12
    • 0345158331 scopus 로고
    • Specific receptor for the opioid peptide dynorphin: Structure-activity relationships
    • Chavkin, C. & Goldstein, A. (1981) Specific receptor for the opioid peptide dynorphin: structure-activity relationships. Proc. Natl Acad. Sci. U S A 78, 6543-6547.
    • (1981) Proc. Natl. Acad. Sci. U S A , vol.78 , pp. 6543-6547
    • Chavkin, C.1    Goldstein, A.2
  • 13
    • 0026494942 scopus 로고
    • Effect of modification of the basic residues of dynorphin A-(1-13) amide on kappa opioid receptor selectivity and opioid activity
    • Snyder, K.R., Story, S.C., Heidt, M.E., Murray, T.F., DeLander, G.E. & Aldrich, J.V. (1992) Effect of modification of the basic residues of dynorphin A-(1-13) amide on kappa opioid receptor selectivity and opioid activity. J. Med. Chem. 35, 4330-4333.
    • (1992) J. Med. Chem. , vol.35 , pp. 4330-4333
    • Snyder, K.R.1    Story, S.C.2    Heidt, M.E.3    Murray, T.F.4    DeLander, G.E.5    Aldrich, J.V.6
  • 14
    • 0346962964 scopus 로고    scopus 로고
    • Synthesis and opioid activity of side-chain-to-side-chain cyclic dynorphin A-(1-11) amide analogs cyclized between positions 2 and 5: 1. Substitutions in position 3
    • Vig, B.S., Murray, T.F. & Aldrich, J.V. (2004) Synthesis and opioid activity of side-chain-to-side-chain cyclic dynorphin A-(1-11) amide analogs cyclized between positions 2 and 5: 1. Substitutions in position 3. J. Med. Chem. 47, 446-455.
    • (2004) J. Med. Chem. , vol.47 , pp. 446-455
    • Vig, B.S.1    Murray, T.F.2    Aldrich, J.V.3
  • 17
    • 0032791257 scopus 로고    scopus 로고
    • Novel binding properties of oripavines at a cloned mu opioid receptor
    • Lee, K., Aku, H., Woods, J.H. & Traynor, J.R. (1999) Novel binding properties of oripavines at a cloned mu opioid receptor. Eur. J. Pharmacol. 378, 323-330.
    • (1999) Eur. J. Pharmacol. , vol.378 , pp. 323-330
    • Lee, K.1    Aku, H.2    Woods, J.H.3    Traynor, J.R.4
  • 18
    • 0026089657 scopus 로고
    • Efficient computation of three-dimensional protein structure in solution from NMR data using the program DIANA and the supporting programs CALIBA, HABAS and GLOMSA
    • Güntert, P., Brawn, W. & Wüthrich, K. (1991) Efficient computation of three-dimensional protein structure in solution from NMR data using the program DIANA and the supporting programs CALIBA, HABAS and GLOMSA. J. Mol. Biol. 11, 517-530.
    • (1991) J. Mol. Biol. , vol.11 , pp. 517-530
    • Güntert, P.1    Brawn, W.2    Wüthrich, K.3
  • 21
    • 30644458763 scopus 로고    scopus 로고
    • Homology modeling of opioid receptor-ligand complexes using experimental constraints
    • in press
    • Pogozheva, I.D., Przydzial, M.J. & Mosberg, H.I. (2005) Homology modeling of opioid receptor-ligand complexes using experimental constraints. AAPS J. (in press).
    • (2005) AAPS J.
    • Pogozheva, I.D.1    Przydzial, M.J.2    Mosberg, H.I.3
  • 22
    • 0345665740 scopus 로고
    • Cyclic deltorphin analogs with high delta opioid receptor affinity and selectivity
    • Proceedings of the 13th American Peptide Symposium (Hodges, R.S. & Smith, J.A., eds). ESCOM, Leiden, the Netherlands
    • Mosberg, H.I., Kroona, H.B., Omnaas, J.R., Sobczyk-Kojiro, K., Bush, P. & Mousigian, C. (1994) Cyclic deltorphin analogs with high delta opioid receptor affinity and selectivity. In: Peptides: Chemistry, Structure and Biology. Proceedings of the 13th American Peptide Symposium (Hodges, R.S. & Smith, J.A., eds), pp. 514-516. ESCOM, Leiden, the Netherlands.
    • (1994) Peptides: Chemistry, Structure and Biology , pp. 514-516
    • Mosberg, H.I.1    Kroona, H.B.2    Omnaas, J.R.3    Sobczyk-Kojiro, K.4    Bush, P.5    Mousigian, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.