메뉴 건너뛰기




Volumn 96, Issue 6, 2006, Pages 830-838

Chronological expression of PAR isoforms in acute liver injury and its amelioration by PAR2 blockade in a rat model of sepsis

Author keywords

Coagulation; Endotoxin; Inflammation; Liver injury; Protease activated receptor (PAR)

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BLOOD CLOTTING FACTOR 7A; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; ISOPROTEIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEINASE ACTIVATED RECEPTOR; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 2; PROTEINASE ACTIVATED RECEPTOR 3; PROTEINASE ACTIVATED RECEPTOR 4; RECEPTOR BLOCKING AGENT; SC 9278P; THROMBIN; TISSUE FACTOR PATHWAY INHIBITOR; TUMOR NECROSIS FACTOR ALPHA;

EID: 33845358121     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH06-07-0379     Document Type: Article
Times cited : (15)

References (29)
  • 1
    • 0034927828 scopus 로고    scopus 로고
    • Hepatic response to sepsis: Interaction between coagulation and inflammatory processes
    • Dhainaut JF, Marin N, Mignon A, et al. Hepatic response to sepsis: interaction between coagulation and inflammatory processes. Crit Care Med 2001, 29 (Suppl): S42-S7.
    • (2001) Crit Care Med , vol.29 , Issue.SUPPL.
    • Dhainaut, J.F.1    Marin, N.2    Mignon, A.3
  • 3
    • 0036074141 scopus 로고    scopus 로고
    • Lipopolysaccharides in liver injury: Molecular mechanisms of Kupffer cell activation
    • Su GL. Lipopolysaccharides in liver injury: molecular mechanisms of Kupffer cell activation. Am J Physiol Gastrointest Liver Physiol 2002; 283: G256-G65.
    • (2002) Am J Physiol Gastrointest Liver Physiol , vol.283
    • Su, G.L.1
  • 4
    • 0028014478 scopus 로고
    • Endotoxin-induced cytokine gene expression and excretion in the liver
    • Luster MI, Germolec DR, Yoshida T, et al. Endotoxin-induced cytokine gene expression and excretion in the liver. Hepatology 1994; 19: 480-8.
    • (1994) Hepatology , vol.19 , pp. 480-488
    • Luster, M.I.1    Germolec, D.R.2    Yoshida, T.3
  • 5
    • 0027729864 scopus 로고
    • Relationship between tumor necrosis factor-α and neutrophils in endotoxin-induced liver injury
    • Hewett JA, Jean PA, Kunkel SL, et al. Relationship between tumor necrosis factor-α and neutrophils in endotoxin-induced liver injury. Am J Physiol Gastrointest Liver Physiol 1993; 265: G1011-G5.
    • (1993) Am J Physiol Gastrointest Liver Physiol , vol.265
    • Hewett, J.A.1    Jean, P.A.2    Kunkel, S.L.3
  • 6
    • 0027215179 scopus 로고
    • Potential role of hepatic macrophages in neutrophil-mediated liver injury in rats with sepsis
    • Doi F, Goya T, Torisu M. Potential role of hepatic macrophages in neutrophil-mediated liver injury in rats with sepsis. Hepatology 1993; 17: 1086-94.
    • (1993) Hepatology , vol.17 , pp. 1086-1094
    • Doi, F.1    Goya, T.2    Torisu, M.3
  • 7
    • 0023237728 scopus 로고
    • Sinusoidal circulatory disturbance by microthrombosis as a cause of endotoxin-induced hepatic injury
    • Shibayama Y. Sinusoidal circulatory disturbance by microthrombosis as a cause of endotoxin-induced hepatic injury. J Pathol 1987; 151: 315-21.
    • (1987) J Pathol , vol.151 , pp. 315-321
    • Shibayama, Y.1
  • 8
    • 0033965530 scopus 로고    scopus 로고
    • Neutrophils express tissue factor in a monkey model of sepsis
    • Todoroki H, Nakamura S, Higure A, et al. Neutrophils express tissue factor in a monkey model of sepsis. Surgery 2000; 127: 209-16.
    • (2000) Surgery , vol.127 , pp. 209-216
    • Todoroki, H.1    Nakamura, S.2    Higure, A.3
  • 9
    • 0032924316 scopus 로고    scopus 로고
    • Deranged blood coagulation equilibrium as factor of massive liver necrosis following endotoxin administration in partially bepatectomized rats
    • Mochida S, Arai M, Ohno A, et al. Deranged blood coagulation equilibrium as factor of massive liver necrosis following endotoxin administration in partially bepatectomized rats. Hepatology 1999; 29: 1532-40.
    • (1999) Hepatology , vol.29 , pp. 1532-1540
    • Mochida, S.1    Arai, M.2    Ohno, A.3
  • 10
    • 0025181049 scopus 로고
    • Endotoxin induction of plasminogen activator and plasminogen activator inhibitor type 1 mRNA in rat tissue in vivo
    • Quax PA, van den Hoogen CM, Verheijen JH, et al. Endotoxin induction of plasminogen activator and plasminogen activator inhibitor type 1 mRNA in rat tissue in vivo. J Biol Chem 1990; 26: 15560-3.
    • (1990) J Biol Chem , vol.26 , pp. 15560-15563
    • Quax, P.A.1    van den Hoogen, C.M.2    Verheijen, J.H.3
  • 11
    • 0031016324 scopus 로고    scopus 로고
    • Induction of plasminogen activator inhibitor 1 gene expression in marine liver by lipopolysaccharide. Cellular localization and role of endogenous tumor necrosis factor-α
    • Fearns C, Loskutoff DJ. Induction of plasminogen activator inhibitor 1 gene expression in marine liver by lipopolysaccharide. Cellular localization and role of endogenous tumor necrosis factor-α. Am J Pathol 1997; 150: 579-90.
    • (1997) Am J Pathol , vol.150 , pp. 579-590
    • Fearns, C.1    Loskutoff, D.J.2
  • 12
    • 0030795504 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha is involved in the induction of plasminogen activator inhibitor-1 by endotoxin
    • Yamashita M, Yamashita M. Tumor necrosis factor alpha is involved in the induction of plasminogen activator inhibitor-1 by endotoxin. Thromb Res 1997; 87: 165-70.
    • (1997) Thromb Res , vol.87 , pp. 165-170
    • Yamashita, M.1    Yamashita, M.2
  • 13
    • 0141609935 scopus 로고    scopus 로고
    • Inflammation and thrombosis
    • Esmon CT. Inflammation and thrombosis. J Thromb Haemost 2003; 1: 1343-8.
    • (2003) J Thromb Haemost , vol.1 , pp. 1343-1348
    • Esmon, C.T.1
  • 14
    • 0034648757 scopus 로고    scopus 로고
    • Thrombin signaling and protease-activated receptors
    • Coughlin SR. Thrombin signaling and protease-activated receptors. Nature 2000; 407: 258-64.
    • (2000) Nature , vol.407 , pp. 258-264
    • Coughlin, S.R.1
  • 15
    • 0036357526 scopus 로고    scopus 로고
    • Receptors of the PARs family as a link between blood coagulation and inflammation
    • Dugina TN, Kiseleva EV, Chistov IV, et al. Receptors of the PARs family as a link between blood coagulation and inflammation. Biochemistry (Moscow) 2002; 67: 65-74.
    • (2002) Biochemistry (Moscow) , vol.67 , pp. 65-74
    • Dugina, T.N.1    Kiseleva, E.V.2    Chistov, I.V.3
  • 16
    • 0034624973 scopus 로고    scopus 로고
    • Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa
    • Camerer E, Huang W, Coughlin SR. Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa. PNAS 2000; 97; 5255-60.
    • (2000) PNAS , vol.97 , pp. 5255-5260
    • Camerer, E.1    Huang, W.2    Coughlin, S.R.3
  • 17
    • 0036271051 scopus 로고    scopus 로고
    • Orchestration of coagulation protease signaling by tissue factor
    • Riewald M, Ruf W. Orchestration of coagulation protease signaling by tissue factor. Trend Cardiovascular Med 2002; 12: 149-54.
    • (2002) Trend Cardiovascular Med , vol.12 , pp. 149-154
    • Riewald, M.1    Ruf, W.2
  • 18
    • 0037405842 scopus 로고    scopus 로고
    • Thrombin and protease-activated receptor-1 agonists promote lipopolysaccharide-induced hepatocellular injury in perfused livers
    • Copple BL, Moulin F, Hanumegowda UM, et al. Thrombin and protease-activated receptor-1 agonists promote lipopolysaccharide-induced hepatocellular injury in perfused livers. J Pharmacol Exp Ther 2003; 305; 417-25.
    • (2003) J Pharmacol Exp Ther , vol.305 , pp. 417-425
    • Copple, B.L.1    Moulin, F.2    Hanumegowda, U.M.3
  • 19
    • 15844401726 scopus 로고    scopus 로고
    • The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells
    • Nystedt S, Ramakrishnan V, Sundelin J. The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells. J Biol Chem 1996; 271: 14910-5.
    • (1996) J Biol Chem , vol.271 , pp. 14910-14915
    • Nystedt, S.1    Ramakrishnan, V.2    Sundelin, J.3
  • 20
    • 0035816730 scopus 로고    scopus 로고
    • Increased expression of protease-activated receptor-2 (PAR2) and PAR4 in human coronary artery by inflammatory stimuli unveils endothelium-dependent relaxations to PAR2 and PAR4 agonists
    • Hamilton JR, Frauman AG, Cocks TM. Increased expression of protease-activated receptor-2 (PAR2) and PAR4 in human coronary artery by inflammatory stimuli unveils endothelium-dependent relaxations to PAR2 and PAR4 agonists. Circ Res 2001; 89: 92-8.
    • (2001) Circ Res , vol.89 , pp. 92-98
    • Hamilton, J.R.1    Frauman, A.G.2    Cocks, T.M.3
  • 21
    • 9144267034 scopus 로고    scopus 로고
    • Temporal changes in pulmonary expression of key coagulant molecules in rabbits with endotoxin-induced acute lung injury: Elevated expression levels of protease-activated receptors
    • Jesmin S, Gando S, Matsuda N, et al. Temporal changes in pulmonary expression of key coagulant molecules in rabbits with endotoxin-induced acute lung injury: elevated expression levels of protease-activated receptors. Thromb Haemost 2004; 92: 966-79.
    • (2004) Thromb Haemost , vol.92 , pp. 966-979
    • Jesmin, S.1    Gando, S.2    Matsuda, N.3
  • 22
    • 0346728613 scopus 로고    scopus 로고
    • Diminished penile expression of vascular endothelial growth factor and its receptors at the insulin-resistant stage of a type II diabetic rat model: A possible cause for erectile dysfunction in diabetes
    • Jesmin S, Sakuma I, Salah-Eldin A, et al. Diminished penile expression of vascular endothelial growth factor and its receptors at the insulin-resistant stage of a type II diabetic rat model: a possible cause for erectile dysfunction in diabetes. J Mol Endocrinol 2003; 31: 401-18.
    • (2003) J Mol Endocrinol , vol.31 , pp. 401-408
    • Jesmin, S.1    Sakuma, I.2    Salah-Eldin, A.3
  • 23
    • 0036671659 scopus 로고    scopus 로고
    • Effects of exercise training on expression of endothelin-1 mRNA in the aorta of aged rats
    • Maeda S, Miyauchi T, Iemitsu M, et al. Effects of exercise training on expression of endothelin-1 mRNA in the aorta of aged rats. Clin Sci (Lond) 2002; Suppl 48: 118S-23S.
    • (2002) Clin Sci (Lond) , vol.48 , Issue.SUPPL.
    • Maeda, S.1    Miyauchi, T.2    Iemitsu, M.3
  • 25
    • 0030435119 scopus 로고    scopus 로고
    • The thrombin inhibitor, hirudin, attenuates lipopolysaccharide-induced liver injury in the rat
    • Pearson JM, Schultze AE, Schwartz KA, et al. The thrombin inhibitor, hirudin, attenuates lipopolysaccharide-induced liver injury in the rat. J Pharmacol Exp Ther 1996; 278: 378-83.
    • (1996) J Pharmacol Exp Ther , vol.278 , pp. 378-383
    • Pearson, J.M.1    Schultze, A.E.2    Schwartz, K.A.3
  • 26
    • 0032708759 scopus 로고    scopus 로고
    • Proteinase-activated receptor-2 activating peptides induce leucocyte rolling, adhesion, and extravasation in vivo
    • Vergnolle N. Proteinase-activated receptor-2 activating peptides induce leucocyte rolling, adhesion, and extravasation in vivo. J Immunol 1999; 163: 5064-9.
    • (1999) J Immunol , vol.163 , pp. 5064-5069
    • Vergnolle, N.1
  • 27
    • 0029952336 scopus 로고    scopus 로고
    • Ligand cross-reactivity within the protease-activated receptor family
    • Blackhart BD, Emilsson K, Nguyen D, et al. Ligand cross-reactivity within the protease-activated receptor family. J Biol Chem 1996; 271: 16466-71.
    • (1996) J Biol Chem , vol.271 , pp. 16466-16471
    • Blackhart, B.D.1    Emilsson, K.2    Nguyen, D.3
  • 28
    • 0842328843 scopus 로고    scopus 로고
    • Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia
    • Pawlinski R, Pedersen B, Schabbauer G, et al. Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia. Blood 2004; 103: 1342-7.
    • (2004) Blood , vol.103 , pp. 1342-1347
    • Pawlinski, R.1    Pedersen, B.2    Schabbauer, G.3
  • 29
    • 0142183468 scopus 로고    scopus 로고
    • Protease-activated receptors 1 and 4 mediate thrombin signaling in endothelial cells
    • Katakaoka H, Hamilton JR, McKemy DD, et al. Protease-activated receptors 1 and 4 mediate thrombin signaling in endothelial cells. Blood 2003; 102: 3224-31.
    • (2003) Blood , vol.102 , pp. 3224-3231
    • Katakaoka, H.1    Hamilton, J.R.2    McKemy, D.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.