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Volumn 91, Issue 4, 2013, Pages 275-284

Inflammatory cytokine TNF-α inhibits Na+-glutamine cotransport in intestinal epithelial cells

Author keywords

B AT1 protein expression; B AT1 transcript abundance; Epithelial transport; Glutamine uptake; Post translational regulation; Proinflammatory mediators

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CARRIER PROTEIN; CASPASE 3; GENISTEIN; GLUTAMINE; MEMBRANE PROTEIN; SMALL INTERFERING RNA; SODIUM GLUTAMINE COTRANSPORTER; SODIUM ION; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84880799384     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/cjpp-2011-0488     Document Type: Article
Times cited : (7)

References (43)
  • 2
    • 33751094332 scopus 로고    scopus 로고
    • HO-2 provides endogenous protection against oxidativestress and apoptosis caused by TNF-α in cerebral vascular endothelial cells
    • doi:10.1152/ajpcell.00032.2006. PMID:16822952
    • Basuroy, S., Bhattacharya, S., Tcheranova, D., Qu, Y., Regan, R.F., Leffler, C.W., et al. 2006. HO-2 provides endogenous protection against oxidativestress and apoptosis caused by TNF-α in cerebral vascular endothelial cells. Am. J. Physiol. Cell Physiol. 291: C897-C908. doi:10.1152/ajpcell.00032.2006. PMID:16822952.
    • (2006) Am. J. Physiol. Cell Physiol , vol.291
    • Basuroy, S.1    Bhattacharya, S.2    Tcheranova, D.3    Qu, Y.4    Regan, R.F.5    Leffler, C.W.6
  • 3
    • 0142213140 scopus 로고    scopus 로고
    • Polyamines are required for activation of c-Jun NH2-terminal kinase and apoptosis in response to TNF-α in IEC-6 cells
    • doi:10.1152/ajpgi.00206.2003. PMID:12869386
    • Bhattacharya, S., Ray, R.M., Viar, M.J., and Johnson, L.R. 2003. Polyamines are required for activation of c-Jun NH2-terminal kinase and apoptosis in response to TNF-α in IEC-6 cells. Am. J. Physiol. Gastrointest. Liver Physiol. 285: G980-G991. doi:10.1152/ajpgi.00206.2003. PMID:12869386.
    • (2003) Am. J. Physiol. Gastrointest. Liver Physiol , vol.285
    • Bhattacharya, S.1    Ray, R.M.2    Viar, M.J.3    Johnson, L.R.4
  • 4
    • 0014912828 scopus 로고
    • Jejunal absorption of water and electrolytes in inflammatory bowel diseases
    • PMID:5485380
    • Binder, H.J., and Ptak, T. 1970. Jejunal absorption of water and electrolytes in inflammatory bowel diseases. J. Lab. Clin. Med. 76: 915-924. PMID:5485380.
    • (1970) J. Lab. Clin. Med , vol.76 , pp. 915-924
    • Binder, H.J.1    Ptak, T.2
  • 5
    • 0034843258 scopus 로고    scopus 로고
    • Recent molecular advances in mammalian Glutamine transport
    • PMID:11533296
    • Bode, B.P. 2001. Recent molecular advances in mammalian Glutamine transport. J. Nutr. 131: 2475-2485. PMID:11533296.
    • (2001) J. Nutr , vol.131 , pp. 2475-2485
    • Bode, B.P.1
  • 6
    • 0024390678 scopus 로고
    • Mechanisms of cell death
    • doi:10.1016/0165-6147(89)90027-8. PMID: 2672471
    • Boobis, A.R., Fawthrop, D.J., and Davies, D.S. 1989. Mechanisms of cell death. Trends Pharmacol. Sci. 10: 275-280. doi:10.1016/0165-6147(89)90027-8. PMID: 2672471.
    • (1989) Trends Pharmacol. Sci , vol.10 , pp. 275-280
    • Boobis, A.R.1    Fawthrop, D.J.2    Davies, D.S.3
  • 7
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • doi:10.1006/abio.1976.9999. PMID:942051
    • Bradford, M.M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254. doi:10.1006/abio.1976.9999. PMID:942051.
    • (1976) Anal. Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 8
    • 38349170961 scopus 로고    scopus 로고
    • Amino acid transport across mammalian intestinal and renal epithelia
    • doi:10.1152/physrev.00018.2006. PMID:18195088
    • Bröer, S. 2008. Amino acid transport across mammalian intestinal and renal epithelia. Physiol. Rev. 88: 249-286. doi:10.1152/physrev.00018.2006. PMID:18195088.
    • (2008) Physiol. Rev , vol.88 , pp. 249-286
    • Bröer, S.1
  • 9
    • 0038807482 scopus 로고    scopus 로고
    • The astroglial ASCT2 amino acid transporter as a mediator of glutamine efflux
    • doi:10.1046/j.1471-4159.1999.02184.x. PMID:10537079
    • Bröer, A., Brookes, N., Ganapathy, V., Dimmer, K.S., Wagner, C.A., Lang, F., et al. 1999. The astroglial ASCT2 amino acid transporter as a mediator of glutamine efflux. J. Neurochem. 73: 2184-2194. doi:10.1046/j.1471-4159.1999.02184.x. PMID:10537079.
    • (1999) J. Neurochem , vol.73 , pp. 2184-2194
    • Bröer, A.1    Brookes, N.2    Ganapathy, V.3    Dimmer, K.S.4    Wagner, C.A.5    Lang, F.6
  • 10
    • 0343868696 scopus 로고
    • Immunological regulation of electrolyte transport
    • Edited by E. Lebenthal and M.E. Duffey. Raven, New York, N.Y
    • Castro, G.A. 1990. Immunological regulation of electrolyte transport. In Textbook of secretory diarrhea. Edited by E. Lebenthal and M.E. Duffey. Raven, New York, N.Y. pp. 31-46.
    • (1990) Textbook of Secretory Diarrhea , pp. 31-46
    • Castro, G.A.1
  • 11
    • 84864742367 scopus 로고    scopus 로고
    • Intestinal peptidases form functional complexes with the neutral amino acid transporter
    • doi:10.1042/BJ20120307. PMID:22677001
    • Fairweather, S.J., Bröer, A., Omar, L.M., and Bröer, S. 2012. Intestinal peptidases form functional complexes with the neutral amino acid transporter B0AT1. Biochem. J. 446: 135-148. doi:10.1042/BJ20120307. PMID:22677001.
    • (2012) B0AT1. Biochem. J , vol.446 , pp. 135-148
    • Fairweather, S.J.1    Bröer, A.2    Omar, L.M.3    Bröer, S.4
  • 12
    • 0033927611 scopus 로고    scopus 로고
    • Glutamine and arginine: Immunonutrients for improved health
    • doi:10.1097/00005768-200007001-00002. PMID:10910294
    • Field, C.J., Johnson, I., and Pratt, V.C. 2000. Glutamine and arginine: immunonutrients for improved health. Med. Sci. Sports Exerc. 32: S377-S388. doi:10.1097/00005768-200007001-00002. PMID:10910294.
    • (2000) Med. Sci. Sports Exerc , vol.32
    • Field, C.J.1    Johnson, I.2    Pratt, V.C.3
  • 13
    • 0020698220 scopus 로고
    • +-ATPase in plasma membrane preparations: Increasing the permeability of membrane vesicles using sodium dodecyl sulphate buffered with bovine serum albumin. Anal
    • doi:10.1016/0003-2697(83)90356-1. PMID:6303151
    • +-ATPase in plasma membrane preparations: increasing the permeability of membrane vesicles using sodium dodecyl sulphate buffered with bovine serum albumin. Anal. Biochem. 128: 159-163. doi:10.1016/0003-2697(83)90356-1. PMID:6303151.
    • (1983) Biochem , vol.128 , pp. 159-163
    • Forbush, B.1
  • 14
    • 0035819495 scopus 로고    scopus 로고
    • The modulatory role played by TNF-alpha and IL-1 beta in the inflammatory responses induced by carrageenan in the mouse model of pleurisy
    • doi:10.1006/cyto.2000.0816. PMID:11161459
    • Frode, T.S., Souza, G.E., and Calixto, J.B. 2001. The modulatory role played by TNF-alpha and IL-1 beta in the inflammatory responses induced by carrageenan in the mouse model of pleurisy. Cytokine, 13: 162-168. doi:10.1006/cyto.2000.0816. PMID:11161459.
    • (2001) Cytokine , vol.13 , pp. 162-168
    • Frode, T.S.1    Souza, G.E.2    Calixto, J.B.3
  • 15
    • 0000273754 scopus 로고
    • Intestinal transport of amino acids and peptides
    • 3rd ed. Edited by L.R. Johnson. Raven, New York, N.Y
    • Ganapathy, V., Bransch, M., and Leibach, F.H. 1994. Intestinal transport of amino acids and peptides. In Physiology of the Gastrointestinal Tract, 3rd ed. Edited by L.R. Johnson. Raven, New York, N.Y. pp. 1773-1794.
    • (1994) Physiology of the Gastrointestinal Tract , pp. 1773-1794
    • Ganapathy, V.1    Bransch, M.2    Leibach, F.H.3
  • 16
    • 0642283970 scopus 로고    scopus 로고
    • Regulation of proliferation, survival and apoptosis by members of the TNF superfamily. Biochem
    • doi:10.1016/S0006-2952(03)00490-8. PMID:14555214
    • Gaur, U., and Aggarwal, B.B. 2003. Regulation of proliferation, survival and apoptosis by members of the TNF superfamily. Biochem. Pharmacol. 66: 1403-1408. doi:10.1016/S0006-2952(03)00490-8. PMID:14555214.
    • (2003) Pharmacol , vol.66 , pp. 1403-1408
    • Gaur, U.1    Aggarwal, B.B.2
  • 17
    • 0031937067 scopus 로고    scopus 로고
    • Small bowel enteropathy: Role of intraepithelial lymphocytes and of cytokines (IL-12, IFN-γ, TNF) in the induction of epithelial cell death and renewal
    • doi:10.1002/(SICI)1521-4141(199802)28:02<730::AID-IMMU730>3.3.CO;2-L. PMID:9521083
    • Guy-Grand, D., DiSanto, J.P., Henchoz, P., Malassis-Seris, M., and Vassalli, P. 1998. Small bowel enteropathy: role of intraepithelial lymphocytes and of cytokines (IL-12, IFN-γ, TNF) in the induction of epithelial cell death and renewal. Eur. J. Immunol. 28: 730-744. doi:10.1002/(SICI)1521-4141(199802)28:02<730::AID-IMMU730>3.3.CO;2-L. PMID:9521083.
    • (1998) Eur. J. Immunol , vol.28 , pp. 730-744
    • Guy-Grand, D.1    Disanto, J.P.2    Henchoz, P.3    Malassis-Seris, M.4    Vassalli, P.5
  • 18
    • 0028589378 scopus 로고
    • Regulation of cell number in the gastrointestinal tract: The importance of apoptosis
    • PMID:7706406
    • Hall, P.A., Coates, P.J., Ansari, B., and Hopwood, D. 1994. Regulation of cell number in the gastrointestinal tract: the importance of apoptosis. J. Cell Sci. 107: 3569-3577. PMID:7706406.
    • (1994) J. Cell Sci , vol.107 , pp. 3569-3577
    • Hall, P.A.1    Coates, P.J.2    Ansari, B.3    Hopwood, D.4
  • 19
    • 0021351203 scopus 로고
    • Oxygen toxicity, oxygen radicals, transition metals and disease
    • PMID:6326753
    • Halliwell, B., and Gutteridge, J.M.C. 1984. Oxygen toxicity, oxygen radicals, transition metals and disease. J. Biochem. 219:1-24. PMID:6326753.
    • (1984) J. Biochem , vol.219 , pp. 1-24
    • Halliwell, B.1    Gutteridge, J.M.C.2
  • 20
    • 0000551060 scopus 로고
    • Membrane transport mechanisms for hexoses and amino acids in the small intestine
    • 2nd ed. Edited by L.R. Johnson. Raven, New York, N.Y
    • Hopfer, U. 1987. Membrane transport mechanisms for hexoses and amino acids in the small intestine. In Physiology of the gastrointestinal tract, 2nd ed. Edited by L.R. Johnson. Raven, New York, N.Y. pp. 1499-1526.
    • (1987) Physiology of the Gastrointestinal Tract , pp. 1499-1526
    • Hopfer, U.1
  • 21
    • 42049118512 scopus 로고    scopus 로고
    • TNF-alpha/cycloheximide-induced poptosis in intestinal epithelial cells requires Rac1-regulated reactive oxygen species
    • doi:10.1152/ajpgi.00219.2007. PMID: 18218673
    • Jin, S., Ray, R.M., and Johnson, L.R. 2008. TNF-alpha/cycloheximide-induced poptosis in intestinal epithelial cells requires Rac1-regulated reactive oxygen species. Am. J. Physiol. 294: G928-G937. doi:10.1152/ajpgi.00219.2007. PMID: 18218673.
    • (2008) Am. J. Physiol , vol.294
    • Jin, S.1    Ray, R.M.2    Johnson, L.R.3
  • 22
    • 0030970550 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha regulates proliferation in a mouse intestinal cell line
    • : 10.1016/S0016-5085(97)70135-5. PMID:9098007
    • Kaiser, G.C., and Polk, D.B. 1997. Tumor necrosis factor alpha regulates proliferation in a mouse intestinal cell line. Gastroenterology, 112: 1231-1240. doi: 10.1016/S0016-5085(97)70135-5. PMID:9098007.
    • (1997) Gastroenterology , vol.112 , pp. 1231-1240
    • Kaiser, G.C.1    Polk, D.B.2
  • 23
    • 14844327760 scopus 로고    scopus 로고
    • Reactiveoxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases
    • : 10.1016/j.cell.2004.12.041. PMID:15766528
    • Kamata, H., Honda, S., Maeda, S., Chang, L., Hirata, H., and Karin, M. 2005. Reactiveoxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell, 120: 649-661. doi: 10.1016/j.cell.2004.12.041. PMID:15766528.
    • (2005) Cell , vol.120 , pp. 649-661
    • Kamata, H.1    Honda, S.2    Maeda, S.3    Chang, L.4    Hirata, H.5    Karin, M.6
  • 24
    • 0036892753 scopus 로고    scopus 로고
    • Regulation of taurine transport at the blood-brain barrier by tumor necrosis factor-alpha, taurine and hypertonicity
    • doi:10.1046/j.1471-4159.2002.01223.x. PMID:12437590
    • Kang, Y.S., Ohtsuki, S., Takanaga, H., Tomi, M., Hosoya, K., and Terasaki, T. 2002. Regulation of taurine transport at the blood-brain barrier by tumor necrosis factor-alpha, taurine and hypertonicity. J. Neurochem. 83: 1188-1195. doi:10.1046/j.1471-4159.2002.01223.x. PMID:12437590.
    • (2002) J. Neurochem , vol.83 , pp. 1188-1195
    • Kang, Y.S.1    Ohtsuki, S.2    Takanaga, H.3    Tomi, M.4    Hosoya, K.5    Terasaki, T.6
  • 25
    • 0034518908 scopus 로고    scopus 로고
    • Glutamine
    • doi:10.1007/s002680010269. PMID:11193715
    • Labow, B.I., and Souba, W.W. 2000. Glutamine. World J. Surg. 24: 1503-1513. doi:10.1007/s002680010269. PMID:11193715.
    • (2000) World J. Surg , vol.24 , pp. 1503-1513
    • Labow, B.I.1    Souba, W.W.2
  • 26
    • 0032896832 scopus 로고    scopus 로고
    • Rat liver endothelial cell glutamine transporter and glutaminase expression contrast with parenchymal cells
    • PMID:10070052
    • Lohmann, R., Souba, W.W., and Bode, B.P. 1999. Rat liver endothelial cell glutamine transporter and glutaminase expression contrast with parenchymal cells. Am. J. Physiol. 276: G743-G750. PMID:10070052.
    • (1999) Am. J. Physiol , vol.276
    • Lohmann, R.1    Souba, W.W.2    Bode, B.P.3
  • 27
    • 0033886814 scopus 로고    scopus 로고
    • Recombinant human interleukin-11 modulates ion transport and mucosal inflammation in the small intestine and colon
    • doi:10.1038/labinvest.3780135. PMID: 10950118
    • Meerveld, B.G., Tyler, K., and Keith, J.C. 2000. Recombinant human interleukin-11 modulates ion transport and mucosal inflammation in the small intestine and colon. Lab. Investig. 80: 1269-1280. doi:10.1038/labinvest.3780135. PMID: 10950118.
    • (2000) Lab. Investig , vol.80 , pp. 1269-1280
    • Meerveld, B.G.1    Tyler, K.2    Keith, J.C.3
  • 28
    • 79951673768 scopus 로고    scopus 로고
    • Berberine attenuates lipopolysaccharide-induced impairments of intestinal Glutamine transport and glutaminase activity in rat
    • doi:10.1016/j.fitote.2010.11.007. PMID:21073932
    • Niu, L., Qiao, W., Hu, Z., Li, N., Huang, Q., Gong, J., et al. 2010. Berberine attenuates lipopolysaccharide-induced impairments of intestinal Glutamine transport and glutaminase activity in rat. Fitoterapia, 82: 323-330. doi:10.1016/j.fitote.2010.11.007. PMID:21073932.
    • (2010) Fitoterapia , vol.82 , pp. 323-330
    • Niu, L.1    Qiao, W.2    Hu, Z.3    Li, N.4    Huang, Q.5    Gong, J.6
  • 29
    • 0018394382 scopus 로고
    • Epithelioid cell cultures from rat small intestine. Characterization by morphologic and immunologic criteria
    • doi:10.1083/jcb.80.2.248. PMID:88453
    • Quaroni, A., Wands, J., Trelstad, R.L., and Isselbacher, K.J. 1979. Epithelioid cell cultures from rat small intestine. Characterization by morphologic and immunologic criteria. J. Cell Biol. 80: 248-265. doi:10.1083/jcb.80.2.248. PMID:88453.
    • (1979) J. Cell Biol , vol.80 , pp. 248-265
    • Quaroni, A.1    Wands, J.2    Trelstad, R.L.3    Isselbacher, K.J.4
  • 30
    • 79955556337 scopus 로고    scopus 로고
    • Regulation of JNK activity in the apoptotic response of intestinal epithelial cells
    • doi:10.1152/ajpgi.00405.2010. PMID:21350193
    • Ray, R.M., Shi, J., Bavaria, M.N., and Johnson, L.R. 2011. Regulation of JNK activity in the apoptotic response of intestinal epithelial cells. Am. J. Physiol. 300: G761-G770. doi:10.1152/ajpgi.00405.2010. PMID:21350193.
    • (2011) Am. J. Physiol , vol.300
    • Ray, R.M.1    Shi, J.2    Bavaria, M.N.3    Johnson, L.R.4
  • 31
    • 0033600028 scopus 로고    scopus 로고
    • TNF-α induced IEC-6 cell apoptosis requires activation of ICE caspases whereas complete inhibition of the caspase leads to necrotic cell death
    • doi:10.1006/bbrc.1999.0734. PMID:10381360
    • Ruemmele, F.M., Dionne, S., Levy, E., and Seidman, E. 1999. TNF-α induced IEC-6 cell apoptosis requires activation of ICE caspases whereas complete inhibition of the caspase leads to necrotic cell death. Biochem. Biophys. Res. Commun. 260: 159-166. doi:10.1006/bbrc.1999.0734. PMID:10381360.
    • (1999) Biochem. Biophys. Res. Commun , vol.260 , pp. 159-166
    • Ruemmele, F.M.1    Dionne, S.2    Levy, E.3    Seidman, E.4
  • 32
    • 0040813817 scopus 로고
    • Mechanisms of diarrhea in inflammation and hypersensitivity: Immune system modulation of intestinal transport
    • Edited by M. Field. Elsevier Science, New York, N.Y
    • Sartor, R.B., and Powell, D.W. 1991. Mechanisms of diarrhea in inflammation and hypersensitivity: immune system modulation of intestinal transport. In Diarrheal Diseases. Edited by M. Field. Elsevier Science, New York, N.Y. pp. 75-114.
    • (1991) Diarrheal Diseases , pp. 75-114
    • Sartor, R.B.1    Powell, D.W.2
  • 34
    • 67651068788 scopus 로고    scopus 로고
    • Differential ferritin expression is associated with iron deficiency in coeliac disease
    • doi:10.1097/MEG.0b013e328308676b. PMID:19404207
    • Sharma, N., Begum, J., Eksteen, B., Elagib, A., Brookes, M., Cooper, B.T., et al. 2009. Differential ferritin expression is associated with iron deficiency in coeliac disease. Eur. J. Gastroenterol. Hepatol. 21: 794-804. doi:10.1097/MEG.0b013e328308676b. PMID:19404207.
    • (2009) Eur. J. Gastroenterol. Hepatol , vol.21 , pp. 794-804
    • Sharma, N.1    Begum, J.2    Eksteen, B.3    Elagib, A.4    Brookes, M.5    Cooper, B.T.6
  • 35
    • 0142201656 scopus 로고
    • Glutamine metabolism in catabolic states
    • Souba, W.W. 1986. Glutamine metabolism in catabolic states. Infect. Surg. 5: 641-650.
    • (1986) Infect. Surg , vol.5 , pp. 641-650
    • Souba, W.W.1
  • 36
    • 0022254742 scopus 로고
    • Glutamine metabolism by the intestinal tract
    • doi:10.1177/0148607185009005608. PMID:3900455
    • Souba, W.W., Smith, R.J., and Wilmore, D.W. 1985. Glutamine metabolism by the intestinal tract. JPEN J. Parenter. Enteral. Nutr. 9: 608-617. doi:10.1177/0148607185009005608. PMID:3900455.
    • (1985) JPEN J. Parenter. Enteral. Nutr , vol.9 , pp. 608-617
    • Souba, W.W.1    Smith, R.J.2    Wilmore, D.W.3
  • 37
    • 84880808310 scopus 로고    scopus 로고
    • Na-Glutamine co-transport is uniquely regulated in villus and crypt cells during chronic intestinal inflammation in rabbits
    • doi:10.1053/S0016-5085(05)00348-3
    • Talukder, J.R., Coon, S., and Sundaram, U. 2005. Na-Glutamine co-transport is uniquely regulated in villus and crypt cells during chronic intestinal inflammation in rabbits. Gastroenterology, 128: A12-A12. doi:10.1053/S0016-5085(05)00348-3.
    • (2005) Gastroenterology , vol.128
    • Talukder, J.R.1    Coon, S.2    Sundaram, U.3
  • 38
    • 51149102903 scopus 로고    scopus 로고
    • Identification and characterization of rabbit small intestinal villus cell brush border membrane Na-glutamine cotransporter
    • doi:10.1152/ajpgi.00606.2007. PMID:18436625
    • Talukder, J.R., Kekuda, R., Saha, P., Arthur, S., and Sundaram, U. 2008a. Identification and characterization of rabbit small intestinal villus cell brush border membrane Na-glutamine cotransporter. Am. J. Physiol. 295: G7-G15. doi:10.1152/ajpgi.00606.2007. PMID:18436625.
    • (2008) Am. J. Physiol , vol.295
    • Talukder, J.R.1    Kekuda, R.2    Saha, P.3    Arthur, S.4    Sundaram, U.5
  • 39
    • 51149111446 scopus 로고    scopus 로고
    • Mechanism of leukotriene D4 inhibition of Na-alanine cotransport in intestinal epithelial cells
    • doi:10.1152/ajpgi.00498.2007. PMID:18436626
    • Talukder, J.R., Kekuda, R., Saha, P., and Sundaram, U. 2008b. Mechanism of leukotriene D4 inhibition of Na-alanine cotransport in intestinal epithelial cells. Am. J. Physiol. 295: G1-G6. doi:10.1152/ajpgi.00498.2007. PMID:18436626.
    • (2008) Am. J. Physiol , vol.295
    • Talukder, J.R.1    Kekuda, R.2    Saha, P.3    Sundaram, U.4
  • 40
    • 48249131346 scopus 로고    scopus 로고
    • Functional characterization, localization and molecular identification of rabbit intestinal N-amino acid transporter
    • doi:10.1152/ajpgi.00578.2007. PMID:18388187
    • Talukder, J.R., Kekuda, R., Saha, P., Prasad, P.D., Ganapathy, V., and Sundaram, U. 2008c. Functional characterization, localization and molecular identification of rabbit intestinal N-amino acid transporter. Am. J. Physiol. 294: G1301-G1310. doi:10.1152/ajpgi.00578.2007. PMID:18388187.
    • (2008) Am. J. Physiol , vol.294
    • Talukder, J.R.1    Kekuda, R.2    Saha, P.3    Prasad, P.D.4    Ganapathy, V.5    Sundaram, U.6
  • 41
    • 0032463715 scopus 로고    scopus 로고
    • Generation of inflammatory cytokines in zymosan-induced pleurisy in rats: TNF induces IL-6 and cytokineinduced neutrophil chemoattractant (CINC) in vivo
    • doi:10.1006/cyto.1998.0376. PMID:10049519
    • Utsunomiya, I., Ito, M., and Oh-ishi, S. 1998. Generation of inflammatory cytokines in zymosan-induced pleurisy in rats: TNF induces IL-6 and cytokineinduced neutrophil chemoattractant (CINC) in vivo. Cytokine, 10: 956-963. doi:10.1006/cyto.1998.0376. PMID:10049519.
    • (1998) Cytokine , vol.10 , pp. 956-963
    • Utsunomiya, I.1    Ito, M.2    Oh-Ishi, S.3
  • 42
    • 69749109136 scopus 로고    scopus 로고
    • Roux-en-Y gastric bypass alters small intestine glutamine transport in the obese Zucker rat
    • doi:10.1152/ajpgi.00104.2009. PMID: 19556357
    • Wolff, B.S., Meirelles, K., Meng, Q., Pan, M., and Cooney, R.N. 2009. Roux-en-Y gastric bypass alters small intestine glutamine transport in the obese Zucker rat. Am. J. Physiol. 297: G594-G601. doi:10.1152/ajpgi.00104.2009. PMID: 19556357.
    • (2009) Am. J. Physiol , vol.297
    • Wolff, B.S.1    Meirelles, K.2    Meng, Q.3    Pan, M.4    Cooney, R.N.5
  • 43
    • 0034644753 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha generates reactive oxygen species via a cytosolic phospholipase A2-linked cascade
    • doi:10.1074/jbc.M005638200. PMID:10934206
    • Woo, C.H., Eom, Y.W., Yoo, M.H., You, H.J., Han, H.J., Song, W.K., et al. 2000. Tumor necrosis factor-alpha generates reactive oxygen species via a cytosolic phospholipase A2-linked cascade. J. Biol. Chem. 275: 32357-32362. doi:10.1074/jbc.M005638200. PMID:10934206.
    • (2000) J. Biol. Chem , vol.275 , pp. 32357-32362
    • Woo, C.H.1    Eom, Y.W.2    Yoo, M.H.3    You, H.J.4    Han, H.J.5    Song, W.K.6


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