ß-Blocker Timolol Prevents Arrhythmogenic Ca2+ Release and Normalizes Ca2+ and Zn2+ Dyshomeostasis in Hyperglycemic Rat Heart

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Tuncay, Erkan ^a   Okatan, Esma N ^a   Vassort, Guy ^b   Turan, Belma ^a  

^a ANKARA UNIVERSITY   (Turkey)

^b HÔPITAL ARNAUD DE VILLENEUVE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM ION; CALSTABIN 2; FK 506 BINDING PROTEIN; GLUTATHIONE; PHOSPHOLAMBAN; RYANODINE RECEPTOR 2; SODIUM CALCIUM EXCHANGE PROTEIN; STREPTOZOCIN; TIMOLOL; UNCLASSIFIED DRUG; ZINC ION;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL SIZE; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; HEART ARRHYTHMIA; HEART LEFT VENTRICLE CONTRACTILITY; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; HEART PROTECTION; HYPERGLYCEMIA; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TIME; MALE; NONHUMAN; OXIDATION REDUCTION STATE; PROTEIN DEPLETION; PROTEIN PHOSPHORYLATION; RAT; SARCOPLASMIC RETICULUM; STREPTOZOCIN DIABETES; TREATMENT DURATION; WESTERN BLOTTING;

ACTION POTENTIALS; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; ANTIOXIDANTS; CALCIUM; CALCIUM-BINDING PROTEINS; DIABETES MELLITUS, EXPERIMENTAL; HEART; HYPERGLYCEMIA; INTRACELLULAR SPACE; MALE; MYOCARDIUM; MYOCYTES, CARDIAC; PHOSPHORYLATION; RATS; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; SODIUM-CALCIUM EXCHANGER; TIMOLOL; ZINC;

EID: 84880788900     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0071014     Document Type: Article

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