메뉴 건너뛰기




Volumn 45, Issue 4, 2004, Pages 346-353

Divergent Consequences Arise from Metallothionein Overexpression in Astrocytes: Zinc Buffering and Oxidant-Induced Zinc Release

Author keywords

2,2 dithiodipyridine; Glia; Oxidative stress; Pyrithione

Indexed keywords

2,2' DITHIODIPYRIDINE; ADENOVIRUS VECTOR; BINDING PROTEIN; BUFFER; HEAVY METAL; METALLOTHIONEIN; OXIDIZING AGENT; PYRITHIONE; THIOL DERIVATIVE; ZINC;

EID: 1542619550     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/glia.10332     Document Type: Article
Times cited : (51)

References (38)
  • 3
    • 0031770844 scopus 로고    scopus 로고
    • Calcium-sensitive fluorescent dyes can report increases in intracellular free zinc concentration in cultured forebrain neurons
    • Cheng C, Reynolds IJ. 1998. Calcium-sensitive fluorescent dyes can report increases in intracellular free zinc concentration in cultured forebrain neurons. J Neurochem 71:2401-2410.
    • (1998) J Neurochem , vol.71 , pp. 2401-2410
    • Cheng, C.1    Reynolds, I.J.2
  • 4
    • 0017727928 scopus 로고
    • Studies on the synthesis and metabolism of zinc-thionein in rats
    • Cherian MG. 1977. Studies on the synthesis and metabolism of zinc-thionein in rats. J Nutr 107:965-972.
    • (1977) J Nutr , vol.107 , pp. 965-972
    • Cherian, M.G.1
  • 5
    • 0023833925 scopus 로고
    • Zinc neurotoxicity in cortical cell culture
    • Choi DW, Yokoyama M, Koh J. 1988. Zinc neurotoxicity in cortical cell culture. Neuroscience 24:67-79.
    • (1988) Neuroscience , vol.24 , pp. 67-79
    • Choi, D.W.1    Yokoyama, M.2    Koh, J.3
  • 6
    • 0032514150 scopus 로고    scopus 로고
    • Nitric oxide generators produce accumulation of chelatable zinc in hippocampal neuronal perikarya
    • Cuajungco MP, Lees GJ. 1998. Nitric oxide generators produce accumulation of chelatable zinc in hippocampal neuronal perikarya. Brain Res 799:118-129.
    • (1998) Brain Res , vol.799 , pp. 118-129
    • Cuajungco, M.P.1    Lees, G.J.2
  • 8
    • 0036765589 scopus 로고    scopus 로고
    • A reevaluation of neuronal zinc measurements: Artifacts associated with high intracellular dye concentration
    • Dineley KE, Malaiyandi LM, Reynolds IJ. 2002. A reevaluation of neuronal zinc measurements: artifacts associated with high intracellular dye concentration. Mol Pharmacol 62:618-627.
    • (2002) Mol Pharmacol , vol.62 , pp. 618-627
    • Dineley, K.E.1    Malaiyandi, L.M.2    Reynolds, I.J.3
  • 9
    • 0023072503 scopus 로고
    • Analysis of the detoxification of heavy metal ions by mouse metallothionein
    • Durnam DM, Palmiter RD. 1987. Analysis of the detoxification of heavy metal ions by mouse metallothionein. Experientia 52(suppl): 457-463.
    • (1987) Experientia , vol.52 , Issue.SUPPL. , pp. 457-463
    • Durnam, D.M.1    Palmiter, R.D.2
  • 10
    • 0023918015 scopus 로고
    • Loss of zinc staining from hippocampal mossy fibers during kainic acid induced seizures: A histofluorescence study
    • Frederickson CJ, Hernandez MD, Goik SA, Morton JD, McGinty JF. 1988. Loss of zinc staining from hippocampal mossy fibers during kainic acid induced seizures: a histofluorescence study. Brain Res 446:383-386.
    • (1988) Brain Res , vol.446 , pp. 383-386
    • Frederickson, C.J.1    Hernandez, M.D.2    Goik, S.A.3    Morton, J.D.4    McGinty, J.F.5
  • 11
    • 0035872463 scopus 로고    scopus 로고
    • Roles of the metallothionein family of proteins in the central nervous system
    • Hidalgo J, Aschner M, Zatta P, Vasak M. 2001. Roles of the metallothionein family of proteins in the central nervous system. Brain Res Bull 55:133-145.
    • (2001) Brain Res Bull , vol.55 , pp. 133-145
    • Hidalgo, J.1    Aschner, M.2    Zatta, P.3    Vasak, M.4
  • 12
    • 0032584186 scopus 로고    scopus 로고
    • Control of zinc transfer between thionein, metallothionein, and zinc proteins
    • Jacob C, Maret W, Vallee BL. 1998. Control of zinc transfer between thionein, metallothionein, and zinc proteins. Proc Natl Acad Sci USA 95:3489-3494.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3489-3494
    • Jacob, C.1    Maret, W.2    Vallee, B.L.3
  • 13
    • 0034604723 scopus 로고    scopus 로고
    • Superoxide-induced stimulation of protein kinase C via thiol modification and modulation of zinc content
    • Knapp LT, Klann E. 2000. Superoxide-induced stimulation of protein kinase C via thiol modification and modulation of zinc content. J Biol Chem 275:24136-24145.
    • (2000) J Biol Chem , vol.275 , pp. 24136-24145
    • Knapp, L.T.1    Klann, E.2
  • 14
    • 0023905988 scopus 로고
    • Zinc alters excitatory amino acid neurotoxicity on cortical neurons
    • Koh JY, Choi DW. 1988. Zinc alters excitatory amino acid neurotoxicity on cortical neurons. J Neurosci 8:2164-2171.
    • (1988) J Neurosci , vol.8 , pp. 2164-2171
    • Koh, J.Y.1    Choi, D.W.2
  • 15
    • 0028343364 scopus 로고
    • Zinc toxicity on cultured cortical neurons: Involvement of N-methyl-D-aspartate receptors
    • Koh JY, Choi DW. 1994. Zinc toxicity on cultured cortical neurons: involvement of N-methyl-D-aspartate receptors. Neuroscience 60:1049-1057.
    • (1994) Neuroscience , vol.60 , pp. 1049-1057
    • Koh, J.Y.1    Choi, D.W.2
  • 16
    • 0029777299 scopus 로고    scopus 로고
    • The role of zinc in selective neuronal death after transient global cerebral ischemia
    • Koh JY, Suh SW, Gwag BJ, He YY, Hsu CY, Choi DW. 1996. The role of zinc in selective neuronal death after transient global cerebral ischemia. Science 272:1013-1016.
    • (1996) Science , vol.272 , pp. 1013-1016
    • Koh, J.Y.1    Suh, S.W.2    Gwag, B.J.3    He, Y.Y.4    Hsu, C.Y.5    Choi, D.W.6
  • 17
    • 0030061160 scopus 로고    scopus 로고
    • Induction of metallothionein mRNA and protein in murine astrocyte cultures
    • Kramer KK, Liu J, Choudhuri S, Klaassen CD. 1996. Induction of metallothionein mRNA and protein in murine astrocyte cultures. Toxicol Appl Pharmacol 136:94-100.
    • (1996) Toxicol Appl Pharmacol , vol.136 , pp. 94-100
    • Kramer, K.K.1    Liu, J.2    Choudhuri, S.3    Klaassen, C.D.4
  • 18
    • 0037101622 scopus 로고    scopus 로고
    • The relationship between intracellular free iron and cell injury in cultured neurons, astrocytes, and oligodendrocytes
    • Kress GJ, Dineley KE, Reynolds IJ. 2002. The relationship between intracellular free iron and cell injury in cultured neurons, astrocytes, and oligodendrocytes. J Neurosci 22:5848-5855.
    • (2002) J Neurosci , vol.22 , pp. 5848-5855
    • Kress, G.J.1    Dineley, K.E.2    Reynolds, I.J.3
  • 19
    • 0034602175 scopus 로고    scopus 로고
    • The transcription factor MTF-1 mediates metal regulation of the mouse ZnT1 gene
    • Langmade SJ, Ravindra R, Daniels PJ, Andrews GK. 2000. The transcription factor MTF-1 mediates metal regulation of the mouse ZnT1 gene. J Biol Chem 275:34803-34809.
    • (2000) J Biol Chem , vol.275 , pp. 34803-34809
    • Langmade, S.J.1    Ravindra, R.2    Daniels, P.J.3    Andrews, G.K.4
  • 20
    • 0026486270 scopus 로고
    • Stable transfection of calbindin-D28k into the GH3 cell line alters calcium currents and intracellular calcium homeostasis
    • Lledo PM, Somasundaram B, Morton AJ, Emson PC, Mason WT. 1992. Stable transfection of calbindin-D28k into the GH3 cell line alters calcium currents and intracellular calcium homeostasis. Neuron 9:943-954.
    • (1992) Neuron , vol.9 , pp. 943-954
    • Lledo, P.M.1    Somasundaram, B.2    Morton, A.J.3    Emson, P.C.4    Mason, W.T.5
  • 21
    • 0031194657 scopus 로고    scopus 로고
    • Characterization of zinc-induced neuronal death in primary cultures of rat cerebellar granule cells
    • Manev H, Kharlamov E, Uz T, Mason RP, Cagnoli CM. 1997. Characterization of zinc-induced neuronal death in primary cultures of rat cerebellar granule cells. Exp Neurol 146:171-178.
    • (1997) Exp Neurol , vol.146 , pp. 171-178
    • Manev, H.1    Kharlamov, E.2    Uz, T.3    Mason, R.P.4    Cagnoli, C.M.5
  • 22
    • 0032584166 scopus 로고    scopus 로고
    • Thiolate ligands in metallothionein confer redox activity on zinc clusters
    • Maret W, Vallee BL. 1998. Thiolate ligands in metallothionein confer redox activity on zinc clusters. Proc Natl Acad Sci USA 95:3478-3482.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3478-3482
    • Maret, W.1    Vallee, B.L.2
  • 24
    • 0031910161 scopus 로고    scopus 로고
    • Calbindin-D28k buffers intracellular calcium and promotes resistance to degeneration in PC12 cells
    • McMahon A, Wong BS, Iacopino AM, Ng MC, Chi S, German DC. 1998. Calbindin-D28k buffers intracellular calcium and promotes resistance to degeneration in PC12 cells. Brain Res Mol Brain Res 54:56-63.
    • (1998) Brain Res Mol Brain Res , vol.54 , pp. 56-63
    • McMahon, A.1    Wong, B.S.2    Iacopino, A.M.3    Ng, M.C.4    Chi, S.5    German, D.C.6
  • 25
    • 0035968001 scopus 로고    scopus 로고
    • Femtomolar sensitivity of metalloregulatory proteins controlling zinc homeostasis
    • Outten CE, O'Halloran TV. 2001. Femtomolar sensitivity of metalloregulatory proteins controlling zinc homeostasis. Science 292:2488-2492.
    • (2001) Science , vol.292 , pp. 2488-2492
    • Outten, C.E.1    O'Halloran, T.V.2
  • 26
    • 0023071221 scopus 로고
    • Molecular biology of metallothionein gene expression
    • Palmiter RD. 1987. Molecular biology of metallothionein gene expression. Experientia 52(suppl):63-80.
    • (1987) Experientia , vol.52 , Issue.SUPPL. , pp. 63-80
    • Palmiter, R.D.1
  • 27
    • 0028125990 scopus 로고
    • Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with a constitutively active transcription factor, MTF-1
    • Palmiter RD. 1994. Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with a constitutively active transcription factor, MTF-1. Proc Natl Acad Sci USA 91:1219-1223.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 1219-1223
    • Palmiter, R.D.1
  • 29
    • 0035069828 scopus 로고    scopus 로고
    • Calcium buffering and protection from excitotoxic cell death by exogenous calbindin-D28k in HEK 293 cells
    • Rintoul GL, Raymond LA, Baimbridge KG. 2001. Calcium buffering and protection from excitotoxic cell death by exogenous calbindin-D28k in HEK 293 cells. Cell Calcium 29:277-287.
    • (2001) Cell Calcium , vol.29 , pp. 277-287
    • Rintoul, G.L.1    Raymond, L.A.2    Baimbridge, K.G.3
  • 30
    • 0029156314 scopus 로고
    • Metallothionein induction in neonatal rat primary astrocyte cultures protects against methylmercury cytotoxicity
    • Rising L, Vitarella D, Kimelberg HK, Aschner M. 1995. Metallothionein induction in neonatal rat primary astrocyte cultures protects against methylmercury cytotoxicity. J Neurochem 65:1562-1568.
    • (1995) J Neurochem , vol.65 , pp. 1562-1568
    • Rising, L.1    Vitarella, D.2    Kimelberg, H.K.3    Aschner, M.4
  • 32
    • 0026658737 scopus 로고
    • Overexpression of metallothionein confers resistance to the cytotoxic effect of TNF with cadmium in MCF-7 breast carcinoma cells
    • Sciavolino PJ, Lee TH, Vilcek J. 1992. Overexpression of metallothionein confers resistance to the cytotoxic effect of TNF with cadmium in MCF-7 breast carcinoma cells. Lymphokine Cytokine Res 11:265-270.
    • (1992) Lymphokine Cytokine Res , vol.11 , pp. 265-270
    • Sciavolino, P.J.1    Lee, T.H.2    Vilcek, J.3
  • 33
    • 0026346245 scopus 로고
    • Ligand substitution and sulfhydryl reactivity of metallothionein
    • Shaw CF III, Savas MM, Petering DH. 1991. Ligand substitution and sulfhydryl reactivity of metallothionein. Methods Enzymol 205:401-414.
    • (1991) Methods Enzymol , vol.205 , pp. 401-414
    • Shaw III, C.F.1    Savas, M.M.2    Petering, D.H.3
  • 38
    • 0027536881 scopus 로고
    • AMPA receptor activation potentiates zinc neurotoxicity
    • Weiss JH, Hartley DM, Koh JY, Choi DW. 1993. AMPA receptor activation potentiates zinc neurotoxicity. Neuron 10:43-49.
    • (1993) Neuron , vol.10 , pp. 43-49
    • Weiss, J.H.1    Hartley, D.M.2    Koh, J.Y.3    Choi, D.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.