The BTB-zinc Finger Transcription Factor Abrupt Acts as an Epithelial Oncogene in Drosophila melanogaster through Maintaining a Progenitor-like Cell State

PLoS Genetics

Volumn 9, Issue 7, 2013, Pages

  Turkel, Nezaket ^a,b   Sahota, Virender K ^a   Bolden, Jessica E ^a   Goulding, Karen R ^a   Doggett, Karen ^a   Willoughby, Lee F ^a   Blanco, Enrique ^c   Martin Blanco, Enrique ^d   Corominas, Montserrat ^c   Ellul, Jason ^a   Aigaki, Toshiro ^e   Richardson, Helena E ^a,b   Brumby, Anthony M ^a,b  

^a PETER MACCALLUM CANCER CENTRE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF BARCELONA   (Spain)

^d INSTITUT DE BIOLOGIA MOLECULAR DE BARCELONA   (Spain)

^e TOKYO METROPOLITAN UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ABRUPT PROTEIN; STEROID RECEPTOR COACTIVATOR 3; STRESS ACTIVATED PROTEIN KINASE; TAIMAN PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HTH; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ABRUPT GENE; ANIMAL TISSUE; ANTENNA (ORGAN); ARTICLE; CARCINOGENESIS; CELL DIFFERENTIATION; CELL FATE; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; GENE OVEREXPRESSION; HIPPO SIGNALING; LOSS OF FUNCTION MUTATION; NONHUMAN; ONCOGENE; OPTIC DISK; PROMOTER REGION; SCRIBBLED GENE; SIGNAL TRANSDUCTION; STEM CELL; TRANSCRIPTION REGULATION; TUMOR GROWTH; TUMOR OVERGROWTH;

ANIMALS; CARCINOGENESIS; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EYE NEOPLASMS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAP KINASE SIGNALING SYSTEM; NEOPLASMS, EXPERIMENTAL; NEOPLASMS, GLANDULAR AND EPITHELIAL; NUCLEAR PROTEINS; ONCOGENE PROTEIN P65(GAG-JUN); PROTEIN-SERINE-THREONINE KINASES; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

EID: 84880785143     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003627     Document Type: Article

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