메뉴 건너뛰기




Volumn 91, Issue 4, 2013, Pages 306-315

Quinidine elicits proarrhythmic changes in ventricular repolarization and refractoriness in guinea-pig

Author keywords

Electrical restitution; Proarrhythmia; Quinidine; Refractoriness; Repolarization

Indexed keywords

QUINIDINE;

EID: 84880773085     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/cjpp-2012-0379     Document Type: Article
Times cited : (18)

References (60)
  • 1
    • 1842855333 scopus 로고    scopus 로고
    • Sex differences in ventricular repolarization: From cardiac electrophysiology to torsades de pointes
    • doi:10.1111/j.1472-8206.2004.00230.x. PMID:15066127
    • Abi-Gerges, N., Philp, K., Pollard, C., Wakefield, I., Hammond, T.G., and Valentin, J.-P. 2004. Sex differences in ventricular repolarization: from cardiac electrophysiology to torsades de pointes. Fundam. Clin. Pharmacol. 18(2): 139-151. doi:10.1111/j.1472-8206.2004.00230.x. PMID:15066127.
    • (2004) Fundam. Clin. Pharmacol , vol.18 , Issue.2 , pp. 139-151
    • Abi-Gerges, N.1    Philp, K.2    Pollard, C.3    Wakefield, I.4    Hammond, T.G.5    Valentin, J.-P.6
  • 2
    • 0030667344 scopus 로고    scopus 로고
    • Effects of quinidine on repolarization in canine epicardium, midmyocardium, and endocardium. II. In vivo study
    • doi:10.1161/01.CIR.96.11.4019. PMID:9403627
    • Anyukhovsky, E.P., Sosunov, E.A., Feinmark, S.J., and Rosen, M.R. 1997. Effects of quinidine on repolarization in canine epicardium, midmyocardium, and endocardium. II. In vivo study. Circulation, 96(11): 4019-4026. doi:10.1161/01.CIR.96.11.4019. PMID:9403627.
    • (1997) Circulation , vol.96 , Issue.11 , pp. 4019-4026
    • Anyukhovsky, E.P.1    Sosunov, E.A.2    Feinmark, S.J.3    Rosen, M.R.4
  • 3
    • 0030888769 scopus 로고    scopus 로고
    • Optical mapping of drug-induced polymorphic arrhythmias and torsade de pointes in the isolated rabbit heart
    • doi:10.1016/S0735-1097(96)00588-8. PMID:9091531
    • Asano, Y., Davidenko, J.M., Baxter, W.T., Gray, R.A., and Jalife, J. 1997. Optical mapping of drug-induced polymorphic arrhythmias and torsade de pointes in the isolated rabbit heart. J. Am. Coll. Cardiol. 29(4): 831-842. doi:10.1016/S0735-1097(96)00588-8. PMID:9091531.
    • (1997) J. Am. Coll. Cardiol , vol.29 , Issue.4 , pp. 831-842
    • Asano, Y.1    Davidenko, J.M.2    Baxter, W.T.3    Gray, R.A.4    Jalife, J.5
  • 4
    • 0025860749 scopus 로고
    • Suppression of time-dependent outward current in guinea-pig ventricular myocytes. Actions of quinidine and amiodarone
    • doi:10.1161/01.RES.69.2.519. PMID:1860189
    • Balser, J.R., Bennett, P.B., Hondeghem, L.M., and Roden, D.M. 1991. Suppression of time-dependent outward current in guinea-pig ventricular myocytes. Actions of quinidine and amiodarone. Circ. Res. 69(2): 519-529. doi:10.1161/01.RES.69.2.519. PMID:1860189.
    • (1991) Circ. Res , vol.69 , Issue.2 , pp. 519-529
    • Balser, J.R.1    Bennett, P.B.2    Hondeghem, L.M.3    Roden, D.M.4
  • 5
    • 0034014806 scopus 로고    scopus 로고
    • Greater quinidine-induced QTc interval prolongation in women
    • doi:10.1067/mcp.2000.105761. PMID:10801251
    • Benton, R.E., Sale, M., Flockhart, D.A., and Woosley, R.L. 2000. Greater quinidine-induced QTc interval prolongation in women. Clin. Pharmacol. Ther. 67(4): 413-418. doi:10.1067/mcp.2000.105761. PMID:10801251.
    • (2000) Clin. Pharmacol. Ther , vol.67 , Issue.4 , pp. 413-418
    • Benton, R.E.1    Sale, M.2    Flockhart, D.A.3    Woosley, R.L.4
  • 7
    • 0032999081 scopus 로고    scopus 로고
    • + current: A potential mechanism of the proarrhythmic effects of methanesulfonanilide class III agents
    • doi:10.1016/S0008-6363(99)00061-9. PMID:10536698
    • + current: a potential mechanism of the proarrhythmic effects of methanesulfonanilide class III agents. Cardiovasc. Res. 43(1): 135-147. doi:10.1016/S0008-6363(99)00061-9. PMID:10536698.
    • (1999) Cardiovasc. Res , vol.43 , Issue.1 , pp. 135-147
    • Cheng, J.1    Kamiya, K.2    Liu, W.3    Tsuji, Y.4    Toyama, J.5    Kodama, I.6
  • 8
    • 0020059648 scopus 로고
    • Mechanisms of action of lidocaine and quinidine on action potential duration in rabbit cardiac Purkinje fibers. An effect on steady state sodium currents?
    • doi:10.1161/01.RES.50.1.17. PMID: 6274542
    • Colatsky, T.J. 1982. Mechanisms of action of lidocaine and quinidine on action potential duration in rabbit cardiac Purkinje fibers. An effect on steady state sodium currents? Circ. Res. 50(1): 17-27. doi:10.1161/01.RES.50.1.17. PMID: 6274542.
    • (1982) Circ. Res , vol.50 , Issue.1 , pp. 17-27
    • Colatsky, T.J.1
  • 9
    • 0025542167 scopus 로고
    • Efficacy and safety of quinidine therapy for maintenance of sinus rhythm after cardioversion. A meta-analysis of randomized control trials
    • doi:10.1161/01.CIR.82.4.1106. PMID:2144796
    • Coplen, S.E., Antman, E.M., Berlin, J.A., Hewitt, P., and Chalmers, T.C. 1990. Efficacy and safety of quinidine therapy for maintenance of sinus rhythm after cardioversion. A meta-analysis of randomized control trials. Circulation, 82(4): 1106-1116. doi:10.1161/01.CIR.82.4.1106. PMID:2144796.
    • (1990) Circulation , vol.82 , Issue.4 , pp. 1106-1116
    • Coplen, S.E.1    Antman, E.M.2    Berlin, J.A.3    Hewitt, P.4    Chalmers, T.C.5
  • 10
    • 0024536109 scopus 로고
    • Quinidine-induced action potential prolongation, early after depolarizations, and triggered activity in canine Purkinje fibers
    • Davidenko, J.M., Cohen, L., Goodrow, R., and Antzelevitch, C. 1989. Quinidine-induced action potential prolongation, early after depolarizations, and triggered activity in canine Purkinje fibers. Circulation, 79(3): 674-686.
    • (1989) Circulation , vol.79 , Issue.3 , pp. 674-686
    • Davidenko, J.M.1    Cohen, L.2    Goodrow, R.3    Antzelevitch, C.4
  • 11
    • 0027525943 scopus 로고
    • Comparative study on the proarrhythmic effects of some antiarrhythmic agents
    • doi:10.1161/01.CIR.87.2.617. PMID:8425305
    • Dhein, S., Muller, A., Gerwin, R., and Klaus, W. 1993. Comparative study on the proarrhythmic effects of some antiarrhythmic agents. Circulation, 87(2): 617-630. doi:10.1161/01.CIR.87.2.617. PMID:8425305.
    • (1993) Circulation , vol.87 , Issue.2 , pp. 617-630
    • Dhein, S.1    Muller, A.2    Gerwin, R.3    Klaus, W.4
  • 12
    • 0026649118 scopus 로고
    • Antiarrhythmic drug therapy and cardiac mortality in atrial fibrillation
    • doi:10.1016/0735-1097(92)90003-6. PMID:1512329
    • Flaker, G.C., Blackshear, J.L., McBride, R., Kronmal, R.A., Halperin, J.L., and Hart, R.G. 1992. Antiarrhythmic drug therapy and cardiac mortality in atrial fibrillation. J. Am. Coll. Cardiol. 20(3): 527-532. doi:10.1016/0735-1097(92)90003-6. PMID:1512329.
    • (1992) J. Am. Coll. Cardiol , vol.20 , Issue.3 , pp. 527-532
    • Flaker, G.C.1    Blackshear, J.L.2    McBride, R.3    Kronmal, R.A.4    Halperin, J.L.5    Hart, R.G.6
  • 13
    • 0023948495 scopus 로고
    • Frequency-dependent effects of quinidine on the relationship between action potential duration and refractoriness in the canine heart in situ
    • doi:10.1161/01.CIR.77.5.1177. PMID:3359594
    • Franz, M.R., and Costard, A. 1988. Frequency-dependent effects of quinidine on the relationship between action potential duration and refractoriness in the canine heart in situ. Circulation, 77(5): 1177-1184. doi:10.1161/01.CIR.77.5.1177. PMID:3359594.
    • (1988) Circulation , vol.77 , Issue.5 , pp. 1177-1184
    • Franz, M.R.1    Costard, A.2
  • 14
    • 34447250066 scopus 로고    scopus 로고
    • Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart
    • doi:10.1113/jphysiol.2006.126714. PMID:17478540
    • Gaborit, N., LeBouter, S., Szuts, V., Varro, A., Escande, D., Nattel, S., and Demolombe, S. 2007. Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart. J. Physiol. 582(2): 675-693. doi:10.1113/jphysiol.2006.126714. PMID:17478540.
    • (2007) J. Physiol , vol.582 , Issue.2 , pp. 675-693
    • Gaborit, N.1    Lebouter, S.2    Szuts, V.3    Varro, A.4    Escande, D.5    Nattel, S.6    Demolombe, S.7
  • 15
    • 0034705040 scopus 로고    scopus 로고
    • Preventing ventricular fibrillation by flattening cardiac restitution
    • doi:10.1073/pnas.090492697. PMID: 10811880
    • Garfinkel, A., Kim, Y.H., Voroshilovsky, O., Qu, Z., Kil, J.R., Lee, M.H., et al. 2000. Preventing ventricular fibrillation by flattening cardiac restitution. Proc. Natl. Acad. Sci. U.S.A. 97(11): 6061-6066. doi:10.1073/pnas.090492697. PMID: 10811880.
    • (2000) Proc. Natl. Acad. Sci. U.S.A , vol.97 , Issue.11 , pp. 6061-6066
    • Garfinkel, A.1    Kim, Y.H.2    Voroshilovsky, O.3    Qu, Z.4    Kil, J.R.5    Lee, M.H.6
  • 16
    • 53449095085 scopus 로고    scopus 로고
    • Dynamic mechanism for initiation of ventricular fibrillation in vivo
    • doi:10.1161/CIRCULATIONAHA.107.738013. PMID: 18725487
    • Gelzer, A.R., Koller, M.L., Otani, N.F., Fox, J.J., Enyeart, M.W., Hooker, G.J., et al. 2008. Dynamic mechanism for initiation of ventricular fibrillation in vivo. Circulation, 118(11): 1123-1129. doi:10.1161/CIRCULATIONAHA.107.738013. PMID: 18725487.
    • (2008) Circulation , vol.118 , Issue.11 , pp. 1123-1129
    • Gelzer, A.R.1    Koller, M.L.2    Otani, N.F.3    Fox, J.J.4    Enyeart, M.W.5    Hooker, G.J.6
  • 17
    • 9344265214 scopus 로고    scopus 로고
    • Chronic beta-adrenoreceptor activation increases cardiac cavity size through chamber remodeling and not via modifications in myocardial material properties
    • doi:10.1152/ajpheart.00501.2004. PMID:15319203
    • Gibbs, M., Veliotes, D.G., Anamourlis, C., Badenhorst, D., Osadchii, O.E., Norton, G.R., and Woodiwiss, A.J. 2004. Chronic beta-adrenoreceptor activation increases cardiac cavity size through chamber remodeling and not via modifications in myocardial material properties. Am. J. Physiol. Heart Circ. Physiol. 287(6): H2762-H2767. doi:10.1152/ajpheart.00501.2004. PMID:15319203.
    • (2004) Am. J. Physiol. Heart Circ. Physiol , vol.287 , Issue.6
    • Gibbs, M.1    Veliotes, D.G.2    Anamourlis, C.3    Badenhorst, D.4    Osadchii, O.E.5    Norton, G.R.6    Woodiwiss, A.J.7
  • 18
    • 0026355245 scopus 로고
    • Propafenone-induced torsade de pointes: Cross-reactivity with quinidine. Pacing Clin
    • doi:10.1111/j.1540-8159.1991.tb02729.x. PMID: 1721143
    • Hii, J.T., Wyse, D.G., Gillis, A.M., Cohen, J.M, and Mitchell, L.B. 1991. Propafenone-induced torsade de pointes: cross-reactivity with quinidine. Pacing Clin. Electrophysiol. 14(11): 1568-1570. doi:10.1111/j.1540-8159.1991.tb02729.x. PMID: 1721143.
    • (1991) Electrophysiol , vol.14 , Issue.11 , pp. 1568-1570
    • Hii, J.T.1    Wyse, D.G.2    Gillis, A.M.3    Cohen, J.M.4    Mitchell, L.B.5
  • 19
    • 0022966619 scopus 로고
    • Effects of quinidine on plateau currents of guinea-pig ventricular myocytes
    • doi:10.1016/S0022-2828(86)80296-6. PMID:3783725
    • Hiraoka, M., Sawada, K., and Kawano, S. 1986. Effects of quinidine on plateau currents of guinea-pig ventricular myocytes. J. Mol. Cell. Cardiol. 18(10): 1097-1106. doi:10.1016/S0022-2828(86)80296-6. PMID:3783725.
    • (1986) J. Mol. Cell. Cardiol , vol.18 , Issue.10 , pp. 1097-1106
    • Hiraoka, M.1    Sawada, K.2    Kawano, S.3
  • 20
    • 0028792378 scopus 로고
    • Efficacy and proarrhythmic hazards of pharmacologic cardioversion of atrial fibrillation: Prospective comparison of sotalol versus quinidine
    • doi:10.1016/0735-1097(95)00286-5. PMID:7560608
    • Hohnloser, S.H., van deLoo, A., and Baedeker, F. 1995. Efficacy and proarrhythmic hazards of pharmacologic cardioversion of atrial fibrillation: prospective comparison of sotalol versus quinidine. J. Am. Coll. Cardiol. 26(4): 852-858. doi:10.1016/0735-1097(95)00286-5. PMID:7560608.
    • (1995) J. Am. Coll. Cardiol , vol.26 , Issue.4 , pp. 852-858
    • Hohnloser, S.H.1    van de Loo, A.2    Baedeker, F.3
  • 21
    • 0035901578 scopus 로고    scopus 로고
    • Instability and triangulation of the action potential predict serious arrhythmia, but APD prolongation is antiarrhythmic
    • doi:10.1161/01.CIR.103.15. 2004. PMID:11306531
    • Hondeghem, L., Carlsson, L., and Duker, G. 2001. Instability and triangulation of the action potential predict serious arrhythmia, but APD prolongation is antiarrhythmic. Circulation, 103(15): 2004-2013. doi:10.1161/01.CIR.103.15. 2004. PMID:11306531.
    • (2001) Circulation , vol.103 , Issue.15 , pp. 2004-2013
    • Hondeghem, L.1    Carlsson, L.2    Duker, G.3
  • 22
    • 0023611290 scopus 로고
    • Quinidine-induced inhibition of transient outward current in cardiac muscle
    • PMID:2443024
    • Imaizumi, Y., and Giles, W.R. 1987. Quinidine-induced inhibition of transient outward current in cardiac muscle. Am. J. Physiol. Heart Circ. Physiol. 253(22): H704-H708. PMID:2443024.
    • (1987) Am. J. Physiol. Heart Circ. Physiol , vol.253 , Issue.22
    • Imaizumi, Y.1    Giles, W.R.2
  • 23
    • 0003633755 scopus 로고    scopus 로고
    • Institute of Laboratory Animal Resources, National Academy Press, Washington, D.C
    • Institute of Laboratory Animal Resources. 1996. Guide for the care and use of laboratory animals. National Academy Press, Washington, D.C.
    • (1996) Guide For the Care and Use of Laboratory Animals
  • 24
    • 2342624602 scopus 로고    scopus 로고
    • Gender-related differences in ventricular myocyte repolarization in the guinea-pig
    • doi:10.1007/s00395-003-0451-6. PMID:15088103
    • James, A.F., Arberry, L.A., and Hancox, J.C. 2004. Gender-related differences in ventricular myocyte repolarization in the guinea-pig. Basic Res. Cardiol. 99(3): 183-192. doi:10.1007/s00395-003-0451-6. PMID:15088103.
    • (2004) Basic Res. Cardiol , vol.99 , Issue.3 , pp. 183-192
    • James, A.F.1    Arberry, L.A.2    Hancox, J.C.3
  • 25
    • 0027186122 scopus 로고
    • Rate-dependent prolongation of cardiac action potentials by a methanesulfonanilide class III antiarrhythmic agent. Circ
    • doi:10.1161/01.RES.72.1.75. PMID:8417848
    • Jurkiewicz, N.K., and Sanguinetti, M.C. 1993. Rate-dependent prolongation of cardiac action potentials by a methanesulfonanilide class III antiarrhythmic agent. Circ. Res. 72(1): 75-83. doi:10.1161/01.RES.72.1.75. PMID:8417848.
    • (1993) Res , vol.72 , Issue.1 , pp. 75-83
    • Jurkiewicz, N.K.1    Sanguinetti, M.C.2
  • 26
    • 0029839950 scopus 로고    scopus 로고
    • Modulation of ventricular repolarization by a premature stimulus. Role of epicardial dispersion of repolarization kinetics demonstrated by optical mapping of the intact guinea-pig heart
    • doi:10.1161/01.RES.79.3.493. PMID: 8781480
    • Laurita, K.R., Girouard, S.D., and Rosenbaum, D.S. 1996. Modulation of ventricular repolarization by a premature stimulus. Role of epicardial dispersion of repolarization kinetics demonstrated by optical mapping of the intact guinea-pig heart. Circ. Res. 79(3): 493-503. doi:10.1161/01.RES.79.3.493. PMID: 8781480.
    • (1996) Circ. Res , vol.79 , Issue.3 , pp. 493-503
    • Laurita, K.R.1    Girouard, S.D.2    Rosenbaum, D.S.3
  • 27
    • 0026526791 scopus 로고
    • Relation between repolarization and refractoriness in the human ventricle: Cycle length dependence and effect of procainamide
    • doi:10.1016/S0735-1097(10)80281-5. PMID:1538018
    • Lee, R.J., Liem, L.B., Cohen, T.J., and Franz, M.R. 1992. Relation between repolarization and refractoriness in the human ventricle: cycle length dependence and effect of procainamide. J. Am. Coll. Cardiol. 19(3): 614-618. doi:10.1016/S0735-1097(10)80281-5. PMID:1538018.
    • (1992) J. Am. Coll. Cardiol , vol.19 , Issue.3 , pp. 614-618
    • Lee, R.J.1    Liem, L.B.2    Cohen, T.J.3    Franz, M.R.4
  • 28
    • 0035863689 scopus 로고    scopus 로고
    • QT dispersion, T-wave projection, and heterogeneity of repolarization in patients with coronary artery disease
    • doi:10.1016/S0002-9149(00)01306-0. PMID:11152829
    • Lee, K.W., Kligfield, P., Dower, G.E., and Okin, P.M. 2001. QT dispersion, T-wave projection, and heterogeneity of repolarization in patients with coronary artery disease. Am. J. Cardiol. 87(2): 148-151. doi:10.1016/S0002-9149(00)01306-0. PMID:11152829.
    • (2001) Am. J. Cardiol , vol.87 , Issue.2 , pp. 148-151
    • Lee, K.W.1    Kligfield, P.2    Dower, G.E.3    Okin, P.M.4
  • 29
    • 0030588699 scopus 로고    scopus 로고
    • Sex difference in risk of torsade de pointes with d,l-sotalol
    • doi:10.1161/01.CIR.94.10.2535. PMID:8921798
    • Lehmann, M.H., Hardy, S., Archibald, D., Quart, B., and MacNeil, D.J. 1996. Sex difference in risk of torsade de pointes with d,l-sotalol. Circulation, 94(10): 2535-2541. doi:10.1161/01.CIR.94.10.2535. PMID:8921798.
    • (1996) Circulation , vol.94 , Issue.10 , pp. 2535-2541
    • Lehmann, M.H.1    Hardy, S.2    Archibald, D.3    Quart, B.4    Macneil, D.J.5
  • 30
    • 0033840650 scopus 로고    scopus 로고
    • QT dispersion does not represent electrocardiographic interlead heterogeneity of ventricular repolarization
    • doi:10.1111/j.1540-8167.2000.tb00061.x. PMID:10969744
    • Malik, M., Acar, B., Gang, Y., Yap, Y.G., Hnatkova, K., and Camm, A.J. 2000. QT dispersion does not represent electrocardiographic interlead heterogeneity of ventricular repolarization. J. Cardiovasc. Electrophysiol. 11(8): 835-843. doi:10.1111/j.1540-8167.2000.tb00061.x. PMID:10969744.
    • (2000) J. Cardiovasc. Electrophysiol , vol.11 , Issue.8 , pp. 835-843
    • Malik, M.1    Acar, B.2    Gang, Y.3    Yap, Y.G.4    Hnatkova, K.5    Camm, A.J.6
  • 31
    • 34249090724 scopus 로고    scopus 로고
    • Reduction of dispersion of repolarization and prolongation of postrepolarization refractoriness explain the antiarrhythmic effects of quinidine in a model of short QT syndrome
    • doi:10.1111/j.1540-8167.2007.00813.x. PMID:17521304
    • Milberg, P., Tegelkamp, R., Osada, N., Schimpf, R., Wolpert, C., Breithardt, G., et al. 2007. Reduction of dispersion of repolarization and prolongation of postrepolarization refractoriness explain the antiarrhythmic effects of quinidine in a model of short QT syndrome. J. Cardiovasc. Electrophysiol. 18(6): 658-664. doi:10.1111/j.1540-8167.2007.00813.x. PMID:17521304.
    • (2007) J. Cardiovasc. Electrophysiol , vol.18 , Issue.6 , pp. 658-664
    • Milberg, P.1    Tegelkamp, R.2    Osada, N.3    Schimpf, R.4    Wolpert, C.5    Breithardt, G.6
  • 32
    • 0001392789 scopus 로고    scopus 로고
    • Potassium channel down-regulation in heart failure. Cardiovasc
    • doi:10.1016/S0008-6363(97)00274-5. PMID:9614489
    • Nabauer, M., and Kaab, S. 1998. Potassium channel down-regulation in heart failure. Cardiovasc. Res. 37(2): 324-334. doi:10.1016/S0008-6363(97)00274-5. PMID:9614489.
    • (1998) Res , vol.37 , Issue.2 , pp. 324-334
    • Nabauer, M.1    Kaab, S.2
  • 33
    • 84876412086 scopus 로고    scopus 로고
    • Dofetilide promotes repolarization abnormalities in perfused guinea-pig heart
    • doi:10.1007/s10557-012-6405-1. PMID:22918600
    • Osadchii, O.E. 2012a. Dofetilide promotes repolarization abnormalities in perfused guinea-pig heart. Cardiovasc. Drugs Ther. 26(6): 489-500. doi:10.1007/s10557-012-6405-1. PMID:22918600.
    • (2012) Cardiovasc. Drugs Ther , vol.26 , Issue.6 , pp. 489-500
    • Osadchii, O.E.1
  • 34
    • 84870054773 scopus 로고    scopus 로고
    • Flecainide-induced proarrhythmia is attributed to abnormal changes in repolarization and refractoriness in perfused guinea-pig heart
    • doi:10.1097/FJC.0b013e31826b86cf. PMID:22932706
    • Osadchii, O.E. 2012b. Flecainide-induced proarrhythmia is attributed to abnormal changes in repolarization and refractoriness in perfused guinea-pig heart. J. Cardiovasc. Pharmacol. 60(5): 456-466. doi:10.1097/FJC.0b013e31826b86cf. PMID:22932706.
    • (2012) J. Cardiovasc. Pharmacol , vol.60 , Issue.5 , pp. 456-466
    • Osadchii, O.E.1
  • 35
    • 70350761979 scopus 로고    scopus 로고
    • Electrophysiological determinants of hypokalemia-induced arrhythmogenicity in the guinea-pig heart
    • doi:10.1111/j.1748-1716.2009.02028.x. PMID:19656123
    • Osadchii, O.E., and Olesen, S.P. 2009. Electrophysiological determinants of hypokalemia-induced arrhythmogenicity in the guinea-pig heart. Acta Physiol. (Oxf.), 197(4): 273-287. doi:10.1111/j.1748-1716.2009.02028.x. PMID:19656123.
    • (2009) Acta Physiol (Oxf.) , vol.197 , Issue.4 , pp. 273-287
    • Osadchii, O.E.1    Olesen, S.P.2
  • 36
    • 27744536658 scopus 로고    scopus 로고
    • Mechanisms of preserved baseline cardiac systolic function in rats with adrenergic inotropic downregulation
    • doi:10.1016/j.lfs.2005.04.047. PMID: 16137710
    • Osadchii, O., Woodiwiss, A., Alves, N., and Norton, G. 2005. Mechanisms of preserved baseline cardiac systolic function in rats with adrenergic inotropic downregulation. Life Sci. 78(4): 366-375. doi:10.1016/j.lfs.2005.04.047. PMID: 16137710.
    • (2005) Life Sci , vol.78 , Issue.4 , pp. 366-375
    • Osadchii, O.1    Woodiwiss, A.2    Alves, N.3    Norton, G.4
  • 37
    • 34047112435 scopus 로고    scopus 로고
    • Rat strainrelated differences in myocardial adrenergic tone and the impact on cardiac fibrosis, adrenergic responsiveness and myocardial structure and function. Pharmacol
    • doi:10.1016/j.phrs.2006.12.005. PMID:17257851
    • Osadchii, O., Norton, G., Deftereos, D., and Woodiwiss, A. 2007. Rat strainrelated differences in myocardial adrenergic tone and the impact on cardiac fibrosis, adrenergic responsiveness and myocardial structure and function. Pharmacol. Res. 55(4): 287-294. doi:10.1016/j.phrs.2006.12.005. PMID:17257851.
    • (2007) Res , vol.55 , Issue.4 , pp. 287-294
    • Osadchii, O.1    Norton, G.2    Deftereos, D.3    Woodiwiss, A.4
  • 38
    • 73549103079 scopus 로고    scopus 로고
    • Predictive value of electrical restitution in hypokalemia-induced ventricular arrhythmogenicity
    • doi:10.1152/ajpheart.00695. 2009. PMID:19897712
    • Osadchii, O.E., Larsen, A.P., and Olesen, S.P. 2010. Predictive value of electrical restitution in hypokalemia-induced ventricular arrhythmogenicity. Am. J. Physiol. Heart Circ. Physiol. 298(1): H210-H220. doi:10.1152/ajpheart.00695. 2009. PMID:19897712.
    • (2010) Am. J. Physiol. Heart Circ. Physiol , vol.298 , Issue.1
    • Osadchii, O.E.1    Larsen, A.P.2    Olesen, S.P.3
  • 39
    • 79955065665 scopus 로고    scopus 로고
    • + channel distribution and electrophysiological heterogeneities in guinea-pig ventricular wall
    • doi:10.1152/ajpheart.00816. 2010. PMID:21186271
    • + channel distribution and electrophysiological heterogeneities in guinea-pig ventricular wall. Am. J. Physiol. Heart Circ. Physiol. 300(3): H989-H1002. doi:10.1152/ajpheart.00816. 2010. PMID:21186271.
    • (2011) Am. J. Physiol. Heart Circ. Physiol , vol.300 , Issue.3
    • Osadchii, O.E.1    Soltysinska, E.2    Olesen, S.P.3
  • 40
    • 0030591729 scopus 로고    scopus 로고
    • Proarrhythmia during drug treatment of supraventricular tachycardia: Paradoxical risk of sinus rhythm for sudden death
    • doi:10.1016/S0002-9149(96)00564-4. PMID:8903274
    • Prystowsky, E.N. 1996. Proarrhythmia during drug treatment of supraventricular tachycardia: paradoxical risk of sinus rhythm for sudden death. Am. J. Cardiol. 78(Suppl. 8A): 35-41. doi:10.1016/S0002-9149(96)00564-4. PMID:8903274.
    • (1996) Am. J. Cardiol , vol.78 , Issue.SUPPL. 8A , pp. 35-41
    • Prystowsky, E.N.1
  • 41
    • 0029822088 scopus 로고    scopus 로고
    • Ionic mechanisms for prolongation of refractoriness and their proarrhythmic and antiarrhythmic correlates
    • doi:10.1016/S0002-9149(96)00448-1. PMID:8780324
    • Roden, D.M. 1996. Ionic mechanisms for prolongation of refractoriness and their proarrhythmic and antiarrhythmic correlates. Am. J. Cardiol. 78(Suppl. 4A): 12-16. doi:10.1016/S0002-9149(96)00448-1. PMID:8780324.
    • (1996) Am. J. Cardiol , vol.78 , Issue.SUPPL. 4A , pp. 12-16
    • Roden, D.M.1
  • 42
    • 0023819691 scopus 로고
    • K activation in guinea-pig ventricular myocytes
    • doi:10.1161/01.RES.62.5.1055. PMID:2452034
    • Roden, D.M., Bennett, P.B., Snyders, D.J., Balser, J.R., and Hondeghem, LM. 1988. Quinidine delays IK activation in guinea-pig ventricular myocytes. Circ. Res. 62(5): 1055-1058. doi:10.1161/01.RES.62.5.1055. PMID:2452034.
    • (1988) Circ. Res , vol.62 , Issue.5 , pp. 1055-1058
    • Roden, D.M.1    Bennett, P.B.2    Snyders, D.J.3    Balser, J.R.4    Hondeghem, L.M.5
  • 43
    • 0021972633 scopus 로고
    • Action potential prolongation and induction of abnormal automaticity by low quinidine concentrations in canine Purkinje fibers
    • Roden, D.M., and Hoffman, B.F. 1985. Action potential prolongation and induction of abnormal automaticity by low quinidine concentrations in canine Purkinje fibers. Circ. Res. 56(6): 857-867.
    • (1985) Circ. Res , vol.56 , Issue.6 , pp. 857-867
    • Roden, D.M.1    Hoffman, B.F.2
  • 44
    • 34047130207 scopus 로고    scopus 로고
    • The contribution of refractoriness to arrhythmic substrate in hypokalemic Langendorff-perfused murine hearts
    • doi:10.1007/s00424-007-0217-3. PMID:17295037
    • Sabir, I.N., Fraser, J.A., Killeen, M.J., Grace, A.A., and Huang, C.L. 2007. The contribution of refractoriness to arrhythmic substrate in hypokalemic Langendorff-perfused murine hearts. Pflugers Arch. 454(2): 209-222. doi:10.1007/s00424-007-0217-3. PMID:17295037.
    • (2007) Pflugers Arch , vol.454 , Issue.2 , pp. 209-222
    • Sabir, I.N.1    Fraser, J.A.2    Killeen, M.J.3    Grace, A.A.4    Huang, C.L.5
  • 47
    • 21344463329 scopus 로고    scopus 로고
    • Refining detection of drug-induced proarrhythmia: QT interval and TRIaD
    • doi:10.1016/j.hrthm.2005.03.023. PMID:15992736
    • Shah, R.R., and Hondeghem, L.M. 2005. Refining detection of drug-induced proarrhythmia: QT interval and TRIaD. Heart Rhythm, 2(7): 758-772. doi:10.1016/j.hrthm.2005.03.023. PMID:15992736.
    • (2005) Heart Rhythm , vol.2 , Issue.7 , pp. 758-772
    • Shah, R.R.1    Hondeghem, L.M.2
  • 48
    • 0028325440 scopus 로고
    • + channel blocking actions of flecainide compared with those of propafenone and quinidine in adult rat ventricular myocytes
    • PMID:8169853
    • + channel blocking actions of flecainide compared with those of propafenone and quinidine in adult rat ventricular myocytes. J. Pharmacol. Exp. Ther. 269(1): 66-74. PMID:8169853.
    • (1994) J. Pharmacol. Exp. Ther , vol.269 , Issue.1 , pp. 66-74
    • Slawsky, M.T.1    Castle, N.A.2
  • 49
    • 79959378055 scopus 로고    scopus 로고
    • Myocardial structural, contractile and electrophysiological changes in the guinea-pig heart failure model induced by chronic sympathetic activation
    • doi:10.1113/expphysiol.2011.058503. PMID:21571815
    • Soltysinska, E., Olesen, S.P., and Osadchii, O.E. 2011. Myocardial structural, contractile and electrophysiological changes in the guinea-pig heart failure model induced by chronic sympathetic activation. Exp. Physiol. 96(7): 647-663. doi:10.1113/expphysiol.2011.058503. PMID:21571815.
    • (2011) Exp. Physiol , vol.96 , Issue.7 , pp. 647-663
    • Soltysinska, E.1    Olesen, S.P.2    Osadchii, O.E.3
  • 50
    • 0030707554 scopus 로고    scopus 로고
    • Effects of quinidine on repolarization in canine epicardium, midmyocardium, and endocardium. I
    • doi:10.1161/01.CIR.96.11.4011. PMID:9403626
    • Sosunov, E.A., Anyukhovsky, E.P., and Rosen, M.R. 1997. Effects of quinidine on repolarization in canine epicardium, midmyocardium, and endocardium. I. In vitro study. Circulation, 96(11): 4011-4018. doi:10.1161/01.CIR.96.11.4011. PMID:9403626.
    • (1997) Vitro Study. Circulation , vol.96 , Issue.11 , pp. 4011-4018
    • Sosunov, E.A.1    Anyukhovsky, E.P.2    Rosen, M.R.3
  • 51
    • 33750857066 scopus 로고    scopus 로고
    • Modulation of quinidine-induced arrhythmias by temperature in perfused rabbit heart
    • PMID:9530193
    • Spear, J.F., and Moore, E.N. 1998. Modulation of quinidine-induced arrhythmias by temperature in perfused rabbit heart. Am. J. Physiol. 274(3): H817-H828. PMID:9530193.
    • (1998) Am. J. Physiol , vol.274 , Issue.3
    • Spear, J.F.1    Moore, E.N.2
  • 52
    • 0024359502 scopus 로고
    • Electrophysiologic substrate of torsade de pointes: Dispersion of repolarization or early afterdepolarizations
    • doi:10.1016/0735-1097(89)90069-7. PMID:2661626
    • Surawicz, B. 1989. Electrophysiologic substrate of torsade de pointes: dispersion of repolarization or early afterdepolarizations? J. Am. Coll. Cardiol. 14(1): 172-184. doi:10.1016/0735-1097(89)90069-7. PMID:2661626.
    • (1989) J. Am. Coll. Cardiol , vol.14 , Issue.1 , pp. 172-184
    • Surawicz, B.1
  • 53
    • 0033151558 scopus 로고    scopus 로고
    • Chaos and the transition to ventricular fibrillation. A new approach to antiarrhythmic drug evaluation
    • doi:10.1161/01.CIR.99.21.2819. PMID:10351978
    • Weiss, J.N., Garfinkel, A., Karaguezian, H.S., Qu, Z., and Chen, P.S. 1999. Chaos and the transition to ventricular fibrillation. A new approach to antiarrhythmic drug evaluation. Circulation, 99(21): 2819-2826. doi:10.1161/01.CIR.99.21.2819. PMID:10351978.
    • (1999) Circulation , vol.99 , Issue.21 , pp. 2819-2826
    • Weiss, J.N.1    Garfinkel, A.2    Karaguezian, H.S.3    Qu, Z.4    Chen, P.S.5
  • 54
    • 0035017747 scopus 로고    scopus 로고
    • Electrophysiological heterogeneity and stability of re-entry in simulated cardiac tissue
    • PMID:11158949
    • Xie, F., Qu, Z., Garfinkel, A., and Weiss, J.N. 2001. Electrophysiological heterogeneity and stability of re-entry in simulated cardiac tissue. Am. J. Physiol. Heart Circ. Physiol. 280(2): H535-H545. PMID:11158949.
    • (2001) Am. J. Physiol. Heart Circ. Physiol , vol.280 , Issue.2
    • Xie, F.1    Qu, Z.2    Garfinkel, A.3    Weiss, J.N.4
  • 55
    • 0030022457 scopus 로고    scopus 로고
    • Extracellular potassium modulation of drug block of IKr
    • doi:10.1161/01.CIR.93.3.407. PMID: 8565156
    • Yang, T., and Roden, D.M. 1996. Extracellular potassium modulation of drug block of IKr. Circulation, 93(3): 407-411. doi:10.1161/01.CIR.93.3.407. PMID: 8565156.
    • (1996) Circulation , vol.93 , Issue.3 , pp. 407-411
    • Yang, T.1    Roden, D.M.2
  • 56
    • 0034774943 scopus 로고    scopus 로고
    • Drug block of IKr: Model systems and relevance to human arrhythmias
    • doi:10.1097/00005344-200111000-00010. PMID:11602820
    • Yang, T., Snyders, D., and Roden, D.M. 2001. Drug block of IKr: model systems and relevance to human arrhythmias. J. Cardiovasc. Pharmacol. 38(5): 737-744. doi:10.1097/00005344-200111000-00010. PMID:11602820.
    • (2001) J. Cardiovasc. Pharmacol , vol.38 , Issue.5 , pp. 737-744
    • Yang, T.1    Snyders, D.2    Roden, D.M.3
  • 57
    • 0030671179 scopus 로고    scopus 로고
    • Differential effects of D-sotalol, quinidine, and amiodarone on dispersion of ventricular repolarization in the isolated rabbit heart
    • doi:10.1111/j.1540-8167.1997.tb01014.x. PMID: 9395166
    • Zabel, M., Hohnloser, S.H., Behrens, S., Woosley, R.L., and Franz, M.R. 1997. Differential effects of D-sotalol, quinidine, and amiodarone on dispersion of ventricular repolarization in the isolated rabbit heart. J. Cardiovasc. Electrophysiol. 8(11): 1239-1245. doi:10.1111/j.1540-8167.1997.tb01014.x. PMID: 9395166.
    • (1997) J. Cardiovasc. Electrophysiol , vol.8 , Issue.11 , pp. 1239-1245
    • Zabel, M.1    Hohnloser, S.H.2    Behrens, S.3    Woosley, R.L.4    Franz, M.R.5
  • 58
    • 0029024749 scopus 로고
    • + current in ventricular myocytes of the guinea-pig type. Theoretical formulation and their role in repolarization
    • doi:10.1161/01.RES.77.1.140. PMID:7788872
    • + current in ventricular myocytes of the guinea-pig type. Theoretical formulation and their role in repolarization. Circ. Res. 77(1): 140-152. doi:10.1161/01.RES.77.1.140. PMID:7788872.
    • (1995) Circ. Res , vol.77 , Issue.1 , pp. 140-152
    • Zeng, J.1    Laurita, K.R.2    Rosenbaum, D.S.3    Rudy, Y.4
  • 60
    • 0028357213 scopus 로고
    • + channel blockade: Multiple rest states revealed by channel interactions with disopyramide and quinidine
    • PMID: 8203599
    • + channel blockade: multiple rest states revealed by channel interactions with disopyramide and quinidine. Am. J. Physiol. Heart Circ. Physiol. 266(5): H2007-H2017. PMID: 8203599.
    • (1994) Am. J. Physiol. Heart Circ. Physiol , vol.266 , Issue.5
    • Zilberter, Y.I.1    Starmer, C.F.2    Grant, A.O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.