Synergistic enhancement of antitumor effect of β-Lapachone by photodynamic induction of quinone oxidoreductase (NQO1)

Phytomedicine

Volumn 20, Issue 11, 2013, Pages 1007-1012

  Lamberti, María Julia ^a   Rumie Vittar, Natalia Belén ^a   De Carvalho Da Silva, Fernando ^b   Ferreira, Vitor Francisco ^b   Rivarola, Viviana Alicia ^a  

^a DEPARTAMENTO DE QUÍMICA   (Argentina)

^b FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

Author keywords

Lapachone; Isobologram; MCF 7c3 cells; NQO1; Photodynamic therapy; Synergy

Indexed keywords

BETA LAPACHONE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL; DRUG CYTOTOXICITY; DRUG EFFECT; HUMAN; HUMAN CELL; PHOTOCHEMOTHERAPY; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING;

Β-LAPACHONE; ANTIOXIDANT RESPONSE ELEMENT; ARE; CI; COMBINATION INDEX; DOSE REDUCTION INDEX; DRI; HEME OXYGENASE 1; HO-1; ISOBOLOGRAM; MCF-7C3 CELLS; ME-ALA; METHYL AMINOLEVULINATE ACID; NAD(P)H:QUINONE OXIDOREDUCTASE 1; NQO1; NRF2; NUCLEAR FACTOR E2-RELATED FACTOR 2; PDT; PHOTODYNAMIC THERAPY; PHOTOSENSITIZER; PPIX; PROTOPORPHYRIN IX; PS; REACTIVE OXYGEN SPECIES; ROS; SYNERGY;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BREAST NEOPLASMS; FEMALE; HUMANS; LIGHT; MCF-7 CELLS; NAD(P)H DEHYDROGENASE (QUINONE); NAPHTHOQUINONES; PHOTOCHEMOTHERAPY; PHYTOTHERAPY; PLANT EXTRACTS; REACTIVE OXYGEN SPECIES; TABEBUIA; UP-REGULATION;

EID: 84880771983     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2013.04.018     Document Type: Article

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