PCR-Induced Transitions Are the Major Source of Error in Cleaned Ultra-Deep Pyrosequencing Data

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Brodin, Johanna ^a   Mild, Mattias ^a,b   Hedskog, Charlotte ^a   Sherwood, Ellen ^c   Leitner, Thomas ^d   Andersson, Björn ^a   Albert, Jan ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b SWEDISH INSTITUTE FOR INFECTIOUS DISEASE CONTROL   (Sweden)

^c SCIENCE FOR LIFE LABORATORY   (Sweden)

^d LOS ALAMOS NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTICAL PARAMETERS; ARTICLE; CORRELATION ANALYSIS; ERROR; GENE DELETION; GENE INSERTION; GENETIC PROCEDURES; HUMAN IMMUNODEFICIENCY VIRUS 1; LIMIT OF DETECTION; NEXT GENERATION SEQUENCING; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; POLYMERASE CHAIN REACTION; PYROSEQUENCING; STRUCTURAL GENE; ULTRA DEEP PYROSEQUENCING; VIRAL GENETICS;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ANIMALS; BRAIN MAPPING; CASE-CONTROL STUDIES; CELL PHYSIOLOGICAL PHENOMENA; FEMALE; FLUORODEOXYGLUCOSE F18; FOLLOW-UP STUDIES; GLUCOSE; HUMANS; LONGITUDINAL STUDIES; MALE; MICE; MIDDLE AGED; MILD COGNITIVE IMPAIRMENT; NEURAL NETWORKS (COMPUTER); NEUROIMAGING; POSITRON-EMISSION TOMOGRAPHY; RATS;

EID: 84880760001     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0070388     Document Type: Article

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