-
1
-
-
3943054839
-
The Sir2 family of protein deacetylases
-
Blander G., Guarente L. The Sir2 family of protein deacetylases. Annu. Rev. Biochem. 2004, 73:417-435.
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 417-435
-
-
Blander, G.1
Guarente, L.2
-
2
-
-
9744244982
-
Zinc hydrolases: the mechanisms of zinc-dependent deacetylases
-
Hernick M., Fierke C.A. Zinc hydrolases: the mechanisms of zinc-dependent deacetylases. Arch. Biochem. Biophys. 2005, 433:71-84.
-
(2005)
Arch. Biochem. Biophys.
, vol.433
, pp. 71-84
-
-
Hernick, M.1
Fierke, C.A.2
-
3
-
-
10644277123
-
Structure and chemistry of the Sir2 family of NAD+-dependent histone/protein deactylases
-
Marmorstein R. Structure and chemistry of the Sir2 family of NAD+-dependent histone/protein deactylases. Biochem. Soc. Trans. 2004, 32:904-909.
-
(2004)
Biochem. Soc. Trans.
, vol.32
, pp. 904-909
-
-
Marmorstein, R.1
-
4
-
-
4944245398
-
Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin
-
Vaquero A., Scher M., Lee D., Erdjument-Bromage H., Tempst P., Reinberg D. Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. Mol. Cell 2004, 16:93-105.
-
(2004)
Mol. Cell
, vol.16
, pp. 93-105
-
-
Vaquero, A.1
Scher, M.2
Lee, D.3
Erdjument-Bromage, H.4
Tempst, P.5
Reinberg, D.6
-
5
-
-
0032977614
-
Characterization of a human gene with sequence homology to Saccharomyces cerevisiae SIR2
-
Afshar G., Murnane J.P. Characterization of a human gene with sequence homology to Saccharomyces cerevisiae SIR2. Gene 1999, 234:161-168.
-
(1999)
Gene
, vol.234
, pp. 161-168
-
-
Afshar, G.1
Murnane, J.P.2
-
6
-
-
0037291214
-
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
-
North B.J., Marshall B.L., Borra M.T., Denu J.M., Verdin E. The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase. Mol. Cell 2003, 11:437-444.
-
(2003)
Mol. Cell
, vol.11
, pp. 437-444
-
-
North, B.J.1
Marshall, B.L.2
Borra, M.T.3
Denu, J.M.4
Verdin, E.5
-
7
-
-
33846930889
-
Microtubule deacetylases, SirT2 and HDAC6, in the nervous system
-
Southwood C.M., Peppi M., Dryden S., Tainsky M.A., Gow A. Microtubule deacetylases, SirT2 and HDAC6, in the nervous system. Neurochem. Res. 2007, 32:187-195.
-
(2007)
Neurochem. Res.
, vol.32
, pp. 187-195
-
-
Southwood, C.M.1
Peppi, M.2
Dryden, S.3
Tainsky, M.A.4
Gow, A.5
-
8
-
-
84863033018
-
HDAC6 and SIRT2 promote bladder cancer cell migration and invasion by targeting cortactin
-
Zuo Q., Wu W., Li X., Zhao L., Chen W. HDAC6 and SIRT2 promote bladder cancer cell migration and invasion by targeting cortactin. Oncol. Rep. 2012, 27:819-824.
-
(2012)
Oncol. Rep.
, vol.27
, pp. 819-824
-
-
Zuo, Q.1
Wu, W.2
Li, X.3
Zhao, L.4
Chen, W.5
-
9
-
-
34547920351
-
Mutations in SIRT2 deacetylase which regulate enzymatic activity but not its interaction with HDAC6 and tubulin
-
Nahhas F., Dryden S.C., Abrams J., Tainsky M.A. Mutations in SIRT2 deacetylase which regulate enzymatic activity but not its interaction with HDAC6 and tubulin. Mol. Cell. Biochem. 2007, 303:221-230.
-
(2007)
Mol. Cell. Biochem.
, vol.303
, pp. 221-230
-
-
Nahhas, F.1
Dryden, S.C.2
Abrams, J.3
Tainsky, M.A.4
-
10
-
-
84858795617
-
Deacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradation
-
Wang F., Chan C.H., Chen K., Guan X., Lin H.K., Tong Q. Deacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradation. Oncogene 2012, 31:1546-1557.
-
(2012)
Oncogene
, vol.31
, pp. 1546-1557
-
-
Wang, F.1
Chan, C.H.2
Chen, K.3
Guan, X.4
Lin, H.K.5
Tong, Q.6
-
11
-
-
34547397081
-
SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation
-
Jing E., Gesta S., Kahn C.R. SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation. Cell Metab. 2007, 6:105-114.
-
(2007)
Cell Metab.
, vol.6
, pp. 105-114
-
-
Jing, E.1
Gesta, S.2
Kahn, C.R.3
-
12
-
-
78649738291
-
SIRT2 regulates NF-kappaB dependent gene expression through deacetylation of p65 Lys310
-
Rothgiesser K.M., Erener S., Waibel S., Luscher B., Hottiger M.O. SIRT2 regulates NF-kappaB dependent gene expression through deacetylation of p65 Lys310. J. Cell Sci. 2010, 123:4251-4258.
-
(2010)
J. Cell Sci.
, vol.123
, pp. 4251-4258
-
-
Rothgiesser, K.M.1
Erener, S.2
Waibel, S.3
Luscher, B.4
Hottiger, M.O.5
-
13
-
-
77149172855
-
SIRT2-mediated protein deacetylation: an emerging key regulator in brain physiology and pathology
-
Harting K., Knoll B. SIRT2-mediated protein deacetylation: an emerging key regulator in brain physiology and pathology. Eur. J. Cell Biol. 2010, 89:262-269.
-
(2010)
Eur. J. Cell Biol.
, vol.89
, pp. 262-269
-
-
Harting, K.1
Knoll, B.2
-
14
-
-
77957872046
-
Plakoglobin regulates cell motility through Rho- and fibronectin-dependent Src signaling
-
Todorovic V., Desai B.V., Patterson M.J., Amargo E.V., Dubash A.D., Yin T., Jones J.C., Green K.J. Plakoglobin regulates cell motility through Rho- and fibronectin-dependent Src signaling. J. Cell Sci. 2010, 123:3576-3586.
-
(2010)
J. Cell Sci.
, vol.123
, pp. 3576-3586
-
-
Todorovic, V.1
Desai, B.V.2
Patterson, M.J.3
Amargo, E.V.4
Dubash, A.D.5
Yin, T.6
Jones, J.C.7
Green, K.J.8
-
15
-
-
39749143163
-
Sirt2 interacts with 14-3-3 beta/gamma and down-regulates the activity of p53
-
Jin Y.H., Kim Y.J., Kim D.W., Baek K.H., Kang B.Y., Yeo C.Y., Lee K.Y. Sirt2 interacts with 14-3-3 beta/gamma and down-regulates the activity of p53. Biochem. Biophys. Res. Commun. 2008, 368:690-695.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.368
, pp. 690-695
-
-
Jin, Y.H.1
Kim, Y.J.2
Kim, D.W.3
Baek, K.H.4
Kang, B.Y.5
Yeo, C.Y.6
Lee, K.Y.7
-
16
-
-
51449123628
-
Acetylation of Sirt2 by p300 attenuates its deacetylase activity
-
Han Y., Jin Y.H., Kim Y.J., Kang B.Y., Choi H.J., Kim D.W., Yeo C.Y., Lee K.Y. Acetylation of Sirt2 by p300 attenuates its deacetylase activity. Biochem. Biophys. Res. Commun. 2008, 375:576-580.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.375
, pp. 576-580
-
-
Han, Y.1
Jin, Y.H.2
Kim, Y.J.3
Kang, B.Y.4
Choi, H.J.5
Kim, D.W.6
Yeo, C.Y.7
Lee, K.Y.8
-
17
-
-
78650638268
-
SIRT2 down-regulation in HeLa can induce p53 accumulation via p38 MAPK activation-dependent p300 decrease, eventually leading to apoptosis
-
Li Y., Matsumori H., Nakayama Y., Osaki M., Kojima H., Kurimasa A., Ito H., Mori S., Katoh M., Oshimura M., Inoue T. SIRT2 down-regulation in HeLa can induce p53 accumulation via p38 MAPK activation-dependent p300 decrease, eventually leading to apoptosis. Genes Cells 2011, 16:34-45.
-
(2011)
Genes Cells
, vol.16
, pp. 34-45
-
-
Li, Y.1
Matsumori, H.2
Nakayama, Y.3
Osaki, M.4
Kojima, H.5
Kurimasa, A.6
Ito, H.7
Mori, S.8
Katoh, M.9
Oshimura, M.10
Inoue, T.11
-
18
-
-
77950835404
-
SIRT inhibitors induce cell death and p53 acetylation through targeting both SIRT1 and SIRT2
-
Peck B., Chen C.Y., Ho K.K., Di Fruscia P., Myatt S.S., Coombes R.C., Fuchter M.J., Hsiao C.D., Lam E.W. SIRT inhibitors induce cell death and p53 acetylation through targeting both SIRT1 and SIRT2. Mol. Cancer Ther. 2010, 9:844-855.
-
(2010)
Mol. Cancer Ther.
, vol.9
, pp. 844-855
-
-
Peck, B.1
Chen, C.Y.2
Ho, K.K.3
Di Fruscia, P.4
Myatt, S.S.5
Coombes, R.C.6
Fuchter, M.J.7
Hsiao, C.D.8
Lam, E.W.9
-
19
-
-
80255135621
-
P53 deacetylation by SIRT1 decreases during protein kinase CKII downregulation-mediated cellular senescence
-
Jang S.Y., Kim S.Y., Bae Y.S. P53 deacetylation by SIRT1 decreases during protein kinase CKII downregulation-mediated cellular senescence. FEBS Lett. 2011, 585:3360-3366.
-
(2011)
FEBS Lett.
, vol.585
, pp. 3360-3366
-
-
Jang, S.Y.1
Kim, S.Y.2
Bae, Y.S.3
-
20
-
-
84855921054
-
P53 rescue through HDM2 antagonism suppresses melanoma growth and potentiates MEK inhibition
-
Ji Z., Njauw C.N., Taylor M., Neel V., Flaherty K.T., Tsao H. P53 rescue through HDM2 antagonism suppresses melanoma growth and potentiates MEK inhibition. J. Invest. Dermatol. 2012, 132:356-364.
-
(2012)
J. Invest. Dermatol.
, vol.132
, pp. 356-364
-
-
Ji, Z.1
Njauw, C.N.2
Taylor, M.3
Neel, V.4
Flaherty, K.T.5
Tsao, H.6
-
21
-
-
34248177222
-
Mitogen-activated protein kinase kinase inhibition enhances nuclear proapoptotic function of p53 in acute myelogenous leukemia cells
-
Kojima K., Konopleva M., Samudio I.J., Ruvolo V., Andreeff M. Mitogen-activated protein kinase kinase inhibition enhances nuclear proapoptotic function of p53 in acute myelogenous leukemia cells. Cancer Res. 2007, 67:3210-3219.
-
(2007)
Cancer Res.
, vol.67
, pp. 3210-3219
-
-
Kojima, K.1
Konopleva, M.2
Samudio, I.J.3
Ruvolo, V.4
Andreeff, M.5
-
22
-
-
79959873784
-
Reversible acetylation of metabolic enzymes celebration: SIRT2 and p300 join the party
-
Shin J., Zhang D., Chen D. Reversible acetylation of metabolic enzymes celebration: SIRT2 and p300 join the party. Mol. Cell 2011, 43:3-5.
-
(2011)
Mol. Cell
, vol.43
, pp. 3-5
-
-
Shin, J.1
Zhang, D.2
Chen, D.3
-
24
-
-
34447625911
-
Epigenetics and aging: the targets and the marks
-
Fraga M.F., Esteller M. Epigenetics and aging: the targets and the marks. Trends Genet. 2007, 23:413-418.
-
(2007)
Trends Genet.
, vol.23
, pp. 413-418
-
-
Fraga, M.F.1
Esteller, M.2
-
25
-
-
34247547120
-
Human SIRT1: a potential biomarker for tumorigenesis?
-
Lim C.S. Human SIRT1: a potential biomarker for tumorigenesis?. Cell Biol. Int. 2007, 31:636-637.
-
(2007)
Cell Biol. Int.
, vol.31
, pp. 636-637
-
-
Lim, C.S.1
-
26
-
-
15944365507
-
Role of NAD-dependent deacetylases SIRT1 and SIRT2 in radiation and cisplatin-induced cell death in vertebrate cells
-
Matsushita N., Takami Y., Kimura M., Tachiiri S., Ishiai M., Nakayama T., Takata M. Role of NAD-dependent deacetylases SIRT1 and SIRT2 in radiation and cisplatin-induced cell death in vertebrate cells. Genes Cells 2005, 10:321-332.
-
(2005)
Genes Cells
, vol.10
, pp. 321-332
-
-
Matsushita, N.1
Takami, Y.2
Kimura, M.3
Tachiiri, S.4
Ishiai, M.5
Nakayama, T.6
Takata, M.7
|