메뉴 건너뛰기




Volumn 68, Issue 8, 2013, Pages 1889-1893

Do statins protect against the development of Clostridium difficile - associated diarrhoea?

Author keywords

CDI; Predictors; Risk factors; Simvastatin

Indexed keywords

ANTIBIOTIC AGENT; BACTERIAL TOXIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; OMEPRAZOLE; PROTON PUMP INHIBITOR; SIMVASTATIN;

EID: 84880741341     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkt101     Document Type: Article
Times cited : (19)

References (41)
  • 2
    • 0036192008 scopus 로고    scopus 로고
    • Fulminant Clostridium difficile: an underappreciated and increasing cause of death and complications.
    • Dallal RM, Harbrecht BG, Boujoukas AJ et al. Fulminant Clostridium difficile: an underappreciated and increasing cause of death and complications. Ann Surg 2002; 235: 363-72.
    • (2002) Ann Surg , vol.235 , pp. 363-372
    • Dallal, R.M.1    Harbrecht, B.G.2    Boujoukas, A.J.3
  • 3
    • 0031752883 scopus 로고    scopus 로고
    • Risk for Clostridium difficile infection.
    • Bignardi GE. Risk for Clostridium difficile infection. J Hosp Infect 1998; 40: 1-15.
    • (1998) J Hosp Infect , vol.40 , pp. 1-15
    • Bignardi, G.E.1
  • 4
    • 0031926083 scopus 로고    scopus 로고
    • Clostridium difficile infection.
    • Johnson S, Gerding DN. Clostridium difficile infection. Clin Infect Dis 1998; 26: 1027-34.
    • (1998) Clin Infect Dis , vol.26 , pp. 1027-1034
    • Johnson, S.1    Gerding, D.N.2
  • 5
    • 0035436311 scopus 로고    scopus 로고
    • Epidemiology of Clostridium difficile-associated diarrhea.
    • Barbut F, Petit JC. Epidemiology of Clostridium difficile-associated diarrhea. Clin Microbiol Infect 2001; 7: 405-41.
    • (2001) Clin Microbiol Infect , vol.7 , pp. 405-441
    • Barbut, F.1    Petit, J.C.2
  • 7
    • 14844362693 scopus 로고    scopus 로고
    • Length of stay and proton pump inhibitors: key factors in Clostridium difficile-associated diarrhea in nursing home patients.
    • Al-Tureihi FI, Hassoun A, Wolf-Klein G et al. Length of stay and proton pump inhibitors: key factors in Clostridium difficile-associated diarrhea in nursing home patients. J Am Med Dir Assoc 2005; 6: 105-8.
    • (2005) J Am Med Dir Assoc , vol.6 , pp. 105-108
    • Al-Tureihi, F.I.1    Hassoun, A.2    Wolf-Klein, G.3
  • 8
    • 0031982032 scopus 로고    scopus 로고
    • Clinical impact and associated costs of Clostridium difficile-associated diarrhea.
    • Spencer RC. Clinical impact and associated costs of Clostridium difficile-associated diarrhea. J Antimicrob Chemother 1998; 41 Suppl C: 5-12.
    • (1998) J Antimicrob Chemother , vol.41 , Issue.SUPPL. C , pp. 5-12
    • Spencer, R.C.1
  • 9
    • 0036467063 scopus 로고    scopus 로고
    • Health care costs and mortality associated with nosocomial diarrhea.
    • Kyne I, Hamel MB, Polavaram R et al. Health care costs and mortality associated with nosocomial diarrhea. Clin Infect Dis 2002; 34: 346-53.
    • (2002) Clin Infect Dis , vol.34 , pp. 346-353
    • Kyne, I.1    Hamel, M.B.2    Polavaram, R.3
  • 10
    • 0034072716 scopus 로고    scopus 로고
    • Clostridium difficile-associated diarrhea in hospitalized patients.
    • Al-Eidan FA, McElnay JC, Scott MG et al. Clostridium difficile-associated diarrhea in hospitalized patients. J Clin Pharm Ther 2000; 25: 101-9.
    • (2000) J Clin Pharm Ther , vol.25 , pp. 101-109
    • Al-Eidan, F.A.1    McElnay, J.C.2    Scott, M.G.3
  • 11
    • 0038648403 scopus 로고    scopus 로고
    • Antibiotics and hospital-acquired Clostridium difficile-associated diarrhoea: a systemic review.
    • Thomas C, Stevenson M, Riley TV. Antibiotics and hospital-acquired Clostridium difficile-associated diarrhoea: a systemic review. J Antimicrob Chemother 2003; 51: 1339-50.
    • (2003) J Antimicrob Chemother , vol.51 , pp. 1339-1350
    • Thomas, C.1    Stevenson, M.2    Riley, T.V.3
  • 12
    • 34247550291 scopus 로고    scopus 로고
    • Predicting Clostridium difficile toxin in hospitalized patients with antibiotic-associated diarrhea.
    • Peled N, Pitlik S, Samra Z et al. Predicting Clostridium difficile toxin in hospitalized patients with antibiotic-associated diarrhea. Infect Control Hosp Epidemiol 2007; 28: 377-81.
    • (2007) Infect Control Hosp Epidemiol , vol.28 , pp. 377-381
    • Peled, N.1    Pitlik, S.2    Samra, Z.3
  • 13
    • 29144473282 scopus 로고    scopus 로고
    • Use of gastric acid-suppressive agents and the risk of community-acquired Clostridium difficile-associated diarrhea.
    • Dial S, Delaney JA, Barkun AN et al. Use of gastric acid-suppressive agents and the risk of community-acquired Clostridium difficile-associated diarrhea. JAMA 2005; 21: 2989-95.
    • (2005) JAMA , vol.21 , pp. 2989-2995
    • Dial, S.1    Delaney, J.A.2    Barkun, A.N.3
  • 14
    • 33746413402 scopus 로고    scopus 로고
    • Proton pump inhibitor therapy is a risk factor for Clostridium difficile-associated diarrhea.
    • Yearsley KA, Gilby LJ, Ramadas AV et al. Proton pump inhibitor therapy is a risk factor for Clostridium difficile-associated diarrhea. Aliment Pharmacol Ther 2006; 24: 613-9.
    • (2006) Aliment Pharmacol Ther , vol.24 , pp. 613-619
    • Yearsley, K.A.1    Gilby, L.J.2    Ramadas, A.V.3
  • 15
    • 31844451010 scopus 로고    scopus 로고
    • Anti-inflammatory of statins: clinical evidence and basic mechanisms.
    • Jain MK, Ridker PM. Anti-inflammatory of statins: clinical evidence and basic mechanisms. Nat Rev Drug Discov 2005; 4: 977-87.
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 977-987
    • Jain, M.K.1    Ridker, P.M.2
  • 16
    • 78349267131 scopus 로고    scopus 로고
    • Long-term statin therapy affects the severity of chronic gastritis.
    • Nseir W, Khateeb J, Tatour I et al. Long-term statin therapy affects the severity of chronic gastritis. Helicobacter 2010; 15: 510-5.
    • (2010) Helicobacter , vol.15 , pp. 510-515
    • Nseir, W.1    Khateeb, J.2    Tatour, I.3
  • 17
    • 84857783306 scopus 로고    scopus 로고
    • The impact of long-term versus short-term statin use on the mortality of bacteraemic patients.
    • Nseir W, Mograbi J, Abu-Elheja O et al. The impact of long-term versus short-term statin use on the mortality of bacteraemic patients. Infection 2012; 40: 41-8.
    • (2012) Infection , vol.40 , pp. 41-48
    • Nseir, W.1    Mograbi, J.2    Abu-Elheja, O.3
  • 18
    • 84867030101 scopus 로고    scopus 로고
    • Statin use and the risk of Clostridium difficile in academic medical centers.
    • Motzkus-Feaganus CA, Pakyz A, Polk R et al. Statin use and the risk of Clostridium difficile in academic medical centers. Gut 2012; 61: 1538-42.
    • (2012) Gut , vol.61 , pp. 1538-1542
    • Motzkus-Feaganus, C.A.1    Pakyz, A.2    Polk, R.3
  • 19
    • 34547769908 scopus 로고    scopus 로고
    • Simvastatin inhibits IFN-g-induced CD40 gene expression by suppressing STAT-1a.
    • Lee SJ, Qin H, Benveniste EN. Simvastatin inhibits IFN-g-induced CD40 gene expression by suppressing STAT-1a. J Leukoc Biol 2007; 82: 436-47.
    • (2007) J Leukoc Biol , vol.82 , pp. 436-447
    • Lee, S.J.1    Qin, H.2    Benveniste, E.N.3
  • 20
    • 79952458113 scopus 로고    scopus 로고
    • A case-control study of community-associated Clostridium difficile infection: no role for proton pump inhibitors.
    • Naggie S, Miller BA, Zuzak KB et al. A case-control study of community-associated Clostridium difficile infection: no role for proton pump inhibitors. Am J Med 2011; 124: 276-7.
    • (2011) Am J Med , vol.124 , pp. 276-277
    • Naggie, S.1    Miller, B.A.2    Zuzak, K.B.3
  • 21
    • 84868546746 scopus 로고    scopus 로고
    • Can we identify patients at high risk of recurrent Clostridium difficile infection?
    • Kelly CP. Can we identify patients at high risk of recurrent Clostridium difficile infection? Clin Microbiol Infect 2012; 18 Suppl 6: 21-7.
    • (2012) Clin Microbiol Infect , vol.6 , pp. 21-27
    • Kelly, C.P.1
  • 22
    • 0026177727 scopus 로고
    • Risk factors for the development of Clostridium difficile-associated diarrhea during a hospital outbreak.
    • Thibault A, Miller MA, Gaese C. Risk factors for the development of Clostridium difficile-associated diarrhea during a hospital outbreak. Infect Control Hosp Epidemiol 1991; 12: 345-8.
    • (1991) Infect Control Hosp Epidemiol , vol.12 , pp. 345-348
    • Thibault, A.1    Miller, M.A.2    Gaese, C.3
  • 23
    • 2642559507 scopus 로고    scopus 로고
    • Beyond the laboratory: clinical implications for statin pleiotropy.
    • Halcox JP, Deanfield JE. Beyond the laboratory: clinical implications for statin pleiotropy. Circulation 2004; 109 Suppl II: II-42-8.
    • (2004) Circulation , vol.109 , Issue.SUPPL. II
    • Halcox, J.P.1    Deanfield, J.E.2
  • 24
    • 4344627319 scopus 로고    scopus 로고
    • Lipid-altering changes and pleiotropic effects of atorvastatin in patients with hypercholesterolemia.
    • Sakabe K, Fukuda N, Wakayama K et al. Lipid-altering changes and pleiotropic effects of atorvastatin in patients with hypercholesterolemia. Am J Cardiol 2004; 94: 497-500.
    • (2004) Am J Cardiol , vol.94 , pp. 497-500
    • Sakabe, K.1    Fukuda, N.2    Wakayama, K.3
  • 26
    • 0035162266 scopus 로고    scopus 로고
    • Simvastatin has anti-inflammatory and antiatherosclerotic activities independent of plasma cholesterol lowering.
    • Sparrow CP, Burton CA, Hernandez M et al. Simvastatin has anti-inflammatory and antiatherosclerotic activities independent of plasma cholesterol lowering. Arterioscler Thromb Vasc Biol 2001; 21: 115-21.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 115-121
    • Sparrow, C.P.1    Burton, C.A.2    Hernandez, M.3
  • 27
    • 0141615830 scopus 로고    scopus 로고
    • 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors decrease Fas ligand expression and cytotoxicity in activated human T lymphocytes.
    • Blanco-Colio LM, Munoz-Gracia B, Martin-Vetura JL et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors decrease Fas ligand expression and cytotoxicity in activated human T lymphocytes. Circulation 2003; 108: 1506-13.
    • (2003) Circulation , vol.108 , pp. 1506-1513
    • Blanco-Colio, L.M.1    Munoz-Gracia, B.2    Martin-Vetura, J.L.3
  • 28
    • 0344013648 scopus 로고    scopus 로고
    • Inhibition of hydroxymethylglutaryl coenzyme A reductase reduces Th1 development and promotes Th2 development.
    • Hakamada-Taguchi R, Uehara Y, Kuribayashi K et al. Inhibition of hydroxymethylglutaryl coenzyme A reductase reduces Th1 development and promotes Th2 development. Circ Res 2003; 93: 948-56.
    • (2003) Circ Res , vol.93 , pp. 948-956
    • Hakamada-Taguchi, R.1    Uehara, Y.2    Kuribayashi, K.3
  • 29
    • 0036192275 scopus 로고    scopus 로고
    • 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, atorvastatin and simvastatin, induce apoptosis of vascular smooth muscle cells by downregulation of Bcl-2 expression and Rho A prenylation.
    • Blanco-Colio LM, Villa A, Ortego M et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, atorvastatin and simvastatin, induce apoptosis of vascular smooth muscle cells by downregulation of Bcl-2 expression and Rho A prenylation. Atherosclerosis 2002; 161: 17-26.
    • (2002) Atherosclerosis , vol.161 , pp. 17-26
    • Blanco-Colio, L.M.1    Villa, A.2    Ortego, M.3
  • 30
    • 33947260554 scopus 로고    scopus 로고
    • Rho-glucosylating Clostridium difficile toxins A and B: new insights into structure and function.
    • Jank T, Giesmann T, Aktories K. Rho-glucosylating Clostridium difficile toxins A and B: new insights into structure and function. Glycobiology 2007; 17: 15R-22R.
    • (2007) Glycobiology , vol.17
    • Jank, T.1    Giesmann, T.2    Aktories, K.3
  • 31
    • 70449727756 scopus 로고    scopus 로고
    • Clinically important interaction between statin drugs and Clostridium difficile toxin?
    • McGuire T, Dobesh P, Klepser D et al. Clinically important interaction between statin drugs and Clostridium difficile toxin? Med Hypotheses 2009; 73: 1045-7.
    • (2009) Med Hypotheses , vol.73 , pp. 1045-1047
    • McGuire, T.1    Dobesh, P.2    Klepser, D.3
  • 32
    • 0037109098 scopus 로고    scopus 로고
    • Simvastatin inhibits inflammatory properties of Staphylococcus aureus a-toxin.
    • Pruefer D, Makowski J, Schmell M et al. Simvastatin inhibits inflammatory properties of Staphylococcus aureus a-toxin. Circulation 2002; 106: 2104-10.
    • (2002) Circulation , vol.106 , pp. 2104-2110
    • Pruefer, D.1    Makowski, J.2    Schmell, M.3
  • 33
    • 0035887840 scopus 로고    scopus 로고
    • The effect of statins on mortality in patients with bacteremia.
    • Liappis AP, Kan VL, Rochester CG et al. The effect of statins on mortality in patients with bacteremia. Clin Infect Dis 2001; 33: 1352-7.
    • (2001) Clin Infect Dis , vol.33 , pp. 1352-1357
    • Liappis, A.P.1    Kan, V.L.2    Rochester, C.G.3
  • 34
    • 84860583669 scopus 로고    scopus 로고
    • Antibacterial activity of statins: a comparative study of atorvastatin, simvastatin, and rosuvastatin.
    • Masadeh M, Mhaidat N, Alzoubi K et al. Antibacterial activity of statins: a comparative study of atorvastatin, simvastatin, and rosuvastatin. Am Clin Microbiol Antimicrob 2012; 11: 13.
    • (2012) Am Clin Microbiol Antimicrob , vol.11 , pp. 13
    • Masadeh, M.1    Mhaidat, N.2    Alzoubi, K.3
  • 35
    • 29844445926 scopus 로고    scopus 로고
    • Statin therapy is associated with fewer deaths in patients with bacteraemia.
    • Kruger P, Fitzsimmons K, Cook D et al. Statin therapy is associated with fewer deaths in patients with bacteraemia. Intensive Care Med 2006; 32: 75-9.
    • (2006) Intensive Care Med , vol.32 , pp. 75-79
    • Kruger, P.1    Fitzsimmons, K.2    Cook, D.3
  • 36
    • 70350066800 scopus 로고    scopus 로고
    • Statins for the prevention and treatment of infections: a systematic review and meta-analysis.
    • Tleyjeh IM, Kashour T, Hakim FA et al. Statins for the prevention and treatment of infections: a systematic review and meta-analysis. Arch Intern Med 2009; 169: 1658-67.
    • (2009) Arch Intern Med , vol.169 , pp. 1658-1667
    • Tleyjeh, I.M.1    Kashour, T.2    Hakim, F.A.3
  • 37
    • 84863334609 scopus 로고    scopus 로고
    • Randomized clinical trial: simvastatin as adjuvant therapy improves significantly the Helicobacter pylori eradication rate - a placebo-controlled study.
    • Nseir W, Diab H, Mahamid M et al. Randomized clinical trial: simvastatin as adjuvant therapy improves significantly the Helicobacter pylori eradication rate - a placebo-controlled study. Aliment Pharmacol Ther 2012; 36: 231-8.
    • (2012) Aliment Pharmacol Ther , vol.36 , pp. 231-238
    • Nseir, W.1    Diab, H.2    Mahamid, M.3
  • 38
    • 0034681953 scopus 로고    scopus 로고
    • Hydroxymethylglutaryl coenzyme A reductase inhibitors modify the inflammatory response of human macrophages and endothelial cells infected with Chlamydia pneumoniae.
    • Kothe H, Dalhoff H, Rupp J et al. Hydroxymethylglutaryl coenzyme A reductase inhibitors modify the inflammatory response of human macrophages and endothelial cells infected with Chlamydia pneumoniae. Circulation 2000; 101: 1760-3.
    • (2000) Circulation , vol.101 , pp. 1760-1763
    • Kothe, H.1    Dalhoff, H.2    Rupp, J.3
  • 39
    • 3042511702 scopus 로고    scopus 로고
    • Bacteriotherapy using fecal flora: toying with human motions.
    • Borody TJ, Warren EF, Leis SM et al. Bacteriotherapy using fecal flora: toying with human motions. Clin Gastroenterol 2004; 38: 475-83.
    • (2004) Clin Gastroenterol , vol.38 , pp. 475-483
    • Borody, T.J.1    Warren, E.F.2    Leis, S.M.3
  • 40
    • 0036241355 scopus 로고    scopus 로고
    • Changes in predominant bacterial population in human feces with age and with Clostridium difficile infection.
    • Hopkins MJ, Macfarlane GT. Changes in predominant bacterial population in human feces with age and with Clostridium difficile infection. J Med Microbiol 2002; 51: 448-54.
    • (2002) J Med Microbiol , vol.51 , pp. 448-454
    • Hopkins, M.J.1    Macfarlane, G.T.2
  • 41
    • 78650370258 scopus 로고    scopus 로고
    • Comparative metagenomic study of alterations to the intestinal microbiota and risk of nosocomial Clostridium difficile-associated disease.
    • Manges AR, Labbe A, Loo VG et al. Comparative metagenomic study of alterations to the intestinal microbiota and risk of nosocomial Clostridium difficile-associated disease. J Infect Dis 2010; 202: 1877-84.
    • (2010) J Infect Dis , vol.202 , pp. 1877-1884
    • Manges, A.R.1    Labbe, A.2    Loo, V.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.