메뉴 건너뛰기




Volumn 12, Issue 2, 2013, Pages 214-223

Incretins and bone: Evolving concepts in nutrientdependent regulation of bone turnover

Author keywords

Bone remodeling; GIP; GLP 1; GLP 2; Incretins

Indexed keywords

EXENDIN 4; GASTRIC INHIBITORY POLYPEPTIDE; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 2; INCRETIN; INSULIN GLARGINE; LIRAGLUTIDE; TEDUGLUTIDE;

EID: 84880730516     PISSN: 11093099     EISSN: None     Source Type: Journal    
DOI: 10.14310/horm.2002.1405     Document Type: Review
Times cited : (22)

References (63)
  • 1
    • 0031786307 scopus 로고    scopus 로고
    • Serum CrossLaps One Step ELISA. First application of monoclonal antibodies for measurement in serum of bone-related degradation products from C-terminal telopeptides of type I collagen
    • Rosenquist C, Fledelius C, Christgau S, et al, 1998 Serum CrossLaps One Step ELISA. First application of monoclonal antibodies for measurement in serum of bone-related degradation products from C-terminal telopeptides of type I collagen. Clin Chem 44: 2281-2289.
    • (1998) Clin Chem , vol.44 , pp. 2281-2289
    • Rosenquist, C.1    Fledelius, C.2    Christgau, S.3
  • 2
    • 0028859422 scopus 로고
    • Measurement of a more stable region of osteocalcin in serum by ELISA with two monoclonal antibodies
    • Rosenquist C, Qvist P, Bjarnason N, Christiansen C, 1995 Measurement of a more stable region of osteocalcin in serum by ELISA with two monoclonal antibodies. Clin Chem 41: 1439-1445.
    • (1995) Clin Chem , vol.41 , pp. 1439-1445
    • Rosenquist, C.1    Qvist, P.2    Bjarnason, N.3    Christiansen, C.4
  • 3
    • 0031962776 scopus 로고    scopus 로고
    • Circadian variation of urinary type I collagen crosslinked C-telopeptide and free and peptide-bound forms of pyridinium crosslinks
    • Aoshima H, Kushida K, Takahashi M, et al, 1998 Circadian variation of urinary type I collagen crosslinked C-telopeptide and free and peptide-bound forms of pyridinium crosslinks. Bone 22: 73-78.
    • (1998) Bone , vol.22 , pp. 73-78
    • Aoshima, H.1    Kushida, K.2    Takahashi, M.3
  • 6
    • 0031875640 scopus 로고    scopus 로고
    • Application of a new serum assay for type I collagen cross-linked N-telopeptides: Assessment of diurnal changes in bone turnover with and without alendronate treatment
    • Gertz BJ, Clemens JD, Holland SD, Yuan W, Greenspan S, 1998 Application of a new serum assay for type I collagen cross-linked N-telopeptides: assessment of diurnal changes in bone turnover with and without alendronate treatment. Calcif Tissue Int 63: 102-106.
    • (1998) Calcif Tissue Int , vol.63 , pp. 102-106
    • Gertz, B.J.1    Clemens, J.D.2    Holland, S.D.3    Yuan, W.4    Greenspan, S.5
  • 7
    • 0026621627 scopus 로고
    • Diurnal variation in serum markers of type I collagen synthesis and degradation in healthy premenopausal women
    • Hassanger C, Risteli J, Risteli L, Jensen SB, Christiansen C, 1992 Diurnal variation in serum markers of type I collagen synthesis and degradation in healthy premenopausal women. J Bone Miner Res 7: 1307-1311.
    • (1992) J Bone Miner Res , vol.7 , pp. 1307-1311
    • Hassanger, C.1    Risteli, J.2    Risteli, L.3    Jensen, S.B.4    Christiansen, C.5
  • 8
    • 0031791829 scopus 로고    scopus 로고
    • Effects of the circadian variation in serum cortisol on markers of bone turnover and calcium homeostasis in normal postmenopausal women
    • Heshmati HM, Riggs BL, Burritt MF, McAlister CA, Wollan PC, Khosla S, 1998 Effects of the circadian variation in serum cortisol on markers of bone turnover and calcium homeostasis in normal postmenopausal women. J Clin Endocrinol Metab 83: 751-756.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 751-756
    • Heshmati, H.M.1    Riggs, B.L.2    Burritt, M.F.3    McAlister, C.A.4    Wollan, P.C.5    Khosla, S.6
  • 10
    • 0031907294 scopus 로고    scopus 로고
    • The physiology and pharmacology of melatonin in humans
    • Geoffriau M, Brun J, Chazot G, Claustrat B, 1998 The physiology and pharmacology of melatonin in humans. Horm Res 49: 136-141.
    • (1998) Horm Res , vol.49 , pp. 136-141
    • Geoffriau, M.1    Brun, J.2    Chazot, G.3    Claustrat, B.4
  • 11
    • 0035030275 scopus 로고    scopus 로고
    • Assessment of the relationship between circadian variations of salivary melatonin levels and type I collagen metabolism in postmenopausal obese women
    • Ostrowska Z, Kos-Kudla B, Marek B, Swietochowska E, Gorski J, 2001 Assessment of the relationship between circadian variations of salivary melatonin levels and type I collagen metabolism in postmenopausal obese women. Neuro Endocrinol Lett. 22: 121-127.
    • (2001) Neuro Endocrinol Lett , vol.22 , pp. 121-127
    • Ostrowska, Z.1    Kos-Kudla, B.2    Marek, B.3    Swietochowska, E.4    Gorski, J.5
  • 12
    • 0036309083 scopus 로고    scopus 로고
    • Circadian variation in the serum concentration of C-terminal telopeptide of type I collagen (serum CTx): Effects of gender, age, menopausal status, posture, daylight, serum cortisol, and fasting
    • Qvist P, Christgau S, Pedersen BJ, Schlemmer A, Christiansen C, 2002 Circadian variation in the serum concentration of C-terminal telopeptide of type I collagen (serum CTx): effects of gender, age, menopausal status, posture, daylight, serum cortisol, and fasting. Bone 31: 57-61.
    • (2002) Bone , vol.31 , pp. 57-61
    • Qvist, P.1    Christgau, S.2    Pedersen, B.J.3    Schlemmer, A.4    Christiansen, C.5
  • 13
    • 0032935108 scopus 로고    scopus 로고
    • Acute fasting diminishes the circadian rhythm of biochemical markers of bone resorption
    • Schlemmer A, Hassager C, 1999 Acute fasting diminishes the circadian rhythm of biochemical markers of bone resorption. Eur J Endocrinol 140: 332-337.
    • (1999) Eur J Endocrinol , vol.140 , pp. 332-337
    • Schlemmer, A.1    Hassager, C.2
  • 14
    • 34247474111 scopus 로고    scopus 로고
    • The gut feeling of bone remodeling
    • 16-15
    • Henriksen DB, 2005 The gut feeling of bone remodeling IBMS BoneKEy 2: 16-15.
    • (2005) IBMS BoneKEy , vol.2
    • Henriksen, D.B.1
  • 15
    • 0036319732 scopus 로고    scopus 로고
    • Acute changes of bone turnover and PTH induced by insulin and glucose: Euglycemic and hypoglycemic hyperinsulinemic clamp studies
    • Clowes JA, Robinson RT, Heller SR, Eastell R, Blumsohn A, 2002 Acute changes of bone turnover and PTH induced by insulin and glucose: Euglycemic and hypoglycemic hyperinsulinemic clamp studies. J Clin Endocrinol Metab 87: 3324-3329.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3324-3329
    • Clowes, J.A.1    Robinson, R.T.2    Heller, S.R.3    Eastell, R.4    Blumsohn, A.5
  • 17
    • 79957717049 scopus 로고    scopus 로고
    • Response of biochemical markers of bone turnover to oral glucose load in diseases that affect bone metabolism
    • Yavropoulou MP, Tomos K, Tsekmekidou X, et al, 2011 Response of biochemical markers of bone turnover to oral glucose load in diseases that affect bone metabolism. Eur J Endocrinol 164: 1035-1041.
    • (2011) Eur J Endocrinol , vol.164 , pp. 1035-1041
    • Yavropoulou, M.P.1    Tomos, K.2    Tsekmekidou, X.3
  • 18
    • 10744224629 scopus 로고    scopus 로고
    • Role of gastrointestinal hormones in postprandial reduction of bone resorption
    • Henriksen DB, Alexandersen P, Bjarnason NH, et al, 2003 Role of gastrointestinal hormones in postprandial reduction of bone resorption. J Bone Miner Res 18: 2180-2189.
    • (2003) J Bone Miner Res , vol.18 , pp. 2180-2189
    • Henriksen, D.B.1    Alexandersen, P.2    Bjarnason, N.H.3
  • 20
    • 0030918237 scopus 로고    scopus 로고
    • The intestine, an endocrine organ
    • Schmidt WE, 1997 The intestine, an endocrine organ. Digestion 58: 56-58.
    • (1997) Digestion , vol.58 , pp. 56-58
    • Schmidt, W.E.1
  • 21
    • 0037902984 scopus 로고    scopus 로고
    • Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus
    • Vilsboll T, Krarup T, Sonne J, et al, 2003 Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus. J Clin Endocrinol Metab 88: 2706-2713.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2706-2713
    • Vilsboll, T.1    Krarup, T.2    Sonne, J.3
  • 22
    • 0015103223 scopus 로고
    • A gastric inhibitory polypeptide. II. The complete amino acid sequence
    • Brown JC, Dryburgh JR, 1971 A gastric inhibitory polypeptide. II. The complete amino acid sequence. Can J Biochem 49: 867-872.
    • (1971) Can J Biochem , vol.49 , pp. 867-872
    • Brown, J.C.1    Dryburgh, J.R.2
  • 23
    • 1942454241 scopus 로고    scopus 로고
    • Glucosedependent insulinotropic peptide: Differential effects on hepatic artery vs. portal vein endothelial cells
    • Ding KH, Zhong Q, Xu J, Isales CM, 2004 Glucosedependent insulinotropic peptide: differential effects on hepatic artery vs. portal vein endothelial cells. Am J Physiol Endocrinol Metab 286: E773-779.
    • (2004) Am J Physiol Endocrinol Metab , vol.286
    • Ding, K.H.1    Zhong, Q.2    Xu, J.3    Isales, C.M.4
  • 24
    • 0029043139 scopus 로고
    • Cell and molecular biology of the incretin hormones glucagon-like peptide-I and glucose-dependent insulin releasing polypeptide
    • Fehmann HC, Goke R, Goke B, 1995 Cell and molecular biology of the incretin hormones glucagon-like peptide-I and glucose-dependent insulin releasing polypeptide. Endocrine Reviews 16: 390-410.
    • (1995) Endocrine Reviews , vol.16 , pp. 390-410
    • Fehmann, H.C.1    Goke, R.2    Goke, B.3
  • 25
    • 0030093033 scopus 로고    scopus 로고
    • Nutrientinduced secretion and metabolic effects of glucosedependent insulinotropic polypeptide and glucagon-like peptide-1
    • Knapper JM, Morgan LM, Fletcher JM, 1996 Nutrientinduced secretion and metabolic effects of glucosedependent insulinotropic polypeptide and glucagon-like peptide-1. Proc Nutr Soc 55: 291-305.
    • (1996) Proc Nutr Soc , vol.55 , pp. 291-305
    • Knapper, J.M.1    Morgan, L.M.2    Fletcher, J.M.3
  • 26
    • 0024215270 scopus 로고
    • Effects of synthetic human gastric inhibitory polypeptide on splachnic circulation in dogs
    • Kogire M, Inoue K, Sumi S, Doi R, Takaori K, Yun M, 1988 Effects of synthetic human gastric inhibitory polypeptide on splachnic circulation in dogs. Gastroenterology 95: 1636-1640.
    • (1988) Gastroenterology , vol.95 , pp. 1636-1640
    • Kogire, M.1    Inoue, K.2    Sumi, S.3    Doi, R.4    Takaori, K.5    Yun, M.6
  • 28
    • 0027136670 scopus 로고
    • Gastric inhibitory polypeptide receptor, a member of the secretin-vasoactive intestinal peptide receptor family, is widely distributed in peripheral organs and the brain
    • Usdin TB, Mezey E, Button DC, Brownstein MJ, Bonner TI, 1993 Gastric inhibitory polypeptide receptor, a member of the secretin-vasoactive intestinal peptide receptor family, is widely distributed in peripheral organs and the brain. Endocrinology 133: 2861-2870.
    • (1993) Endocrinology , vol.133 , pp. 2861-2870
    • Usdin, T.B.1    Mezey, E.2    Button, D.C.3    Brownstein, M.J.4    Bonner, T.I.5
  • 29
    • 0029118049 scopus 로고
    • Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV
    • Kieffer TJ, McIntosh CH, Pederson RA, 1995 Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV. Endocrinology 136: 3585-3596.
    • (1995) Endocrinology , vol.136 , pp. 3585-3596
    • Kieffer, T.J.1    McIntosh, C.H.2    Pederson, R.A.3
  • 30
    • 34147142997 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic peptide-overexpressing transgenic mice have increased bone mass
    • Xie D, Zhong Q, Ding KH, et al, 2007 Glucose-dependent insulinotropic peptide-overexpressing transgenic mice have increased bone mass. Bone 40: 1352-1360.
    • (2007) Bone , vol.40 , pp. 1352-1360
    • Xie, D.1    Zhong, Q.2    Ding, K.H.3
  • 31
    • 28844478542 scopus 로고    scopus 로고
    • Glucosedependent insulinotropic polypeptide receptor knockout mice have altered bone turnover
    • Xie D, Cheng H, Hamrick M, et al, 2005 Glucosedependent insulinotropic polypeptide receptor knockout mice have altered bone turnover. Bone 37: 759-769.
    • (2005) Bone , vol.37 , pp. 759-769
    • Xie, D.1    Cheng, H.2    Hamrick, M.3
  • 32
    • 17744374566 scopus 로고    scopus 로고
    • Osteoblastderived cells express functional glucose-dependent insulinotropic peptide receptors
    • Bollag RJ, Zhong Q, Phillips P, et al, 2000 Osteoblastderived cells express functional glucose-dependent insulinotropic peptide receptors. Endocrinology 141: 1228-1235.
    • (2000) Endocrinology , vol.141 , pp. 1228-1235
    • Bollag, R.J.1    Zhong, Q.2    Phillips, P.3
  • 34
    • 33745658853 scopus 로고    scopus 로고
    • Gastric inhibitory polypeptide as an endogenous factor promoting new bone formation after food ingestion
    • Tsukiyama K, Yamada Y, Yamada C, et al 2006 Gastric inhibitory polypeptide as an endogenous factor promoting new bone formation after food ingestion. Molecular Endocrinology 20: 1644-1651.
    • (2006) Molecular Endocrinology , vol.20 , pp. 1644-1651
    • Tsukiyama, K.1    Yamada, Y.2    Yamada, C.3
  • 35
    • 41849094819 scopus 로고    scopus 로고
    • Impact of glucose-dependent insulinotropic peptide on age-induced bone loss
    • Ding KH, Shi XM, Zhong Q, et al, 2008 Impact of glucose-dependent insulinotropic peptide on age-induced bone loss. J Bone Miner Res 23: 536-543.
    • (2008) J Bone Miner Res , vol.23 , pp. 536-543
    • Ding, K.H.1    Shi, X.M.2    Zhong, Q.3
  • 36
    • 33846866509 scopus 로고    scopus 로고
    • Effects of glucose-dependent insulinotropic peptide on osteoclast function
    • Zhong Q, Itokawa T, Sridhar S, et al, 2007 Effects of glucose-dependent insulinotropic peptide on osteoclast function. Am J Physiol Endocrinol Metab 292: E543-548.
    • (2007) Am J Physiol Endocrinol Metab , vol.292
    • Zhong, Q.1    Itokawa, T.2    Sridhar, S.3
  • 38
    • 29644431787 scopus 로고    scopus 로고
    • Immunocompetent properties of human osteoblasts: Interactions with T lymphocytes
    • Stanley KT, Van Dort C, Motyl C, Endres J, Fox DA, 2006 Immunocompetent properties of human osteoblasts: interactions with T lymphocytes. J Bone Miner Res 21: 29-36.
    • (2006) J Bone Miner Res , vol.21 , pp. 29-36
    • Stanley, K.T.1    van Dort, C.2    Motyl, C.3    Endres, J.4    Fox, D.A.5
  • 39
    • 54949149093 scopus 로고    scopus 로고
    • Pro(3)GIP[mPEG]: Novel, long-acting, mPEGylated antagonist of gastric inhibitory polypeptide for obesity-diabetes (diabesity) therapy
    • McClean PL, Irwin N, Hunter K, Gault VA, Flatt PR, 2008 (Pro(3))GIP[mPEG]: novel, long-acting, mPEGylated antagonist of gastric inhibitory polypeptide for obesity-diabetes (diabesity) therapy. Br J Pharmacol 155: 690-701.
    • (2008) Br J Pharmacol , vol.155 , pp. 690-701
    • McClean, P.L.1    Irwin, N.2    Hunter, K.3    Gault, V.A.4    Flatt, P.R.5
  • 40
    • 33846637891 scopus 로고    scopus 로고
    • Metabolic effects of sub-chronic ablation of the incretin receptors by daily administration of (Pro3)GIP and exendin(9-39) amide in obese diabetic (ob/ob) mice
    • Parker JC, Irwin N, Lavery KS, et al, 2007 Metabolic effects of sub-chronic ablation of the incretin receptors by daily administration of (Pro3)GIP and exendin(9-39) amide in obese diabetic (ob/ob) mice. Biol Chem 388: 221-226.
    • (2007) Biol Chem , vol.388 , pp. 221-226
    • Parker, J.C.1    Irwin, N.2    Lavery, K.S.3
  • 41
    • 0036317496 scopus 로고    scopus 로고
    • Dipeptidyl peptidase IV-resistant [D-Ala(2)] glucosedependent insulinotropic polypeptide (GIP) improves glucose tolerance in normal and obese diabetic rats
    • Hinke SA, Gelling RW, Pederson RA, et al, 2002 Dipeptidyl peptidase IV-resistant [D-Ala(2)] glucosedependent insulinotropic polypeptide (GIP) improves glucose tolerance in normal and obese diabetic rats. Diabetes 51: 652-661.
    • (2002) Diabetes , vol.51 , pp. 652-661
    • Hinke, S.A.1    Gelling, R.W.2    Pederson, R.A.3
  • 42
    • 15044352155 scopus 로고    scopus 로고
    • The [pre-] history of the incretin concept
    • Creutzfeldt W, 2005 The [pre-] history of the incretin concept. Regulatory Peptides 128: 87-91.
    • (2005) Regulatory Peptides , vol.128 , pp. 87-91
    • Creutzfeldt, W.1
  • 43
    • 34248223285 scopus 로고    scopus 로고
    • Biology of incretins: GLP-1and GLP-2
    • Baggio LL, Drucker DJ, 2007 Biology of incretins: GLP-1and GLP-2. Gastrenterology 132: 2131-2157.
    • (2007) Gastrenterology , vol.132 , pp. 2131-2157
    • Baggio, L.L.1    Drucker, D.J.2
  • 45
    • 38549146030 scopus 로고    scopus 로고
    • The murine glucagonlike peptide-1 receptor is essential for control of bone resorption
    • Yamada C, Yamada Y, Tsukiyama K, et al, 2008 The murine glucagonlike peptide-1 receptor is essential for control of bone resorption. Endocrinology 149: 574-579.
    • (2008) Endocrinology , vol.149 , pp. 574-579
    • Yamada, C.1    Yamada, Y.2    Tsukiyama, K.3
  • 46
    • 0030590526 scopus 로고    scopus 로고
    • Expression of glucagon-like peptide 1 receptor in a murine C cell line: Regulation of calcitonin gene by glucagon-like peptide 1
    • Lamari Y, Boissard C, Moukhtar MS, Jullienne A, Rosselin G, Garel JM, 1996 Expression of glucagon-like peptide 1 receptor in a murine C cell line: regulation of calcitonin gene by glucagon-like peptide 1. FEBS Lett 393: 248-252.
    • (1996) FEBS Lett , vol.393 , pp. 248-252
    • Lamari, Y.1    Boissard, C.2    Moukhtar, M.S.3    Jullienne, A.4    Rosselin, G.5    Garel, J.M.6
  • 47
    • 0029833629 scopus 로고    scopus 로고
    • Effects of glucagon and glucagon-like peptide-1-(7-36) amide on C cells from rat thyroid and medullary thyroid carcinoma CA-77 cell line
    • Crespel A, De Boisvilliers F, Gros L, Kervran A, 1996 Effects of glucagon and glucagon-like peptide-1-(7-36) amide on C cells from rat thyroid and medullary thyroid carcinoma CA-77 cell line. Endocrinology 137: 3674-3680.
    • (1996) Endocrinology , vol.137 , pp. 3674-3680
    • Crespel, A.1    de Boisvilliers, F.2    Gros, L.3    Kervran, A.4
  • 48
    • 67349094596 scopus 로고    scopus 로고
    • Effect of GLP-1 treatment on bone turnover in normal, type 2 diabetic, and insulin-resistant states
    • Nuche-Berenguer B, Moreno P, Esbrit P, et al, 2009 Effect of GLP-1 treatment on bone turnover in normal, type 2 diabetic, and insulin-resistant states. Calcif Tissue Int 84: 453-461.
    • (2009) Calcif Tissue Int , vol.84 , pp. 453-461
    • Nuche-Berenguer, B.1    Moreno, P.2    Esbrit, P.3
  • 49
    • 71449084965 scopus 로고    scopus 로고
    • Exendin-4 exerts osteogenic actions in insulinresistant and type 2 diabetic states
    • Nuche-Berenguer B, Moreno P, Portal-Nuñez S, et al, 2010 Exendin-4 exerts osteogenic actions in insulinresistant and type 2 diabetic states. Regul Pept 159: 61-66.
    • (2010) Regul Pept , vol.159 , pp. 61-66
    • Nuche-Berenguer, B.1    Moreno, P.2    Portal-Nuñez, S.3
  • 50
    • 79954782586 scopus 로고    scopus 로고
    • GLP-1 and exendin-4 can reverse hyperlipidicrelated osteopenia
    • Nuche-Berenguer B, Lozano D, Gutiérrez-Rojas I, et al, 2011 GLP-1 and exendin-4 can reverse hyperlipidicrelated osteopenia. J Endocrinol 209: 203-210.
    • (2011) J Endocrinol , vol.209 , pp. 203-210
    • Nuche-Berenguer, B.1    Lozano, D.2    Gutiérrez-Rojas, I.3
  • 51
    • 77349116804 scopus 로고    scopus 로고
    • Signaling and biological effects of glucagon-like peptide 1 on the differentiation of mesenchymal stem cells from human bone marrow
    • Sanz C, Vázquez P, Blázquez C, Barrio PA, Alvarez M del M, Blaïzquez E, 2010 Signaling and biological effects of glucagon-like peptide 1 on the differentiation of mesenchymal stem cells from human bone marrow. Am J Physiol Endocrinol Metab 298: E634-E643.
    • (2010) Am J Physiol Endocrinol Metab , vol.298
    • Sanz, C.1    Vázquez, P.2    Blázquez, C.3    Barrio, P.A.4    del Alvarez, M.M.5    Blaïzquez, E.6
  • 52
    • 77956496046 scopus 로고    scopus 로고
    • Presence of a functional receptor for GLP-1 in osteoblastic cells, independent of the cAMP-linked GLP-1 receptor
    • Nuche-Berenguer B, Portal-Nuñez S, Moreno P, et al, 2010 Presence of a functional receptor for GLP-1 in osteoblastic cells, independent of the cAMP-linked GLP-1 receptor. J Cell Physiol 225: 585-592.
    • (2010) J Cell Physiol , vol.225 , pp. 585-592
    • Nuche-Berenguer, B.1    Portal-Nuñez, S.2    Moreno, P.3
  • 54
    • 79951870602 scopus 로고    scopus 로고
    • Exenatide treatment did not affect bone mineral density despite body weight reduction in patients with type 2 diabetes
    • Bunck MC, Eliasson B, Corner A, et al, 2011 Exenatide treatment did not affect bone mineral density despite body weight reduction in patients with type 2 diabetes. Diabetes Obes Metab 13: 374-377.
    • (2011) Diabetes Obes Metab , vol.13 , pp. 374-377
    • Bunck, M.C.1    Eliasson, B.2    Corner, A.3
  • 56
    • 33748442464 scopus 로고    scopus 로고
    • Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over 82 weeks in 314 overweight patients with type 2 diabetes
    • Blonde L, Klein EJ, Han J, et al, 2006 Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over 82 weeks in 314 overweight patients with type 2 diabetes. Diabetes Obes Metab 8: 436-447.
    • (2006) Diabetes Obes Metab , vol.8 , pp. 436-447
    • Blonde, L.1    Klein, E.J.2    Han, J.3
  • 58
    • 0942278946 scopus 로고    scopus 로고
    • Reduction of nocturnal rise in bone resorption by subcutaneous GLP-2
    • Henriksen DB, Alexandersen P, Byrjalsen I, et al, 2004 Reduction of nocturnal rise in bone resorption by subcutaneous GLP-2. Bone 34: 140-147.
    • (2004) Bone , vol.34 , pp. 140-147
    • Henriksen, D.B.1    Alexandersen, P.2    Byrjalsen, I.3
  • 59
    • 33846840695 scopus 로고    scopus 로고
    • Disassociation of bone resorption and formation by GLP-2: A 14-day study in healthy postmenopausal women
    • Henriksen DB, Alexandersen P, Hartmann B, et al, 2007 Disassociation of bone resorption and formation by GLP-2: a 14-day study in healthy postmenopausal women. Bone 40: 723-729.
    • (2007) Bone , vol.40 , pp. 723-729
    • Henriksen, D.B.1    Alexandersen, P.2    Hartmann, B.3
  • 60
    • 70349279885 scopus 로고    scopus 로고
    • Four-month treatment with GLP-2 significantly increases hip BMD: A randomized, placebo-controlled, dose-ranging study in postmenopausal women with low BMD
    • Henriksen DB, Alexandersen P, Hartmann B, et al, 2009 Four-month treatment with GLP-2 significantly increases hip BMD: a randomized, placebo-controlled, dose-ranging study in postmenopausal women with low BMD. Bone 45: 833-842.
    • (2009) Bone , vol.45 , pp. 833-842
    • Henriksen, D.B.1    Alexandersen, P.2    Hartmann, B.3
  • 61
    • 84872466358 scopus 로고    scopus 로고
    • Effect of glucagon-like peptide-2 exposure on bone resorption: Effectiveness of high concentration versus prolonged exposure
    • Askov-Hansen C, Jeppesen PB, Lund P, Hartmann B, Holst JJ, Henriksen DB, 2013 Effect of glucagon-like peptide-2 exposure on bone resorption: Effectiveness of high concentration versus prolonged exposure. Regul Pept 181: 4-8.
    • (2013) Regul Pept , vol.181 , pp. 4-8
    • Askov-Hansen, C.1    Jeppesen, P.B.2    Lund, P.3    Hartmann, B.4    Holst, J.J.5    Henriksen, D.B.6
  • 62
    • 84855881643 scopus 로고    scopus 로고
    • Treatment of adult short bowel syndrome patients with teduglutide
    • Nørholk LM, Holst JJ, Jeppesen PB, 2012 Treatment of adult short bowel syndrome patients with teduglutide. Expert Opin Pharmacother 13: 235-243.
    • (2012) Expert Opin Pharmacother , vol.13 , pp. 235-243
    • Nørholk, L.M.1    Holst, J.J.2    Jeppesen, P.B.3
  • 63
    • 84857095236 scopus 로고    scopus 로고
    • Dipeptidyl peptidase-4 inhibitors and bone fractures: A meta-analysis of randomized clinical trials
    • Monami M, Dicembrini I, Antenore A, Mannucci E, 2011 Dipeptidyl peptidase-4 inhibitors and bone fractures: a meta-analysis of randomized clinical trials. Diabetes Care 34: 2474-2476.
    • (2011) Diabetes Care , vol.34 , pp. 2474-2476
    • Monami, M.1    Dicembrini, I.2    Antenore, A.3    Mannucci, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.