Nutrient-induced secretion and metabolic effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1

Proceedings of the Nutrition Society

Volumn 55, Issue 1, 1996, Pages 291-305

  Knapper, J M E ^a   Morgan, L M ^a   Fletcher, J M ^b  

^a UNIVERSITY OF SURREY   (United Kingdom)

^b UNILEVER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GASTRIC INHIBITORY POLYPEPTIDE; GLUCAGON; GLUCAGON LIKE PEPTIDE; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 (7 36)AMIDE; GLUCAGON-LIKE PEPTIDE 1 (7-36)AMIDE; PEPTIDE FRAGMENT;

ADAPTATION; ADIPOSE TISSUE; ANIMAL; CORONARY ARTERY DISEASE; HUMAN; METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PHYSIOLOGY; REVIEW;

ADAPTATION, PHYSIOLOGICAL; ADIPOSE TISSUE; ANIMALS; CORONARY DISEASE; DIABETES MELLITUS, TYPE 2; GASTRIC INHIBITORY POLYPEPTIDE; GLUCAGON; GLUCAGON-LIKE PEPTIDE 1; GLUCAGON-LIKE PEPTIDES; HUMANS; OBESITY; PEPTIDE FRAGMENTS;

EID: 0030093033     PISSN: 00296651     EISSN: None     Source Type: Journal    
DOI: 10.1079/PNS19960030     Document Type: Article

References (82)

1. Anderson, D. K., Ehali, D., Brown, J. C., Tobin, J. D. & Andres, R. (1978). Oral glucose augmentation of insulin secretion. Journal of Clinical Investigation 62, 152-161.
2. Bailey, C. J., Flatt, P. R., Kwasowski, P., Powell, C. J. & Marks, V. (1986). Immunoreactive gastric inhibitory polypeptide and K cell hyperplasia in obese hyperglycaemic (ob/ob) mice fed high fat and high carbohydrate cafeteria diets. Acta Endocrinologica 112, 224-229.
3. Beety, J. M., Ranganath, L., Morgan, L. M., Howland, R., Wright, J. & Marks, V. (1994). Attenuation of plasma GLP-1 responses to oral carbohydrate but not oral fat in obese subjects. Digestive Diseases and Sciences 39, 1809.
4. Bell, G. I., Santerre, R. F. & Mullenbach, G. I. (1983). Hamster preproglucagon contains the sequence of glucagon and two related peptides. Nature 302, 716-718.
5. Bloom, S. R. & Polak, J. M. (1981). Gut Hormones, 2nd ed., pp. 3-18. Edinburgh: Churchill Livingstone.
6. Brown, J. C., Dryburgh, J. R., Ross, S. A. & Dupré, J. (1975). Identification and actions of gastric inhibitory polypeptide. Recent Progress in Hormone Research 31, 487-532.
7. Brunzell, J. D., Miller, N. E., Alaupovic, P., St Hilaire, R. J., Wang, C. S., Sarson, D. L., Bloom, S. R. & Lewis, B. (1983). Familial chylomicronaemia due to a circulating inhibitor of lipoprotein lipase activity. Journal of Lipid Research 24, 12-19.
8. Cleator, I. G. M. & Gourley, R. H. (1975). Release of immunoreactive gastric inhibitory polypeptide (IRGIP) by oral ingestion of food substances. American Journal of Surgery 13, 128-135.
9. Conlon, J. M. (1988). Proglucagon-derived peptides: nomenclature, biosynthetic relationships and physiological roles. Diabetologia 31, 563-566.
10. Creutzfeldt, W. & Ebert, R. (1985). New developments in the incretin concept. Diabetologia 28, 565-573.
11. Creutzfeldt, W., Ebert, R., Williams, B., Frerichs, H. & Brown, J. C. (1978). GIF and insulin in obesity: increased response to stimulation and defective feedback control of serum levels. Diabetologia 14, 15-24.
12. Drucker, D. J., Phillippe, J., Mojsov, S., Chick, W. L. & Habener, J. F. (1987). Glucagon-like peptide 1 stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line. Proceedings of the National Academy of Sciences, USA 84, 3434-3438.
13. Dupré, J., Greenidge, N., McDonald, T. J., Ross, S. A. & Rubinstein, D. (1976). Inhibition of action of glucagon and adipocytes by gastric inhibitory polypeptide. Metabolism 25, 1197-1199.
14. Ebert, R. & Creutzfeldt, W. (1987). Metabolic effects of gastric inhibitory polypeptide. Frontiers in Hormone Research 16, 175-185.
15. Ebert, R., Nauck, N. & Creutzfeldt, W. (1991). Effect of exogenous and endogenous gastric inhibitory polypeptide (GIP) on plasma triglyceride responses in rats. Hormone and Metabolic Research 23, 1197-1199.
16. Eckel, R. H., Fujimoto, W. Y. & Brunzell, J. D. (1979). Gastric inhibitory polypeptide enhanced lipoprotein lipase activity in cultured preadipocytes. Diabetes 28, 1141-1142.
17. Elahi, D., McAloon-Dyke, M., Fukagawa, N. K., Meneilly, G. S., Sclater, A. L., Minaker, K. L., Habener, J. F. & Andersen, D. K. (1994). The insulinotropic actions of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (7-37) in normal and diabetic subjects. Regulatory Peptides 51, 63-74.
18. Elliott, R. M., Morgan, L. M., Tredger, J. A., Deacon, S., Wright, J. & Marks, V. (1993). Glucagon-like peptide-1(7-36)amide and glucose dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: acute post-prandial and 24-h secretion patterns. Journal of Endocrinology 138, 159-166.
19. Ellis, P. R., Roberts, F. G., Low, A. G. & Morgan, L. M. (1995). The effect of high-molecular-weight guar gum on net apparent glucose absorption and net apparent insulin and gastric inhibitory polypeptide production in the growing pig: relationship to rheological changes in jejunal digesta. British Journal of Nutrition 74, 539-556.
20. Falko, J. M., Crockett, S. E., Cataland, S. & Massaferri, E. L. (1975). Gastric inhibitory polypeptide (GIP) stimulated by fat ingestion in man. Journal of Endocrinology and Metabolism 41, 260-265.
21. Fehmann, H.-C., Göke, B., Göke, R., Trautmann, M. E. & Arnold, R. (1990). Synergistic stimulatory effect of glucagon-like peptide-1(7-36)amide and glucose-dependent insulin-releasing polypeptide on the endocrine rat pancreas. FEBS Letters 252, 109-112.
22. Fielding, B. A., Owen, R., Callow, J. & Frayn, K. N. (1995). Origin of the early postprandial triacylglycerol peak. Proceedings of the Nutrition Society 54, 53A.
23. Flatt, P. R., Bailey, C. J., Kwasowski, P., Swanston-Flatt, S. K. & Marks, V. (1983). Abnormalities of GIP in spontaneous syndromes of obesity and diabetes in mice. Diabetes 32, 433-435.
24. Flatt, P. R., Kwasowski, P., Howland, R. J. & Bailey, C. J. (1991). Gastric inhibitory polypeptide and insulin responses to orally administered amino acids in genetically obese hyperglycaemic (ob/ob) mice. Journal of Nutrition 121, 1123-1128.
25. Fukase, N., Igarashi, M., Takahashi, H., Manaka, H., Yamatani, K., Daimon, M., Tominaga, M. & Sasaki, H. (1993). Hypersecretion of truncated glucagon-like peptide-1 and gastric inhibitory polypeptide in obese patients. Diabetic Medicine 10, 44-49.
26. Fukase, N., Takahashi, H., Manaka, H., Igarashi, M., Yamatani, K., Daimon, M., Sugiyama, K., Tominaga, M. & Sasaki, H. (1992). Differences in glucagon-like peptide-1 and GIP responses following sucrose ingestion. Diabetes Research in Clinical Practice 15, 187-195.
27. Göke, R., Cole, T. & Conlon, J. M. (1989). Characterisation of the receptor for glucagon-like peptide-1(7-36)amide on plasma membranes from rat insulinoma-derived cells by covalent cross-linking. Journal of Molecular Endocrinology 2, 93-98.
28. Göke, R. & Conlon, J. M. (1988). Receptors for glucagon-like peptide-1(7-36)amide on rat insulinoma-derived cells. Journal of Endocrinology 116, 357-362.
29. Goldstein, J. L., Ho, Y. K., Brown, M. S., Innerarity, T. L. & Mahley, R. W. (1980). Cholesteryl ester accumulation in macrophages resulting from receptor-mediated uptake and degradation of hypercholesterolemic canine B-very low density lipoproteins. Journal of Biological Chemistry 255, 1839-1848.
30. Groot, P. H. E., van Stiphout, W. A. H. J., Krauss, X. H., Jensen, J., van Tol, A., van Ramshorst, E., Chin-On, S., Hofman, A., Cresswell, S. R. & Hanekes, L. (1991). Postprandial lipoprotein metabolism in normolipidaemic men with and without coronary artery disease. Atherosclerosis and Thrombosis 11, 653-662.
31. Hampton, S. M., Kwasowksi, P., Tan, K., Morgan, L. M. & Marks, V. (1983). Effect of pretreatment with a high fat diet on gastric inhibitory polypeptide and insulin responses to oral triolein and glucose in rats. Diabetologia 24, 278-281.
32. Holst, J. J. (1994). Glucagonlike peptide 1: A newly discovered gastrointestinal hormone. Gastroenterology 107, 1848-1855.
33. Jones, I. R., Obens, D. R., Luzio, S. & Hayes, T. M. (1989). Obesity is associated with increased post-prandial GIP levels which are not reduced by dietary restriction and weight loss. Diabete et Métabolisme 15, 11-22.
34. Jorde, R., Burhol, P. G. & Schultz, T. B. (1983). Fasting and postprandial plasma GIP values in man measured with seven different antisera. Regulatory Peptides 7, 83-94.
35. Jörnvall, H., Carlquist, M., Kwauk, S., Otte, S. C., McIntosh, C. H. S., Brown, J. C. & Mutt, V. (1981). Amino acid sequence and heterogeneity of gastric inhibitory polypeptide (GIP). FEBS Letters 123, 205-210.
36. Karpe, F., Tornvall, P., Olivecrona, T., Steiner, G., Carlson, L. A. & Hamsten, A. (1993). Composition of human low density lipoprotein: effects of postprandial triglyceride-rich lipoproteins, lipoprotein lipase, hepatic lipase and cholesteryl ester transfer protein. Atherosclerosis 98, 33-49.
37. Kervran, A., Randon, J. & Girard, J. R. (1987). Distribution of oxyntomodulin and glucagon in the gastrointestinal tract and the plasma of the rat. Endocrinology 121, 704-713.
38. Knapper, J. M. E., Bailey, C. J. & Flatt, P. R. (1992). Glucagon-like peptide-1(7-36)amide and glucose-dependent insulinotropic polypeptide in the hyperinsulinaemia of obese hyperglycaemic (ob/ob) mice. Proceedings of the Nutrition Society 52, 38A.
39. Knapper, J. M. E., Furlonger, N., Zampelas, A., Jackson, K., Morgan, L., Kafatos, A., Kapsokephalou, M. & Williams, C. M. (1995a). Postprandial triacylglycerol, GIP and insulin responses to a mixed meal in UK and Greek subjects. 2nd International Congress of the International Society for the Study of Fatty Acids and Lipids, p. A47, Bethesda, Maryland.
40. Knapper, J. M. E., Heath, A., Fletcher, J. M., Morgan, L. M. & Marks, V. (1995b). GIP and GLP-1(7-36)amide secretion in response to intraduodenal infusions in pigs. Comparative Biochemistry and Physiology 111C, 445-450.
41. Knapper, J. M. E., Morgan, L. M., Fletcher, J. M. & Marks, V. (1995c). Plasma and intestinal concentrations of GIP and GLP-1(7-36)amide during suckling and after weaning in pigs. Hormone and Metabolic Research 27, 485-490.
42. Knapper, J. M. E., Puddicombe, S. M., Morgan, L. M., Fletcher, J. M. & Marks, V. (1995d). Investigations into the actions of glucose dependent insulinotropic polypeptide and glucagon-like peptide-1(7-36)amide on lipoprotein lipase activity in explants of rat adipose tissue. Journal of Nutrition 125, 183-188.
43. 7-36: A physiological incretin in man. Lancet ii, 1300-1304.
44. 7-36amide from rat intestine. FEBS Letters 242, 167-170.
45. Kwasowski, P., Flatt, P. R., Bailey, C. J. & Marks, V. (1985). Effects of fatty acid chain length and saturation on gastric inhibitory polypeptide release in obese hyperglycaemic (ob/ob) mice. Bioscience Reports 5, 701-705.
46. Lardinois, C. K., Starich, G. H. & Mazzaferri, E. L. (1988). The postprandial response of gastric inhibitory polypeptide to various dietary fats in man. Journal of the American College of Nutrition 7, 241-247.
47. Low, A. G. (1990). Nutritional regulation of gastric secretion, digestion and emptying. Nutrition Research Reviews 3, 229-252.
48. Mentlein, R., Gallwitz, B. & Schmidt, W. E. (1993). Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum. European Journal of Biochemistry 214, 829-835.
49. Merida, E., Delgado, E., Molina, L. M., Villanueva-Penacarillo, M. L. & Valverde, I. (1993). Presence of glucagon and glucagon-like peptide-1(7-36)amide receptors in solubilised membranes of human adipose tissue. Journal of Clinical Endocrinology and Metabolism 77, 1654-1657.
50. Miholic, J., Ørskov, C., Holst, J. J., Kotzer, J. & Meyer, H. J. (1991). Emptying of the gastric substitute, glucagon-like peptide-1 (GLP-1) and reactive hypoglycaemia after total gastrectomy. Digestive Diseases and Sciences 36, 1361-1370.
51. Montrose-Rafizadeh, C., Egan, J. M. & Roth, J. (1994). Incretin hormones regulate glucose-dependent insulin secretion in RIN 1046-38 cells: mechanisms of action. Endocrinology 135, 589-594.
52. Moody, A. J., Thim, L. & Valverde, I. (1984). The isolation and sequencing of human gastric inhibitory polypeptide (GIP). FEBS Letters 172, 142-148.
53. Moore, B., Edie, E. S. & Abram, J. H. (1906). On the treatment of diabetes mellitus by acid extract of duodenal mucous membrane. Biochemical Journal 1, 28-38.
54. Morgan, L. M. (1992). Insulin secretion and the enteroinsular axis. In Nutrient Regulation of Insulin Secretion, pp. 1-22 [P. R. Flatt, editor]. London: The Biochemical Society.
55. Morgan, L. M., Hampton, S. M., Tredger, J. A., Cramb, R. & Marks, V. (1988). Modification of gastric inhibitory polypeptide (GIP) secretion in man by a high-fat diet. British Journal of Nutrition 59, 373-380.
56. Morgan, L. M., Tredger, J. A., Hampton, S. M., Kwasowski, P., Wright, J., Dunn, M. & Marks, V. (1983). Effect of diet upon response to oral fat and glucose in man; modification in control of the enteroinsular axis. Scandinavian Journal of Gastroenterology 18, 99-101.
57. Murphy, M. C., Isherwood, S. G., Sethi, S., Gould, B. J., Wright, J. W., Knapper, J. M. & Williams, C. M. (1995). Postprandial lipid and hormone responses to meals of varying fat contents: modulatory role of lipoprotein lipase? European Journal of Clinical Nutrition 49, 579-588.
58. Murphy, M. C., Zampelas, A., Puddicombe, S. M., Furlonger, N. P., Morgan, L. M. & Williams, C. M. (1993). Pre-translational regulation of the expression of the lipoprotein lipase gene by dietary fatty acids in the rat. British Journal of Nutrition 70, 727-736.
59. Nauck, M. A., Bartels, E., Ørskov, C., Ebert, R. & Creutzfeldt, W. (1993a). Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide-1 (7-36) amide infused at near-physiological insulinotropic and glucose concentrations. Journal of Clinical Endocrinology and Metabolism 76, 912-917.
60. Nauck, M. A., Kleine, N., Ørskov, C., Holst, J. J., Willms, B. & Creutzfeldt, W. (1993b). Normalisation of fasting hyperglycaemia by exogenous GLP-1(7-36)amide in type 2-diabetic patients. Diabetologia 36, 741-744.
61. Oben, J., Morgan, L., Fletcher, J., Flatt, P., Knapper, J. M. & Marks, V. (1992). The role of insulin and GIP in lipid metabolism in obese (ob/ob) mice. Proceedings of the Nutrition Society 51, 188A.
62. Oben, J., Morgan, L. M., Fletcher, J. & Marks, V. (1991). Effect of enteropancreatic hormones, gastric inhibitory polypeptide and glucagon-like peptide-1(7-36)amide on fatty acid synthesis in explants of rat adipose tissue. Journal of Endocrinology 130, 267-272.
63. Ørskov, C., Holst, J. J., Knuhtsen, S., Baldissera, F. G. A., Poulsen, S. S. & Vagn Nielsen, O. (1986). Glucagon-like peptides GLP-1 & GLP-2, predicted products of the glucagon gene are secreted separately from pig small intestine but not pancreas. Endocrinology 119, 1467-1475.
64. Ørskov, C. & Poulssen, S. S. (1991). Glucagonlike peptide-1(7-36)-amide receptors only in islets of Langerhans. Diabetes 40, 1292-1296.
65. Penman, E., Wass, J. A. H., Medback, S., Morgan, L. M., Lewis, J., Besser, G. M. & Rees, L. H. (1981). Response of circulating somatostatin to nutritional stimuli in normal subjects. Gastroenterology 81, 692-699.
66. Ponter, A. A., Salter, D. N., Morgan, L. M. & Flatt, P. R. (1991). The effect of energy source and feeding level on the hormones of the entero-insular axis and plasma glucose in the growing pig. British Journal of Nutrition 66, 187-197.
67. Roberge, J. N. & Brubaker, P. L. (1993). Regulation of intestinal proglucagon-derived peptide secretion by glucose-dependent insulinotropic peptide in a novel enteroendocrine loop. Endocrinology 133, 233-240.
68. Schmidt, W. E., Siegel, E. G. & Creutzfeldt, W. (1985). Glucagon-like peptide-1 but not glucagon-like peptide-2 stimulates insulin release from isolated rat pancreatic islets. Diabetologia 28, 704-707.
69. Service, P. J., Rizza, R. A., Westland, R. E., Hall, L. D., Gerich, J. E. & Go, V. L. W. (1984). Gastric inhibitory polypeptide in obesity and diabetes mellitus. Journal of Clinical Endocrinology and Metabolism 58, 1133-1140.
70. Shima, K., Suda, T., Nishimoto, K. & Yoshimoto, S. (1990). Relationship between molecular structures of sugars and their ability to stimulate the release of glucagon-like peptide-1 from canine ileal loops. Acta Endocrinologica (Copenhagen) 123, 464-470.
71. Solcia, E., Usellini, L., Buffa, R., Rindi, G., Villani, L., Aguzzi, A. & Silini, E. (1989). Endocrine cells producing regulatory peptides. In Experimentia Supplement no. 56, Regulatory Peptides, pp. 220-246 [J. M. Polak, editor]. Berlin: Birkhäuser Verlag.
72. Sykes, S., Morgan, L. M., English, J. & Marks, V. (1980). Evidence for preferential stimulation of gastric inhibitory polypeptide secretion in the rat by actively transported carbohydrates and their analogues. Journal of Endocrinology 85, 201-207.
73. Szecowka, J., Grill, V., Sandberg, E. & Efendic, S. (1982). Effect of GIP on the secretion of insulin and somatostatin and the accumulation of cyclic AMP in vitro in the rat. Acta Endocrinologica 99, 416-421.
74. Thomas, F. B., Shook, D. F., O'Dorisio, T. M., Cataland, S., Mekhjian, H. S., Caldwell, J. H. & Mazzaferri, E. L. (1977). Localisation of gastric inhibitory polypeptide release by intestinal glucose perfusion in man. Gastroenterology 72, 49-54.
75. Thomas, F. B., Sinar, D., Mazzaferri, E. L., Cataland, S., Mekhjian, H. S., Caldwell, J. H. & Fromkes, J. J. (1978). Selective release of gastric inhibitory polypeptide by intraduodenal amino acid perfusion in man. Gastroenterology 74, 1261-1265.
76. Thomson, A. B. R. & Dietschy, J. M. (1981). Intestinal lipid absorption: major extracellular and intracellular events. In Physiology of the Gastrointestinal Tract, vol. 2, pp. 1147-1220 [L. R. Johnson, editor]. New York: Raven Press.
77. Unger, R. H. & Eisentraut, A. M. (1969). Entero-insular axis. Archives of International Medicine 123, 261-266.
78. Usdin, T. B., Mezey, E., Button, D. C., Brownstein, M. J. & Bonner, T. I. (1993). Gastric inhibitory polypeptide receptor, a member of the secretin-vasoactive intestinal peptide receptor family, is widely distributed in peripheral organs and the brain. Endocrinology 133, 2861-2870.
79. Valverde, I., Merida, E., Delgado, E., Trapote, M. A. & Villanueva-Penacarillo, M. L. (1993). Presence and characterisation of glucagon-like peptide-1(7-36)amide receptors in solubilised membranes of rat adipose tissue. Endocrinology 132, 75-79.
80. Varndell, I. M., Bishop, A. E., Sikri, K. L., Uttenthal, L. O., Bloom, S. R. & Polak, J. M. (1985). Localisation of glucagon-like peptide (GLP) immunoreactants in human gut and pancreas using light and electron microscopic immunocytochemistry. Journal of Histocheinistry and Cytochemistry 44, 1080-1086.
81. Wasada, T., McCorkle, K., Harris, V., Kawai, K., Howard, B. & Unger, R. H. (1981). Effect of gastric inhibitory polypeptide on plasma levels of chylomicron triglycerides in dogs. Journal of Clinical Investigation 68, 1106-1107.
82. Willms, B., Ebert, R. & Creutzfeldt, W. (1978). Gastric inhibitory polypeptide (GIP) and insulin in obesity II. Reversal of increased response to stimulation by starvation or food restriction. Diabetologia 14, 379-387.