Octreotide Abolishes the Acute Decrease in Bone Turnover in Response to Oral Glucose

Journal of Clinical Endocrinology and Metabolism

Volumn 88, Issue 10, 2003, Pages 4867-4873

  Clowes, Jackie A ^a   Allen, Heather C ^a   Prentis, Donna M ^a   Eastell, Richard ^a   Blumsohn, Aubrey ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; COLLAGEN TYPE 1; GLUCOSE; INSULIN; OCTREOTIDE; OSTEOCALCIN; PARATHYROID HORMONE; PEPTIDE; PLACEBO; PROCOLLAGEN; SODIUM CHLORIDE;

ADULT; ARTICLE; BONE TURNOVER; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; FEEDING; FEMALE; GASTROINTESTINAL TRACT; GLUCOSE INTAKE; HORMONE SYNTHESIS; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; OSTEOLYSIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE;

ADMINISTRATION, ORAL; ADULT; BLOOD GLUCOSE; BONE AND BONES; CALCIUM; COLLAGEN; COLLAGEN TYPE I; CROSS-OVER STUDIES; DRUG INTERACTIONS; FEMALE; GLUCOSE; HORMONES; HUMANS; INJECTIONS, INTRAVENOUS; INSULIN; MALE; OCTREOTIDE; OSTEOCALCIN; PARATHYROID HORMONE; PEPTIDE FRAGMENTS; PEPTIDES; PROCOLLAGEN; SINGLE-BLIND METHOD;

EID: 0242320390     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2002-021447     Document Type: Article

References (48)

1. Blumsohn A, Herrington K, Hannon RA, Shao P, Eyre DR, Eastell R 1994 The effect of calcium supplementation on the circadian rhythm of bone resorption. J Clin Endocrinol Metab 79:730-735
2. Bjarnason NH, Henriksen EE, Alexandersen P, Christgau S, Henriksen DB, Christiansen C 2002 Mechanism of circadian variation in bone resorption. Bone 30:307-313
3. Clowes JA, Yap TS, Li J, Hoyle N, Blumsohn A, Hannon RA, Eastell R 2002 The effect of feeding on bone turnover markers and its impact on biological variability of measurements. Bone 30:886-890
4. Schlemmer A, Hassager C 1999 Acute fasting diminishes the circadian rhythm of biochemical markers of bone resorption. Eur J Endocrinol 140:332-337
5. Christgau S 2000 Circadian variation in serum CrossLaps concentration is reduced in fasting individuals. Clin Chem 46:431
6. Fraser WD, Logue FC, Christie JP, Cameron DA, O'Reilly DS, Beastall GH 1994 Alteration of the circadian rhythm of intact parathyroid hormone following a 96-hour fast. Clin Endocrinol (Oxf) 40:523-528
7. Ledger GA, Burritt MF, Kao PC, O'Fallon WM, Riggs BL, Khosla S 1995 Role of parathyroid hormone in mediating nocturnal and age-related increases in bone resorption. J Clin Endocrinol Metab 80:3304-3310
8. Clowes JA, Robinson RT, Heller SR, Eastell R, Blumsohn A 2002 Acute changes of bone turnover and parathyroid hormone induced by insulin and glucose: euglycemic and hypoglycemic hyperinsulinemic clamp studies. J Clin Endocrinol Metab 87:3323-3329
9. Tse TF, Clutter WE, Shah SD, Miller JP, Cryer PE 1983 Neuroendocrine responses to glucose ingestion in man. Specificity, temporal relationships, and quantitative aspects. J Clin Invest 72:270-277
10. Lamberts SW 1988 The role of somatostatin in the regulation of anterior pituitary hormone secretion and the use of its analogs in the treatment of human pituitary tumors. Endocr Rev 9:417-436
11. Fuessl HS, Burrin JM, Williams G, Adrian TE, Bloom SR 1987 The effect of a long-acting somatostatin analogue (SMS 201-995) on intermediary metabolism and gut hormones after a test meal in normal subjects. Aliment Pharmacol Ther 1:321-330
12. Austin LA, Heath H, III 1981 Calcitonin: physiology and pathophysiology. N Engl J Med 304:269-278.
13. Cornish J, Callon KE, Lin CQ, Xiao CL, Mulvey TB, Coy DH, Cooper GJ, Reid IR 1998 Dissociation of the effects of amylin on osteoblast proliferation and bone resorption. Am J Physiol 274:E827-E833
14. Cornish J, Callon KE, Bava U, Kamona SA, Cooper GJ, Reid IR 2001 Effects of calcitonin, amylin, and calcitonin gene-related peptide on osteoclast development. Bone 29:162-168
15. Bollag RJ, Zhong Q, Phillips P, Min L, Zhong L, Cameron R, Mulloy AL, Rasmussen H, Qin F, Ding KH, Isales CM 2000 Osteoblast-derived cells express functional glucose-dependent insulinotropic peptide receptors. Endocrinology 141:1228-1235
16. Holloway WR, Collier FM, Aitken CJ, Myers DE, Hodge JM, Malakellis M, Gough TJ, Collier GR, Nicholson GC 2002 Leptin inhibits osteoclast generation. J Bone Miner Res 17:200-209
17. Haderslev KV, Jeppesen PB, Hartmann B, Thulesen J, Sorensen HA, Graff J, Hansen BS, Tofteng F, Poulsen SS, Madsen JL, Holst JJ, Staun M, Mortensen PB 2002 Short-term administration of glucagon-like peptide-2. Effects on bone mineral density and markers of bone turnover in short-bowel patients with no colon. Scand J Gastroenterol 37:392-398
18. Schlemmer A, Hassager C, Alexandersen P, Fledelius C, Pedersen BJ, Kristensen IO, Christiansen C 1997 Circadian variation in bone resorption is not related to serum cortisol. Bone 21:83-88
19. Heshmati HM, Riggs BL, Burritt MF, McAlister CA, Wollan PC, Khosla S 1998 Effects of the circadian variation in serum cortisol on markers of bone turnover and calcium homeostasis in normal postmenopausal women. J Clin Endocrinol Metab 83:751-756
20. Thomas DM, Udagawa N, Hards DK, Quinn JM, Moseley JM, Findlay DM, Best JD 1998 Insulin receptor expression in primary and cultured osteoclast-like cells. Bone 23:181-186
21. Williams JP, Blair HC, McDonald JM, McKenna MA, Jordan SE, Williford J, Hardy RW 1997 Regulation of osteoclastic bone resorption by glucose. Biochem Biophys Res Commun 235:646-651
22. Tse TF, Clutter WE, Shah SD, Cryer PE 1983 Mechanisms of postprandial glucose counterregulation in man. Physiologic roles of glucagon and epinephrine vis-a-vis insulin in the prevention of hypoglycemia late after glucose ingestion. J Clin Invest 72:278-286
23. Coleman RA, Herrmann TS 1999 Nutritional regulation of leptin in humans. Diabetologia 42:639-646
24. Kocian J, Brodan V 1979 Simultaneous correction of Ca deficiency and acidosis in fasting obese patients as a prevention of bone demineralisation. Nutr Metab 23:391-398
25. Muhlbauer RC, Lozano A, Reinli A 2002 Onion and a mixture of vegetables, salads, and herbs affect bone resorption in the rat by a mechanism independent of their base excess. J Bone Miner Res 17:1230-1236
26. Cornish J, Callon KE, King AR, Cooper GJ, Reid IR 1998 Systemic administration of amylin increases bone mass, linear growth, and adiposity in adult male mice. Am J Physiol 275:E694-E699
27. Bollag RJ, Zhong Q, Ding KH, Phillips P, Zhong L, Qin F, Cranford J, Mulloy AL, Cameron R, Isales CM 2001 Glucose-dependent insulinotropic peptide is an integrative hormone with osteotropic effects. Mol Cell Endocrinol 177:35-41
28. Ohlsson C, Bengtsson BA, Isaksson OG, Andreassen TT, Slootweg MC 1998 Growth hormone and bone. Endocr Rev 19:55-79
29. Rajaram S, Baylink DJ, Mohan S 1997 Insulin-like growth factor-binding proteins in serum and other biological fluids: regulation and functions. Endocr Rev 18:801-831
30. Thissen JP, Ketelslegers JM, Underwood LE 1994 Nutritional regulation of the insulin-like growth factors. Endocr Rev 15:80-101
31. Ebeling PR, Butler PC, Eastell R, Rizza RA, Riggs BL 1991 The nocturnal increase in growth hormone is not the cause of the nocturnal increase in serum osteocalcin. J Clin Endocrinol Metab 73:368-372
32. Bruns C, Dietl MM, Palacios JM, Pless J 1990 Identification and characterization of somatostatin receptors in neonatal rat long bones. Biochem J 265: 39-44
33. Mackie EJ, Trechsel U, Bruns C 1990 Somatostatin receptors are restricted to a subpopulation of osteoblast-like cells during endochondral bone formation. Development 110:1233-1239
34. Brundin T 1999 Splanchnic and extrasplanchnic extraction of insulin following oral and intravenous glucose loads. Clin Sci (Lond) 97:429-436
35. Samnegard B, Brundin T 2001 Renal extraction of insulin and C-peptide in man before and after a glucose meal. Clin Physiol 21:164-171
36. Cooper AM, Braatvedt GD, Qamar MI, Brown H, Thomas DM, Halliwell M, Read AE, Corrall RJ 1991 Fasting and post-prandial splanchnic blood flow is reduced by a somatostatin analogue (octreotide) in man. Clin Sci (Colch) 81:169-175
37. Smedsrod B, Johansson S, Pertoft H 1985 Studies in vivo and in vitro on the uptake and degradation of soluble collagen α1(1) chains in rat liver endothelial and Kupffer cells. Biochem J 228:415-424
38. Melick RA, Farrugia W, Heaton CL, Quelch KJ, Scoggins BA, Wark JD 1988 The metabolic clearance rate of osteocalcin in sheep. Calcif Tissue Int 42:185-190
39. Colwell A, Eastell R 1996 The renal clearance of free and conjugated pyridinium cross-links of collagen. J Bone Miner Res 11:1976-1980
40. Reeve J, Hesp R, Wootton R 1976 A new tracer method for the calculation of rates of bone formation and breakdown in osteoporosis and other generalised skeletal disorders. Calcif Tissue Res 22:191-206
41. Sethi R, Kukreja SC, Bowser EN, Hargis GK, Henderson WJ, Williams GA 1983 Effect of meal on serum parathyroid hormone and calcitonin: possible role of secretin. J Clin Endocrinol Metab 56:549-552
42. D'Erasmo E, Pisani D, Ragno A, Raejntroph N, Vecci E, Acca M 1999 Calcium homeostasis during oral glucose load in healthy women. Horm Metab Res 31:271-273
43. Nowicki M, Kokot F, Surdacki A 1998 The influence of hyperinsulinaemia on calcium-phosphate metabolism in renal failure. Nephrol Dial Transplant 13: 2566-2571
44. Reisine T, Bell GI 1995 Molecular biology of somatostatin receptors. Endocr Rev 16:427-442
45. Fredstorp L, Pernow Y, Werner S 1993 The short and long-term effects of octreotide on calcium homeostasis in patients with acromegaly. Clin Endocrinol (Oxf) 39:331-336
46. Scholz D, Schwille PO 1978 Somatostatin and intestinal calcium absorption in man. Metabolism 27:1349-1352
47. Sadler GP, Jones DL, Morgan JM, Neonakis E, Woodhead JS, Wheeler MH 1998 Role of octreotide on release of intact 1-84 parathyroid hormone from human parathyroid cells. Br J Surg 85:1133-1137
48. Li F, Muhlbauer RC 1999 Food fractionation is a powerful tool to increase bone mass in growing rats and to decrease bone loss in aged rats: modulation of the effect by dietary phosphate. J Bone Miner Res 14:1457-1465