Computational and Experimental Insights into the Mechanism of Substrate Recognition and Feedback Inhibition of Protoporphyrinogen Oxidase

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Hao, Ge Fei ^a   Tan, Ying ^a,b   Yang, Sheng Gang ^a   Wang, Zhi Fang ^a,b   Zhan, Chang Guo ^c   Xi, Zhen ^b   Yang, Guang Fu ^a  

^a CENTRAL CHINA NORMAL UNIVERSITY   (China)

^b NANKAI UNIVERSITY   (China)

^c University of Kentucky   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEMATIN; PROTOPORPHYRINOGEN OXIDASE; THIOCTIC ACID;

ARTICLE; BINDING AFFINITY; COMPUTER MODEL; CONFORMATIONAL TRANSITION; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME SUBSTRATE; HYDROGEN BOND; MOLECULAR RECOGNITION; MUTANT; NEGATIVE FEEDBACK;

BIOCATALYSIS; COMPUTER SIMULATION; FEEDBACK, PHYSIOLOGICAL; FLUORESCENCE; HYDROGEN BONDING; KINETICS; MODELS, MOLECULAR; MUTANT PROTEINS; PROTOPORPHYRINOGEN OXIDASE; PROTOPORPHYRINS; SUBSTRATE SPECIFICITY; THERMODYNAMICS; TOBACCO;

EID: 84880723404     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0069198     Document Type: Article

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