The Cell Wall-Associated Mycolactone Polyketide Synthases Are Necessary but Not Sufficient for Mycolactone Biosynthesis

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Porter, Jessica L ^a   Tobias, Nicholas J ^a,c   Pidot, Sacha J ^a,f   Falgner, Steffen ^a   Tuck, Kellie L ^c   Vettiger, Andrea ^d,e   Hong, Hui ^b   Leadlay, Peter F ^b   Stinear, Timothy P ^a,c  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c MONASH UNIVERSITY   (Australia)

^d SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^e UNIVERSITY OF BASEL   (Switzerland)

^f HANS KNÖLL INSTITUTE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LACTONE; MYCOLACTONE; POLYKETIDE SYNTHASE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL CELL WALL; CELL FRACTIONATION; CONTROLLED STUDY; ENZYME ACTIVITY; GENE REARRANGEMENT; GENETIC ENGINEERING; MYCOBACTERIUM MARINUM; MYCOBACTERIUM ULCERANS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; STRUCTURE ANALYSIS;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ANIMALS; BRAIN MAPPING; CASE-CONTROL STUDIES; CELL PHYSIOLOGICAL PHENOMENA; FEMALE; FLUORODEOXYGLUCOSE F18; FOLLOW-UP STUDIES; GLUCOSE; HUMANS; LONGITUDINAL STUDIES; MALE; MICE; MIDDLE AGED; MILD COGNITIVE IMPAIRMENT; NEURAL NETWORKS (COMPUTER); NEUROIMAGING; POSITRON-EMISSION TOMOGRAPHY; RATS;

EID: 84880708925     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0070520     Document Type: Article

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