-
2
-
-
48249125791
-
Malignant gliomas in adults
-
18669428 10.1056/NEJMra0708126 1:CAS:528:DC%2BD1cXpt1Sgsrw%3D
-
Wen PY, Kesari S (2008) Malignant gliomas in adults. N Engl J Med 359:492-507
-
(2008)
N Engl J Med
, vol.359
, pp. 492-507
-
-
Wen, P.Y.1
Kesari, S.2
-
4
-
-
73649088347
-
Mutant metabolic enzymes are at the origin of gliomas
-
19996293 10.1158/0008-5472.CAN-09-2650 1:CAS:528:DC%2BD1MXhsFGrtbrE
-
Yan H, Bigner DD, Velculescu V, Parsons DW (2009) Mutant metabolic enzymes are at the origin of gliomas. Cancer Res 69:9157-9159
-
(2009)
Cancer Res
, vol.69
, pp. 9157-9159
-
-
Yan, H.1
Bigner, D.D.2
Velculescu, V.3
Parsons, D.W.4
-
5
-
-
80052713548
-
Genetic profile of astrocytic and oligodendroglial gliomas
-
21442241 10.1007/s10014-011-0029-1 1:CAS:528:DC%2BC3MXpvVOnt7k%3D
-
Ohgaki H, Kleihues P (2011) Genetic profile of astrocytic and oligodendroglial gliomas. Brain Tumor Pathol 28:177-183
-
(2011)
Brain Tumor Pathol
, vol.28
, pp. 177-183
-
-
Ohgaki, H.1
Kleihues, P.2
-
6
-
-
83355163405
-
Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin
-
22025148 10.1200/JCO.2010.33.8715 1:CAS:528:DC%2BC38XhtlKmtL0%3D
-
Lai A, Kharbanda S, Pope WB et al (2011) Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin. J Clin Oncol 29:4482-4490
-
(2011)
J Clin Oncol
, vol.29
, pp. 4482-4490
-
-
Lai, A.1
Kharbanda, S.2
Pope, W.B.3
-
7
-
-
78651082266
-
Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: Implications for classification of gliomas
-
10.1007/s00401-010-0781-z
-
Hartmann C, Hentschel B, Wick W et al (2011) Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas. Acta Neuropathol 120:707-718
-
(2011)
Acta Neuropathol
, vol.120
, pp. 707-718
-
-
Hartmann, C.1
Hentschel, B.2
Wick, W.3
-
8
-
-
33644820339
-
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
-
16530701 10.1016/j.ccr.2006.02.019 1:CAS:528:DC%2BD28XivFWjtL4%3D
-
Phillips HS, Kharbanda S, Chen R et al (2006) Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 9:157-173
-
(2006)
Cancer Cell
, vol.9
, pp. 157-173
-
-
Phillips, H.S.1
Kharbanda, S.2
Chen, R.3
-
9
-
-
73649123907
-
Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
20129251 10.1016/j.ccr.2009.12.020 1:CAS:528:DC%2BC3cXkvFKgsL4%3D
-
Verhaak RG, Hoadley KA, Purdom E et al (2010) Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 17:98-110
-
(2010)
Cancer Cell
, vol.17
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
-
10
-
-
70849122697
-
Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations
-
19915670 10.1371/journal.pone.0007752
-
Brennan C, Momota H, Hambardzumyan D et al (2009) Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations. PLoS One 4:e7752
-
(2009)
PLoS One
, vol.4
, pp. 7752
-
-
Brennan, C.1
Momota, H.2
Hambardzumyan, D.3
-
11
-
-
77952108366
-
Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma
-
20399149 10.1016/j.ccr.2010.03.017 1:CAS:528:DC%2BC3cXmslKqsr0%3D
-
Noushmehr H, Weisenberger DJ, Diefes K et al (2010) Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell 17:510-522
-
(2010)
Cancer Cell
, vol.17
, pp. 510-522
-
-
Noushmehr, H.1
Weisenberger, D.J.2
Diefes, K.3
-
12
-
-
77954331628
-
High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
-
20555079 10.1093/annonc/mdq187
-
Stupp R, Tonn JC, Brada M, Pentheroudakis G (2010) High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 21(Suppl 5):v190-v193
-
(2010)
Ann Oncol
, vol.21
, Issue.SUPPL. 5
-
-
Stupp, R.1
Tonn, J.C.2
Brada, M.3
Pentheroudakis, G.4
-
13
-
-
65349121788
-
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
-
19269895 10.1016/S1470-2045(09)70025-7 1:CAS:528:DC%2BD1MXlsVKhs74%3D
-
Stupp R, Hegi ME, Mason WP et al (2009) Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 10:459-466
-
(2009)
Lancet Oncol
, vol.10
, pp. 459-466
-
-
Stupp, R.1
Hegi, M.E.2
Mason, W.P.3
-
14
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
CGARN 10.1038/nature07385
-
CGARN (2008) Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455:1061-1068
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
15
-
-
75149195336
-
The transcriptional network for mesenchymal transformation of brain tumours
-
20032975 10.1038/nature08712 1:CAS:528:DC%2BD1MXhs1SktbzP
-
Carro MS, Lim WK, Alvarez MJ et al (2010) The transcriptional network for mesenchymal transformation of brain tumours. Nature 463:318-325
-
(2010)
Nature
, vol.463
, pp. 318-325
-
-
Carro, M.S.1
Lim, W.K.2
Alvarez, M.J.3
-
16
-
-
70350525582
-
STAT3 regulation of glioblastoma pathogenesis
-
19601808 10.2174/156652409788488739
-
de la Iglesia N, Puram SV, Bonni A (2009) STAT3 regulation of glioblastoma pathogenesis. Curr Mol Med 9:580-590
-
(2009)
Curr Mol Med
, vol.9
, pp. 580-590
-
-
De La Iglesia, N.1
Puram, S.V.2
Bonni, A.3
-
17
-
-
49549122025
-
New molecular targets in angiogenic vessels of glioblastoma tumours
-
18684337 10.1017/S1462399408000768
-
Anderson JC, McFarland BC, Gladson CL (2008) New molecular targets in angiogenic vessels of glioblastoma tumours. Expert Rev Mol Med 10:e23
-
(2008)
Expert Rev Mol Med
, vol.10
, pp. 23
-
-
Anderson, J.C.1
McFarland, B.C.2
Gladson, C.L.3
-
18
-
-
56649112857
-
Inhibition of transcription factor STAT5b suppresses proliferation, induces G1 cell cycle arrest and reduces tumor cell invasion in human glioblastoma multiforme cells
-
18793823 10.1016/j.canlet.2008.08.011 1:CAS:528:DC%2BD1cXhsVWnu7jP
-
Liang QC, Xiong H, Zhao ZW et al (2009) Inhibition of transcription factor STAT5b suppresses proliferation, induces G1 cell cycle arrest and reduces tumor cell invasion in human glioblastoma multiforme cells. Cancer Lett 273:164-171
-
(2009)
Cancer Lett
, vol.273
, pp. 164-171
-
-
Liang, Q.C.1
Xiong, H.2
Zhao, Z.W.3
-
19
-
-
37549051685
-
STAT-1 expression in human glioblastoma and peritumoral tissue
-
18225539 1:CAS:528:DC%2BD1cXlslaksw%3D%3D
-
Haybaeck J, Obrist P, Schindler CU, Spizzo G, Doppler W (2007) STAT-1 expression in human glioblastoma and peritumoral tissue. Anticancer Res 27:3829-3835
-
(2007)
Anticancer Res
, vol.27
, pp. 3829-3835
-
-
Haybaeck, J.1
Obrist, P.2
Schindler, C.U.3
Spizzo, G.4
Doppler, W.5
-
20
-
-
0021162349
-
DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1
-
6087160 10.1038/310503a0 1:CAS:528:DyaL2cXltVOqtr0%3D
-
Hemmings HC Jr, Greengard P, Tung HY, Cohen P (1984) DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1. Nature 310:503-505
-
(1984)
Nature
, vol.310
, pp. 503-505
-
-
Hemmings, Jr.H.C.1
Greengard, P.2
Tung, H.Y.3
Cohen, P.4
-
21
-
-
0028345725
-
Expression of mRNAs encoding ARPP-16/19, ARPP-21, and DARPP-32 in human brain tissue
-
8120638 1:CAS:528:DyaK2cXmt1Kqu7o%3D
-
Brene S, Lindefors N, Ehrlich M et al (1994) Expression of mRNAs encoding ARPP-16/19, ARPP-21, and DARPP-32 in human brain tissue. J Neurosci 14:985-998
-
(1994)
J Neurosci
, vol.14
, pp. 985-998
-
-
Brene, S.1
Lindefors, N.2
Ehrlich, M.3
-
22
-
-
1342323630
-
DARPP-32: An integrator of neurotransmission
-
14744247 10.1146/annurev.pharmtox.44.101802.121415 1:CAS:528: DC%2BD2cXhvVCktLw%3D
-
Svenningsson P, Nishi A, Fisone G, Girault JA, Nairn AC, Greengard P (2004) DARPP-32: an integrator of neurotransmission. Annu Rev Pharmacol Toxicol 44:269-296
-
(2004)
Annu Rev Pharmacol Toxicol
, vol.44
, pp. 269-296
-
-
Svenningsson, P.1
Nishi, A.2
Fisone, G.3
Girault, J.A.4
Nairn, A.C.5
Greengard, P.6
-
24
-
-
67650667730
-
Darpp-32 and its truncated variant t-Darpp have antagonistic effects on breast cancer cell growth and herceptin resistance
-
19593441 10.1371/journal.pone.0006220
-
Gu L, Waliany S, Kane SE (2009) Darpp-32 and its truncated variant t-Darpp have antagonistic effects on breast cancer cell growth and herceptin resistance. PLoS One 4:e6220
-
(2009)
PLoS One
, vol.4
, pp. 6220
-
-
Gu, L.1
Waliany, S.2
Kane, S.E.3
-
25
-
-
70350439474
-
Wnt-5a-induced phosphorylation of DARPP-32 inhibits breast cancer cell migration in a CREB-dependent manner
-
19651774 10.1074/jbc.M109.048884 1:CAS:528:DC%2BD1MXhtFyjs7%2FJ
-
Hansen C, Howlin J, Tengholm A et al (2009) Wnt-5a-induced phosphorylation of DARPP-32 inhibits breast cancer cell migration in a CREB-dependent manner. J Biol Chem 284:27533-27543
-
(2009)
J Biol Chem
, vol.284
, pp. 27533-27543
-
-
Hansen, C.1
Howlin, J.2
Tengholm, A.3
-
26
-
-
34147135990
-
AKT and CDK5/p35 mediate brain-derived neurotrophic factor induction of DARPP-32 in medium size spiny neurons in vitro
-
17209049 10.1074/jbc.M606508200 1:CAS:528:DC%2BD2sXitlSrtro%3D
-
Bogush A, Pedrini S, Pelta-Heller J et al (2007) AKT and CDK5/p35 mediate brain-derived neurotrophic factor induction of DARPP-32 in medium size spiny neurons in vitro. J Biol Chem 282:7352-7359
-
(2007)
J Biol Chem
, vol.282
, pp. 7352-7359
-
-
Bogush, A.1
Pedrini, S.2
Pelta-Heller, J.3
-
27
-
-
39049122786
-
T-Darpp promotes cancer cell survival by up-regulation of Bcl2 through Akt-dependent mechanism
-
18199533 10.1158/0008-5472.CAN-07-1580 1:CAS:528:DC%2BD1cXmt1Onsw%3D%3D
-
Belkhiri A, Dar AA, Zaika A, Kelley M, El-Rifai W (2008) t-Darpp promotes cancer cell survival by up-regulation of Bcl2 through Akt-dependent mechanism. Cancer Res 68:395-403
-
(2008)
Cancer Res
, vol.68
, pp. 395-403
-
-
Belkhiri, A.1
Dar, A.A.2
Zaika, A.3
Kelley, M.4
El-Rifai, W.5
-
28
-
-
77950188270
-
Down-regulation of Stat3 decreases invasion activity and induces apoptosis of human glioma cells
-
20069389 10.1007/s12031-009-9323-3 1:CAS:528:DC%2BC3cXit1antLo%3D
-
Chen F, Xu Y, Luo Y et al (2010) Down-regulation of Stat3 decreases invasion activity and induces apoptosis of human glioma cells. J Mol Neurosci 40:353-359
-
(2010)
J Mol Neurosci
, vol.40
, pp. 353-359
-
-
Chen, F.1
Xu, Y.2
Luo, Y.3
-
29
-
-
3042748279
-
Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells
-
13678425 10.1186/1471-2407-3-23
-
Konnikova L, Kotecki M, Kruger MM, Cochran BH (2003) Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells. BMC Cancer 3:23
-
(2003)
BMC Cancer
, vol.3
, pp. 23
-
-
Konnikova, L.1
Kotecki, M.2
Kruger, M.M.3
Cochran, B.H.4
-
30
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
15758009 10.1056/NEJMoa043330 1:CAS:528:DC%2BD2MXit1Wksbk%3D
-
Stupp R, Mason WP, van den Bent MJ et al (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352:987-996
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
-
31
-
-
74549120215
-
Application of RT-PCR in formalin-fixed and paraffin-embedded lung cancer tissues
-
10.1038/aps.2009.178
-
Zhang F, Wang ZM, Liu HY et al (2011) Application of RT-PCR in formalin-fixed and paraffin-embedded lung cancer tissues. Acta Pharmacol Sinica 31:111-117
-
(2011)
Acta Pharmacol Sinica
, vol.31
, pp. 111-117
-
-
Zhang, F.1
Wang, Z.M.2
Liu, H.Y.3
-
32
-
-
77954079119
-
Comparison of gene expression profiling by reverse transcription quantitative PCR between fresh frozen and formalin-fixed, paraffin-embedded breast cancer tissues
-
20569212 10.2144/000113388 1:CAS:528:DC%2BC3MXjtVaqsbg%3D
-
Sanchez-Navarro I, Gamez-Pozo A, Gonzalez-Baron M et al (2010) Comparison of gene expression profiling by reverse transcription quantitative PCR between fresh frozen and formalin-fixed, paraffin-embedded breast cancer tissues. Biotechniques 48:389-397
-
(2010)
Biotechniques
, vol.48
, pp. 389-397
-
-
Sanchez-Navarro, I.1
Gamez-Pozo, A.2
Gonzalez-Baron, M.3
-
33
-
-
34548760880
-
MS-MLPA: An attractive alternative laboratory assay for robust, reliable, and semiquantitative detection of MGMT promoter hypermethylation in gliomas
-
17700563 10.1038/labinvest.3700664 1:CAS:528:DC%2BD2sXhtVCrtLjF
-
Jeuken JW, Cornelissen SJ, Vriezen M et al (2007) MS-MLPA: an attractive alternative laboratory assay for robust, reliable, and semiquantitative detection of MGMT promoter hypermethylation in gliomas. Lab Invest 87:1055-1065
-
(2007)
Lab Invest
, vol.87
, pp. 1055-1065
-
-
Jeuken, J.W.1
Cornelissen, S.J.2
Vriezen, M.3
-
34
-
-
33845370278
-
Activation of STAT3, MAPK, and AKT in malignant astrocytic gliomas: Correlation with EGFR status, tumor grade, and survival
-
17146292 10.1097/01.jnen.0000248549.14962.b2 1:CAS:528: DC%2BD2sXkt1Chtw%3D%3D
-
Mizoguchi M, Betensky RA, Batchelor TT, Bernay DC, Louis DN, Nutt CL (2006) Activation of STAT3, MAPK, and AKT in malignant astrocytic gliomas: correlation with EGFR status, tumor grade, and survival. J Neuropathol Exp Neurol 65:1181-1188
-
(2006)
J Neuropathol Exp Neurol
, vol.65
, pp. 1181-1188
-
-
Mizoguchi, M.1
Betensky, R.A.2
Batchelor, T.T.3
Bernay, D.C.4
Louis, D.N.5
Nutt, C.L.6
-
35
-
-
33845527503
-
Characterization of the 12C4 survivin monoclonal antibody and insight into the expression of survivin in human adult tissues
-
17163847 10.1111/j.1365-2559.2006.02556.x 1:STN:280: DC%2BD28jis1Wltw%3D%3D
-
Spaulding B, Pan D, Ghadersohi A et al (2006) Characterization of the 12C4 survivin monoclonal antibody and insight into the expression of survivin in human adult tissues. Histopathology 49:622-633
-
(2006)
Histopathology
, vol.49
, pp. 622-633
-
-
Spaulding, B.1
Pan, D.2
Ghadersohi, A.3
-
36
-
-
20944436621
-
Prognostic significance of the immunohistochemical index of survivin in glioma: A comparative study with the MIB-1 index
-
15937645 10.1007/s11060-004-2353-3 1:CAS:528:DC%2BD28XltA%3D%3D
-
Uematsu M, Ohsawa I, Aokage T et al (2005) Prognostic significance of the immunohistochemical index of survivin in glioma: a comparative study with the MIB-1 index. J Neurooncol 72:231-238
-
(2005)
J Neurooncol
, vol.72
, pp. 231-238
-
-
Uematsu, M.1
Ohsawa, I.2
Aokage, T.3
-
37
-
-
21344462864
-
No prognostic impact of survivin expression in glioblastoma
-
15843906 10.1007/s00401-005-0992-x 1:CAS:528:DC%2BD2MXltFGqt7g%3D
-
Preusser M, Gelpi E, Matej R et al (2005) No prognostic impact of survivin expression in glioblastoma. Acta Neuropathol 109:534-538
-
(2005)
Acta Neuropathol
, vol.109
, pp. 534-538
-
-
Preusser, M.1
Gelpi, E.2
Matej, R.3
-
38
-
-
33750846321
-
The clinical value of Ki-67/MIB-1 labeling index in human astrocytomas
-
16998593 10.1007/BF02893360
-
Johannessen AL, Torp SH (2006) The clinical value of Ki-67/MIB-1 labeling index in human astrocytomas. Pathol Oncol Res 12:143-147
-
(2006)
Pathol Oncol Res
, vol.12
, pp. 143-147
-
-
Johannessen, A.L.1
Torp, S.H.2
-
39
-
-
66549083540
-
Malignant glioma: ESMO clinical recommendations for diagnosis, treatment and follow-up
-
19454432
-
Stupp R, Roila F (2009) Malignant glioma: ESMO clinical recommendations for diagnosis, treatment and follow-up. Ann Oncol 20(Suppl 4):126-128
-
(2009)
Ann Oncol
, vol.20
, Issue.SUPPL. 4
, pp. 126-128
-
-
Stupp, R.1
Roila, F.2
-
40
-
-
0033335616
-
Stat5-mediated regulation of the human type II 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase gene: Activation by prolactin
-
10406460 10.1210/me.13.7.1084 1:CAS:528:DyaK1MXktFKgsb0%3D
-
Feltus FA, Groner B, Melner MH (1999) Stat5-mediated regulation of the human type II 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase gene: activation by prolactin. Mol Endocrinol 13:1084-1093
-
(1999)
Mol Endocrinol
, vol.13
, pp. 1084-1093
-
-
Feltus, F.A.1
Groner, B.2
Melner, M.H.3
-
41
-
-
0033655613
-
Growth hormone pulse-activated STAT5 signalling: A unique regulatory mechanism governing sexual dimorphism of liver gene expression
-
10752065 10.1002/0470870796.ch5 1:CAS:528:DC%2BD3cXjt1Cqu7g%3D discussion 75-81
-
Waxman DJ (2000) Growth hormone pulse-activated STAT5 signalling: a unique regulatory mechanism governing sexual dimorphism of liver gene expression. Novartis Found Symp 227:61-74, discussion 75-81
-
(2000)
Novartis Found Symp
, vol.227
, pp. 61-74
-
-
Waxman, D.J.1
-
42
-
-
18644370396
-
Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer
-
12244303 10.1038/nm762 1:CAS:528:DC%2BD38XnsVGrt7g%3D
-
Viglietto G, Motti ML, Bruni P et al (2002) Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer. Nat Med 8:1136-1144
-
(2002)
Nat Med
, vol.8
, pp. 1136-1144
-
-
Viglietto, G.1
Motti, M.L.2
Bruni, P.3
-
43
-
-
58149468632
-
Nuclear survivin expression predicts poorer prognosis in glioblastoma
-
18953492 10.1007/s11060-008-9720-4 1:CAS:528:DC%2BD1MXjvFemug%3D%3D
-
Shirai K, Suzuki Y, Oka K et al (2009) Nuclear survivin expression predicts poorer prognosis in glioblastoma. J Neurooncol 91:353-358
-
(2009)
J Neurooncol
, vol.91
, pp. 353-358
-
-
Shirai, K.1
Suzuki, Y.2
Oka, K.3
-
44
-
-
40549127131
-
Survivin expression in glioblastomas correlates with proliferation, but not with apoptosis
-
18383832 1:CAS:528:DC%2BD1cXjslWhtro%3D
-
Mellai M, Caldera V, Patrucco A, Annovazzi L, Schiffer D (2008) Survivin expression in glioblastomas correlates with proliferation, but not with apoptosis. Anticancer Res 28:109-118
-
(2008)
Anticancer Res
, vol.28
, pp. 109-118
-
-
Mellai, M.1
Caldera, V.2
Patrucco, A.3
Annovazzi, L.4
Schiffer, D.5
-
45
-
-
51049123447
-
Signal transducer and activator of transcription-3: A molecular hub for signaling pathways in gliomas
-
18505913 10.1158/1541-7786.MCR-07-2180 1:CAS:528:DC%2BD1cXmt1Ojs7s%3D
-
Brantley EC, Benveniste EN (2008) Signal transducer and activator of transcription-3: a molecular hub for signaling pathways in gliomas. Mol Cancer Res 6:675-684
-
(2008)
Mol Cancer Res
, vol.6
, pp. 675-684
-
-
Brantley, E.C.1
Benveniste, E.N.2
-
46
-
-
84255160601
-
The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma
-
22190458 10.1101/gad.176800.111 1:CAS:528:DC%2BC38Xlsl2nuw%3D%3D
-
Bhat KP, Salazar KL, Balasubramaniyan V et al (2011) The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma. Genes Dev 25:2594-2609
-
(2011)
Genes Dev
, vol.25
, pp. 2594-2609
-
-
Bhat, K.P.1
Salazar, K.L.2
Balasubramaniyan, V.3
-
47
-
-
84860247330
-
The tumor microenvironment strongly impacts master transcriptional regulators and gene expression class of glioblastoma
-
22440258 10.1016/j.ajpath.2012.01.040 1:CAS:528:DC%2BC38XnsF2ktb4%3D
-
Cooper LA, Gutman DA, Chisolm C et al (2012) The tumor microenvironment strongly impacts master transcriptional regulators and gene expression class of glioblastoma. Am J Pathol 180:2108-2119
-
(2012)
Am J Pathol
, vol.180
, pp. 2108-2119
-
-
Cooper, L.A.1
Gutman, D.A.2
Chisolm, C.3
-
48
-
-
84862577827
-
STAT3 inhibition overcomes temozolomide resistance in glioblastoma by downregulating MGMT expression
-
Kohsaka S, Wang L, Yachi K et al. (2012) STAT3 inhibition overcomes temozolomide resistance in glioblastoma by downregulating MGMT expression. Mol Cancer Ther
-
(2012)
Mol Cancer Ther
-
-
Kohsaka, S.1
Wang, L.2
Yachi, K.3
-
49
-
-
58149144782
-
Constitutively activated STAT3 frequently coexpresses with epidermal growth factor receptor in high-grade gliomas and targeting STAT3 sensitizes them to Iressa and alkylators
-
18829483 10.1158/1078-0432.CCR-07-4923 1:CAS:528:DC%2BD1cXhtF2nurrJ
-
Lo HW, Cao X, Zhu H, Ali-Osman F (2008) Constitutively activated STAT3 frequently coexpresses with epidermal growth factor receptor in high-grade gliomas and targeting STAT3 sensitizes them to Iressa and alkylators. Clin Cancer Res 14:6042-6054
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6042-6054
-
-
Lo, H.W.1
Cao, X.2
Zhu, H.3
Ali-Osman, F.4
-
50
-
-
79952386422
-
Analysis of phosphotyrosine signaling in glioblastoma identifies STAT5 as a novel downstream target of DeltaEGFR
-
21214269 10.1021/pr101075e 1:CAS:528:DC%2BC3MXhvVymur8%3D
-
Chumbalkar V, Latha K, Hwang Y et al (2011) Analysis of phosphotyrosine signaling in glioblastoma identifies STAT5 as a novel downstream target of DeltaEGFR. J Proteome Res 10:1343-1352
-
(2011)
J Proteome Res
, vol.10
, pp. 1343-1352
-
-
Chumbalkar, V.1
Latha, K.2
Hwang, Y.3
-
51
-
-
54049111791
-
Astrocytic regulation of human monocytic/microglial activation
-
18832699 1:CAS:528:DC%2BD1cXhtF2hs7fI
-
Kostianovsky AM, Maier LM, Anderson RC, Bruce JN, Anderson DE (2008) Astrocytic regulation of human monocytic/microglial activation. J Immunol 181:5425-5432
-
(2008)
J Immunol
, vol.181
, pp. 5425-5432
-
-
Kostianovsky, A.M.1
Maier, L.M.2
Anderson, R.C.3
Bruce, J.N.4
Anderson, D.E.5
-
52
-
-
45849116295
-
Signal transducer and activator of transcription 5A/B in prostate and breast cancers
-
18508994 10.1677/ERC-08-0013 1:CAS:528:DC%2BD1cXosVGjsrw%3D
-
Tan SH, Nevalainen MT (2008) Signal transducer and activator of transcription 5A/B in prostate and breast cancers. Endocr Relat Cancer 15:367-390
-
(2008)
Endocr Relat Cancer
, vol.15
, pp. 367-390
-
-
Tan, S.H.1
Nevalainen, M.T.2
-
53
-
-
67649619334
-
Reciprocal effects of STAT5 and STAT3 in breast cancer
-
19491198 10.1158/1541-7786.MCR-08-0238 1:CAS:528:DC%2BD1MXns1SktLw%3D
-
Walker SR, Nelson EA, Zou L et al (2009) Reciprocal effects of STAT5 and STAT3 in breast cancer. Mol Cancer Res 7:966-976
-
(2009)
Mol Cancer Res
, vol.7
, pp. 966-976
-
-
Walker, S.R.1
Nelson, E.A.2
Zou, L.3
-
54
-
-
55949130712
-
Striatal progenitors derived from human ES cells mature into DARPP32 neurons in vitro and in quinolinic acid-lesioned rats
-
18922775 10.1073/pnas.0808488105 1:CAS:528:DC%2BD1cXhtleks77L
-
Aubry L, Bugi A, Lefort N, Rousseau F, Peschanski M, Perrier AL (2008) Striatal progenitors derived from human ES cells mature into DARPP32 neurons in vitro and in quinolinic acid-lesioned rats. Proc Natl Acad Sci U S A 105:16707-16712
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 16707-16712
-
-
Aubry, L.1
Bugi, A.2
Lefort, N.3
Rousseau, F.4
Peschanski, M.5
Perrier, A.L.6
-
55
-
-
0141675066
-
Overexpression of the 32-kilodalton dopamine and cyclic adenosine 3′,5′-monophosphate-regulated phosphoprotein in common adenocarcinomas
-
14508844 10.1002/cncr.11654 1:CAS:528:DC%2BD3sXot1Wisrw%3D
-
Beckler A, Moskaluk CA, Zaika A et al (2003) Overexpression of the 32-kilodalton dopamine and cyclic adenosine 3′,5′-monophosphate- regulated phosphoprotein in common adenocarcinomas. Cancer 98:1547-1551
-
(2003)
Cancer
, vol.98
, pp. 1547-1551
-
-
Beckler, A.1
Moskaluk, C.A.2
Zaika, A.3
-
56
-
-
33847644521
-
Glial cells more than support cells?
-
17141551 10.1016/j.biocel.2006.10.022 1:CAS:528:DC%2BD2sXivVShs7g%3D
-
He F, Sun YE (2007) Glial cells more than support cells? Int J Biochem Cell Biol 39:661-665
-
(2007)
Int J Biochem Cell Biol
, vol.39
, pp. 661-665
-
-
He, F.1
Sun, Y.E.2
-
57
-
-
80053936719
-
A molecular screening approach to identify and characterize inhibitors of glioblastoma stem cells
-
21859839 10.1158/1535-7163.MCT-11-0268 1:CAS:528:DC%2BC3MXht1yls77M
-
Visnyei K, Onodera H, Damoiseaux R et al (2011) A molecular screening approach to identify and characterize inhibitors of glioblastoma stem cells. Mol Cancer Ther 10:1818-1828
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 1818-1828
-
-
Visnyei, K.1
Onodera, H.2
Damoiseaux, R.3
-
58
-
-
27544500981
-
Growing roles for the mTOR pathway
-
16226444 10.1016/j.ceb.2005.09.009 1:CAS:528:DC%2BD2MXhtFyksL7F
-
Sarbassov DD, Ali SM, Sabatini DM (2005) Growing roles for the mTOR pathway. Curr Opin Cell Biol 17:596-603
-
(2005)
Curr Opin Cell Biol
, vol.17
, pp. 596-603
-
-
Sarbassov, D.D.1
Ali, S.M.2
Sabatini, D.M.3
-
59
-
-
84555187723
-
Inhibition of PI3K-Akt-mTOR signaling in glioblastoma by mTORC1/2 inhibitors
-
22125077 10.1007/978-1-61779-430-8-22 1:CAS:528:DC%2BC38Xht1WlurrK
-
Fan QW, Weiss WA (2012) Inhibition of PI3K-Akt-mTOR signaling in glioblastoma by mTORC1/2 inhibitors. Methods Mol Biol 821:349-359
-
(2012)
Methods Mol Biol
, vol.821
, pp. 349-359
-
-
Fan, Q.W.1
Weiss, W.A.2
-
60
-
-
33645473862
-
Inhibition of Akt survival pathway by a small-molecule inhibitor in human glioblastoma
-
16546978 10.1158/1535-7163.MCT-05-0453 1:CAS:528:DC%2BD28Xitl2ltLY%3D
-
Koul D, Shen R, Bergh S et al (2006) Inhibition of Akt survival pathway by a small-molecule inhibitor in human glioblastoma. Mol Cancer Ther 5:637-644
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 637-644
-
-
Koul, D.1
Shen, R.2
Bergh, S.3
-
61
-
-
0034532701
-
The ubiquitin-proteasome pathway regulates survivin degradation in a cell cycle-dependent manner
-
11069780 1:CAS:528:DC%2BD3MXotlar
-
Zhao J, Tenev T, Martins LM, Downward J, Lemoine NR (2000) The ubiquitin-proteasome pathway regulates survivin degradation in a cell cycle-dependent manner. J Cell Sci 113(Pt 23):4363-4371
-
(2000)
J Cell Sci
, vol.113
, Issue.PART 23
, pp. 4363-4371
-
-
Zhao, J.1
Tenev, T.2
Martins, L.M.3
Downward, J.4
Lemoine, N.R.5
-
62
-
-
55049089416
-
A portrait of tissue phosphoprotein stability in the clinical tissue procurement process
-
18667411 10.1074/mcp.M700596-MCP200 1:CAS:528:DC%2BD1cXht1Ols7zL
-
Espina V, Edmiston KH, Heiby M et al (2008) A portrait of tissue phosphoprotein stability in the clinical tissue procurement process. Mol Cell Proteomics 7:1998-2018
-
(2008)
Mol Cell Proteomics
, vol.7
, pp. 1998-2018
-
-
Espina, V.1
Edmiston, K.H.2
Heiby, M.3
-
63
-
-
84856728163
-
Individualized targeted therapy for glioblastoma: Fact or fiction?
-
22290256 10.1097/PPO.0b013e318243f6c9 1:CAS:528:DC%2BC38XktFCmtLs%3D
-
Weller M, Stupp R, Hegi M, Wick W (2012) Individualized targeted therapy for glioblastoma: fact or fiction? Cancer J 18:40-44
-
(2012)
Cancer J
, vol.18
, pp. 40-44
-
-
Weller, M.1
Stupp, R.2
Hegi, M.3
Wick, W.4
-
64
-
-
79960851663
-
Why is there a lack of consensus on molecular subgroups of glioblastoma? Understanding the nature of biological and statistical variability in glioblastoma expression data
-
21829433 10.1371/journal.pone.0020826 1:CAS:528:DC%2BC3MXhtVOrt7nK
-
Marko NF, Quackenbush J, Weil RJ (2011) Why is there a lack of consensus on molecular subgroups of glioblastoma? Understanding the nature of biological and statistical variability in glioblastoma expression data. PLoS One 6:e20826
-
(2011)
PLoS One
, vol.6
, pp. 20826
-
-
Marko, N.F.1
Quackenbush, J.2
Weil, R.J.3
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