-
2
-
-
0037050022
-
The failing heart
-
Towbin JA, Bowles NE. 2002. The failing heart. Nature 415:227-233.
-
(2002)
Nature
, vol.415
, pp. 227-233
-
-
Towbin, J.A.1
Bowles, N.E.2
-
3
-
-
77953953091
-
Signal integration through blending, bolstering and bifurcating of intracellular information
-
Pawson CT, Scott JD. 2010. Signal integration through blending, bolstering and bifurcating of intracellular information. Nat. Struct. Mol. Biol. 17:653-658.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 653-658
-
-
Pawson, C.T.1
Scott, J.D.2
-
5
-
-
40649095214
-
Modulation of cardiac function by A-kinase anchoring proteins
-
Diviani D. 2008. Modulation of cardiac function by A-kinase anchoring proteins. Curr. Opin. Pharmacol. 8:166-173.
-
(2008)
Curr. Opin. Pharmacol.
, vol.8
, pp. 166-173
-
-
Diviani, D.1
-
7
-
-
80955137615
-
A-kinase anchoring proteins that regulate cardiac remodeling
-
Carnegie GK, Burmeister BT. 2011. A-kinase anchoring proteins that regulate cardiac remodeling. J. Cardiovasc. Pharmacol. 58:451-458.
-
(2011)
J. Cardiovasc. Pharmacol.
, vol.58
, pp. 451-458
-
-
Carnegie, G..1
Burmeister, B.T.2
-
8
-
-
0035941212
-
AKAP-Lbc anchors protein kinase A and nucleates Galpha 12-selective Rho-mediated stress fiber formation
-
Diviani D, Soderling J, Scott JD. 2001. AKAP-Lbc anchors protein kinase A and nucleates Galpha 12-selective Rho-mediated stress fiber formation. J. Biol. Chem. 276:44247-44257.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 44247-44257
-
-
Diviani, D.1
Soderling, J.2
Scott, J.D.3
-
9
-
-
34547166141
-
The A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates alpha1 adrenergic receptor-induced cardiomyocyte hypertrophy
-
Appert-Collin A, Cotecchia S, Nenniger-Tosato M, Pedrazzini T, Diviani D. 2007. The A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates alpha1 adrenergic receptor-induced cardiomyocyte hypertrophy. Proc. Natl. Acad. Sci. U. S. A. 104:10140-10145.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 10140-10145
-
-
Appert-Collin, A.1
Cotecchia, S.2
Nenniger-Tosato, M.3
Pedrazzini, T.4
Diviani, D.5
-
10
-
-
53949090573
-
AKAP-Lbc mobilizes a cardiac hypertrophy signaling pathway
-
Carnegie GK, Soughayer J, Smith FD, Pedroja BS, Zhang F, Diviani D, Bristow MR, Kunkel MT, Newton AC, Langeberg LK, Scott JD. 2008. AKAP-Lbc mobilizes a cardiac hypertrophy signaling pathway. Mol. Cell 32:169-179.
-
(2008)
Mol. Cell
, vol.32
, pp. 169-179
-
-
Carnegie, G.K.1
Soughayer, J.2
Smith, F.D.3
Pedroja, B.S.4
Zhang, F.5
Diviani, D.6
Bristow, M.R.7
Kunkel, M.T.8
Newton, A.C.9
Langeberg, L.K.10
Scott, J.D.11
-
11
-
-
84865597148
-
The A-kinase-anchoring protein AKAP-Lbc facilitates cardioprotective PKA phosphorylation of HSP20 on Ser(16)
-
Edwards HV, Scott JD, Baillie GS. 2012. The A-kinase-anchoring protein AKAP-Lbc facilitates cardioprotective PKA phosphorylation of HSP20 on Ser(16). Biochem. J. 446:437-443
-
(2012)
Biochem J.
, vol.446
, pp. 437-443
-
-
Edwards, H.V.1
Scott, J.D.2
Baillie, G.S.3
-
12
-
-
84871910829
-
AKAP-Lbc anchors IKKbeta to support interleukin-6-mediated cardiomyocyte hypertrophy
-
del Vescovo CD, Cotecchia S, Diviani D. 2013. AKAP-Lbc anchors IKKbeta to support interleukin-6-mediated cardiomyocyte hypertrophy. Mol. Cell Biol. 33:14-27.
-
(2013)
Mol. Cell Biol.
, vol.33
, pp. 14-27
-
-
del Vescovo, C.D.1
Cotecchia, S.2
Diviani, D.3
-
13
-
-
79953141982
-
A-kinase anchoring protein (AKAP)-Lbc anchors a PKN-based signaling complex involved in alpha1-adrenergic receptor-induced p38 activation
-
Cariolato L, Cavin S, Diviani D. 2011. A-kinase anchoring protein (AKAP)-Lbc anchors a PKN-based signaling complex involved in alpha1-adrenergic receptor-induced p38 activation. J. Biol. Chem. 286:7925-7937.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 7925-7937
-
-
Cariolato, L.1
Cavin, S.2
Diviani, D.3
-
14
-
-
77952479238
-
MAPK-activated protein kinase-2 in cardiac hypertrophy and cyclooxygenase-2 regulation in heart
-
Streicher JM, Ren S, Herschman H, Wang Y. 2010. MAPK-activated protein kinase-2 in cardiac hypertrophy and cyclooxygenase-2 regulation in heart. Circ. Res. 106:1434-1443.
-
(2010)
Circ. Res.
, vol.106
, pp. 1434-1443
-
-
Streicher, J.M.1
Ren, S.2
Herschman, H.3
Wang, Y.4
-
15
-
-
80052787378
-
The p38 mitogen-activated protein kinase pathway-a potential target for intervention in infarction, hypertrophy, and heart failure
-
Marber MS, Rose B, Wang Y. 2011. The p38 mitogen-activated protein kinase pathway-a potential target for intervention in infarction, hypertrophy, and heart failure. J. Mol. Cell. Cardiol. 51:485-490.
-
(2011)
J. Mol. Cell. Cardiol.
, vol.51
, pp. 485-490
-
-
Marber, M.S.1
Rose, B.2
Wang, Y.3
-
16
-
-
0030023987
-
Transgenic remodeling of the contractile apparatus in the mammalian heart
-
Palermo J, Gulick J, Colbert M, Fewell J, Robbins J. 1996. Transgenic remodeling of the contractile apparatus in the mammalian heart. Circ. Res. 78:504-509.
-
(1996)
Circ. Res.
, vol.78
, pp. 504-509
-
-
Palermo, J.1
Gulick, J.2
Colbert, M.3
Fewell, J.4
Robbins, J.5
-
17
-
-
0031939753
-
Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family
-
Wang Y, Huang S, Sah VP, Ross J, Jr, Brown JH, Han J, Chien KR. 1998. Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family. J. Biol. Chem. 273:2161-2168.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 2161-2168
-
-
Wang, Y.1
Huang, S.2
Sah, V.P.3
Ross Jr, J.4
Brown, J.H.5
Han, J.6
Chien, K.R.7
-
18
-
-
0035834071
-
The in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardiomyopathy
-
Liao P, Georgakopoulos D, Kovacs A, Zheng M, Lerner D, Pu H, Saffitz J, Chien K, Xiao RP, Kass DA, Wang Y. 2001. The in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardiomyopathy. Proc. Natl. Acad. Sci. U. S. A. 98:12283-12288.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 12283-12288
-
-
Liao, P.1
Georgakopoulos, D.2
Kovacs, A.3
Zheng, M.4
Lerner, D.5
Pu, H.6
Saffitz, J.7
Chien, K.8
Xiao, R.P.9
Kass, D.A.10
Wang, Y.11
-
19
-
-
10044261073
-
p38alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload
-
Nishida K, Yamaguchi O, Hirotani S, Hikoso S, Higuchi Y, Watanabe T, Takeda T, Osuka S, Morita T, Kondoh G, Uno Y, Kashiwase K, Taniike M, Nakai A, Matsumura Y, Miyazaki J, Sudo T, Hongo K, Kusakari Y, Kurihara S, Chien KR, Takeda J, Hori M, Otsu K. 2004. p38alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload. Mol. Cell. Biol. 24:10611-10620.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 10611-10620
-
-
Nishida, K.1
Yamaguchi, O.2
Hirotani, S.3
Hikoso, S.4
Higuchi, Y.5
Watanabe, T.6
Takeda, T.7
Osuka, S.8
Morita, T.9
Kondoh, G.10
Uno, Y.11
Kashiwase, K.12
Taniike, M.13
Nakai, A.14
Matsumura, Y.15
Miyazaki, J.16
Sudo, T.17
Hongo, K.18
Kusakari, Y.19
Kurihara, S.20
Chien, K.R.21
Takeda, J.22
Hori, M.23
Otsu, K.24
more..
-
20
-
-
79953033875
-
Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice
-
Shende P, Plaisance I, Morandi C, Pellieux C, Berthonneche C, Zorzato F, Krishnan J, Lerch R, Hall MN, Ruegg MA, Pedrazzini T, Brink M. 2011. Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice. Circulation 123: 1073-1082.
-
(2011)
Circulation
, vol.123
, pp. 1073-1082
-
-
Shende, P.1
Plaisance, I.2
Morandi, C.3
Pellieux, C.4
Berthonneche, C.5
Zorzato, F.6
Krishnan, J.7
Lerch, R.8
Hall, M.N.9
Ruegg, M.A.10
Pedrazzini, T.11
Brink, M.12
-
21
-
-
77955290360
-
MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice
-
Zhang D, Contu R, Latronico MV, Zhang J, Rizzi R, Catalucci D, Miyamoto S, Huang K, Ceci M, Gu Y, Dalton ND, Peterson KL, Guan KL, Brown JH, Chen J, Sonenberg N, Condorelli G. 2010. MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice. J. Clin. Invest. 120:2805-2816.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 2805-2816
-
-
Zhang, D.1
Contu, R.2
Latronico, M.V.3
Zhang, J.4
Rizzi, R.5
Catalucci, D.6
Miyamoto, S.7
Huang, K.8
Ceci, M.9
Gu, Y.10
Dalton, N.D.11
Peterson, K.L.12
Guan, K.L.13
Brown, J.H.14
Chen, J.15
Sonenberg, N.16
Condorelli, G.17
-
22
-
-
1842579393
-
Hypertrophy of the heart: a new therapeutic target?
-
Frey N, Katus HA, Olson EN, Hill JA. 2004. Hypertrophy of the heart: a new therapeutic target? Circulation 109:1580-1589.
-
(2004)
Circulation
, vol.109
, pp. 1580-1589
-
-
Frey, N.1
Katus, H.A.2
Olson, E.N.3
Hill, J.A.4
-
23
-
-
30544452653
-
The mAKAP complex participates in the induction of cardiac myocyte hypertrophy by adrenergic receptor signaling
-
Pare GC, Bauman AL, McHenry M, Michel JJ, Dodge-Kafka KL, KapiloffMS. 2005. The mAKAP complex participates in the induction of cardiac myocyte hypertrophy by adrenergic receptor signaling. J. Cell Sci. 118:5637-5646.
-
(2005)
J. Cell Sci.
, vol.118
, pp. 5637-5646
-
-
Pare, G.C.1
Bauman, A.L.2
McHenry, M.3
Michel, J.J.4
Dodge-Kafka, K.L.5
Kapiloff, M.S.6
-
24
-
-
25644452031
-
The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways
-
Dodge-Kafka KL, Soughayer J, Pare GC, Carlisle Michel JJ, Langeberg LK, KapiloffMS, Scott JD. 2005. The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways. Nature 437: 574-578.
-
(2005)
Nature
, vol.437
, pp. 574-578
-
-
Dodge-Kafka, K.L.1
Soughayer, J.2
Pare, G.C.3
Carlisle Michel, J.J.4
Langeberg, L.K.5
Kapiloff, M.S.6
Scott, J.D.7
-
25
-
-
74149093368
-
The mAKAPbeta scaffold regulates cardiac myocyte hypertrophy via recruitment of activated calcineurin
-
Li J, Negro A, Lopez J, Bauman AL, Henson E, Dodge-Kafka K, KapiloffMS. 2010. The mAKAPbeta scaffold regulates cardiac myocyte hypertrophy via recruitment of activated calcineurin. J. Mol. Cell. Cardiol. 48:387-394.
-
(2010)
J. Mol. Cell. Cardiol.
, vol.48
, pp. 387-394
-
-
Li, J.1
Negro, A.2
Lopez, J.3
Bauman, A.L.4
Henson, E.5
Dodge-Kafka, K.6
Kapiloff, M.S.7
-
26
-
-
79959572816
-
Phospholipase C epsilon scaffolds to mAKAP and integrates multiple hypertrophic stimuli in cardiac myocytes
-
Zhang L, Malik S, Kelley GG, KapiloffMS, Smrcka AV. 2011. Phospholipase C epsilon scaffolds to mAKAP and integrates multiple hypertrophic stimuli in cardiac myocytes. J. Biol. Chem. 286:23012-23021.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 23012-23021
-
-
Zhang, L.1
Malik, S.2
Kelley, G.G.3
Kapiloff, M.S.4
Smrcka, A.V.5
-
27
-
-
63349098954
-
The A-kinase anchor protein AKAP121 is a negative regulator of cardiomyocyte hypertrophy
-
Abrenica B, AlShaaban M, Czubryt MP. 2009. The A-kinase anchor protein AKAP121 is a negative regulator of cardiomyocyte hypertrophy. J. Mol. Cell. Cardiol. 46:674-681.
-
(2009)
J. Mol. Cell. Cardiol.
, vol.46
, pp. 674-681
-
-
Abrenica, B.1
AlShaaban, M.2
Czubryt, M.P.3
-
28
-
-
78649832811
-
AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade
-
Smith FD, Langeberg LK, Cellurale C, Pawson T, Morrison DK, Davis RJ, Scott JD. 2010. AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade. Nat. Cell Biol. 12:1242-1249.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 1242-1249
-
-
Smith, F.D.1
Langeberg, L.K.2
Cellurale, C.3
Pawson, T.4
Morrison, D.K.5
Davis, R.J.6
Scott, J.D.7
-
29
-
-
77957037945
-
Activation of PKN mediates survival of cardiac myocytes in the heart during ischemia/reperfusion
-
Takagi H, Hsu CP, Kajimoto K, Shao D, Yang Y, Maejima Y, Zhai P, Yehia G, Yamada C, Zablocki D, Sadoshima J. 2010. Activation of PKN mediates survival of cardiac myocytes in the heart during ischemia/reperfusion. Circ. Res. 107:642-649.
-
(2010)
Circ. Res.
, vol.107
, pp. 642-649
-
-
Takagi, H.1
Hsu, C.P.2
Kajimoto, K.3
Shao, D.4
Yang, Y.5
Maejima, Y.6
Zhai, P.7
Yehia, G.8
Yamada, C.9
Zablocki, D.10
Sadoshima, J.11
-
30
-
-
0030749330
-
A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization, and cardiac-specific gene expression
-
Zechner D, Thuerauf DJ, Hanford DS, McDonough PM, Glembotski CC. 1997. A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization, and cardiac-specific gene expression. J. Cell Biol. 139:115-127.
-
(1997)
J. Cell Biol.
, vol.139
, pp. 115-127
-
-
Zechner, D.1
Thuerauf, D.J.2
Hanford, D.S.3
McDonough, P.M.4
Glembotski, C.C.5
-
31
-
-
0035887278
-
Tissue-specific GATA factors are transcriptional effectors of the small GTPase RhoA
-
Charron F, Tsimiklis G, Arcand M, Robitaille L, Liang Q, Molkentin JD, Meloche S, Nemer M. 2001. Tissue-specific GATA factors are transcriptional effectors of the small GTPase RhoA. Genes Dev. 15:2702-2719.
-
(2001)
Genes Dev
, vol.15
, pp. 2702-2719
-
-
Charron, F.1
Tsimiklis, G.2
Arcand, M.3
Robitaille, L.4
Liang, Q.5
Molkentin, J.D.6
Meloche, S.7
Nemer, M.8
-
32
-
-
0038651918
-
Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling
-
Braz JC, Bueno OF, Liang Q, Wilkins BJ, Dai YS, Parsons S, Braunwart J, Glascock BJ, Klevitsky R, Kimball TF, Hewett TE, Molkentin JD. 2003. Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling. J. Clin. Invest. 111:1475-1486.
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 1475-1486
-
-
Braz, J.C.1
Bueno, O.F.2
Liang, Q.3
Wilkins, B.J.4
Dai, Y.S.5
Parsons, S.6
Braunwart, J.7
Glascock, B.J.8
Klevitsky, R.9
Kimball, T.F.10
Hewett, T.E.11
Molkentin, J.D.12
-
33
-
-
85047687695
-
The role of the Grb2-p38 MAPK signaling pathway in cardiac hypertrophy and fibrosis
-
Zhang S, Weinheimer C, Courtois M, Kovacs A, Zhang CE, Cheng AM, Wang Y, Muslin AJ. 2003. The role of the Grb2-p38 MAPK signaling pathway in cardiac hypertrophy and fibrosis. J. Clin. Invest. 111:833-841.
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 833-841
-
-
Zhang, S.1
Weinheimer, C.2
Courtois, M.3
Kovacs, A.4
Zhang, C.E.5
Cheng, A.M.6
Wang, Y.7
Muslin, A.J.8
-
34
-
-
12844256390
-
Overexpression of mitogenactivated protein kinase kinase 6 in the heart improves functional recovery from ischemia in vitro and protects against myocardial infarction in vivo.
-
Martindale JJ, Wall JA, Martinez-Longoria DM, Aryal P, Rockman HA, Guo Y, Bolli R, Glembotski CC. 2005. Overexpression of mitogenactivated protein kinase kinase 6 in the heart improves functional recovery from ischemia in vitro and protects against myocardial infarction in vivo. J. Biol. Chem. 280:669-676.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 669-676
-
-
Martindale, J.J.1
Wall, J.A.2
Martinez-Longoria, D.M.3
Aryal, P.4
Rockman, H.A.5
Guo, Y.6
Bolli, R.7
Glembotski, C.C.8
-
35
-
-
26444459762
-
Cardiomyocyte proliferation: a platform for mammalian cardiac repair
-
Engel FB. 2005. Cardiomyocyte proliferation: a platform for mammalian cardiac repair. Cell Cycle 4:1360-1363.
-
(2005)
Cell Cycle
, vol.4
, pp. 1360-1363
-
-
Engel, F.B.1
-
37
-
-
82555187786
-
A novel cardioprotective p38-MAPK/mTOR pathway
-
Hernandez G, Lal H, Fidalgo M, Guerrero A, Zavilde J, Force T, Pombo CM. 2011. A novel cardioprotective p38-MAPK/mTOR pathway. Exp. Cell Res. 317:2938-2949.
-
(2011)
Exp. Cell Res.
, vol.317
, pp. 2938-2949
-
-
Hernandez, G.1
Lal, H.2
Fidalgo, M.3
Guerrero, A.4
Zavilde, J.5
Force, T.6
Pombo, C.M.7
-
38
-
-
0002537440
-
Cardiac hypertrophy: the good, the bad, and the ugly
-
Frey N, Olson EN. 2003. Cardiac hypertrophy: the good, the bad, and the ugly. Annu. Rev. Physiol. 65:45-79.
-
(2003)
Annu. Rev. Physiol.
, vol.65
, pp. 45-79
-
-
Frey, N.1
Olson, E.N.2
|