Optimizing dimodular nonribosomal peptide synthetases and natural dipeptides in an Escherichia coli heterologous host

Biochemistry and Cell Biology

Volumn 91, Issue 4, 2013, Pages 203-208

  Wyatt, Morgan A ^a,b   Magarvey, Nathan A ^a,b  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

aureusimine; biosynthesis; heterologous expression; nonribosomal peptide; pyrazine

Indexed keywords

AUREUSIMINE; HETEROLOGOUS EXPRESSION; NONRIBOSOMAL PEPTIDE; NONRIBOSOMAL PEPTIDE SYNTHETASES; PHARMACEUTICAL DEVELOPMENT; PRINCIPLE COMPONENT ANALYSIS; PYRAZINES; SINGLE REACTION MONITORING;

AMINO ACIDS; BIOCHEMISTRY; BIOSYNTHESIS; ESCHERICHIA COLI; MACHINERY; PEPTIDES; PRINCIPAL COMPONENT ANALYSIS;

OPTIMIZATION;

DIPEPTIDE; NATURAL PRODUCT; NONRIBOSOMAL PEPTIDE SYNTHETASE; PYRAZINE DERIVATIVE;

ARTICLE; BACTERIUM CULTURE; BIOSYNTHESIS; CONTROLLED STUDY; ESCHERICHIA COLI; EXPRESSION VECTOR; GENE CLUSTER; GENETIC TRANSCRIPTION; HETEROLOGOUS EXPRESSION; NONHUMAN;

DIPEPTIDES; ESCHERICHIA COLI; GENES, BACTERIAL; ISOPROPYL THIOGALACTOSIDE; MAGNETIC RESONANCE SPECTROSCOPY; MULTIGENE FAMILY; PEPTIDE SYNTHASES; PEPTIDES; PRINCIPAL COMPONENT ANALYSIS; PYRAZINES; TEMPERATURE;

EID: 84880681824     PISSN: 08298211     EISSN: 12086002     Source Type: Journal    
DOI: 10.1139/bcb-2012-0097     Document Type: Article

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