-
1
-
-
34547122001
-
The 2007 WHO classification of tumours of the central nervous system
-
Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, et al. (2007) The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 114: 97-109.
-
(2007)
Acta Neuropathol
, vol.114
, pp. 97-109
-
-
Louis, D.N.1
Ohgaki, H.2
Wiestler, O.D.3
Cavenee, W.K.4
Burger, P.C.5
-
2
-
-
56749156414
-
Analysis of the IDH1 codon 132 mutation in brain tumors
-
Balss J, Meyer J, Mueller W, Korshunov A, Hartmann C, et al. (2008) Analysis of the IDH1 codon 132 mutation in brain tumors. Acta Neuropathol 116: 597-602.
-
(2008)
Acta Neuropathol
, vol.116
, pp. 597-602
-
-
Balss, J.1
Meyer, J.2
Mueller, W.3
Korshunov, A.4
Hartmann, C.5
-
3
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
Parsons DW, Jones S, Zhang X, Lin JC, Leary RJ, et al. (2008) An integrated genomic analysis of human glioblastoma multiforme. Science 321: 1807-1812.
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
Lin, J.C.4
Leary, R.J.5
-
4
-
-
60849115270
-
IDH1 and IDH2 mutations in gliomas
-
Yan H, Parsons DW, Jin G, McLendon R, Rasheed BA, et al. (2009) IDH1 and IDH2 mutations in gliomas. N Engl J Med 360: 765-773.
-
(2009)
N Engl J Med
, vol.360
, pp. 765-773
-
-
Yan, H.1
Parsons, D.W.2
Jin, G.3
McLendon, R.4
Rasheed, B.A.5
-
5
-
-
70149093912
-
Recurring mutations found by sequencing an acute myeloid leukemia genome
-
Mardis ER, Ding L, Dooling DJ, Larson DE, McLellan MD, et al. (2009) Recurring mutations found by sequencing an acute myeloid leukemia genome. N Engl J Med 361: 1058-1066.
-
(2009)
N Engl J Med
, vol.361
, pp. 1058-1066
-
-
Mardis, E.R.1
Ding, L.2
Dooling, D.J.3
Larson, D.E.4
McLellan, M.D.5
-
6
-
-
65349150503
-
IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas
-
Watanabe T, Nobusawa S, Kleihues P, Ohgaki H, (2009) IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas. Am J Pathol 174: 1149-1153.
-
(2009)
Am J Pathol
, vol.174
, pp. 1149-1153
-
-
Watanabe, T.1
Nobusawa, S.2
Kleihues, P.3
Ohgaki, H.4
-
7
-
-
77649305610
-
The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate
-
Ward PS, Patel J, Wise DR, Abdel-Wahab O, Bennett BD, et al. (2010) The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Cancer Cell 17: 225-234.
-
(2010)
Cancer Cell
, vol.17
, pp. 225-234
-
-
Ward, P.S.1
Patel, J.2
Wise, D.R.3
Abdel-Wahab, O.4
Bennett, B.D.5
-
8
-
-
69949114447
-
Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas
-
Hartmann C, Meyer J, Balss J, Capper D, Mueller W, et al. (2009) Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas. Acta Neuropathol 118: 469-474.
-
(2009)
Acta Neuropathol
, vol.118
, pp. 469-474
-
-
Hartmann, C.1
Meyer, J.2
Balss, J.3
Capper, D.4
Mueller, W.5
-
9
-
-
0029024462
-
Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase
-
Bolduc JM, Dyer DH, Scott WG, Singer P, Sweet RM, et al. (1995) Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase. Science 268: 1312-1318.
-
(1995)
Science
, vol.268
, pp. 1312-1318
-
-
Bolduc, J.M.1
Dyer, D.H.2
Scott, W.G.3
Singer, P.4
Sweet, R.M.5
-
10
-
-
34547616314
-
Regulation of singlet oxygen-induced apoptosis by cytosolic NADP+-dependent isocitrate dehydrogenase
-
Kim SY, Lee SM, Tak JK, Choi KS, Kwon TK, et al. (2007) Regulation of singlet oxygen-induced apoptosis by cytosolic NADP+-dependent isocitrate dehydrogenase. Mol Cell Biochem 302: 27-34.
-
(2007)
Mol Cell Biochem
, vol.302
, pp. 27-34
-
-
Kim, S.Y.1
Lee, S.M.2
Tak, J.K.3
Choi, K.S.4
Kwon, T.K.5
-
11
-
-
64849098267
-
Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha
-
Zhao S, Lin Y, Xu W, Jiang W, Zha Z, et al. (2009) Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha. Science 324: 261-265.
-
(2009)
Science
, vol.324
, pp. 261-265
-
-
Zhao, S.1
Lin, Y.2
Xu, W.3
Jiang, W.4
Zha, Z.5
-
12
-
-
73349103157
-
Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network
-
Weller M, Felsberg J, Hartmann C, Berger H, Steinbach JP, et al. (2009) Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network. J Clin Oncol 27: 5743-5750.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5743-5750
-
-
Weller, M.1
Felsberg, J.2
Hartmann, C.3
Berger, H.4
Steinbach, J.P.5
-
13
-
-
68349116524
-
IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas
-
Ichimura K, Pearson DM, Kocialkowski S, Backlund LM, Chan R, et al. (2009) IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas. Neuro Oncol 11: 341-347.
-
(2009)
Neuro Oncol
, vol.11
, pp. 341-347
-
-
Ichimura, K.1
Pearson, D.M.2
Kocialkowski, S.3
Backlund, L.M.4
Chan, R.5
-
14
-
-
72049125350
-
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
-
Dang L, White DW, Gross S, Bennett BD, Bittinger MA, et al. (2009) Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 462: 739-744.
-
(2009)
Nature
, vol.462
, pp. 739-744
-
-
Dang, L.1
White, D.W.2
Gross, S.3
Bennett, B.D.4
Bittinger, M.A.5
-
15
-
-
78651463452
-
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of alpha-ketoglutarate-dependent dioxygenases
-
Xu W, Yang H, Liu Y, Yang Y, Wang P, et al. (2011) Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of alpha-ketoglutarate-dependent dioxygenases. Cancer Cell 19: 17-30.
-
(2011)
Cancer Cell
, vol.19
, pp. 17-30
-
-
Xu, W.1
Yang, H.2
Liu, Y.3
Yang, Y.4
Wang, P.5
-
16
-
-
71549126830
-
Intrinsic gene expression profiles of gliomas are a better predictor of survival than histology
-
Gravendeel LA, Kouwenhoven MC, Gevaert O, de Rooi JJ, Stubbs AP, et al. (2009) Intrinsic gene expression profiles of gliomas are a better predictor of survival than histology. Cancer Res 69: 9065-9072.
-
(2009)
Cancer Res
, vol.69
, pp. 9065-9072
-
-
Gravendeel, L.A.1
Kouwenhoven, M.C.2
Gevaert, O.3
de Rooi, J.J.4
Stubbs, A.P.5
-
17
-
-
70349653793
-
IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas
-
Nobusawa S, Watanabe T, Kleihues P, Ohgaki H, (2009) IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas. Clin Cancer Res 15: 6002-6007.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 6002-6007
-
-
Nobusawa, S.1
Watanabe, T.2
Kleihues, P.3
Ohgaki, H.4
-
18
-
-
70249097408
-
Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas
-
Sanson M, Marie Y, Paris S, Idbaih A, Laffaire J, et al. (2009) Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas. J Clin Oncol 27: 4150-4154.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4150-4154
-
-
Sanson, M.1
Marie, Y.2
Paris, S.3
Idbaih, A.4
Laffaire, J.5
-
19
-
-
73349134695
-
NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide
-
Wick W, Hartmann C, Engel C, Stoffels M, Felsberg J, et al. (2009) NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide. J Clin Oncol 27: 5874-5880.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5874-5880
-
-
Wick, W.1
Hartmann, C.2
Engel, C.3
Stoffels, M.4
Felsberg, J.5
-
20
-
-
77953019788
-
The prognostic IDH1(R132) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma
-
Bleeker FE, Atai NA, Lamba S, Jonker A, Rijkeboer D, et al. (2010) The prognostic IDH1(R132) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma. Acta Neuropathol 119: 487-494.
-
(2010)
Acta Neuropathol
, vol.119
, pp. 487-494
-
-
Bleeker, F.E.1
Atai, N.A.2
Lamba, S.3
Jonker, A.4
Rijkeboer, D.5
-
21
-
-
79251470741
-
DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma
-
Christensen BC, Smith AA, Zheng S, Koestler DC, Houseman EA, et al. (2011) DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma. J Natl Cancer Inst 103: 143-153.
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 143-153
-
-
Christensen, B.C.1
Smith, A.A.2
Zheng, S.3
Koestler, D.C.4
Houseman, E.A.5
-
22
-
-
84879540566
-
IDH1/2 gene status defines the prognosis and molecular profiles in patients with grade III gliomas
-
Shibahara I, Sonoda Y, Kanamori M, Saito R, Yamashita Y, et al. (2011) IDH1/2 gene status defines the prognosis and molecular profiles in patients with grade III gliomas. Int J Clin Oncol.
-
(2011)
Int J Clin Oncol
-
-
Shibahara, I.1
Sonoda, Y.2
Kanamori, M.3
Saito, R.4
Yamashita, Y.5
-
23
-
-
84863049390
-
Molecular prognostic factors of anaplastic oligodendroglial tumors and its relationship: a single institutional review of 77 patients from China
-
Li S, Yan C, Huang L, Qiu X, Wang Z, et al. (2012) Molecular prognostic factors of anaplastic oligodendroglial tumors and its relationship: a single institutional review of 77 patients from China. Neuro Oncol 14: 109-116.
-
(2012)
Neuro Oncol
, vol.14
, pp. 109-116
-
-
Li, S.1
Yan, C.2
Huang, L.3
Qiu, X.4
Wang, Z.5
-
24
-
-
84859712831
-
Significance of IDH mutations varies with tumor histology, grade, and genetics in Japanese glioma patients
-
Mukasa A, Takayanagi S, Saito K, Shibahara J, Tabei Y, et al. (2012) Significance of IDH mutations varies with tumor histology, grade, and genetics in Japanese glioma patients. Cancer Sci 103: 587-592.
-
(2012)
Cancer Sci
, vol.103
, pp. 587-592
-
-
Mukasa, A.1
Takayanagi, S.2
Saito, K.3
Shibahara, J.4
Tabei, Y.5
-
25
-
-
84856098344
-
Correlation of IDH1 mutation with clinicopathologic factors and prognosis in primary glioblastoma: a report of 118 patients from China
-
Yan W, Zhang W, You G, Bao Z, Wang Y, et al. (2012) Correlation of IDH1 mutation with clinicopathologic factors and prognosis in primary glioblastoma: a report of 118 patients from China. PLoS ONE 7: e30339.
-
(2012)
PLoS ONE
, vol.7
-
-
Yan, W.1
Zhang, W.2
You, G.3
Bao, Z.4
Wang, Y.5
-
26
-
-
34547450763
-
Practical methods for incorporating summary time-to-event data into meta-analysis
-
Tierney JF, Stewart LA, Ghersi D, Burdett S, Sydes MR, (2007) Practical methods for incorporating summary time-to-event data into meta-analysis. Trials 8: 16.
-
(2007)
Trials
, vol.8
, pp. 16
-
-
Tierney, J.F.1
Stewart, L.A.2
Ghersi, D.3
Burdett, S.4
Sydes, M.R.5
-
27
-
-
0028659004
-
Operating characteristics of a rank correlation test for publication bias
-
Begg CB, Mazumdar M, (1994) Operating characteristics of a rank correlation test for publication bias. Biometrics 50: 1088-1101.
-
(1994)
Biometrics
, vol.50
, pp. 1088-1101
-
-
Begg, C.B.1
Mazumdar, M.2
-
28
-
-
0030922816
-
Bias in meta-analysis detected by a simple, graphical test
-
Egger M, Davey Smith G, Schneider M, Minder C, (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315: 629-634.
-
(1997)
BMJ
, vol.315
, pp. 629-634
-
-
Egger, M.1
Davey Smith, G.2
Schneider, M.3
Minder, C.4
-
29
-
-
77954697566
-
Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism
-
Reitman ZJ, Yan H, (2010) Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism. J Natl Cancer Inst 102: 932-941.
-
(2010)
J Natl Cancer Inst
, vol.102
, pp. 932-941
-
-
Reitman, Z.J.1
Yan, H.2
-
30
-
-
1942469956
-
MGMT: its role in cancer aetiology and cancer therapeutics
-
Gerson SL, (2004) MGMT: its role in cancer aetiology and cancer therapeutics. Nat Rev Cancer 4: 296-307.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 296-307
-
-
Gerson, S.L.1
-
31
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
Hegi ME, Diserens AC, Gorlia T, Hamou MF, de Tribolet N, et al. (2005) MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 352: 997-1003.
-
(2005)
N Engl J Med
, vol.352
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.C.2
Gorlia, T.3
Hamou, M.F.4
de Tribolet, N.5
-
32
-
-
65349121788
-
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
-
Stupp R, Hegi ME, Mason WP, van den Bent MJ, Taphoorn MJ, et al. (2009) Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 10: 459-466.
-
(2009)
Lancet Oncol
, vol.10
, pp. 459-466
-
-
Stupp, R.1
Hegi, M.E.2
Mason, W.P.3
van den Bent, M.J.4
Taphoorn, M.J.5
-
33
-
-
0034626988
-
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
-
Esteller M, Garcia-Foncillas J, Andion E, Goodman SN, Hidalgo OF, et al. (2000) Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 343: 1350-1354.
-
(2000)
N Engl J Med
, vol.343
, pp. 1350-1354
-
-
Esteller, M.1
Garcia-Foncillas, J.2
Andion, E.3
Goodman, S.N.4
Hidalgo, O.F.5
-
34
-
-
19244370208
-
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis
-
Esteller M, Toyota M, Sanchez-Cespedes M, Capella G, Peinado MA, et al. (2000) Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis. Cancer Res 60: 2368-2371.
-
(2000)
Cancer Res
, vol.60
, pp. 2368-2371
-
-
Esteller, M.1
Toyota, M.2
Sanchez-Cespedes, M.3
Capella, G.4
Peinado, M.A.5
-
35
-
-
0035874892
-
Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G: C to A: T transition mutations in p53 in human colorectal tumorigenesis
-
Esteller M, Risques RA, Toyota M, Capella G, Moreno V, et al. (2001) Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G: C to A: T transition mutations in p53 in human colorectal tumorigenesis. Cancer Res 61: 4689-4692.
-
(2001)
Cancer Res
, vol.61
, pp. 4689-4692
-
-
Esteller, M.1
Risques, R.A.2
Toyota, M.3
Capella, G.4
Moreno, V.5
-
36
-
-
34250877865
-
Genetic pathways to primary and secondary glioblastoma
-
Ohgaki H, Kleihues P, (2007) Genetic pathways to primary and secondary glioblastoma. Am J Pathol 170: 1445-1453.
-
(2007)
Am J Pathol
, vol.170
, pp. 1445-1453
-
-
Ohgaki, H.1
Kleihues, P.2
-
37
-
-
28044460103
-
Protein phosphatase activity of PTEN inhibited the invasion of glioma cells with epidermal growth factor receptor mutation type III expression
-
Cai XM, Tao BB, Wang LY, Liang YL, Jin JW, et al. (2005) Protein phosphatase activity of PTEN inhibited the invasion of glioma cells with epidermal growth factor receptor mutation type III expression. Int J Cancer 117: 905-912.
-
(2005)
Int J Cancer
, vol.117
, pp. 905-912
-
-
Cai, X.M.1
Tao, B.B.2
Wang, L.Y.3
Liang, Y.L.4
Jin, J.W.5
-
38
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
Levine AJ, (1997) p53, the cellular gatekeeper for growth and division. Cell 88: 323-331.
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
39
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455: 1061-1068.
-
Nature
, vol.455
, pp. 1061-1068
-
-
-
40
-
-
0028799791
-
Shared allelic losses on chromosomes 1p and 19q suggest a common origin of oligodendroglioma and oligoastrocytoma
-
Kraus JA, Koopmann J, Kaskel P, Maintz D, Brandner S, et al. (1995) Shared allelic losses on chromosomes 1p and 19q suggest a common origin of oligodendroglioma and oligoastrocytoma. J Neuropathol Exp Neurol 54: 91-95.
-
(1995)
J Neuropathol Exp Neurol
, vol.54
, pp. 91-95
-
-
Kraus, J.A.1
Koopmann, J.2
Kaskel, P.3
Maintz, D.4
Brandner, S.5
-
41
-
-
79953287708
-
IDH1 R132H decreases proliferation of glioma cell lines in vitro and in vivo
-
Bralten LB, Kloosterhof NK, Balvers R, Sacchetti A, Lapre L, et al. (2011) IDH1 R132H decreases proliferation of glioma cell lines in vitro and in vivo. Ann Neurol 69: 455-463.
-
(2011)
Ann Neurol
, vol.69
, pp. 455-463
-
-
Bralten, L.B.1
Kloosterhof, N.K.2
Balvers, R.3
Sacchetti, A.4
Lapre, L.5
-
42
-
-
34748858784
-
Oxidative stress and apoptosis: impact on cancer therapy
-
Ozben T, (2007) Oxidative stress and apoptosis: impact on cancer therapy. J Pharm Sci 96: 2181-2196.
-
(2007)
J Pharm Sci
, vol.96
, pp. 2181-2196
-
-
Ozben, T.1
|