Experimental verification of a 4D MLEM reconstruction algorithm used for in-beam PET measurements in particle therapy

Physics in Medicine and Biology

Volumn 58, Issue 15, 2013, Pages 5085-5111

  Stutzer K ^a   Bert, C ^b,e   Enghardt, W ^a,c   Helmbrecht, S ^a   Parodi, K ^d,f   Priegnitz, M ^c   Saito, N ^b   Fiedler, F ^c  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b GSI HELMHOLTZZENTRUM FÜR SCHWERIONENFORSCHUNG GMBH   (Germany)

^c INSTITUTE OF ION BEAM PHYSICS AND MATERIALS RESEARCH   (Germany)

^d UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^e UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^f UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVITY DISTRIBUTION; DELIVERY TECHNIQUES; EXPERIMENTAL VERIFICATION; IN-BEAM POSITRON EMISSION TOMOGRAPHIES; ION-BEAM RADIOTHERAPY; MAXIMUM-LIKELIHOOD EXPECTATION MAXIMIZATIONS; RECONSTRUCTION ALGORITHMS; SYSTEMATIC INVESTIGATIONS;

IMAGE RECONSTRUCTION; POSITRON EMISSION TOMOGRAPHY;

ALGORITHMS;

ALGORITHM; ARTICLE; EQUIPMENT; HUMAN; IMAGE GUIDED RADIOTHERAPY; METHODOLOGY; MOVEMENT (PHYSIOLOGY); POSITRON EMISSION TOMOGRAPHY; ROTATION; THREE DIMENSIONAL IMAGING; DEVICES; PROCEDURES;

ALGORITHMS; HUMANS; IMAGING, THREE-DIMENSIONAL; MOVEMENT; POSITRON-EMISSION TOMOGRAPHY; RADIOTHERAPY, IMAGE-GUIDED; ROTATION;

EID: 84880617991     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/58/15/5085     Document Type: Article

References (48)

1. American Cancer Society 2012 Global Cancer Facts and Figures 2nd edn (Atlanta: American Cancer Society)
2. Bert C and Durante M 2011 Motion in radiotherapy: particle therapy Phys. Med. Biol. 56 R113-44
3. Bert C, Grözinger S O and Rietzel E 2008 Quantification of interplay effects of scanned particle beams and moving targets Phys. Med. Biol. 53 2253-65
4. Bert C, Saito N, Schmidt A, Chaudhri N, Schardt D and Rietzel E 2007 Target motion tracking with a scanned particle beam Med. Phys. 34 4768-71
5. Bühler P, Just U, Will E, Kotzerke J and van den Hoff J 2004 An accurate method for correction of head movement in PET IEEE Trans. Med. Imaging 23 1176-85
6. Chang J Y, Zhang X, Wang X, Kang Y, Riley B, Bilton S, Mohan R, Komaki R and Cox J D 2006 Significant reduction of normal tissue dose by proton radiotherapy compared with three-dimensional conformal or intensity-modulated radiation therapy in stage I or stage III non-small-cell lung cancer Int. J. Radiat. Oncol. Biol. Phys. 65 1087-96
7. Crespo P, Shakirin G and Enghardt W 2006 On the detector arrangement for in-beam PET for hadron therapy monitoring Phys. Med. Biol. 51 2143-63
8. Enghardt W, Crespo P, Fiedler F, Hinz R, Parodi K, Pawelke J and Pönisch F 2004 Charged hadron tumour therapy monitoring by means of PET Nucl. Instrum. Methods Phys. Res. A 525 284-8
9. Enghardt W et al 1992 The spatial distribution of positron-emitting nuclei generated by relativistic light ion beams in organic matter Phys. Med. Biol. 37 2127-31
10. +-activity Acta Oncol. 47 1077-86
11. George R, Chung T D, Vedam S S, Ramakrishnan V, Mohan R, Weiss E and Keall P J 2006 Audio-visual biofeedback for respiratory-gated radiotherapy: impact of audio instruction and audio-visual biofeedback on respiratory-gated radiotherapy Int. J. Radiat. Oncol. Biol. Phys. 65 924-33
12. Helmbrecht S, Santiago A, Enghardt W, Kuess P and Fiedler F 2012 On the feasibility of automatic detection of range deviations from in-beam PET data Phys. Med. Biol. 57 1387-97
13. Hinz R 2000 Beiträge zur Einführung der Positronen-Emissions- Tomographie bei der Schwerionen-Tumortherapie PhD Thesis (Wissenschaftlich- Technischer Bericht FZR-286) Technische Universität Dresden, Germany
14. Jemal A, Bray F, Center M M, Ferlay J, Ward E and Forman D 2011 Global cancer statistics CA Cancer J. Clin. 61 69-90
15. Keall P J et al 2006 The management of respiratory motion in radiation oncology report of AAPM Task Group 76 Med. Phys. 33 3874-900
16. Knopf A, Parodi K, Bortfeld T, Shih H A and Paganetti H 2009 Systematic analysis of biological and physical limitations of proton beam range verification with offline PET/CT scans Phys. Med. Biol. 54 4477-95
17. Kong F M, Ten Haken R K, Schipper M J, Sullivan M A, Chen M, Lopez C, Kalemkerian G P and Hayman J A 2005 High-dose radiation improved local tumor control and overall survival in patients with inoperable/unresectable non-small-cell lung cancer: long-term results of a radiation dose escalation study Int. J. Radiat. Oncol. Biol. Phys. 63 324-33
18. Kuess P, Birkfellner W, Enghardt W, Helmbrecht S, Fiedler F and Georg D 2012 Using statistical measures for automated comparison of in-beam PET data Med. Phys. 39 5874-81
19. Laube K, Menkel S, Bert C, Enghardt W, Helmbrecht S, Saito N and Fiedler F 2013 4D particle therapy PET simulation for moving targets irradiated with scanned ion beams Phys. Med. Biol. 58 513-33
20. Lauckner K 1999 Entwicklung eines iterativen 3D Rekonstruktionsverfahrens für die Kontrolle der Tumorbehandlung mit Schwerionen mittels der Positronen-Emissions-Tomographie PhD Thesis (Wissenschaftlich-Technischer Bericht FZR-264) Technische Universität Dresden, Germany
21. Lee C H, Tait D, Nahum A E and Webb S 1999 Comparison of proton therapy and conformal X-ray therapy in non-small cell lung cancer (NSCLC) Br. J. Radiol. 72 1078-84 (available at http://bjr.birjournals.org/content/72/863/1078. abstract)
22. Li H, Noel C, Garcia-Ramirez J, Low D, Bradley J, Robinson C, Mutic S and Parikh P 2012 Clinical evaluations of an amplitude-based binning algorithm for 4DCT reconstruction in radiation therapy Med. Phys. 39 922-32
23. Li T, Thorndyke B, Schreibmann E, Yang Y and Xing L 2006 Model-based image reconstruction for four-dimensional PET Med. Phys. 33 1288-98
24. Liu H H et al 2007 Assessing respiration-induced tumor motion and internal target volume using four-dimensional computed tomography for radiotherapy of lung cancer Int. J. Radiat. Oncol. Biol. Phys. 68 531-40
25. Lujan A E, Larsen E W, Balter J M and Ten Haken R K 1999 A method for incorporating organ motion due to breathing into 3D dose calculations Med. Phys. 26 715-20
26. Mehta M, Scrimger R, Mackie R, Paliwal B, Chappell R and Fowler J 2001 A new approach to dose escalation in non-small-cell lung cancer Int. J. Radiat. Oncol. Biol. Phys. 49 23-33
27. Minohara S, Kanai T, Endo M, Noda K and Kanazawa M 2000 Respiratory gated irradiation system for heavy-ion radiotherapy Int. J. Radiat. Oncol. Biol. Phys. 47 1097-103
28. Miyamoto T et al 2007 Carbon ion radiotherapy for stage I non-small cell lung cancer using a regimen of four fractions during 1 week J. Thorac. Oncol. 2 916-26
29. Mizuno H et al 2003 Washout measurement of radioisotope implanted by radioactive beams in the rabbit Phys. Med. Biol. 48 2269-81
30. Mori S, Wolfgang J, Lu H M, Schneider R, Choi N C and Chen G T Y 2008 Quantitative assessment of range fluctuations in charged particle lung irradiation Int. J. Radiat. Oncol. Biol. Phys. 70 253-61
31. Nehmeh S A and Erdi Y E 2008 Respiratory motion in positron emission tomography/computed tomography: a review Semin. Nucl. Med. 38 167-76
32. Nishio T, Miyatake A, Ogino T, Nakagawa K, Saijo N and Esumi H 2010 The development and clinical use of a beam on-line PET system mounted on a rotating gantry port in proton therapy Int. J. Radiat. Oncol. Biol. Phys. 76 277-86
33. Parodi K, Saito N, Chaudhri N, Richter C, Durante M, Enghardt W, Rietzel E and Bert C 2009 4D in-beam positron emission tomography for verification of motion-compensated ion beam therapy Med. Phys. 36 4230-43
34. Phillips M H, Pedroni E, Blattmann H, Boehringer T, Coray A and Scheib S 1992 Effects of respiratory motion on dose uniformity with a charged particle scanning method Phys. Med. Biol. 37 223-34
35. Pönisch F, Enghardt W and Lauckner K 2003 Attenuation and scatter correction for in-beam positron emission tomography monitoring of tumour irradiations with heavy ions Phys. Med. Biol. 48 2419-36
36. Qiao F, Pan T, Clark J W Jr and Mawlawi O R 2006 A motion-incorporated reconstruction method for gated PET studies Phys. Med. Biol. 51 3769-83
37. Rietzel E and Bert C 2010 Respiratory motion management in particle therapy Med. Phys. 37 449-60
38. Seppenwoolde Y, Shirato H, Kitamura K, Shimizu S, van Herk M, Lebesque J V and Miyasaka K 2002 Precise and real-time measurement of 3D tumor motion in lung due to breathing and heartbeat, measured during radiotherapy Int. J. Radiat. Oncol. Biol. Phys. 53 822-34
39. Shakirin G, Braess H, Fiedler F, Kunath D, Laube K, Parodi K, Priegnitz M and Enghardt W 2011 Implementation and workflow for PET monitoring of therapeutic ion irradiation: a comparison of in-beam, in-room, and off-line techniques Phys. Med. Biol. 56 1281-98
40. Shirato H, Seppenwoolde Y, Kitamura K, Onimura R and Shimizu S 2004 Intrafractional tumor motion: lung and liver Semin. Radiat. Oncol. 14 10-18
41. Smith J D T 2012 http://tir.astro.utoledo.edu/jdsmith/code/idl.php
42. Sugane T et al 2009 Carbon ion radiotherapy for elderly patients 80 years and older with stage I non-small cell lung cancer Lung Cancer 64 45-50
43. Sutherland I E and Hodgman G W 1974 Reentrant polygon clipping Commun. ACM 17 32-42
44. Thorndyke B, Schreibmann E, Koong A and Xing L 2006 Reducing respiratory motion artifacts in positron emission tomography through retrospective stacking Med. Phys. 33 2632-41
45. Weber U and Kraft G 1999 Design and construction of a ripple filter for a smoothed depth dose distribution in conformal particle therapy Phys. Med. Biol. 44 2765-75
46. Widesott L, Amichetti M and Schwarz M 2008 Proton therapy in lung cancer: clinical outcomes and technical issues. A systematic review Radiother. Oncol. 86 154-64
47. Woo S K, Watabe H, Choi Y, Kim K M, Park C C, Bloomfield P M and Iida H 2004 Sinogram-based motion correction of PET images using optical motion tracking system and list-mode data acquisition IEEE Trans. Nucl. Sci. 51 782-8
48. Yamaya T, Inaniwa T, Minohara S, Yoshida E, Inadama N, Nishikido F, Shibuya K, Lam C F and Murayama H 2008 A proposal of an open PET geometry Phys. Med. Biol. 53 757