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Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 16, 2013, Pages 4602-4607

Synthesis and in vitro antitumor activity of novel iridium(III) complexes with enantiopure C2-symmetrical vicinal diamine ligands

(6) Yang, Qing a Chang, Jun a Song, Jiao a Qian, Meng Ting a Yu, Jian Ming a Sun, Xun a

a FUDAN UNIVERSITY (China)

Author keywords

C 2 Symmetrical; Cytotoxicity; Enantiopure vicinal diamine; Iridium(III) complexes

Indexed keywords

CASPASE 3; DIAMINE DERIVATIVE; DICHLOROBIS[2 DI(4 METHYLPHENYL)ETHANE 1,2 DIAMINE]IRIDIUM CHLORIDE; IRIDIUM COMPLEX; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; OXALIPLATIN; PROTEIN P53; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; ISOMER; OVARY CANCER; PROTEIN CLEAVAGE; REACTION TIME; UPREGULATION; X RAY CRYSTALLOGRAPHY;

C(2)-SYMMETRICAL; CYTOTOXICITY; ENANTIOPURE VICINAL DIAMINE; IRIDIUM(III) COMPLEXES;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; COORDINATION COMPLEXES; CRYSTALLOGRAPHY, X-RAY; DIAMINES; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INHIBITORY CONCENTRATION 50; IRIDIUM; ISOMERISM; LIGANDS;

EID: 84880611371 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2013.06.024 Document Type: Article

Times cited : (11)

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