Dinuclear organoiridium(III) mono- and bis-intercalators with rigid bridging ligands: Synthesis, cytotoxicity and DNA binding

Journal of Inorganic Biochemistry

Volumn 103, Issue 10, 2009, Pages 1405-1414

  Ali Nazif, Mhd ^a   Bangert, Jan Amadé ^a   Ott, Ingo ^b   Gust, Ronald ^c   Stoll, Raphael ^a   Sheldrick, William S ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

^c FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Bis intercalation; Cellular uptake; Cytotoxicity; DNA binding; Iridium; Polypyridyl ligands

Indexed keywords

DINUCLEAR ORGANOIRIDIUM POLYPYRIDYL COMPLEX; DNA; IRIDIUM COMPLEX; UNCLASSIFIED DRUG;

ARTICLE; BASE PAIRING; CELL STRAIN HT29; CELL STRAIN MCF 7; CIRCULAR DICHROISM; COLON CARCINOMA; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DNA BINDING; DRUG SYNTHESIS; DRUG UPTAKE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; INTERCALATION COMPLEX; NUCLEAR OVERHAUSER EFFECT; VISCOSITY;

ANIMALS; CATTLE; CELL LINE, TUMOR; CYTOTOXINS; DNA; HUMANS; INTERCALATING AGENTS; IRIDIUM; ORGANOMETALLIC COMPOUNDS;

EID: 70349410204     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2009.08.003     Document Type: Article

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