Understanding the variability of compound quantification from targeted profiling metabolomics of 1D-1H-NMR spectra in synthetic mixtures and urine with additional insights on choice of pulse sequences and robotic sampling

Metabolomics

Volumn 9, Issue 4, 2013, Pages 887-903

  Sokolenko, Stanislav ^a   McKay, Ryan ^b,d   Blondeel, Eric J M ^a   Lewis, Michael J ^c   Chang, David ^c   George, Ben ^a   Aucoin, Marc G ^a  

^a UNIVERSITY OF WATERLOO   (Canada)

^b National High Field Nuclear Magnetic Resonance Centre (NANUL)   (Canada)

^c Chenomx Inc   (Canada)

^d UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Convolution; Deconvoluting spectra; Error quantification; Metabolomics; Nuclear magnetic resonance NMR; Targeted profiling; Urine

Indexed keywords

GLUCOSE; GLYCINE; MALTOSE; NICOTINE; SUCROSE;

ARTICLE; CONTROLLED STUDY; HUMAN; LIMIT OF DETECTION; LIMIT OF QUANTITATION; MACHINE LEARNING; METABOLOMICS; ONE DIMENSIONAL NUCLEAR OVERHAUSER SPECTROSCOPY; PROCESS OPTIMIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; ROBOTICS; SPECTROSCOPY; URINALYSIS;

EID: 84880606354     PISSN: 15733882     EISSN: 15733890     Source Type: Journal    
DOI: 10.1007/s11306-013-0503-3     Document Type: Article

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