Structure and activity of NADPH-dependent reductase Q1EQE0 from streptomyces kanamyceticus, which catalyses the R-selective reduction of an imine substrate

ChemBioChem

Volumn 14, Issue 11, 2013, Pages 1372-1379

  Rodríguez Mata, María ^a,b   Frank, Annika ^a   Wells, Elizabeth ^a   Leipold, Friedemann ^c   Turner, Nicholas J ^c   Hart, Sam ^a   Turkenburg, Johan P ^a   Grogan, Gideon ^a  

^a UNIVERSITY OF YORK   (United Kingdom)

^b UNIVERSITY OF OVIEDO   (Spain)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Amines; Biocatalysis; Imines; NADPH; Oxidoreductases

Indexed keywords

IMINE; NICOTINAMIDE; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEPENDENT REDUCTASE; UNCLASSIFIED DRUG;

ARTICLE; BIOCATALYST; CATALYSIS; CHEMICAL STRUCTURE; CODON; DIMERIZATION; ENZYME STRUCTURE; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PSEUDOMONAS PUTIDA; REDUCTION; STREPTOMYCES; STREPTOMYCES KANAMYCETICUS; STRUCTURAL HOMOLOGY;

AMINES; BIOCATALYSIS; IMINES; NADPH; OXIDOREDUCTASES;

BACTERIAL PROTEINS; BINDING SITES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; IMINES; KINETICS; NADP; OXIDOREDUCTASES; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; STREPTOMYCES; SUBSTRATE SPECIFICITY;

STREPTOMYCES KANAMYCETICUS;

EID: 84880588738     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.201300321     Document Type: Article

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