(-)-Epigallocatechin-3-gallate blocks nicotine-induced matrix metalloproteinase-9 expression and invasiveness via suppression of NF-κB and AP-1 in endothelial cells

International Journal of Oncology

Volumn 43, Issue 3, 2013, Pages 868-876

  Khoi, Pham Ngoc ^a   Park, Jung Sun ^a   Kim, Jin Hee ^a   Xia, Yong ^a   Kim, Nam Ho ^a   Kim, Kyung Keun ^a   Jung, Young Do ^a  

^a Chonnam National University Medical School   (South Korea)

Author keywords

AP 1; Cell invasion; EGCG; MMP 9; NF B; Nicotine; ROS

Indexed keywords

CATECHIN; EPIGALLOCATECHIN GALLATE; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NICOTINE; REACTIVE OXYGEN METABOLITE;

ARTICLE; CELL INVASION; ENDOTHELIUM CELL; ENZYME ACTIVITY; EXPRESSION VECTOR; HUMAN; HUMAN CELL; ONCOGENE C FOS; ONCOGENE C JUN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TEA;

CATECHIN; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MATRIX METALLOPROTEINASE 9; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NF-KAPPA B; NICOTINE; REACTIVE OXYGEN SPECIES; TRANSCRIPTION FACTOR AP-1;

EID: 84880579559     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2013.2006     Document Type: Article

References (49)

1. Brunnemann KD and Hoffmann D: Analytical studies on tobacco-specific N-nitrosamines in tobacco and tobacco smoke. Crit Rev Toxicol 21: 235-240, 1991.
2. Davis R, Rizwani W, Banerjee S, Kovacs M, Haura E, Coppola D and Chellappan S: Nicotine promotes tumor growth and metastasis in mouse models of lung cancer. PLoS One 4: e7524, 2009.
3. Ji BT, Chow WH, Hsing AW, McLaughlin JK, Dai Q, Gao YT, Blot WJ and Fraumeni JF Jr: Green tea consumption and the risk of pancreatic and colorectal cancers. Int J Cancer 70: 255-258, 1997.
4. Stoner GD and Mukhtar H: Polyphenols as cancer chemopreventive agents. J Cell Biochem (Suppl) 22: 169-180, 1995.
5. Paschka AG, Butler R and Young CY: Induction of apoptosis in prostate cancer cell lines by the green tea component, (-)-epigallocatechin-3-gallate. Cancer Lett 130: 1-7, 1998.
6. Jung YD, Kim MS, Shin BA, Chay KO, Ahn BW, Liu W, Bucana CD, Gallick GE and Ellis LM: EGCG, a major component of green tea, inhibits tumour growth by inhibiting VEGF induction in human colon carcinoma cells. Br J Cancer 84: 844-850, 2001.
7. Sen T, Dutta A and Chatterjee A: Epigallocatechin-3-gallate (EGCG) downregulates gelatinase-B (MMP-9) by involvement of FAK/ERK/NFkappaB and AP-1 in the human breast cancer cell line MDA-MB-231. Anticancer Drugs 21: 632-644, 2010.
8. Kim MH, Jung MA, Hwang YS, Jeong M, Kim SM, Ahn SJ, Shin BA, Ahn BW and Jung YD: Regulation of urokinase plasminogen activator by epigallocatechin-3- gallate in human fibrosarcoma cells. Eur J Pharmacol 487: 1-6, 2004.
9. 2-mediated multiple-signalling pathways. Clin Exp Pharmacol Physiol 30: 88-95, 2003.
10. Jung YD and Ellis LM: Inhibition of tumour invasion and angiogenesis by epigallocatechin gallate (EGCG), a major component of green tea. Int J Exp Pathol 82: 309-316, 2001.
11. Parsons SL, Watson SA, Brown PD, Collins HM and Steele RJ: Matrix metalloproteinases. Br J Surg 84: 160-166, 1997.
12. Chandler S, Miller KM, Clements JM, Lury J, Corkill D, Anthony DC, Adams SE and Gearing AJ: Matrix metalloproteinases, tumor necrosis factor and multiple sclerosis: an overview. J Neuroimmunol 72: 155-161, 1997.
13. Ogata Y, Pratta MA, Nagase H and Arner EC: Matrix metalloproteinase 9 (92-kDa gelatinase/type IV collagenase) is induced in rabbit articular chondrocytes by cotreatment with interleukin 1 beta and a protein kinase C activator. Exp Cell Res 201: 245-249, 1992.
14. Ma Z, Qin H and Benveniste EN: Transcriptional suppression of matrix metalloproteinase-9 gene expression by IFN-gamma and IFN-beta: critical role of STAT-1alpha. J Immunol 167: 5150-5159, 2001.
15. Vartak DG and Gemeinhart RA: Matrix metalloproteases: underutilized targets for drug delivery. J Drug Target 15: 1-20, 2007.
16. Konstantinopoulos PA, Karamouzis MV, Papatsoris AG and Papavassiliou AG: Matrix metalloproteinase inhibitors as anticancer agents. Int J Biochem Cell Biol 40: 1156-1168, 2008.
17. Woodhouse EC, Chuaqui RF and Liotta LA: General mechanisms of metastasis. Cancer 80: 1529-1537, 1997.
18. Mehlen P and Puisieux A: Metastasis: a question of life or death. Nat Rev Cancer 6: 449-458, 2006.
19. Arii S, Mise M, Harada T, Furutani M, Ishigami S, Niwano M, Mizumoto M, Fukumoto M and Imamura M: Overexpression of matrix metalloproteinase 9 gene in hepatocellular carcinoma with invasive potential. Hepatology 24: 316-322, 1996.
20. Klein G, Vellenga E, Fraaije MW, Kamps WA and de Bont ES: The possible role of matrix metalloproteinase (MMP)-2 and MMP-9 in cancer, e.g. acute leukemia. Crit Rev Oncol Hematol 50: 87-100, 2004.
21. Shin SY, Kim JH, Baker A, Lim Y and Lee YH: Transcription factor Egr-1 is essential for maximal matrix metalloproteinase-9 transcription by tumor necrosis factor alpha. Mol Cancer Res 8: 507-519, 2010.
22. McKinsey TA, Brockman JA, Scherer DC, Al-Murrani SW, Green PL and Ballard DW: Inactivation of IkappaBbeta by the tax protein of human T-cell leukemia virus type 1: a potential mechanism for constitutive induction of NF-kappaB. Mol Cell Biol 16: 2083-2090, 1996.
23. Geleziunas R, Ferrell S, Lin X, Mu Y, Cunningham ETJr, Grant M, Connelly MA, Hambor JE, Marcu KB and Greene WC: Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases. Mol Cell Biol 18: 5157-5165, 1998.
24. Hwang YS, Jeong M, Park JS, Kim MH, Lee DB, Shin BA, Mukaida N, Ellis LM, Kim HR, Ahn BW and Jung YD: Interleukin-1beta stimulates IL-8 expression through MAP kinase and ROS signaling in human gastric carcinoma cells. Oncogene 23: 6603-6611, 2004.
25. Kip1 reduces matrix metalloproteinase-9 and inhibits invasion of human breast cancer cells. Anticancer Res 28: 2669-2677, 2008.
26. Poulsen HE, Jensen BR, Weimann A, Jensen SA, Sørensen M and Loft S: Antioxidants, DNA damage and gene expression. Free Radic Res 33: 33-39, 2000.
27. 3) inhibits invasion of HT1080 human fibrosarcoma cells: role of nuclear factor-kappaB and reactive oxygen species. J Cell Bochem 95: 955-969, 2005.
28. Tobar N, Villar V and Santibanez JF: ROS-NFkappaB mediates TGF-beta1-induced expression of urokinase-type plasminogen activator, matrix metalloproteinase-9 and cell invasion. Mol Cell Biochem 340: 195-202, 2010.
29. Kim HS, Kim MH, Jeong M, Hwang YS, Lim SH, Shin BA, Ahn BW and Jung YD: EGCG blocks tumor promoter-induced MMP-9 expression via suppression of MAPK and AP-1 activation in human gastric AGS cells. Anticancer Res 24: 747-753, 2004.
30. Hipskind RA and Bilbe G: MAP kinase signaling cascades and gene expression in osteoblasts. Front Biosci 3: 804-816, 1998.
31. Guedea AL, Schrick C, Guzman YF, Leaderbrand K, Jovasevic V, Corcoran KA, Tronson NC and Radulovic J: ERK-associated changes of AP-1 proteins during fear extinction. Mol Cell Neurosci 47: 137-144, 2011.
32. Iwasaka C, Tanaka K, Abe M and Sato Y: Ets-1 regulates angiogenesis by inducing the expression of urokinase-type plasminogen activator and matrix metalloproteinase-1 and the migration of vascular endothelial cells. J Cell Physiol 169: 522-531, 1996.
33. Hong MH, Kim MH, Chang HJ, Kim NH, Shin BA, Ahn BW and Jung YD: (-)-Epigallocatechin-3-gallate inhibits monocyte chemotactic protein-1 expression in endothelial cells via blocking NF-kappaB signaling. Life Sci 80: 1957-1965, 2007.
34. Wittel UA, Momi N, Seifert G, Wiech T, Hopt UT and Batra SK: The pathobiological impact of cigarette smoke on pancreatic cancer development (Review). Int J Oncol 41: 5-14, 2012.
35. Chen RJ, Chang LW, Lin P and Wang YJ: Epigenetic effects and molecular mechanisms of tumorigenesis induced by cigarette smoke: an overview. J Oncol 2011: 654931, 2011.
36. Jacob-Ferreira AL, Palei AC, Cau SB, Moreno H Jr, Martinez ML, Izidoro-Toledo TC, Gerlach RF and Tanus-Santos JE: Evidence for the involvement of matrix metalloproteinases in the cardiovascular effects produced by nicotine. Eur J Pharmacol 627: 216-222, 2010.
37. Gialeli C, Theocharis AD and Karamanos NK: Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting. FEBS J 278: 16-27, 2011.
38. Noda M, Oh J, Takahashi R, Kondo S, Kitayama H and Takahashi C: RECK: a novel suppressor of malignancy linking oncogenic signaling to extracellular matrix remodeling. Cancer Metastasis Rev 22: 167-175, 2003.
39. Lee HY, Park KS, Kim MK, Lee T, Ryu SH, Woo KJ, Kwon TK and Bae YS: A small compound that inhibits tumor necrosis factor-alpha-induced matrix metalloproteinase-9 upregulation. Biochem Biophys Res Commun 336: 716-722, 2005.
40. 2) increases the steady-state mRNA levels of collagenase/MMP-1 in human dermal fibroblasts. Free Radic Biol Med 22: 515-524, 1997.
41. Asano H, Horinouchi T, Mai Y, Sawada O, Fujii S, Nishiya T, Minami M, Katayama T, Iwanaga T, Terada K and Miwa S: Nicotine- and tar-free cigarette smoke induces cell damage through reactive oxygen species newly generated by PKC-dependent activation of NADPH oxidase. J Pharmacol Sci 118: 275-287, 2012.
42. Okabe S, Suganuma M, Hayashi M, Sueoka E, Komori A and Fujiki H: Mechanisms of growth inhibition of human lung cancer cell line, PC-9, by tea polyphenols. Jpn J Cancer Res 88: 639-643, 1997.
43. Graham HN: Green tea composition, consumption and polyphenol chemistry. Prev Med 21: 334-350, 1992.
44. Zhang G, Miura Y and Yagasaki K: Suppression of adhesion and invasion of hepatoma cells in culture by tea compounds through antioxidative activity. Cancer Lett 159: 169-173, 2000.
45. Sato H and Seiki M: Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells. Oncogene 8: 395-405, 1993.
46. van Dam H and Castellazzi M: Distinct roles of Jun: Fos and Jun: ATF dimers in oncogenesis. Oncogene 20: 2453-2464, 2001.
47. 2-terminal c-Jun phosphorylation in neuronal apoptosis: identification of the nuclear pore complex as a potential target of the JNK pathway. J Cell Biol 170: 401-411, 2005.
48. Gum R, Wang H, Lengyel E, Juarez J and Boyd D: Regulation of 92 kDa type IV collagenase expression by the jun aminoterminal kinase- and the extracellular signal-regulated kinase-dependent signaling cascades. Oncogene 14: 1481-1493, 1997.
49. Simon C, Simon M, Vucelic G, Hicks MJ, Plinkert PK, Koitschev A and Zenner HP: The p38 SAPK pathway regulates the expression of the MMP-9 collagenase via AP-1-dependent promoter activation. Exp Cell Res 271: 344-355, 2001.