메뉴 건너뛰기




Volumn 2, Issue MAY, 2012, Pages

Menin liver-specific hemizygous mice challenged with high fat diet show increased weight gain and markers of metabolic impairment

Author keywords

Fatty liver; Menin; Metabolic syndrome; Type 2 diabetes

Indexed keywords

GLUCAGON; GLUCOKINASE; GLUCOSE; INSULIN; MENIN PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; TRIACYLGLYCEROL; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 2;

EID: 84880552090     PISSN: None     EISSN: 20444052     Source Type: Journal    
DOI: 10.1038/nutd.2012.7     Document Type: Article
Times cited : (7)

References (43)
  • 1
  • 2
    • 83455164000 scopus 로고    scopus 로고
    • Increased prevalence of impaired fasting glucose in MEN1 gene mutation carriers
    • van Wijk JPH, Dreijerink KMA, Pieterman CRC, Lips CJM, Zelissen PMJ, Valk GD. Increased prevalence of impaired fasting glucose in MEN1 gene mutation carriers. Clin Endocrinol 2012; 76: 67-71.
    • (2012) Clin Endocrinol , vol.76 , pp. 67-71
    • Van Wijk Jph1    Kma, D.2    Crc, P.3    Cjm, L.4    Pmj, Z.5    Valk, G.D.6
  • 3
    • 33746084174 scopus 로고    scopus 로고
    • Multiple endocrine neoplasia type 1 (MEN 1) is associated with an increased prevalence of diabetes mellitus and impaired fasting glucose
    • McCallum RW, Parameswaran V, Burgess Jr. Multiple endocrine neoplasia type 1 (MEN 1) is associated with an increased prevalence of diabetes mellitus and impaired fasting glucose. Clin Endocrinol (Oxf) 2006; 65: 163-168.
    • (2006) Clin Endocrinol (Oxf) , vol.65 , pp. 163-168
    • McCallum, R.W.1    Parameswaran, V.2    Burgess, J.R.3
  • 5
    • 56249100986 scopus 로고    scopus 로고
    • A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange
    • Liu Y, Dentin R, Chen D, Hedrick S, Ravnskjaer K, Schenk S et al. A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange. Nature 2008; 456: 269-273.
    • (2008) Nature , vol.456 , pp. 269-273
    • Liu, Y.1    Dentin, R.2    Chen, D.3    Hedrick, S.4    Ravnskjaer, K.5    Schenk, S.6
  • 6
    • 67650242167 scopus 로고    scopus 로고
    • Sensitivity of lipid metabolism and insulin signaling to genetic alterations in hepatic peroxisome proliferator-activated receptor-gamma coactivator-1alpha expression
    • Estall JL, Kahn M, Cooper MP, Fisher FM, Wu MK, Laznik D et al. Sensitivity of lipid metabolism and insulin signaling to genetic alterations in hepatic peroxisome proliferator-activated receptor-gamma coactivator-1alpha expression. Diabetes 2009; 58: 1499-1508.
    • (2009) Diabetes , vol.58 , pp. 1499-1508
    • Estall, J.L.1    Kahn, M.2    Cooper, M.P.3    Fisher, F.M.4    Wu, M.K.5    Laznik, D.6
  • 7
    • 36549069114 scopus 로고    scopus 로고
    • New hepatic targets for glycaemic control in diabetes
    • Agius L. New hepatic targets for glycaemic control in diabetes. Best Pract Res Clin Endocrinol Metab 2007; 21: 587-605.
    • (2007) Best Pract Res Clin Endocrinol Metab , vol.21 , pp. 587-605
    • Agius, L.1
  • 9
    • 20044374023 scopus 로고    scopus 로고
    • Design and validation of a histological scoring system for nonalcoholic fatty liver disease
    • Kleiner DE, Brunt EM, Van Natta M, Behling C, Contos MJ, Cummings OW et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 2005; 41: 1313-1321.
    • (2005) Hepatology , vol.41 , pp. 1313-1321
    • Kleiner, D.E.1    Brunt, E.M.2    Van Natta, M.3    Behling, C.4    Contos, M.J.5    Cummings, O.W.6
  • 10
    • 0024159821 scopus 로고
    • Biological basis of the behavior of sick animals
    • Hart BL. Biological basis of the behavior of sick animals. Neurosci Biobehav Rev 1988; 12: 123-137.
    • (1988) Neurosci Biobehav Rev , vol.12 , pp. 123-137
    • Hart, B.L.1
  • 11
    • 20444396580 scopus 로고    scopus 로고
    • Substantial increases in idarubicin plasma concentration by liposome encapsulation mediates improved antitumor activity
    • Dos Santos N, Waterhouse D, Masin D, Tardi PG, Karlsson G, Edwards K et al. Substantial increases in idarubicin plasma concentration by liposome encapsulation mediates improved antitumor activity. J Control Release 2005; 105: 89-105.
    • (2005) J Control Release , vol.105 , pp. 89-105
    • Dos Santos, N.1    Waterhouse, D.2    Masin, D.3    Tardi, P.G.4    Karlsson, G.5    Edwards, K.6
  • 12
    • 33845881411 scopus 로고    scopus 로고
    • Mechanisms linking obesity to insulin resistance and type 2 diabetes
    • Kahn SE, Hull RL, Utzschneider KM. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 2006; 444: 840-846.
    • (2006) Nature , vol.444 , pp. 840-846
    • Kahn, S.E.1    Hull, R.L.2    Utzschneider, K.M.3
  • 13
    • 17044386953 scopus 로고    scopus 로고
    • Type 2 diabetes: Principles of pathogenesis and therapy
    • Stumvoll M, Goldstein BJ, van Haeften TW. Type 2 diabetes: principles of pathogenesis and therapy. Lancet 2005; 365: 1333-1346.
    • (2005) Lancet , vol.365 , pp. 1333-1346
    • Stumvoll, M.1    Goldstein, B.J.2    Van Haeften, T.W.3
  • 14
    • 0035195538 scopus 로고    scopus 로고
    • Insulin and C-peptide secretion and kinetics in humans: Direct and model-based measurements during OGTT
    • Tura A, Ludvik B, Nolan JJ, Pacini G, Thomaseth K. Insulin and C-peptide secretion and kinetics in humans: direct and model-based measurements during OGTT. Am J Physiol Endocrinol Metab 2001; 281: E966-E974.
    • (2001) Am J Physiol Endocrinol Metab , vol.281
    • Tura, A.1    Ludvik, B.2    Nolan, J.J.3    Pacini, G.4    Thomaseth, K.5
  • 15
    • 34548389205 scopus 로고    scopus 로고
    • Reduction of hepatic insulin clearance after oral glucose ingestion is not mediated by glucagon-like peptide 1 or gastric inhibitory polypeptide in humans
    • Meier JJ, Holst JJ, Schmidt WE, Nauck MA. Reduction of hepatic insulin clearance after oral glucose ingestion is not mediated by glucagon-like peptide 1 or gastric inhibitory polypeptide in humans. Am J Physiol Endocrinol Metab 2007; 293: E849-E856.
    • (2007) Am J Physiol Endocrinol Metab , vol.293
    • Meier, J.J.1    Holst, J.J.2    Schmidt, W.E.3    Nauck, M.A.4
  • 17
    • 68349104492 scopus 로고    scopus 로고
    • Hyperglycemia induced changes in liver: In vivo and in vitro studies
    • Dey A, Chandrasekaran K. Hyperglycemia induced changes in liver: in vivo and in vitro studies. Curr Diabetes Rev 2009; 5: 67-78.
    • (2009) Curr Diabetes Rev , vol.5 , pp. 67-78
    • Dey, A.1    Chandrasekaran, K.2
  • 18
    • 0042767611 scopus 로고    scopus 로고
    • Variation in type 2 diabetes - Related traits in mouse strains susceptible to diet-induced obesity
    • Rossmeisl M, Rim JS, Koza RA, Kozak LP. Variation in type 2 diabetes - related traits in mouse strains susceptible to diet-induced obesity. Diabetes 2003; 52: 1958-1966.
    • (2003) Diabetes , vol.52 , pp. 1958-1966
    • Rossmeisl, M.1    Rim, J.S.2    Koza, R.A.3    Kozak, L.P.4
  • 19
    • 80255131082 scopus 로고    scopus 로고
    • Menin prevents liver steatosis through co-activation of peroxisome proliferator-activated receptor alpha
    • Cheng P, Yang SS, Hu XG, Zhou XY, Zhang YJ, Jin G et al. Menin prevents liver steatosis through co-activation of peroxisome proliferator-activated receptor alpha. FEBS Lett 2011; 585: 3403-3408.
    • (2011) FEBS Lett , vol.585 , pp. 3403-3408
    • Cheng, P.1    Yang, S.S.2    Hu, X.G.3    Zhou, X.Y.4    Zhang, Y.J.5    Jin, G.6
  • 20
    • 36249009634 scopus 로고    scopus 로고
    • Pathology of nonalcoholic fatty liver disease
    • Yeh MM, Brunt EM. Pathology of nonalcoholic fatty liver disease. Am J Clin Pathol 2007; 128: 837-847.
    • (2007) Am J Clin Pathol , vol.128 , pp. 837-847
    • Yeh, M.M.1    Brunt, E.M.2
  • 21
    • 33644547706 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: From steatosis to cirrhosis
    • Farrell GC, Larter CZ. Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology 2006; 43(2 Suppl 1): S99-S112.
    • (2006) Hepatology , vol.43 , Issue.2 SUPPL. 1
    • Farrell, G.C.1    Larter, C.Z.2
  • 22
    • 64749101898 scopus 로고    scopus 로고
    • Benefits and limitations of reducing glucagon action for the treatment of type 2 diabetes
    • Ali S, Drucker DJ. Benefits and limitations of reducing glucagon action for the treatment of type 2 diabetes. Am J Physiol Endocrinol Metab 2009; 296: E415-E421.
    • (2009) Am J Physiol Endocrinol Metab , vol.296
    • Ali, S.1    Drucker, D.J.2
  • 23
    • 57749116021 scopus 로고    scopus 로고
    • A combination of HNF-4 and Foxo1 is required for reciprocal transcriptional regulation of glucokinase and glucose-6-phosphatase genes in response to fasting and feeding
    • Hirota K, Sakamaki J, Ishida J, Shimamoto Y, Nishihara S, Kodama N et al. A combination of HNF-4 and Foxo1 is required for reciprocal transcriptional regulation of glucokinase and glucose-6-phosphatase genes in response to fasting and feeding. J Biol Chem 2008; 283: 32432-32441.
    • (2008) J Biol Chem , vol.283 , pp. 32432-32441
    • Hirota, K.1    Sakamaki, J.2    Ishida, J.3    Shimamoto, Y.4    Nishihara, S.5    Kodama, N.6
  • 24
    • 71449105535 scopus 로고    scopus 로고
    • FoxO1 and HNF-4 are involved in regulation of hepatic glucokinase gene expression by resveratrol
    • Ganjam GK, Dimova EY, Unterman TG, Kietzmann T. FoxO1 and HNF-4 are involved in regulation of hepatic glucokinase gene expression by resveratrol. J Biol Chem 2009; 284: 30783-30797.
    • (2009) J Biol Chem , vol.284 , pp. 30783-30797
    • Ganjam, G.K.1    Dimova, E.Y.2    Unterman, T.G.3    Kietzmann, T.4
  • 25
    • 0036646116 scopus 로고    scopus 로고
    • Activation of glucokinase gene expression by hepatic nuclear factor 4alpha in primary hepatocytes
    • Roth U, Jungermann K, Kietzmann T. Activation of glucokinase gene expression by hepatic nuclear factor 4alpha in primary hepatocytes. Biochem J 2002; 365: 223-228.
    • (2002) Biochem J , vol.365 , pp. 223-228
    • Roth, U.1    Jungermann, K.2    Kietzmann, T.3
  • 26
    • 79960429304 scopus 로고    scopus 로고
    • Gene program-specific regulation of PGC-1a activity
    • Schmidt SF, Mandrup S. Gene program-specific regulation of PGC-1a activity. Genes Dev 2011; 25: 1453-1458.
    • (2011) Genes Dev , vol.25 , pp. 1453-1458
    • Schmidt, S.F.1    Mandrup, S.2
  • 28
    • 51849092965 scopus 로고    scopus 로고
    • Increased hepatic UCP2 expression in rats with nonalcoholic steatohepatitis is associated with upregulation of Sp1 binding to its motif within the proximal promoter region
    • Jiang Y, Zhang H, Dong L-y, Wang D, An W. Increased hepatic UCP2 expression in rats with nonalcoholic steatohepatitis is associated with upregulation of Sp1 binding to its motif within the proximal promoter region. J Cell Biochem 2008; 105: 277-289.
    • (2008) J Cell Biochem , vol.105 , pp. 277-289
    • Jiang, Y.1    Zhang, H.2    Dong, L.-Y.3    Wang, D.4    An, W.5
  • 29
    • 46349087273 scopus 로고    scopus 로고
    • Uncoupling protein-2 (UCP2) induces mitochondrial proton leak and increases susceptibility of non-alcoholic steatohepatitis (NASH) liver to ischaemia-reperfusion injury
    • Serviddio G, Bellanti F, Tamborra R, Rollo T, Capitanio N, Romano AD et al. Uncoupling protein-2 (UCP2) induces mitochondrial proton leak and increases susceptibility of non-alcoholic steatohepatitis (NASH) liver to ischaemia-reperfusion injury. Gut 2008; 57: 957-965.
    • (2008) Gut , vol.57 , pp. 957-965
    • Serviddio, G.1    Bellanti, F.2    Tamborra, R.3    Rollo, T.4    Capitanio, N.5    Romano, A.D.6
  • 30
    • 0033538473 scopus 로고    scopus 로고
    • Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
    • Wu Z, Puigserver P, Andersson U, Zhang C, Adelmant G, Mootha V et al. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 1999; 98: 115-124.
    • (1999) Cell , vol.98 , pp. 115-124
    • Wu, Z.1    Puigserver, P.2    Andersson, U.3    Zhang, C.4    Adelmant, G.5    Mootha, V.6
  • 31
    • 33744963543 scopus 로고    scopus 로고
    • Partnership of PGC-1a and HNF4a in the regulation of lipoprotein metabolism
    • Rhee J, Ge H, Yang W, Fan M, Handschin C, Cooper M et al. Partnership of PGC-1a and HNF4a in the regulation of lipoprotein metabolism. J Biol Chem 2006; 281: 14683-14690.
    • (2006) J Biol Chem , vol.281 , pp. 14683-14690
    • Rhee, J.1    Ge, H.2    Yang, W.3    Fan, M.4    Handschin, C.5    Cooper, M.6
  • 33
    • 0033515429 scopus 로고    scopus 로고
    • Deconstructing type 2 diabetes
    • Simeon IT. Deconstructing type 2 diabetes. Cell 1999; 97: 9-12.
    • (1999) Cell , vol.97 , pp. 9-12
    • Simeon, I.T.1
  • 34
  • 35
    • 3543009434 scopus 로고    scopus 로고
    • The high-fat diet-fed mouse: A model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetes
    • Winzell MS, Ahren B. The high-fat diet-fed mouse: a model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetes. Diabetes 2004; 53(Suppl 3): S215-S219.
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 3
    • Winzell, M.S.1    Ahren, B.2
  • 38
    • 66149102890 scopus 로고    scopus 로고
    • The role of FOXO in the regulation of metabolism
    • Gross DN, Wan M, Birnbaum MJ. The role of FOXO in the regulation of metabolism. Curr Diab Rep 2009; 9: 208-214.
    • (2009) Curr Diab Rep , vol.9 , pp. 208-214
    • Gross, D.N.1    Wan, M.2    Birnbaum, M.J.3
  • 39
    • 78149272381 scopus 로고    scopus 로고
    • FoxOs function synergistically to promote glucose production
    • Haeusler RA, Kaestner KH, Accili D. FoxOs function synergistically to promote glucose production. J Biol Chem 2010; 285: 35245-35248.
    • (2010) J Biol Chem , vol.285 , pp. 35245-35248
    • Haeusler, R.A.1    Kaestner, K.H.2    Accili, D.3
  • 40
  • 42
    • 0035855858 scopus 로고    scopus 로고
    • Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
    • Yoon JC, Puigserver P, Chen G, Donovan J, Wu Z, Rhee J et al. Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature 2001; 413: 131-138.
    • (2001) Nature , vol.413 , pp. 131-138
    • Yoon, J.C.1    Puigserver, P.2    Chen, G.3    Donovan, J.4    Wu, Z.5    Rhee, J.6
  • 43
    • 30944450418 scopus 로고    scopus 로고
    • Role of peroxisome proliferator-activated receptor-gamma coactivator-1alpha in the transcriptional regulation of the human uncoupling protein 2 gene in INS-1E cells
    • Oberkofler H, Klein K, Felder TK, Krempler F, Patsch W. Role of peroxisome proliferator-activated receptor-gamma coactivator-1alpha in the transcriptional regulation of the human uncoupling protein 2 gene in INS-1E cells. Endocrinology 2006; 147: 966-976.
    • (2006) Endocrinology , vol.147 , pp. 966-976
    • Oberkofler, H.1    Klein, K.2    Felder, T.K.3    Krempler, F.4    Patsch, W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.