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Volumn 53, Issue 7, 2013, Pages 1818-1824

Computational repositioning and experimental validation of approved drugs for HIF-prolyl hydroxylase inhibition

Author keywords

[No Author keywords available]

Indexed keywords

MACHINERY; SURVEYS;

EID: 84880545825     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci400254a     Document Type: Article
Times cited : (14)

References (37)
  • 1
    • 70449627018 scopus 로고    scopus 로고
    • The role and regulation of hypoxia-inducible factor-1α expression in brain development and neonatal hypoxic-ischemic brain injury
    • Fan, X.; Heijnen, C. J.; van-der-Kooij, M. A.; Groenendaal, F.; van-Bel, F. The role and regulation of hypoxia-inducible factor-1α expression in brain development and neonatal hypoxic-ischemic brain injury Brain Res. Rev. 2009, 62, 99-108
    • (2009) Brain Res. Rev. , vol.62 , pp. 99-108
    • Fan, X.1    Heijnen, C.J.2    Van-Der-Kooij, M.A.3    Groenendaal, F.4    Van-Bel, F.5
  • 2
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza, G. L. Targeting HIF-1 for cancer therapy Nat. Rev. Cancer 2003, 3, 721-732
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 3
    • 31444444162 scopus 로고    scopus 로고
    • Integration of oxygen signaling at the consensus HRE
    • Wenger, R. H.; Stiehl, D. P.; Camenisch, G. Integration of oxygen signaling at the consensus HRE Sci. Signaling 2005, 306, re12
    • (2005) Sci. Signaling , vol.306 , pp. 12
    • Wenger, R.H.1    Stiehl, D.P.2    Camenisch, G.3
  • 4
    • 33744954065 scopus 로고    scopus 로고
    • Concordant regulation of gene expression by hypoxia and 2-oxoglutarate dependent dioxygenase inhibition; The role of HIF-1α, HIF-2α and other pathways
    • Elvidge, G. P.; Glenny, L.; Appelhoff, R. J.; Ratcliffe, P. J.; Ragoussis, J.; Gleadle, J. M. Concordant regulation of gene expression by hypoxia and 2-oxoglutarate dependent dioxygenase inhibition; the role of HIF-1α, HIF-2α and other pathways J. Biol. Chem. 2006, 281, 15215-15226
    • (2006) J. Biol. Chem. , vol.281 , pp. 15215-15226
    • Elvidge, G.P.1    Glenny, L.2    Appelhoff, R.J.3    Ratcliffe, P.J.4    Ragoussis, J.5    Gleadle, J.M.6
  • 5
    • 79251535600 scopus 로고    scopus 로고
    • Hypoxia. 1. Intracellular sensors for oxygen and oxidative stress: Novel therapeutic targets
    • Miyata, T.; Takizawa, S.; van, Y.; persele-de-Strihou, C. Hypoxia. 1. Intracellular sensors for oxygen and oxidative stress: novel therapeutic targets Am. J. Physiol. Cell Physiol. 2011, 300, C226-C231
    • (2011) Am. J. Physiol. Cell Physiol. , vol.300
    • Miyata, T.1    Takizawa, S.2    Van, Y.3    Persele-De-Strihou, C.4
  • 6
    • 79960700105 scopus 로고    scopus 로고
    • The hypoxia-inflammation link and potential drug targets
    • Koeppen, M.; Eckle, T.; Eltzschig, H. K. The hypoxia-inflammation link and potential drug targets Curr. Opin. Anaesthesiol. 2011, 24, 363-369
    • (2011) Curr. Opin. Anaesthesiol. , vol.24 , pp. 363-369
    • Koeppen, M.1    Eckle, T.2    Eltzschig, H.K.3
  • 8
    • 0028221633 scopus 로고
    • Neuroprotection from ischemic brain injury by hypoxic preconditioning in the neonatal rat
    • Gidday, J. M.; Fitzgibbons, J. C.; Shah, A. R.; Park, T. S. Neuroprotection from ischemic brain injury by hypoxic preconditioning in the neonatal rat Neurosci. Lett. 1994, 168, 221-224
    • (1994) Neurosci. Lett. , vol.168 , pp. 221-224
    • Gidday, J.M.1    Fitzgibbons, J.C.2    Shah, A.R.3    Park, T.S.4
  • 9
    • 0035854092 scopus 로고    scopus 로고
    • Cerebral protection by hypoxic preconditioning in a murine model of focal ischemia-reperfusion
    • Miller, B. A.; Perez, R. S.; Shah, A. R.; Gonzales, E. R.; Park, T. S.; Gidday, J. M. Cerebral protection by hypoxic preconditioning in a murine model of focal ischemia-reperfusion NeuroReport 2001, 12, 1663-1669
    • (2001) NeuroReport , vol.12 , pp. 1663-1669
    • Miller, B.A.1    Perez, R.S.2    Shah, A.R.3    Gonzales, E.R.4    Park, T.S.5    Gidday, J.M.6
  • 11
    • 67650481882 scopus 로고    scopus 로고
    • Selective inhibition of hypoxia-inducible factor (HIF) prolyl-hydroxylase 1 mediates neuroprotection against normoxic oxidative death via HIF- and CREB-independent pathways
    • Siddiq, A.; Aminova, L. R.; Troy, C. M.; Suh, K.; Messer, Z.; Semenza, G. L.; Ratan, R. R. Selective inhibition of hypoxia-inducible factor (HIF) prolyl-hydroxylase 1 mediates neuroprotection against normoxic oxidative death via HIF- and CREB-independent pathways J. Neurosci. 2009, 29, 8828-8838
    • (2009) J. Neurosci. , vol.29 , pp. 8828-8838
    • Siddiq, A.1    Aminova, L.R.2    Troy, C.M.3    Suh, K.4    Messer, Z.5    Semenza, G.L.6    Ratan, R.R.7
  • 12
    • 84858705244 scopus 로고    scopus 로고
    • Identification of novel potential HIF-prolyl hydroxylase inhibitors by in silico screening
    • Teli, M. K.; Rajanikant, G. K. Identification of novel potential HIF-prolyl hydroxylase inhibitors by in silico screening Mol. Divers. 2012, 16, 193-202
    • (2012) Mol. Divers. , vol.16 , pp. 193-202
    • Teli, M.K.1    Rajanikant, G.K.2
  • 15
    • 84877994846 scopus 로고    scopus 로고
    • A combination of 3D-QSAR modeling and molecular docking approach for the discovery of potential HIF prolyl hydroxylase inhibitors
    • Teli, M. K.; Krishnamurthy, R. G. A combination of 3D-QSAR modeling and molecular docking approach for the discovery of potential HIF prolyl hydroxylase inhibitors Med. Chem. 2013, 9, 360-370
    • (2013) Med. Chem. , vol.9 , pp. 360-370
    • Teli, M.K.1    Krishnamurthy, R.G.2
  • 16
    • 84880561301 scopus 로고    scopus 로고
    • Pharmacophore generation and atom-based 3D-QSAR of N-iso-propyl pyrrole-based derivatives as HMG-CoA reductase inhibitors
    • Teli, M. K.; Krishnamurthy, R. G. Pharmacophore generation and atom-based 3D-QSAR of N-iso-propyl pyrrole-based derivatives as HMG-CoA reductase inhibitors Org. Med. Chem. Lett. 2012, 2, 25
    • (2012) Org. Med. Chem. Lett. , vol.2 , pp. 25
    • Teli, M.K.1    Krishnamurthy, R.G.2
  • 17
    • 84864062864 scopus 로고    scopus 로고
    • Pharmacophore generation and atom-based 3D-QSAR of novel quinoline-3-carbonitrile derivatives as Tpl2 kinase inhibitors
    • Teli, M. K.; Rajanikant, G. K. Pharmacophore generation and atom-based 3D-QSAR of novel quinoline-3-carbonitrile derivatives as Tpl2 kinase inhibitors J. Enzyme Inhib. Med. Chem. 2012, 27, 558-570
    • (2012) J. Enzyme Inhib. Med. Chem. , vol.27 , pp. 558-570
    • Teli, M.K.1    Rajanikant, G.K.2
  • 18
    • 84880553169 scopus 로고    scopus 로고
    • Glide, version 5.5, Schrödinger, LLC, New York
    • Glide, version 5.5, Schrödinger, LLC, New York, 2009.
    • (2009)
  • 19
    • 84880567503 scopus 로고    scopus 로고
    • Schrödinger Suite 2009 Protein Preparation Wizard; Epik version 2.0, Schrödinger, LLC, New York
    • Schrödinger Suite 2009 Protein Preparation Wizard; Epik version 2.0, Schrödinger, LLC, New York, 2009.
    • (2009)
  • 20
    • 84880558833 scopus 로고    scopus 로고
    • Impact, version 5.5, Schrödinger, LLC, New York
    • Impact, version 5.5, Schrödinger, LLC, New York, 2009
    • (2009)
  • 21
    • 84880545601 scopus 로고    scopus 로고
    • Prime, version 2.1, Schrödinger, LLC, New York
    • Prime, version 2.1, Schrödinger, LLC, New York, 2009.
    • (2009)
  • 22
    • 80052559963 scopus 로고    scopus 로고
    • Rapid screening method for quinolone residues in livestock and fishery products using immobilised metal chelate affinity chromatographic clean-up and liquid chromatography-fluorescence detection
    • Takeda, N.; Gotoh, M.; Matsuoka, T. Rapid screening method for quinolone residues in livestock and fishery products using immobilised metal chelate affinity chromatographic clean-up and liquid chromatography-fluorescence detection Food Addit. Contam., Part A. 2011, 28, 1168-1174
    • (2011) Food Addit. Contam., Part A. , vol.28 , pp. 1168-1174
    • Takeda, N.1    Gotoh, M.2    Matsuoka, T.3
  • 23
    • 0017837659 scopus 로고
    • The effect of nalidixic acid group compounds on reduction of cytochrome c from horse heart and Candida krusei
    • Yamabe, S. The effect of nalidixic acid group compounds on reduction of cytochrome c from horse heart and Candida krusei J. Gen. Microbiol. 1978, 105, 227-232
    • (1978) J. Gen. Microbiol. , vol.105 , pp. 227-232
    • Yamabe, S.1
  • 24
    • 84861923067 scopus 로고    scopus 로고
    • Screening chelating inhibitors of HIF-prolyl hydroxylase domain 2 (PHD2) and factor inhibiting HIF (FIH)
    • Flagg, S. C.; Martin, C. B.; Taabazuing, C. Y.; Holmes, B. E.; Knapp, M. J. Screening chelating inhibitors of HIF-prolyl hydroxylase domain 2 (PHD2) and factor inhibiting HIF (FIH) J. Inorg. Biochem. 2012, 113, 25-30
    • (2012) J. Inorg. Biochem. , vol.113 , pp. 25-30
    • Flagg, S.C.1    Martin, C.B.2    Taabazuing, C.Y.3    Holmes, B.E.4    Knapp, M.J.5
  • 25
    • 79959433994 scopus 로고    scopus 로고
    • Protective effects of deferoxamine mesylate preconditioning on pancreatic tissue in orthotopic liver auto transplantation in rats
    • Li, Y.; Zhang, P. J.; Jin, C.; Zhou, B.; Liu, X. Y.; Tao, L. D.; Feng, M. Protective effects of deferoxamine mesylate preconditioning on pancreatic tissue in orthotopic liver auto transplantation in rats Transplant Proc. 2011, 43, 1450-1455
    • (2011) Transplant Proc. , vol.43 , pp. 1450-1455
    • Li, Y.1    Zhang, P.J.2    Jin, C.3    Zhou, B.4    Liu, X.Y.5    Tao, L.D.6    Feng, M.7
  • 26
    • 33646836104 scopus 로고    scopus 로고
    • Hyperhomocysteinemia increases damage on brain slices exposed to in vitro model of oxygen and glucose deprivation: Prevention by folic acid
    • Tagliari, B.; Zamin, L. L.; Salbego, C. G.; Netto, C. A.; Wyse, A. T. Hyperhomocysteinemia increases damage on brain slices exposed to in vitro model of oxygen and glucose deprivation: Prevention by folic acid Int. J. Dev. Neurosci. 2006, 24, 285-291
    • (2006) Int. J. Dev. Neurosci. , vol.24 , pp. 285-291
    • Tagliari, B.1    Zamin, L.L.2    Salbego, C.G.3    Netto, C.A.4    Wyse, A.T.5
  • 28
    • 70450235125 scopus 로고    scopus 로고
    • The effects of METhotrexate therapy on the physical capacity of patients with ISchemic heart failure: A randomized double-blind, placebo-controlled trial (METIS trial)
    • Moreira, D. M.; Vieira, J. L.; Gottschall, C. A. The effects of METhotrexate therapy on the physical capacity of patients with ISchemic heart failure: A randomized double-blind, placebo-controlled trial (METIS trial) J. Card. Fail. 2009, 15, 828-834
    • (2009) J. Card. Fail. , vol.15 , pp. 828-834
    • Moreira, D.M.1    Vieira, J.L.2    Gottschall, C.A.3
  • 29
    • 22944470530 scopus 로고    scopus 로고
    • Low-dose methotrexate: A mainstay in the treatment of rheumatoid arthritis
    • Cronstein, B N. Low-dose methotrexate: A mainstay in the treatment of rheumatoid arthritis Pharmacol. Rev. 2005, 57, 163-172
    • (2005) Pharmacol. Rev. , vol.57 , pp. 163-172
    • Cronstein, B.N.1
  • 30
    • 78549277149 scopus 로고    scopus 로고
    • Intrathecal methotrexate treatment in multiple sclerosis
    • Sadiq, S. A.; Simon, E. V.; Puccio, L. M. Intrathecal methotrexate treatment in multiple sclerosis J. Neurol. 2010, 257, 1806-1811
    • (2010) J. Neurol. , vol.257 , pp. 1806-1811
    • Sadiq, S.A.1    Simon, E.V.2    Puccio, L.M.3
  • 31
    • 77957221783 scopus 로고    scopus 로고
    • Profound cardioprotection with chloramphenicol succinate in the swine model of myocardial ischemia-reperfusion injury
    • Sala-Mercado, J. A.; Wider, J.; Undyala, V. V.; Jahania, S.; Yoo, W.; Mentzer, R. M.; Gottlieb, R. A.; Przyklenk, K. Profound cardioprotection with chloramphenicol succinate in the swine model of myocardial ischemia-reperfusion injury Circulation 2010, 122, S179-184
    • (2010) Circulation , vol.122 , pp. 179-184
    • Sala-Mercado, J.A.1    Wider, J.2    Undyala, V.V.3    Jahania, S.4    Yoo, W.5    Mentzer, R.M.6    Gottlieb, R.A.7    Przyklenk, K.8


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