-
1
-
-
70449627018
-
The role and regulation of hypoxia-inducible factor-1α expression in brain development and neonatal hypoxic-ischemic brain injury
-
Fan, X.; Heijnen, C. J.; van-der-Kooij, M. A.; Groenendaal, F.; van-Bel, F. The role and regulation of hypoxia-inducible factor-1α expression in brain development and neonatal hypoxic-ischemic brain injury Brain Res. Rev. 2009, 62, 99-108
-
(2009)
Brain Res. Rev.
, vol.62
, pp. 99-108
-
-
Fan, X.1
Heijnen, C.J.2
Van-Der-Kooij, M.A.3
Groenendaal, F.4
Van-Bel, F.5
-
2
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza, G. L. Targeting HIF-1 for cancer therapy Nat. Rev. Cancer 2003, 3, 721-732
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
3
-
-
31444444162
-
Integration of oxygen signaling at the consensus HRE
-
Wenger, R. H.; Stiehl, D. P.; Camenisch, G. Integration of oxygen signaling at the consensus HRE Sci. Signaling 2005, 306, re12
-
(2005)
Sci. Signaling
, vol.306
, pp. 12
-
-
Wenger, R.H.1
Stiehl, D.P.2
Camenisch, G.3
-
4
-
-
33744954065
-
Concordant regulation of gene expression by hypoxia and 2-oxoglutarate dependent dioxygenase inhibition; The role of HIF-1α, HIF-2α and other pathways
-
Elvidge, G. P.; Glenny, L.; Appelhoff, R. J.; Ratcliffe, P. J.; Ragoussis, J.; Gleadle, J. M. Concordant regulation of gene expression by hypoxia and 2-oxoglutarate dependent dioxygenase inhibition; the role of HIF-1α, HIF-2α and other pathways J. Biol. Chem. 2006, 281, 15215-15226
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 15215-15226
-
-
Elvidge, G.P.1
Glenny, L.2
Appelhoff, R.J.3
Ratcliffe, P.J.4
Ragoussis, J.5
Gleadle, J.M.6
-
5
-
-
79251535600
-
Hypoxia. 1. Intracellular sensors for oxygen and oxidative stress: Novel therapeutic targets
-
Miyata, T.; Takizawa, S.; van, Y.; persele-de-Strihou, C. Hypoxia. 1. Intracellular sensors for oxygen and oxidative stress: novel therapeutic targets Am. J. Physiol. Cell Physiol. 2011, 300, C226-C231
-
(2011)
Am. J. Physiol. Cell Physiol.
, vol.300
-
-
Miyata, T.1
Takizawa, S.2
Van, Y.3
Persele-De-Strihou, C.4
-
6
-
-
79960700105
-
The hypoxia-inflammation link and potential drug targets
-
Koeppen, M.; Eckle, T.; Eltzschig, H. K. The hypoxia-inflammation link and potential drug targets Curr. Opin. Anaesthesiol. 2011, 24, 363-369
-
(2011)
Curr. Opin. Anaesthesiol.
, vol.24
, pp. 363-369
-
-
Koeppen, M.1
Eckle, T.2
Eltzschig, H.K.3
-
7
-
-
84860865685
-
HIF-prolyl hydroxylases and cardiovascular diseases
-
Sen-Banerjee, S.; Thirunavukkarasu, M.; Tipu, R. M.; Sanchez, J. A.; Maulik, N.; Maulik, G. HIF-prolyl hydroxylases and cardiovascular diseases Toxicol. Mech. Methods 2012, 22, 347-358
-
(2012)
Toxicol. Mech. Methods
, vol.22
, pp. 347-358
-
-
Sen-Banerjee, S.1
Thirunavukkarasu, M.2
Tipu, R.M.3
Sanchez, J.A.4
Maulik, N.5
Maulik, G.6
-
8
-
-
0028221633
-
Neuroprotection from ischemic brain injury by hypoxic preconditioning in the neonatal rat
-
Gidday, J. M.; Fitzgibbons, J. C.; Shah, A. R.; Park, T. S. Neuroprotection from ischemic brain injury by hypoxic preconditioning in the neonatal rat Neurosci. Lett. 1994, 168, 221-224
-
(1994)
Neurosci. Lett.
, vol.168
, pp. 221-224
-
-
Gidday, J.M.1
Fitzgibbons, J.C.2
Shah, A.R.3
Park, T.S.4
-
9
-
-
0035854092
-
Cerebral protection by hypoxic preconditioning in a murine model of focal ischemia-reperfusion
-
Miller, B. A.; Perez, R. S.; Shah, A. R.; Gonzales, E. R.; Park, T. S.; Gidday, J. M. Cerebral protection by hypoxic preconditioning in a murine model of focal ischemia-reperfusion NeuroReport 2001, 12, 1663-1669
-
(2001)
NeuroReport
, vol.12
, pp. 1663-1669
-
-
Miller, B.A.1
Perez, R.S.2
Shah, A.R.3
Gonzales, E.R.4
Park, T.S.5
Gidday, J.M.6
-
10
-
-
23244459292
-
Hypoxia preconditioning in the brain
-
Ran, R.; Xu, H.; Lu, A.; Bernaudin, M.; Sharp, F. R. Hypoxia preconditioning in the brain Dev. Neurosci. 2005, 27, 87-92
-
(2005)
Dev. Neurosci.
, vol.27
, pp. 87-92
-
-
Ran, R.1
Xu, H.2
Lu, A.3
Bernaudin, M.4
Sharp, F.R.5
-
11
-
-
67650481882
-
Selective inhibition of hypoxia-inducible factor (HIF) prolyl-hydroxylase 1 mediates neuroprotection against normoxic oxidative death via HIF- and CREB-independent pathways
-
Siddiq, A.; Aminova, L. R.; Troy, C. M.; Suh, K.; Messer, Z.; Semenza, G. L.; Ratan, R. R. Selective inhibition of hypoxia-inducible factor (HIF) prolyl-hydroxylase 1 mediates neuroprotection against normoxic oxidative death via HIF- and CREB-independent pathways J. Neurosci. 2009, 29, 8828-8838
-
(2009)
J. Neurosci.
, vol.29
, pp. 8828-8838
-
-
Siddiq, A.1
Aminova, L.R.2
Troy, C.M.3
Suh, K.4
Messer, Z.5
Semenza, G.L.6
Ratan, R.R.7
-
12
-
-
84858705244
-
Identification of novel potential HIF-prolyl hydroxylase inhibitors by in silico screening
-
Teli, M. K.; Rajanikant, G. K. Identification of novel potential HIF-prolyl hydroxylase inhibitors by in silico screening Mol. Divers. 2012, 16, 193-202
-
(2012)
Mol. Divers.
, vol.16
, pp. 193-202
-
-
Teli, M.K.1
Rajanikant, G.K.2
-
13
-
-
78649876180
-
Inhibition of prolyl hydroxylases increases erythropoietin production in ESRD
-
Bernhardt, W. M.; Wiesener, M. S.; Scigalla, P.; Chou, J.; Schmieder, R. E.; Günzler, V.; Eckardt, K. U. Inhibition of prolyl hydroxylases increases erythropoietin production in ESRD J. Am. Soc. Nephrol. 2010, 21, 2151-2156
-
(2010)
J. Am. Soc. Nephrol.
, vol.21
, pp. 2151-2156
-
-
Bernhardt, W.M.1
Wiesener, M.S.2
Scigalla, P.3
Chou, J.4
Schmieder, R.E.5
Günzler, V.6
Eckardt, K.U.7
-
14
-
-
84874907312
-
Drug repurposing a reality: From computers to the clinic
-
Issa, N. T.; Kruger, J.; Byers, S. W.; Dakshanamurthy, S. Drug repurposing a reality: From computers to the clinic Expert Rev. Clin. Pharmacol. 2013, 6, 95-97
-
(2013)
Expert Rev. Clin. Pharmacol.
, vol.6
, pp. 95-97
-
-
Issa, N.T.1
Kruger, J.2
Byers, S.W.3
Dakshanamurthy, S.4
-
15
-
-
84877994846
-
A combination of 3D-QSAR modeling and molecular docking approach for the discovery of potential HIF prolyl hydroxylase inhibitors
-
Teli, M. K.; Krishnamurthy, R. G. A combination of 3D-QSAR modeling and molecular docking approach for the discovery of potential HIF prolyl hydroxylase inhibitors Med. Chem. 2013, 9, 360-370
-
(2013)
Med. Chem.
, vol.9
, pp. 360-370
-
-
Teli, M.K.1
Krishnamurthy, R.G.2
-
16
-
-
84880561301
-
Pharmacophore generation and atom-based 3D-QSAR of N-iso-propyl pyrrole-based derivatives as HMG-CoA reductase inhibitors
-
Teli, M. K.; Krishnamurthy, R. G. Pharmacophore generation and atom-based 3D-QSAR of N-iso-propyl pyrrole-based derivatives as HMG-CoA reductase inhibitors Org. Med. Chem. Lett. 2012, 2, 25
-
(2012)
Org. Med. Chem. Lett.
, vol.2
, pp. 25
-
-
Teli, M.K.1
Krishnamurthy, R.G.2
-
17
-
-
84864062864
-
Pharmacophore generation and atom-based 3D-QSAR of novel quinoline-3-carbonitrile derivatives as Tpl2 kinase inhibitors
-
Teli, M. K.; Rajanikant, G. K. Pharmacophore generation and atom-based 3D-QSAR of novel quinoline-3-carbonitrile derivatives as Tpl2 kinase inhibitors J. Enzyme Inhib. Med. Chem. 2012, 27, 558-570
-
(2012)
J. Enzyme Inhib. Med. Chem.
, vol.27
, pp. 558-570
-
-
Teli, M.K.1
Rajanikant, G.K.2
-
18
-
-
84880553169
-
-
Glide, version 5.5, Schrödinger, LLC, New York
-
Glide, version 5.5, Schrödinger, LLC, New York, 2009.
-
(2009)
-
-
-
19
-
-
84880567503
-
-
Schrödinger Suite 2009 Protein Preparation Wizard; Epik version 2.0, Schrödinger, LLC, New York
-
Schrödinger Suite 2009 Protein Preparation Wizard; Epik version 2.0, Schrödinger, LLC, New York, 2009.
-
(2009)
-
-
-
20
-
-
84880558833
-
-
Impact, version 5.5, Schrödinger, LLC, New York
-
Impact, version 5.5, Schrödinger, LLC, New York, 2009
-
(2009)
-
-
-
21
-
-
84880545601
-
-
Prime, version 2.1, Schrödinger, LLC, New York
-
Prime, version 2.1, Schrödinger, LLC, New York, 2009.
-
(2009)
-
-
-
22
-
-
80052559963
-
Rapid screening method for quinolone residues in livestock and fishery products using immobilised metal chelate affinity chromatographic clean-up and liquid chromatography-fluorescence detection
-
Takeda, N.; Gotoh, M.; Matsuoka, T. Rapid screening method for quinolone residues in livestock and fishery products using immobilised metal chelate affinity chromatographic clean-up and liquid chromatography-fluorescence detection Food Addit. Contam., Part A. 2011, 28, 1168-1174
-
(2011)
Food Addit. Contam., Part A.
, vol.28
, pp. 1168-1174
-
-
Takeda, N.1
Gotoh, M.2
Matsuoka, T.3
-
23
-
-
0017837659
-
The effect of nalidixic acid group compounds on reduction of cytochrome c from horse heart and Candida krusei
-
Yamabe, S. The effect of nalidixic acid group compounds on reduction of cytochrome c from horse heart and Candida krusei J. Gen. Microbiol. 1978, 105, 227-232
-
(1978)
J. Gen. Microbiol.
, vol.105
, pp. 227-232
-
-
Yamabe, S.1
-
24
-
-
84861923067
-
Screening chelating inhibitors of HIF-prolyl hydroxylase domain 2 (PHD2) and factor inhibiting HIF (FIH)
-
Flagg, S. C.; Martin, C. B.; Taabazuing, C. Y.; Holmes, B. E.; Knapp, M. J. Screening chelating inhibitors of HIF-prolyl hydroxylase domain 2 (PHD2) and factor inhibiting HIF (FIH) J. Inorg. Biochem. 2012, 113, 25-30
-
(2012)
J. Inorg. Biochem.
, vol.113
, pp. 25-30
-
-
Flagg, S.C.1
Martin, C.B.2
Taabazuing, C.Y.3
Holmes, B.E.4
Knapp, M.J.5
-
25
-
-
79959433994
-
Protective effects of deferoxamine mesylate preconditioning on pancreatic tissue in orthotopic liver auto transplantation in rats
-
Li, Y.; Zhang, P. J.; Jin, C.; Zhou, B.; Liu, X. Y.; Tao, L. D.; Feng, M. Protective effects of deferoxamine mesylate preconditioning on pancreatic tissue in orthotopic liver auto transplantation in rats Transplant Proc. 2011, 43, 1450-1455
-
(2011)
Transplant Proc.
, vol.43
, pp. 1450-1455
-
-
Li, Y.1
Zhang, P.J.2
Jin, C.3
Zhou, B.4
Liu, X.Y.5
Tao, L.D.6
Feng, M.7
-
26
-
-
33646836104
-
Hyperhomocysteinemia increases damage on brain slices exposed to in vitro model of oxygen and glucose deprivation: Prevention by folic acid
-
Tagliari, B.; Zamin, L. L.; Salbego, C. G.; Netto, C. A.; Wyse, A. T. Hyperhomocysteinemia increases damage on brain slices exposed to in vitro model of oxygen and glucose deprivation: Prevention by folic acid Int. J. Dev. Neurosci. 2006, 24, 285-291
-
(2006)
Int. J. Dev. Neurosci.
, vol.24
, pp. 285-291
-
-
Tagliari, B.1
Zamin, L.L.2
Salbego, C.G.3
Netto, C.A.4
Wyse, A.T.5
-
27
-
-
84864327658
-
Folic acid prevents behavioral impairment and Na(+), K(+) -ATPase inhibition caused by neonatal hypoxia-ischemia
-
Carletti, J. V.; Deniz, B. F.; Miguel, P. M.; Rojas, J. J.; Kolling, J.; Scherer, E. B.; de-Souza-Wyse, A. T.; Netto, C. A.; Pereira, L. O. Folic acid prevents behavioral impairment and Na(+), K(+) -ATPase inhibition caused by neonatal hypoxia-ischemia Neurochem. Res. 2012, 37, 1624-1630
-
(2012)
Neurochem. Res.
, vol.37
, pp. 1624-1630
-
-
Carletti, J.V.1
Deniz, B.F.2
Miguel, P.M.3
Rojas, J.J.4
Kolling, J.5
Scherer, E.B.6
De-Souza-Wyse, A.T.7
Netto, C.A.8
Pereira, L.O.9
-
28
-
-
70450235125
-
The effects of METhotrexate therapy on the physical capacity of patients with ISchemic heart failure: A randomized double-blind, placebo-controlled trial (METIS trial)
-
Moreira, D. M.; Vieira, J. L.; Gottschall, C. A. The effects of METhotrexate therapy on the physical capacity of patients with ISchemic heart failure: A randomized double-blind, placebo-controlled trial (METIS trial) J. Card. Fail. 2009, 15, 828-834
-
(2009)
J. Card. Fail.
, vol.15
, pp. 828-834
-
-
Moreira, D.M.1
Vieira, J.L.2
Gottschall, C.A.3
-
29
-
-
22944470530
-
Low-dose methotrexate: A mainstay in the treatment of rheumatoid arthritis
-
Cronstein, B N. Low-dose methotrexate: A mainstay in the treatment of rheumatoid arthritis Pharmacol. Rev. 2005, 57, 163-172
-
(2005)
Pharmacol. Rev.
, vol.57
, pp. 163-172
-
-
Cronstein, B.N.1
-
30
-
-
78549277149
-
Intrathecal methotrexate treatment in multiple sclerosis
-
Sadiq, S. A.; Simon, E. V.; Puccio, L. M. Intrathecal methotrexate treatment in multiple sclerosis J. Neurol. 2010, 257, 1806-1811
-
(2010)
J. Neurol.
, vol.257
, pp. 1806-1811
-
-
Sadiq, S.A.1
Simon, E.V.2
Puccio, L.M.3
-
31
-
-
77957221783
-
Profound cardioprotection with chloramphenicol succinate in the swine model of myocardial ischemia-reperfusion injury
-
Sala-Mercado, J. A.; Wider, J.; Undyala, V. V.; Jahania, S.; Yoo, W.; Mentzer, R. M.; Gottlieb, R. A.; Przyklenk, K. Profound cardioprotection with chloramphenicol succinate in the swine model of myocardial ischemia-reperfusion injury Circulation 2010, 122, S179-184
-
(2010)
Circulation
, vol.122
, pp. 179-184
-
-
Sala-Mercado, J.A.1
Wider, J.2
Undyala, V.V.3
Jahania, S.4
Yoo, W.5
Mentzer, R.M.6
Gottlieb, R.A.7
Przyklenk, K.8
-
32
-
-
0842299582
-
Reduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors
-
Granville, D. J.; Tashakkor, B.; Takeuchi, C.; Gustafsson, A. B.; Huang, C.; Sayen, M. R.; Wentworth, P., Jr.; Yeager, M.; Gottlieb, R. A. Reduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors Proc. Natl. Acad. Sci. U.S.A. 2004, 5, 1321-1326
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.5
, pp. 1321-1326
-
-
Granville, D.J.1
Tashakkor, B.2
Takeuchi, C.3
Gustafsson, A.B.4
Huang, C.5
Sayen, M.R.6
Wentworth Jr., P.7
Yeager, M.8
Gottlieb, R.A.9
-
34
-
-
78650494478
-
In vitro effect of aspartame in angiogenesis induction
-
Alleva, R.; Borghi, B.; Santarelli, L.; Strafella, E.; Carbonari, D.; Bracci, M.; Tomasetti, M. In vitro effect of aspartame in angiogenesis induction Toxicol. In Vitro 2011, 25, 286-293
-
(2011)
Toxicol. in Vitro
, vol.25
, pp. 286-293
-
-
Alleva, R.1
Borghi, B.2
Santarelli, L.3
Strafella, E.4
Carbonari, D.5
Bracci, M.6
Tomasetti, M.7
-
35
-
-
0035338740
-
Aspartame effect in sickle cell anemia
-
Manion, C. V.; Howard, J.; Ogle, B.; Parkhurst, J.; Edmundson, A. Aspartame effect in sickle cell anemia Clin. Pharmacol. Ther. 2001, 69, 346-355
-
(2001)
Clin. Pharmacol. Ther.
, vol.69
, pp. 346-355
-
-
Manion, C.V.1
Howard, J.2
Ogle, B.3
Parkhurst, J.4
Edmundson, A.5
-
36
-
-
84877897621
-
Acute mountain sickness prophylaxis: A high-altitude perspective
-
DeLellis, S. M.; Anderson, S. E.; Lynch, J. H.; Kratz, K. Acute mountain sickness prophylaxis: A high-altitude perspective Curr. Sports Med. Rep. 2013, 12, 110-114
-
(2013)
Curr. Sports Med. Rep.
, vol.12
, pp. 110-114
-
-
Delellis, S.M.1
Anderson, S.E.2
Lynch, J.H.3
Kratz, K.4
-
37
-
-
59149107403
-
Normoxic induction of cerebral HIF-1alpha by acetazolamide in rats: Role of acidosis
-
Xu, J.; Peng, Z.; Li, R.; Dou, T.; Xu, W.; Gu, G.; Liu, Y.; Kang, Z.; Tao, H.; Zhang, J. H.; Ostrowski, R. P.; Lu, J.; Sun, X. Normoxic induction of cerebral HIF-1alpha by acetazolamide in rats: Role of acidosis Neurosci. Lett. 2009, 451, 274-278
-
(2009)
Neurosci. Lett.
, vol.451
, pp. 274-278
-
-
Xu, J.1
Peng, Z.2
Li, R.3
Dou, T.4
Xu, W.5
Gu, G.6
Liu, Y.7
Kang, Z.8
Tao, H.9
Zhang, J.H.10
Ostrowski, R.P.11
Lu, J.12
Sun, X.13
|