Reduction in the urinary aflatoxin M1 biomarker as an early indicator of the efficacy of dietary interventions to reduce exposure to aflatoxins

Biomarkers

Volumn 18, Issue 5, 2013, Pages 391-398

  Mitchell, Nicole J ^a   Kumi, Justice ^b   Johnson, Natalie M ^a,c   Dotse, Eunice ^b   Marroquin Cardona, Alicia ^a,d   Wang, Jia Sheng ^e   Jolly, Pauline E ^f   Ankrah, Nii Ayi ^b   Phillips, Timothy D ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b University of Ghana   (Ghana)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^d UNIVERSIDAD AUTÓNOMA DE NUEVO LEÓN   (Mexico)

^e UNIVERSITY OF GEORGIA   (United States)

^f UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Aflatoxin; Enterosorption therapy; Ghana; Liver cancer

Indexed keywords

AFLATOXIN; AFLATOXIN M1; CALCIUM CARBONATE; CALCIUM MONTMORILLONITE CLAY; MONTMORILLONITE; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; DIET; FEMALE; GHANA; HUMAN; MAJOR CLINICAL STUDY; MALE; PARTICLE SIZE; UNIFORM PARTICLE SIZE; URINALYSIS;

ADSORPTION; ADULT; AFLATOXIN B1; AFLATOXIN M1; AGED; ANTIDOTES; BENTONITE; BIOLOGICAL MARKERS; CROSS-OVER STUDIES; ENVIRONMENTAL EXPOSURE; FEMALE; FOOD CONTAMINATION; FOOD, FORMULATED; HUMANS; MALE; MIDDLE AGED; TASTE; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84880515547     PISSN: 1354750X     EISSN: 13665804     Source Type: Journal    
DOI: 10.3109/1354750X.2013.798031     Document Type: Article

References (38)

1. Afriyie-Gyawu E, Ankrah NA, Huebner HJ, et al. (2008). NovaSil clay intervention in Ghanaians at high risk for aflatoxicosis. I. Study design and clinical outcomes. Food Addit Contam, Part A 25:76-87.
2. Cotty PJ, Jaime-Garcia R. (2007). Influences of climate on aflatoxin producing fungi and aflatoxin contamination. Int J Food Microbiol 119:109-15.
3. Egal S, Hounsa A, Gong YY, et al. (2005). Dietary exposure to aflatoxin from maize and groundnut in young children from Benin and Togo, West Africa. Int J Food Microbiol 104:215-24.
4. Egner PA, Wang JB, Zhu YR, et al. (2001). Chlorophyllin intervention reduces aflatoxin-DNA adducts in individuals at high risk for liver cancer. Proc Natl Acad Sci USA 98:14601-6.
5. Ferlay J, Shin H, Bray F, et al. (2010). Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 127:2893-917.
6. Gan LS, Skipper PL, Peng XC, et al. (1988). Serum albumin adducts in the molecular epidemiology of aflatoxin carcinogenesis: correlation with aflatoxin B1 intake and urinary excretion of aflatoxin M1. Carcinogenesis 9:1323-5.
7. Gong Y, Hounsa A, Egal S, et al. (2004). Postweaning exposure to aflatoxin results in impaired child growth: a longitudinal study in Benin, West Africa. Environ Health Perspect 112:1334-8.
8. Gong YY, Cardwell K, Hounsa A, et al. (2002). Dietary aflatoxin exposure and impaired growth in young children from Benin and Togo: cross sectional study. BMJ 325:20-1.
9. Grant PG, Phillips TD. (1998). Isothermal adsorption of aflatoxin B(1) on HSCAS clay. J Agric Food Chem 46:599-605.
10. Groopman JD, Donahue PR, Zhu JQ, et al. (1985). Aflatoxin metabolism in humans: detection of metabolites and nucleic acid adducts in urine by affinity chromatography. Proc Natl Acad Sci USA 82:6492-6.
11. Groopman JD, Hall AJ, Whittle H, et al. (1992a). Molecular dosimetry of aflatoxin-N7-guanine in human urine obtained in the Gambia, West Africa. Cancer Epidemiol Biomarkers Prev 1:221-7.
12. Groopman JD, Hasler JA, Trudel LJ, et al. (1992b). Molecular dosimetry in rat urine of aflatoxin-N7-guanine and other aflatoxin metabolites by multiple monoclonal antibody affinity chromatography and immunoaffinity/ high performance liquid chromatography. Cancer Res 52: 267-74.
13. Groopman JD, Kensler TW. (1993). Molecular biomarkers for human chemical carcinogen exposures. Chem Res Toxicol 6:764-70.
14. Groopman JD, Kensler TW, Wild CP. (2008). Protective interventions to prevent aflatoxin-induced carcinogenesis in developing countries. Ann Rev Public Health 29:187-203.
15. Groopman JD, Wang JS, Scholl P. (1996). Molecular biomarkers for aflatoxins: from adducts to gene mutations to human liver cancer. Can J Physiol Pharmacol 74:203-9.
16. Groopman JD, Wogan GN, Roebuck BD, Kensler TW. (1994). Molecular biomarkers for aflatoxins and their application to human cancer prevention. Cancer Res 54:1907s-11s.
17. Hinton DM, Myers MJ, Raybourne RA, et al. (2003). Immunotoxicity of aflatoxin B1 in rats: effects on lymphocytes and the inflammatory response in a chronic intermittent dosing study. Toxicol Sci 73: 362-77.
18. IAfRoC. (1993). Some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins. IARC Monogr Eval Carcinog Risks Hum 56:207-71.
19. IAfRoC. (2002). Some traditional herbal medicines, some mycotoxins, napthalene and styrene. IARC Monogr Eval Carcinog Risks Hum 82:171-274.
20. Jolly P, Jiang Y, Ellis W, et al. (2006). Determinants of aflatoxin levels in Ghanaians: sociodemographic factors, knowledge of aflatoxin and food handling and consumption practices. Int J Hyg Environ Health 209:345-58.
21. Kubena LF, Harvey RB, Bailey RH, et al. (1998). Effects of a hydrated sodium calcium aluminosilicate (T-Bind) on mycotoxicosis in young broiler chickens. Poult Sci 77:1502-9.
22. Ledoux DR, Rottinghaus GE, Bermudez AJ, Alonso-Debolt M. (1999). Efficacy of a hydrated sodium calcium aluminosilicate to ameliorate the toxic effects of aflatoxin in broiler chicks. Poult Sci 78:204-10.
23. Marroquin-Cardona A, Deng Y, Garcia-Mazcorro J, et al. (2011). Characterization and safety of uniform particle size NovaSil clay as a potential aflatoxin enterosorbent. Appl Clay Sci 54:248-57.
24. Marroquin-Cardona A, Deng Y, Taylor JF, et al. (2009). In vitro and in vivo characterization of mycotoxin-binding additives used for animal feeds in Mexico. Food Addit Contam Part A 26:733-43.
25. Pestka JJ, Bondy GS. (1990). Alteration of immune function following dietary mycotoxin exposure. Can J Physiol Pharmacol 68:1009-16.
26. Phillips TD, Clement BA, Kubena LF, Harvey RB. (1990). Detection and detoxification of aflatoxins: prevention of aflatoxicosis and aflatoxin residues with hydrated sodium calcium aluminosilicate. Vet Hum Toxicol 32(Suppl):15-19.
27. Pimpukdee K, Kubena LF, Bailey CA, et al. (2004). Aflatoxin-induced toxicity and depletion of hepatic vitamin A in young broiler chicks: protection of chicks in the presence of low levels of NovaSil PLUS in the diet. Poult Sci 83:737-44.
28. Qian GS, Ross RK, Yu MC, et al. (1994). A follow-up study of urinary markers of aflatoxin exposure and liver cancer risk in Shanghai, People's Republic of China. Cancer Epidemiol Biomarkers Prev 3: 3-10.
29. Sarr AB, Mayura K, Kubena LF, et al. (1995). Effects of phyllosilicate clay on the metabolic profile of aflatoxin B1 in Fischer-344 rats. Toxicol Lett 75:145-51.
30. Schell TC, Lindemann MD, Kornegay ET, Blodgett DJ. (1993). Effects of feeding aflatoxin-contaminated diets with and without clay to weanling and growing pigs on performance, liver function, and mineral metabolism. J Anim Sci 71:1209-18.
31. Turner PC, Collinson AC, Cheung YB, et al. (2007). Aflatoxin exposure in utero causes growth faltering in Gambian infants. Int J Epidemiol 36:1119-25.
32. Turner PC, Moore SE, Hall AJ, et al. (2003). Modification of immune function through exposure to dietary aflatoxin in Gambian children. Environ Health Perspect 111:217-20.
33. Wang JS, Shen X, He X, et al. (1999). Protective alterations in phase 1 and 2 metabolism of aflatoxin B1 by oltipraz in residents of Qidong, People's Republic of China. J Natl Cancer Inst 91:347-54.
34. Wang P, Afriyie-Gyawu E, Tang Y, et al. (2008). NovaSil clay intervention in Ghanaians at high risk for aflatoxicosis: II. Reduction in biomarkers of aflatoxin exposure in blood and urine. Food Addit Contam Part A 25:622-34.
35. Wild CP, Turner PC. (2002). The toxicology of aflatoxins as a basis for public health decisions. Mutagenesis 17:471-81.
36. Williams JH, Phillips TD, Jolly PE, et al. (2004). Human aflatoxicosis in developing countries: a review of toxicology, exposure, potential health consequences, and interventions. Am J Clin Nutr 80:1106-22.
37. Wiredu EK, Armah HB. (2006). Cancer mortality patterns in Ghana: a 10-year review of autopsies and hospital mortality. BMC Public Health 6:159.
38. Zhu JQ, Zhang LS, Hu X, et al. (1987). Correlation of dietary aflatoxin B1 levels with excretion of aflatoxin M1 in human urine. Cancer Res 47:1848-52.