TORC1 signaling inhibition by rapamycin and caffeine affect lifespan, global gene expression, and cell proliferation of fission yeast

Aging Cell

Volumn 12, Issue 4, 2013, Pages 563-573

  Rallis, Charalampos ^a   Codlin, Sandra ^a   Bähler, Jürg ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cell proliferation; Chronological aging; Gene regulation; Schizosaccharomyces pombe; Target of Rapamycin; Translation

Indexed keywords

CAFFEINE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; NITROGEN; RAPAMYCIN; CULTURE MEDIUM; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; PHOSPHATIDYLINOSITOL 3 KINASE; SCHIZOSACCHAROMYCES POMBE PROTEIN; TARGET OF RAPAMYCIN KINASE; TOR2 PROTEIN, S POMBE;

ARTICLE; CELL DIVISION; CELL GROWTH; CELL PROLIFERATION; CHRONOLOGICAL LIFESPAN; CONTROLLED STUDY; FISSION YEAST; GENE EXPRESSION; GROWTH CURVE; LIFESPAN; NONHUMAN; NUCLEAR REPROGRAMMING; PH; PHENOTYPE; PRIORITY JOURNAL; RNA TRANSLATION; YEAST; ANTAGONISTS AND INHIBITORS; CULTURE MEDIUM; DRUG EFFECTS; FUNGAL GENE; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MICROBIAL SENSITIVITY TEST; MICROBIAL VIABILITY; PROTEIN SYNTHESIS; SCHIZOSACCHAROMYCES; SIGNAL TRANSDUCTION; TIME;

SCHIZOSACCHAROMYCES POMBE; SCHIZOSACCHAROMYCETACEAE;

CAFFEINE; CELL PROLIFERATION; CULTURE MEDIA; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; HYDROGEN-ION CONCENTRATION; MICROBIAL SENSITIVITY TESTS; MICROBIAL VIABILITY; MULTIPROTEIN COMPLEXES; NITROGEN; PHENOTYPE; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN BIOSYNTHESIS; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS; SIGNAL TRANSDUCTION; SIROLIMUS; TIME FACTORS; TOR SERINE-THREONINE KINASES;

EID: 84880513351     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12080     Document Type: Article

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