BMP-2 peptide-functionalized nanopatterned substrates for enhanced osteogenic differentiation of human mesenchymal stem cells

Biomaterials

Volumn 34, Issue 30, 2013, Pages 7236-7246

  Kim, Mun Jung ^a   Lee, Bora ^b   Yang, Kisuk ^a   Park, Junyong ^b   Jeon, Seokwoo ^b   Um, Soong Ho ^c   Kim, Dong Ik ^d   Im, Sung Gap ^b   Cho, Seung Woo ^a  

^a Yonsei University   (South Korea)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^c Sungkyunkwan University   (South Korea)

^d Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

Bone morphogenetic protein 2; Human mesenchymal stem cells; Initiated chemical vapor deposition; Nanopatterned substrate; Osteogenic differentiation

Indexed keywords

BONE MORPHOGENETIC PROTEIN-2; HUMAN MESENCHYMAL STEM CELLS; INITIATED CHEMICAL VAPOR DEPOSITIONS; NANOPATTERNED SUBSTRATES; OSTEOGENIC DIFFERENTIATION;

ACRYLIC MONOMERS; CELL CULTURE; CHEMICAL VAPOR DEPOSITION; PEPTIDES; POLYMERASE CHAIN REACTION; STEM CELLS; VAPORS;

SUBSTRATES;

ALIZARIN RED S; BONE MORPHOGENETIC PROTEIN 2; NANOMATERIAL;

ARTICLE; BONE DEVELOPMENT; CELL DIFFERENTIATION; CELL STRUCTURE; CHEMICAL COMPOSITION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MESENCHYMAL STEM CELL; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN IMMOBILIZATION; REAL TIME POLYMERASE CHAIN REACTION; SURFACE PROPERTY;

BONE MORPHOGENETIC PROTEIN-2; HUMAN MESENCHYMAL STEM CELLS; INITIATED CHEMICAL VAPOR DEPOSITION; NANOPATTERNED SUBSTRATE; OSTEOGENIC DIFFERENTIATION;

AMINO ACID SEQUENCE; BONE MORPHOGENETIC PROTEIN 2; CELL DIFFERENTIATION; FOCAL ADHESIONS; HUMANS; IMMOBILIZED PROTEINS; MESENCHYMAL STROMAL CELLS; MOLECULAR SEQUENCE DATA; NANOPARTICLES; OSTEOGENESIS; PEPTIDES; PHOTOELECTRON SPECTROSCOPY; POLYMETHACRYLIC ACIDS; POLYURETHANES;

EID: 84880507834     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.06.019     Document Type: Article

References (52)

1. Cukierman E., Pankov R., Stevens D.R., Yamada K.M. Taking cell-matrix adhesions to the third dimension. Science 2001, 294:1708-1712.
2. Oh S., Brammer K.S., Li Y.S., Teng D., Engler A.J., Chien S., et al. Stem cell fate dictated solely by altered nanotube dimension. Proc Natl Acad Sci U S A 2009, 106:2130-2135.
3. Engler A.J., Sen S., Sweeney H.L., Discher D.E. Matrix elasticity directs stem cell lineage specification. Cell 2006, 126:677-689.
4. Cameron A.R., Frith J.E., Cooper-White J.J. The influence of substrate creep on mesenchymal stem cell behaviour and phenotype. Biomaterials 2011, 32:5979-5993.
5. Trappmann B., Gautrot J.E., Connelly J.T., Strange D.G., Li Y., Oyen M.L., et al. Extracellular-matrix tethering regulates stem-cell fate. Nat Mater 2012, 11:642-649.
6. Dalby M.J., Gadegaard N., Tare R., Andar A., Riehle M.O., Herzyk P., et al. The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder. Nat Mater 2007, 6:997-1003.
7. Teo B.K., Ankam S., Chan L.Y., Yim E.K. Nanotopography/mechanical induction of stem-cell differentiation. Methods Cell Biol 2010, 98:241-294.
8. Kim H.N., Jiao A., Hwang N.S., Kim M.S., Kang do H., Kim D.H., et al. Nanotopography-guided tissue engineering and regenerative medicine. Adv Drug Deliv Rev 2013, 65:536-558.
9. Lutolf M.P., Blau H.M. Artificial stem cell niches. Adv Mater 2009, 21:3255-3268.
10. Kim D.H., Provenzano P.P., Smith C.L., Levchenko A. Matrix nanotopography as a regulator of cell function. JCell Biol 2012, 197:351-360.
11. Kim H.N., Hong Y., Kim M.S., Kim S.M., Suh K.Y. Effect of orientation and density of nanotopography in dermal wound healing. Biomaterials 2012, 33:8782-8792.
12. Lee M.R., Kwon K.W., Jung H., Kim H.N., Suh K.Y., Kim K., et al. Direct differentiation of human embryonic stem cells into selective neurons on nanoscale ridge/groove pattern arrays. Biomaterials 2010, 31:4360-4366.
13. Jeon K., Oh H.J., Lim H., Kim J.H., Lee D.H., Lee E.R., et al. Self-renewal of embryonic stem cells through culture on nanopattern polydimethylsiloxane substrate. Biomaterials 2012, 33:5206-5220.
14. McMurray R.J., Gadegaard N., Tsimbouri P.M., Burgess K.V., McNamara L.E., Tare R., et al. Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency. Nat Mater 2011, 10:637-644.
15. Yim E.K., Pang S.W., Leong K.W. Synthetic nanostructures inducing differentiation of human mesenchymal stem cells into neuronal lineage. Exp Cell Res 2007, 313:1820-1829.
16. Watari S., Hayashi K., Wood J.A., Russell P., Nealey P.F., Murphy C.J., et al. Modulation of osteogenic differentiation in hMSCs cells by submicron topographically-patterned ridges and grooves. Biomaterials 2012, 33:128-136.
17. Love J.C., Estroff L.A., Kriebel J.K., Nuzzo R.G., Whitesides G.M. Self-assembled monolayers of thiolates on metals as a form of nanotechnology. Chem Rev 2005, 105:1103-1169.
18. Jonkheijm P., Weinrich D., Schroder H., Niemeyer C.M., Waldmann H. Chemical strategies for generating protein biochips. Angew Chem Int Ed Engl 2008, 47:9618-9647.
19. Rusmini F., Zhong Z., Feijen J. Protein immobilization strategies for protein biochips. Biomacromolecules 2007, 8:1775-1789.
20. Mei Y., Saha K., Bogatyrev S.R., Yang J., Hook A.L., Kalcioglu Z.I., et al. Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells. Nat Mater 2010, 9:768-778.
21. Im S.G., Gleason K.K. Solvent-free modification of surfaces with polymers: the case for initiated and oxidative chemical vapor deposition (CVD). AIChE J 2011, 57:276-285.
22. Sreenivasan R., Gleason K.K. Overview of strategies for the CVD of organic films and functional polymer layers. Chem Vapor Depos 2009, 15:77-90.
23. Alf M.E., Asatekin A., Barr M.C., Baxamusa S.H., Chelawat H., Ozaydin-Ince G., et al. Chemical vapor deposition of conformal, functional, and responsive polymer films. Adv Mater 2010, 22:1993-2027.
24. Asatekin A., Barr M.C., Baxamusa S.H., Lau K.K.S., Tenhaeff W., Xu J., et al. Designing polymer surfaces via vapor deposition. Mater Today 2010, 13:26-33.
25. Baxamusa S.H., Im S.G., Gleason K.K. Initiated and oxidative chemical vapor deposition: a scalable method for conformal and functional polymer films on real substrates. Phys Chem Chem Phys 2009, 11:5227-5240.
26. Lau K.K.S., Gleason K.K. Initiated chemical vapor deposition (iCVD) of poly (alkyl acrylates): an experimental study. Macromolecules 2006, 39:3688-3694.
27. Tenhaeff W.E., Gleason K.K. Initiated and oxidative chemical vapor deposition of polymeric thin films: iCVD and oCVD. Adv Funct Mater 2008, 18:979-992.
28. Im S.G., Bong K.W., Lee C.H., Doyle P.S., Gleason K.K. Aconformal nano-adhesive via initiated chemical vapor deposition for microfluidic devices. Lab Chip 2008, 9:411-416.
29. Im S.G., Kim B.S., Lee L.H., Tenhaeff W.E., Hammond P.T., Gleason K.K. Adirectly patternable, click-active polymer film via initiated chemical vapor deposition. Macromol Rapid Commun 2008, 29:1648-1654.
30. Im S.G., Kim B.S., Tenhaeff W.E., Hammond P.T., Gleason K.K. Adirectly patternable click-active polymer film via initiated chemical vapor deposition (iCVD). Thin Solid Films 2009, 517:3606-3611.
31. Pittenger M.F., Mackay A.M., Beck S.C., Jaiswal R.K., Douglas R., Mosca J.D., et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999, 284:143-147.
32. Yang F., Cho S.W., Son S.M., Bogatyrev S.R., Singh D., Green J.J., et al. Genetic engineering of human stem cells for enhanced angiogenesis using biodegradable polymeric nanoparticles. Proc Natl Acad Sci U S A 2010, 107:3317-3322.
33. Lee J.S., Wagoner-Johnson A., Murphy W.L. Modular peptide growth factors for substrate-mediated stem cell differentiation. Angew Chem Int Ed Engl 2009, 48:6266-6269.
34. Yang K., Lee J.S., Kim J., Lee Y.B., Shin H., Um S.H., et al. Polydopamine-mediated surface modification of scaffold materials for human neural stem cell engineering. Biomaterials 2012, 33:6952-6964.
35. Choi S.J., Yoo P.J., Baek S.J., Kim T.W., Lee H.H. An ultraviolet-curable mold for sub-100-nm lithography. JAm Chem Soc 2004, 126:7744-7745.
36. Choi S.J., Kim H.N., Bae W.G., Suh K.Y. Modulus-and surface energy-tunable ultraviolet-curable polyurethane acrylate: properties and applications. JMater Chem 2011, 21:14325-14335.
37. Yoo P.J., Choi S.J., Kim J.H., Suh D., Baek S.J., Kim T.W., et al. Unconventional patterning with a modulus-tunable mold: from imprinting to microcontact printing. Chem Mater 2004, 16:5000-5005.
38. Jang H.I., Ko S., Park J., Lee D.E., Jeon S., Ahn C.W., et al. Reversible creation of nanostructures between identical or different species of materials. Appl Phys A-Mater 2012, 108:41-52.
39. Park J., Park J.H., Kim E., Ahn C.W., Jang H.I., Rogers J.A., et al. Conformable solid-index phase masks composed of high-aspect-ratio micropillar arrays and their application to 3D nanopatterning. Adv Mater 2011, 23:860-864.
40. You M.H., Kwak M.K., Kim D.H., Kim K., Levchenko A., Kim D.Y., et al. Synergistically enhanced osteogenic differentiation of human mesenchymal stem cells by culture on nanostructured surfaces with induction media. Biomacromolecules 2010, 11:1856-1862.
41. Saito A., Suzuki Y., Ogata S., Ohtsuki C., Tanihara M. Accelerated bone repair with the use of a synthetic BMP-2-derived peptide and bone-marrow stromal cells. JBiomed Mater Res A 2005, 72:77-82.
42. Li S.C., Songyang Z., Vincent S.J., Zwahlen C., Wiley S., Cantley L., et al. High-affinity binding of the Drosophila Numb phosphotyrosine-binding domain to peptides containing a Gly-Pro-(p)Tyr motif. Proc Natl Acad Sci U S A 1997, 94:7204-7209.
43. Thierry B., Jasieniak M., de Smet L.C., Vasilev K., Griesser H.J. Reactive epoxy-functionalized thin films by a pulsed plasma polymerization process. Langmuir 2008, 24:10187-10195.
44. Jaiswal N., Haynesworth S.E., Caplan A.I., Bruder S.P. Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells invitro. JCell Biochem 1997, 64:295-312.
45. Anderson H.C. Mechanism of mineral formation in bone. Lab Invest 1989, 60:320-330.
46. Yim E.K., Darling E.M., Kulangara K., Guilak F., Leong K.W. Nanotopography-induced changes in focal adhesions, cytoskeletal organization, and mechanical properties of human mesenchymal stem cells. Biomaterials 2010, 31:1299-1306.
47. Seo C.H., Furukawa K., Montagne K., Jeong H., Ushida T. The effect of substrate microtopography on focal adhesion maturation and actin organization via the RhoA/ROCK pathway. Biomaterials 2011, 32:9568-9575.
48. Chalut K.J., Kulangara K., Giacomelli M.G., Wax A., Leong K.W. Deformation of stem cell nuclei by nanotopographical cues. Soft Matter 2010, 6:1675-1681.
49. Kadler K.E., Holmes D.F., Trotter J.A., Chapman J.A. Collagen fibril formation. Biochem J 1996, 316(Pt 1):1-11.
50. Leboy P.S., Beresford J.N., Devlin C., Owen M.E. Dexamethasone induction of osteoblast mRNAs in rat marrow stromal cell cultures. JCell Physiol 1991, 146:370-378.
51. Seo C.H., Jeong H., Furukawa K.S., Suzuki Y., Ushida T. The switching of focal adhesion maturation sites and actin filament activation for MSCs by topography of well-defined micropatterned surfaces. Biomaterials 2013, 34:1764-1771.
52. Kulangara K., Yang Y., Yang J., Leong K.W. Nanotopography as modulator of human mesenchymal stem cell function. Biomaterials 2012, 33:4998-5003.