메뉴 건너뛰기




Volumn 434, Issue 3, 2013, Pages 413-420

Mechanisms of G1 cell cycle arrest and apoptosis in myeloma cells induced by hybrid-compound histone deacetylase inhibitor

Author keywords

Apoptosis; Cell cycle; Histone deacetylase inhibitor; Myeloma cell

Indexed keywords

CASPASE 9; HISTONE DEACETYLASE INHIBITOR; HISTONE H3; KY 2; UNCLASSIFIED DRUG;

EID: 84880475894     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.03.043     Document Type: Article
Times cited : (16)

References (35)
  • 1
    • 0038305911 scopus 로고    scopus 로고
    • Multicenter phase 2 trial of thalidomide in relapsed/refractory multiple myeloma: Adverse prognostic impact of advanced age
    • L. Mileshkin, J.J. Biagi, P. Mitchell, C. Underhil, A. Grigg, R. Bell, et al., Multicenter phase 2 trial of thalidomide in relapsed/refractory multiple myeloma: adverse prognostic impact of advanced age, Blood 102 (2003) 69-77.
    • (2003) Blood , vol.102 , pp. 69-77
    • Mileshkin, L.1    Biagi, J.J.2    Mitchell, P.3    Underhil, C.4    Grigg, A.5    Bell, R.6
  • 3
    • 0036739745 scopus 로고    scopus 로고
    • Clinical activity of arsenic trioxide for the treatment of multiple myeloma
    • N.C. Munshi, G. Tricot, R. Desikan, A. Badros, M. Zangari, A. Toor, et al., Clinical activity of arsenic trioxide for the treatment of multiple myeloma, Leukemia 16 (2002) 1835-1837.
    • (2002) Leukemia , vol.16 , pp. 1835-1837
    • Munshi, N.C.1    Tricot, G.2    Desikan, R.3    Badros, A.4    Zangari, M.5    Toor, A.6
  • 4
    • 0001790293 scopus 로고    scopus 로고
    • Histone deacetylases and transcriptional therapy with their inhibitors
    • P.P. Pandolfi, Histone deacetylases and transcriptional therapy with their inhibitors, Cancer Chemother. Pharmacol. 48 (2001) 17-19.
    • (2001) Cancer Chemother. Pharmacol. , vol.48 , pp. 17-19
    • Pandolfi, P.P.1
  • 7
    • 0036216505 scopus 로고    scopus 로고
    • Epigenomics and epigenetic therapy of cancer
    • R. Brown, G. Strathdee, Epigenomics and epigenetic therapy of cancer, Trends Mol. Med. 8 (2002) 43-48.
    • (2002) Trends Mol. Med. , vol.8 , pp. 43-48
    • Brown, R.1    Strathdee, G.2
  • 8
    • 0033523203 scopus 로고    scopus 로고
    • Chromatin remodeling and transcriptional regulation
    • R.X. Luo, D.C. Dean, Chromatin remodeling and transcriptional regulation, J. Natl. Cancer Inst. 91 (1999) 1288-1294.
    • (1999) J. Natl. Cancer Inst. , vol.91 , pp. 1288-1294
    • Luo, R.X.1    Dean, D.C.2
  • 9
    • 0035793107 scopus 로고    scopus 로고
    • Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin
    • R. Furumai, Y. Komatsu, N. Nishino, S. Khochbin, M. Yoshida, S. Horinouchi, Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin, Proc. Natl. Acad. Sci. USA 98 (2001) 87-92.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 87-92
    • Furumai, R.1    Komatsu, Y.2    Nishino, N.3    Khochbin, S.4    Yoshida, M.5    Horinouchi, S.6
  • 10
    • 79251566746 scopus 로고    scopus 로고
    • Physical and functional HAT/HDAC interplay regulates protein acetylation balance
    • A. Peserico, C. Simone, Physical and functional HAT/HDAC interplay regulates protein acetylation balance, J. Biomed. Biotechnol. (2011), http://dx.doi.org/ 10.11155/2011/371832.
    • (2011) J. Biomed. Biotechnol.
    • Peserico, A.1    Simone, C.2
  • 11
    • 33645310174 scopus 로고    scopus 로고
    • Defining the role of gene regulation in resistance to HDAC inhibitors-mechanisms beyond P-glycoprotein
    • K.B. Glaser, Defining the role of gene regulation in resistance to HDAC inhibitors-mechanisms beyond P-glycoprotein, Leuk. Res. 30 (2006) 651-652.
    • (2006) Leuk. Res. , vol.30 , pp. 651-652
    • Glaser, K.B.1
  • 12
    • 0842277812 scopus 로고    scopus 로고
    • Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1
    • C.Y. Gui, L. Ngo, W.S. Xu, V.M. Richon, P.A. Marks, Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1, Proc. Natl. Acad. Sci. USA 101 (2004) 1241-1246.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 1241-1246
    • Gui, C.Y.1    Ngo, L.2    Xu, W.S.3    Richon, V.M.4    Marks, P.A.5
  • 13
    • 0036527775 scopus 로고    scopus 로고
    • Histone-deacetylase inhibitors: Novel drugs for the treatment of cancer
    • R.W. Johnstone, Histone-deacetylase inhibitors: novel drugs for the treatment of cancer, Nat. Rev. Drug Discov. 1 (2002) 287-299.
    • (2002) Nat. Rev. Drug Discov. , vol.1 , pp. 287-299
    • Johnstone, R.W.1
  • 15
    • 0033520944 scopus 로고    scopus 로고
    • Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects
    • L.C. Sambucetti, D.D. Fischer, S. Zabludoff, P.O. Kwon, H. Chamberlin, N. Trogani, et al., Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects, J. Biol. Chem. 274 (1999) 34940-34947.
    • (1999) J. Biol. Chem. , vol.274 , pp. 34940-34947
    • Sambucetti, L.C.1    Fischer, D.D.2    Zabludoff, S.3    Kwon, P.O.4    Chamberlin, H.5    Trogani, N.6
  • 16
    • 0034770423 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors increase p21 (WAF1) and induce apoptosis of human myeloma cell lines independent of decreased IL-6 receptor expression
    • D. Lavelle, Y.H. Chen, M. Hankewych, J. DeSimone, Histone deacetylase inhibitors increase p21 (WAF1) and induce apoptosis of human myeloma cell lines independent of decreased IL-6 receptor expression, Am. J. Hematol. 68 (2001) 170-178.
    • (2001) Am. J. Hematol. , vol.68 , pp. 170-178
    • Lavelle, D.1    Chen, Y.H.2    Hankewych, M.3    DeSimone, J.4
  • 18
    • 0029055087 scopus 로고
    • Induction of apoptosis in B lineage cells by activin A derived from macrophages
    • T. Nishihara, Y. Ohsaki, N. Ueda, T. Koseki, Y. Eto, Induction of apoptosis in B lineage cells by activin A derived from macrophages, J. Interferon Cytokine Res. 15 (1995) 509-516.
    • (1995) J. Interferon Cytokine Res. , vol.15 , pp. 509-516
    • Nishihara, T.1    Ohsaki, Y.2    Ueda, N.3    Koseki, T.4    Eto, Y.5
  • 19
    • 1842631408 scopus 로고    scopus 로고
    • Upregulation and nuclear recruitment of HDAC1 in hormone refractory prostate cancer
    • K. Halkidou, L. Gaughan, S. Cook, H.Y. Leung, D.E. Neal, C.N. Robson, Upregulation and nuclear recruitment of HDAC1 in hormone refractory prostate cancer, Prostate 59 (2004) 177-189.
    • (2004) Prostate , vol.59 , pp. 177-189
    • Halkidou, K.1    Gaughan, L.2    Cook, S.3    Leung, H.Y.4    Neal, D.E.5    Robson, C.N.6
  • 20
    • 17144378591 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase 2 increases apoptosis and p21Cip1/WAF1 expression, independent of histone deacetylase 1
    • B.H. Huang, M. Laban, C.H. Leung, L. Lee, C.K. Lee, M. Salto-Tellez, et al., Inhibition of histone deacetylase 2 increases apoptosis and p21Cip1/WAF1 expression, independent of histone deacetylase 1, Cell Death Differ. 12 (2005) 395-404.
    • (2005) Cell Death Differ. , vol.12 , pp. 395-404
    • Huang, B.H.1    Laban, M.2    Leung, C.H.3    Lee, L.4    Lee, C.K.5    Salto-Tellez, M.6
  • 21
    • 21044447215 scopus 로고    scopus 로고
    • Increased expression of histone deacetylase 2 is found in human gastric cancer
    • J. Song, J.H. Noh, J.H. Lee, J.W. Eun, Y.M. Ahn, S.Y. Kim, et al., Increased expression of histone deacetylase 2 is found in human gastric cancer, APMIS 113 (2005) 264-268.
    • (2005) APMIS , vol.113 , pp. 264-268
    • Song, J.1    Noh, J.H.2    Lee, J.H.3    Eun, J.W.4    Ahn, Y.M.5    Kim, S.Y.6
  • 22
    • 33749572938 scopus 로고    scopus 로고
    • Valproate inhibition of histone deacetylase 2 affects differentiation and decreases proliferation of endometrial stromal sarcoma cells
    • A. Hrzenjak, F. Moinfar, M.L. Kremser, B. Strohmeier, P.B. Staber, K. Zatloukal, et al., Valproate inhibition of histone deacetylase 2 affects differentiation and decreases proliferation of endometrial stromal sarcoma cells, Mol. Cancer Ther. 5 (2006) 2203-2210.
    • (2006) Mol. Cancer Ther. , vol.5 , pp. 2203-2210
    • Hrzenjak, A.1    Moinfar, F.2    Kremser, M.L.3    Strohmeier, B.4    Staber, P.B.5    Zatloukal, K.6
  • 23
    • 67349232016 scopus 로고    scopus 로고
    • Valproic acid exerts anti-tumor as well as anti-angiogenic effects on myeloma
    • K. Kitazoe, M. Abe, M. Hiasa, A. Oda, H. Amou, T. Harada, et al., Valproic acid exerts anti-tumor as well as anti-angiogenic effects on myeloma, Int. J. Hematol. 89 (2009) 45-57.
    • (2009) Int. J. Hematol. , vol.89 , pp. 45-57
    • Kitazoe, K.1    Abe, M.2    Hiasa, M.3    Oda, A.4    Amou, H.5    Harada, T.6
  • 24
    • 3242765335 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors-a new tool to treat cancer
    • R. Somech, S. Izraeli, S.J. Simon, Histone deacetylase inhibitors-a new tool to treat cancer, Cancer Treat. Rev. 30 (2004) 461-472.
    • (2004) Cancer Treat. Rev. , vol.30 , pp. 461-472
    • Somech, R.1    Izraeli, S.2    Simon, S.J.3
  • 25
    • 77955871803 scopus 로고    scopus 로고
    • Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in multiple myeloma
    • J. Kikuchi, T. Wada, R. Shimizu, T. Izumi, M. Akutsu, K. Mitsunaga, et al., Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in multiple myeloma, Blood 116 (2010) 406-417.
    • (2010) Blood , vol.116 , pp. 406-417
    • Kikuchi, J.1    Wada, T.2    Shimizu, R.3    Izumi, T.4    Akutsu, M.5    Mitsunaga, K.6
  • 26
    • 0035361402 scopus 로고    scopus 로고
    • Cyclic hydroxamic-acid-containing peptide 31, a potent synthetic histone deacetylase inhibitor with antitumor activity
    • Y. Komatsu, K.Y. Tomizaki, M. Tsukamoto, T. Kato, N. Nishino, S. Sato, et al., Cyclic hydroxamic-acid-containing peptide 31, a potent synthetic histone deacetylase inhibitor with antitumor activity, Cancer Res. 61 (2001) 4459-4466.
    • (2001) Cancer Res. , vol.61 , pp. 4459-4466
    • Komatsu, Y.1    Tomizaki, K.Y.2    Tsukamoto, M.3    Kato, T.4    Nishino, N.5    Sato, S.6
  • 27
    • 4143140016 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors open new doors in cancer therapy
    • F. McLaughlin, N.B. La Thangue, Histone deacetylase inhibitors open new doors in cancer therapy, Biochem. Pharmacol. 68 (2004) 1139-1144.
    • (2004) Biochem. Pharmacol. , vol.68 , pp. 1139-1144
    • McLaughlin, F.1    La Thangue, N.B.2
  • 28
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • R.A. Weinberg, The retinoblastoma protein and cell cycle control, Cell 81 (1995) 323-330.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 29
    • 0025819962 scopus 로고
    • Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle
    • H. Matsushime, M.F. Roussel, R.A. Ashmun, C.J. Sherr, Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle, Cell 65 (1991) 701-713.
    • (1991) Cell , vol.65 , pp. 701-713
    • Matsushime, H.1    Roussel, M.F.2    Ashmun, R.A.3    Sherr, C.J.4
  • 30
    • 0033822112 scopus 로고    scopus 로고
    • P21-dependent G1 arrest with downregulation of cyclin D1 and upregulation of cyclin E by the histone deacetylase inhibitor FR901228
    • V. Sandor, A. Senderowicz, S. Mertins, D. Sackett, E. Sausville, M.V. Blagosklonny, et al., P21-dependent G1 arrest with downregulation of cyclin D1 and upregulation of cyclin E by the histone deacetylase inhibitor FR901228, Br. J. Cancer 83 (2000) 817-825.
    • (2000) Br. J. Cancer , vol.83 , pp. 817-825
    • Sandor, V.1    Senderowicz, A.2    Mertins, S.3    Sackett, D.4    Sausville, E.5    Blagosklonny, M.V.6
  • 31
    • 23244459828 scopus 로고    scopus 로고
    • Interactive effects of HDAC inhibitors and TRAIL on apoptosis are associated with changes in mitochondrial functions and expressions of cell cycle regulatory genes in multiple myeloma
    • T.E. Fandy, S. Shankar, D.D. Ross, E. Sausville, R.K. Srivastava, Interactive effects of HDAC inhibitors and TRAIL on apoptosis are associated with changes in mitochondrial functions and expressions of cell cycle regulatory genes in multiple myeloma, Neoplasia 7 (2005) 646-657.
    • (2005) Neoplasia , vol.7 , pp. 646-657
    • Fandy, T.E.1    Shankar, S.2    Ross, D.D.3    Sausville, E.4    Srivastava, R.K.5
  • 32
    • 0033601746 scopus 로고    scopus 로고
    • Ordering the cytochrome c-initiated caspase cascade: Hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner
    • E.A. Slee, M.T. Harte, R.M. Kluck, B.B. Wolf, C.A. Casiano, D.D. Newmeyer, et al., Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner, J. Cell Biol. 144 (1999) 281-292.
    • (1999) J. Cell Biol. , vol.144 , pp. 281-292
    • Slee, E.A.1    Harte, M.T.2    Kluck, R.M.3    Wolf, B.B.4    Casiano, C.A.5    Newmeyer, D.D.6
  • 33
    • 0034786019 scopus 로고    scopus 로고
    • BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
    • E.H. Cheng, M.C. Wei, S. Weiler, R.A. Flavell, T.W. Mak, T. Lindsten, et al., BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis, Mol. Cell 8 (2001) 705-711.
    • (2001) Mol. Cell , vol.8 , pp. 705-711
    • Cheng, E.H.1    Wei, M.C.2    Weiler, S.3    Flavell, R.A.4    Mak, T.W.5    Lindsten, T.6
  • 34
    • 0033596980 scopus 로고    scopus 로고
    • An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
    • H. Zou, Y. Li, X. Liu, X. Wang, An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9, J. Biol. Chem. 274 (1999) 11549-11556.
    • (1999) J. Biol. Chem. , vol.274 , pp. 11549-11556
    • Zou, H.1    Li, Y.2    Liu, X.3    Wang, X.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.