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Volumn 8, Issue 7, 2013, Pages

MMP-9 and CXCL8/IL-8 Are Potential Therapeutic Targets in Epidermolysis Bullosa Simplex

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CYTOKERATIN; GELATINASE B; INTERLEUKIN 1BETA; INTERLEUKIN 8; JUNCTION PROTEIN; KALLIKREIN; MATRIX METALLOPROTEINASE; PEPTIDASE; PROTEIN CDC42; UNCLASSIFIED DRUG;

EID: 84880465718     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0070123     Document Type: Article
Times cited : (22)

References (43)
  • 2
    • 43449084027 scopus 로고    scopus 로고
    • The classification of inherited epidermolysis bullosa (EB): Report of the third international consensus meeting on diagnosis and classification of EB
    • Fine JD, Eady RA, Bauer EA, Bauer JW, Bruckner-Tuderman L, et al. (2008) The classification of inherited epidermolysis bullosa (EB): Report of the third international consensus meeting on diagnosis and classification of EB. J Am Acad Dermatol 58: 931-950.
    • (2008) J Am Acad Dermatol , vol.58 , pp. 931-950
    • Fine, J.D.1    Eady, R.A.2    Bauer, E.A.3    Bauer, J.W.4    Bruckner-Tuderman, L.5
  • 3
    • 44149099717 scopus 로고    scopus 로고
    • The human keratins: biology and pathology
    • Moll R, Divo M, Langbein L, (2008) The human keratins: biology and pathology. Histochem Cell Biol 129: 705-733.
    • (2008) Histochem Cell Biol , vol.129 , pp. 705-733
    • Moll, R.1    Divo, M.2    Langbein, L.3
  • 4
    • 68849091625 scopus 로고    scopus 로고
    • Epidermolysis bullosa simplex: a paradigm for disorders of tissue fragility
    • Coulombe PA, Kerns ML, Fuchs E, (2009) Epidermolysis bullosa simplex: a paradigm for disorders of tissue fragility. J Clin Invest 119: 1784-1793.
    • (2009) J Clin Invest , vol.119 , pp. 1784-1793
    • Coulombe, P.A.1    Kerns, M.L.2    Fuchs, E.3
  • 5
    • 76649114657 scopus 로고    scopus 로고
    • ERK involvement in resistance to apoptosis in keratinocytes with mutant keratin
    • Russell D, Ross H, Lane EB, (2010) ERK involvement in resistance to apoptosis in keratinocytes with mutant keratin. J Invest Dermatol 130: 671-681.
    • (2010) J Invest Dermatol , vol.130 , pp. 671-681
    • Russell, D.1    Ross, H.2    Lane, E.B.3
  • 6
    • 36248998854 scopus 로고    scopus 로고
    • Induction of inflammatory cytokines by a keratin mutation and their repression by a small molecule in a mouse model for EBS
    • Lu H, Chen J, Planko L, Zigrino P, Klein-Hitpass L, et al. (2007) Induction of inflammatory cytokines by a keratin mutation and their repression by a small molecule in a mouse model for EBS. J Invest Dermatol 127: 2781-2789.
    • (2007) J Invest Dermatol , vol.127 , pp. 2781-2789
    • Lu, H.1    Chen, J.2    Planko, L.3    Zigrino, P.4    Klein-Hitpass, L.5
  • 8
    • 0042635660 scopus 로고    scopus 로고
    • Generation and characterization of epidermolysis bullosa simplex cell lines: scratch assays show faster migration with disruptive keratin mutations
    • Morley SM, D'Alessandro M, Sexton C, Rugg EL, Navsaria H, et al. (2003) Generation and characterization of epidermolysis bullosa simplex cell lines: scratch assays show faster migration with disruptive keratin mutations. Br J Dermatol 149: 46-58.
    • (2003) Br J Dermatol , vol.149 , pp. 46-58
    • Morley, S.M.1    D'Alessandro, M.2    Sexton, C.3    Rugg, E.L.4    Navsaria, H.5
  • 9
    • 18344396568 scopus 로고    scopus 로고
    • Minimum information about a microarray experiment (MIAME)-toward standards for microarray data
    • Brazma A, Hingamp P, Quackenbush J, Sherlock G, Spellman P, et al. (2001) Minimum information about a microarray experiment (MIAME)-toward standards for microarray data. Nature Genetics 29: 365-371.
    • (2001) Nature Genetics , vol.29 , pp. 365-371
    • Brazma, A.1    Hingamp, P.2    Quackenbush, J.3    Sherlock, G.4    Spellman, P.5
  • 10
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang DW, Sherman BT, Lempicki RA, (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4: 44-57.
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 11
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
    • Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 13
    • 2442428082 scopus 로고    scopus 로고
    • Degradation of corneodesmosome proteins by two serine proteases of the kallikrein family, SCTE/KLK5/hK5 and SCCE/KLK7/hK7
    • Caubet C, Jonca N, Brattsand M, Guerrin M, Bernard D, et al. (2004) Degradation of corneodesmosome proteins by two serine proteases of the kallikrein family, SCTE/KLK5/hK5 and SCCE/KLK7/hK7. J Invest Dermatol 122: 1235-1244.
    • (2004) J Invest Dermatol , vol.122 , pp. 1235-1244
    • Caubet, C.1    Jonca, N.2    Brattsand, M.3    Guerrin, M.4    Bernard, D.5
  • 14
    • 0037693895 scopus 로고    scopus 로고
    • Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function and biochemistry
    • Visse R, Nagase H, (2003) Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function and biochemistry. Circ Res 92: 827-839.
    • (2003) Circ Res , vol.92 , pp. 827-839
    • Visse, R.1    Nagase, H.2
  • 15
    • 0033994755 scopus 로고    scopus 로고
    • Collybistin, a newly identified brain-specific GEF, induces submembrane clustering of gephyrin
    • Kins S, Betz H, Kirsch J, (2000) Collybistin, a newly identified brain-specific GEF, induces submembrane clustering of gephyrin. Nat Neurosci 3: 22-29.
    • (2000) Nat Neurosci , vol.3 , pp. 22-29
    • Kins, S.1    Betz, H.2    Kirsch, J.3
  • 17
    • 0031962372 scopus 로고    scopus 로고
    • Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization
    • Leung T, Chen XQ, Tan I, Manser E, Lim L, (1998) Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization. Mol Cell Biol 18: 130-140.
    • (1998) Mol Cell Biol , vol.18 , pp. 130-140
    • Leung, T.1    Chen, X.Q.2    Tan, I.3    Manser, E.4    Lim, L.5
  • 18
    • 0033853336 scopus 로고    scopus 로고
    • Phosphorylation of ERM proteins at filopodia induced by Cdc42
    • Nakamura N, Oshiro N, Fukata Y, Amano M, Fukata M, et al. (2000) Phosphorylation of ERM proteins at filopodia induced by Cdc42. Genes Cells 5: 571-581.
    • (2000) Genes Cells , vol.5 , pp. 571-581
    • Nakamura, N.1    Oshiro, N.2    Fukata, Y.3    Amano, M.4    Fukata, M.5
  • 19
    • 84855679383 scopus 로고    scopus 로고
    • Gene expression analysis of an epidermolysis bullosa simplex Dowling-Meara cell line by subtractive hybridization: recapitulation of cellular differentiation, migration and wound healing
    • Wagner M, Hintner H, Bauer JW, Onder K, (2012) Gene expression analysis of an epidermolysis bullosa simplex Dowling-Meara cell line by subtractive hybridization: recapitulation of cellular differentiation, migration and wound healing. Exp Dermatol 21: 111-117.
    • (2012) Exp Dermatol , vol.21 , pp. 111-117
    • Wagner, M.1    Hintner, H.2    Bauer, J.W.3    Onder, K.4
  • 20
    • 0032809019 scopus 로고    scopus 로고
    • Two familial cases of epidermolysis bullosa simplex successfully treated with tetracycline
    • Retief CR, Malkinson FD, Pearson RW, (1999) Two familial cases of epidermolysis bullosa simplex successfully treated with tetracycline. Arch Dermatol 135: 997-998.
    • (1999) Arch Dermatol , vol.135 , pp. 997-998
    • Retief, C.R.1    Malkinson, F.D.2    Pearson, R.W.3
  • 21
    • 0034097766 scopus 로고    scopus 로고
    • Treatment of epidermolysis bullosa simplex (EBS) with tetracycline
    • Veien NK, Buus SK, (2000) Treatment of epidermolysis bullosa simplex (EBS) with tetracycline. Arch Dermatol 136: 424-425.
    • (2000) Arch Dermatol , vol.136 , pp. 424-425
    • Veien, N.K.1    Buus, S.K.2
  • 22
    • 77956562826 scopus 로고    scopus 로고
    • Tetracyclines: a pleiotropic family of compounds with promising therapeutic properties. Review of the literature
    • Griffin MO, Fricovsky E, Ceballos G, Villarreal F, (2010) Tetracyclines: a pleiotropic family of compounds with promising therapeutic properties. Review of the literature. Am J Physiol Cell Physiol 299: 539-548.
    • (2010) Am J Physiol Cell Physiol , vol.299 , pp. 539-548
    • Griffin, M.O.1    Fricovsky, E.2    Ceballos, G.3    Villarreal, F.4
  • 23
    • 34248232439 scopus 로고    scopus 로고
    • Defining the involvement of proteinases in pemphigus vulgaris: Evidence of matrix metalloproteinase-9 overexpression in experimental models of disease
    • Cirillo N, Lanza M, Rossiello L, Gombos F, Lanza A, (2007) Defining the involvement of proteinases in pemphigus vulgaris: Evidence of matrix metalloproteinase-9 overexpression in experimental models of disease. J Cell Physiol 212: 36-41.
    • (2007) J Cell Physiol , vol.212 , pp. 36-41
    • Cirillo, N.1    Lanza, M.2    Rossiello, L.3    Gombos, F.4    Lanza, A.5
  • 24
    • 0030963694 scopus 로고    scopus 로고
    • A major role for neutrophils in experimental bullous pemphigoid
    • Liu Z, Giudice GJ, Zhou X, Swartz SJ, Troy JL, et al. (1997) A major role for neutrophils in experimental bullous pemphigoid. J Clin Invest 100: 1256-1263.
    • (1997) J Clin Invest , vol.100 , pp. 1256-1263
    • Liu, Z.1    Giudice, G.J.2    Zhou, X.3    Swartz, S.J.4    Troy, J.L.5
  • 25
    • 0035000916 scopus 로고    scopus 로고
    • The IL-8 release from cultured human keratinocytes, mediated by antibodies to bullous pemphigoid autoantigen 180, is inhibited by dapsone
    • Schmidt E, Reimer S, Kruse N, Broeckner EB, Zillikens D, (2001) The IL-8 release from cultured human keratinocytes, mediated by antibodies to bullous pemphigoid autoantigen 180, is inhibited by dapsone. Clin Exp Immunol 124: 157-162.
    • (2001) Clin Exp Immunol , vol.124 , pp. 157-162
    • Schmidt, E.1    Reimer, S.2    Kruse, N.3    Broeckner, E.B.4    Zillikens, D.5
  • 26
    • 81855185568 scopus 로고    scopus 로고
    • Atypical epidermolysis bullosa simplex with a missense keratin 14 mutation p.Arg125Cys
    • Tsuruta D, Sowa J, Tateishi C, Obase Y, Tsubura A, et al. (2011) Atypical epidermolysis bullosa simplex with a missense keratin 14 mutation p.Arg125Cys. J Dermatol 38: 1177-1179.
    • (2011) J Dermatol , vol.38 , pp. 1177-1179
    • Tsuruta, D.1    Sowa, J.2    Tateishi, C.3    Obase, Y.4    Tsubura, A.5
  • 27
    • 84855994900 scopus 로고    scopus 로고
    • Extensive acantholysis as the major histological feature of a severe case of Dowling-Meara-epidermolysis bullosa simplex: a reappraisal of acantholysis in the newborn
    • Darwich E, Vicente A, Bolling MC, Gonzalez-Ensenat MA, Cusi V, et al. (2011) Extensive acantholysis as the major histological feature of a severe case of Dowling-Meara-epidermolysis bullosa simplex: a reappraisal of acantholysis in the newborn. Eur J Dermatol 21: 966-971.
    • (2011) Eur J Dermatol , vol.21 , pp. 966-971
    • Darwich, E.1    Vicente, A.2    Bolling, M.C.3    Gonzalez-Ensenat, M.A.4    Cusi, V.5
  • 28
    • 0029043889 scopus 로고
    • The basal keratin network of stratified squamous epithelia - defining K15 function in the absence of K14
    • Lloyd C, Yu QC, Cheng JA, Turksen K, Degenstein L, et al. (1995) The basal keratin network of stratified squamous epithelia - defining K15 function in the absence of K14. J Cell Biol 129: 1329-1344.
    • (1995) J Cell Biol , vol.129 , pp. 1329-1344
    • Lloyd, C.1    Yu, Q.C.2    Cheng, J.A.3    Turksen, K.4    Degenstein, L.5
  • 29
    • 78149237578 scopus 로고    scopus 로고
    • K14 mRNA reprogramming for dominant epidermolysis bullosa simplex
    • Wally V, Brunner M, Lettner T, Wagner M, Koller U, et al. (2010) K14 mRNA reprogramming for dominant epidermolysis bullosa simplex. Hum Mol Genet 19: 4715-4725.
    • (2010) Hum Mol Genet , vol.19 , pp. 4715-4725
    • Wally, V.1    Brunner, M.2    Lettner, T.3    Wagner, M.4    Koller, U.5
  • 30
    • 84869143939 scopus 로고    scopus 로고
    • The DSPII splice variant is critical for desmosome-mediated HaCaT keratinocyte adhesion
    • Cabral RM, Tattersall D, Patel V, McPhail GD, Hatzimasoura E, et al. (2012) The DSPII splice variant is critical for desmosome-mediated HaCaT keratinocyte adhesion. J Cell Sci 15: 2853-2861.
    • (2012) J Cell Sci , vol.15 , pp. 2853-2861
    • Cabral, R.M.1    Tattersall, D.2    Patel, V.3    McPhail, G.D.4    Hatzimasoura, E.5
  • 31
    • 3042819618 scopus 로고    scopus 로고
    • Striate palmoplantar keratoderma arising from desmoplakin and desmoglein 1 mutations is associated with contrasting perturbations of desmosomes and the keratin filament network
    • Wan H, Dopping-Hepenstal PJC, Gratian MJ, Stone MG, Zhu G, et al. (2004) Striate palmoplantar keratoderma arising from desmoplakin and desmoglein 1 mutations is associated with contrasting perturbations of desmosomes and the keratin filament network. Br J Dermatol 150: 878-891.
    • (2004) Br J Dermatol , vol.150 , pp. 878-891
    • Wan, H.1    Dopping-Hepenstal, P.J.C.2    Gratian, M.J.3    Stone, M.G.4    Zhu, G.5
  • 32
    • 9444225484 scopus 로고    scopus 로고
    • Mechanical stress induces profound remodelling of keratin filaments and cell junctions in epidermolysis bullosa simplex keratinocytes
    • Russell D, Andrews PD, James J, Lane EB, (2004) Mechanical stress induces profound remodelling of keratin filaments and cell junctions in epidermolysis bullosa simplex keratinocytes. J Cell Sci 117: 5233-5243.
    • (2004) J Cell Sci , vol.117 , pp. 5233-5243
    • Russell, D.1    Andrews, P.D.2    James, J.3    Lane, E.B.4
  • 33
    • 70349453949 scopus 로고    scopus 로고
    • Severe keratin 5 and 14 mutations induce down-regulation of junction proteins in keratinocytes
    • Liovic M, D'Alessandro M, Tomic-Canic M, Bolshakov VN, Coats SE, et al. (2009) Severe keratin 5 and 14 mutations induce down-regulation of junction proteins in keratinocytes. Exp Cell Res 315: 2995-3003.
    • (2009) Exp Cell Res , vol.315 , pp. 2995-3003
    • Liovic, M.1    D'Alessandro, M.2    Tomic-Canic, M.3    Bolshakov, V.N.4    Coats, S.E.5
  • 34
    • 0032841725 scopus 로고    scopus 로고
    • Activation of the small GTPase Cdc42 by the inflammatory cytokines TNFα and IL-1, and by the Epstein-Barr virus transforming protein LMP1
    • Puls A, Eliopoulos AG, Nobes CD, Bridges T, Young LS, et al. (1999) Activation of the small GTPase Cdc42 by the inflammatory cytokines TNFα and IL-1, and by the Epstein-Barr virus transforming protein LMP1. J Cell Sci 112: 2983-2992.
    • (1999) J Cell Sci , vol.112 , pp. 2983-2992
    • Puls, A.1    Eliopoulos, A.G.2    Nobes, C.D.3    Bridges, T.4    Young, L.S.5
  • 35
    • 0028875683 scopus 로고
    • Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 Mitogen-activated protein kinase activation
    • Bagrodia S, Dèrijard B, Davis RJ, Cerione RA, (1995) Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 Mitogen-activated protein kinase activation. J Biol Chem 270: 27995-27998.
    • (1995) J Biol Chem , vol.270 , pp. 27995-27998
    • Bagrodia, S.1    Dèrijard, B.2    Davis, R.J.3    Cerione, R.A.4
  • 36
    • 34547760739 scopus 로고    scopus 로고
    • Activated ezrin promotes cell migration through recruitment of the GEF Dbl to lipid rafts and preferential downstream activation of Cdc42
    • Prag S, Parson M, Keppler MD, Ameer-Beg SM, Barber P, et al. (2007) Activated ezrin promotes cell migration through recruitment of the GEF Dbl to lipid rafts and preferential downstream activation of Cdc42. Mol Biol Cell 18: 2935-2948.
    • (2007) Mol Biol Cell , vol.18 , pp. 2935-2948
    • Prag, S.1    Parson, M.2    Keppler, M.D.3    Ameer-Beg, S.M.4    Barber, P.5
  • 37
    • 0033105764 scopus 로고    scopus 로고
    • Synergistic activation of JNK/SAPK by interleukin-1 and platelet-derived growth factor is independent of Rac and Cdc42
    • Davis W, Stephens LR, Hawkins PT, Saklatvala J, (1999) Synergistic activation of JNK/SAPK by interleukin-1 and platelet-derived growth factor is independent of Rac and Cdc42. Biochem J 338: 387-392.
    • (1999) Biochem J , vol.338 , pp. 387-392
    • Davis, W.1    Stephens, L.R.2    Hawkins, P.T.3    Saklatvala, J.4
  • 38
    • 79960980219 scopus 로고    scopus 로고
    • Interleukin-8 induces the endothelial cell migration through the activation of phosphoinositide 3-kinase-Rac1/RhoA pathway
    • Lai Y, Shen Y, Liu XH, Zhang Y, Zeng Y, et al. (2011) Interleukin-8 induces the endothelial cell migration through the activation of phosphoinositide 3-kinase-Rac1/RhoA pathway. Int J Biol Sci 7: 782-791.
    • (2011) Int J Biol Sci , vol.7 , pp. 782-791
    • Lai, Y.1    Shen, Y.2    Liu, X.H.3    Zhang, Y.4    Zeng, Y.5
  • 39
    • 0035259951 scopus 로고    scopus 로고
    • Role of interleukin-1 in induction of matrix metalloproteinases synthesized by rat temporomandibular joint chondrocytes and disc cells
    • Ijima Y, Koabyashi M, Kubota E, (2001) Role of interleukin-1 in induction of matrix metalloproteinases synthesized by rat temporomandibular joint chondrocytes and disc cells. Eur J Oral Sci 109: 50-59.
    • (2001) Eur J Oral Sci , vol.109 , pp. 50-59
    • Ijima, Y.1    Koabyashi, M.2    Kubota, E.3
  • 40
    • 0345732759 scopus 로고    scopus 로고
    • Cross-talk between RhoGTPases and stress activated kinases for matrix metalloproteinase-9 induction in response to keratinocyte injury
    • Turchi L, Chassot A-A, Bourget I, Baldescchi C, Ortonne JP, et al. (2003) Cross-talk between RhoGTPases and stress activated kinases for matrix metalloproteinase-9 induction in response to keratinocyte injury. J Invest Dermatol 121: 1291-1300.
    • (2003) J Invest Dermatol , vol.121 , pp. 1291-1300
    • Turchi, L.1    Chassot, A.-A.2    Bourget, I.3    Baldescchi, C.4    Ortonne, J.P.5
  • 42
    • 70349566487 scopus 로고    scopus 로고
    • The WASP and WAVE family proteins
    • Kurisu S, Takenawa T, (2009) The WASP and WAVE family proteins. Genome Biol 10: 226.
    • (2009) Genome Biol , vol.10 , pp. 226
    • Kurisu, S.1    Takenawa, T.2
  • 43
    • 0033960791 scopus 로고    scopus 로고
    • How WASP-family proteins and the Arp2/3 complex convert intracellular signals into cytoskeletal structures
    • Mullins RD, (2000) How WASP-family proteins and the Arp2/3 complex convert intracellular signals into cytoskeletal structures. Curr Opin Cell Biol 12: 91-96.
    • (2000) Curr Opin Cell Biol , vol.12 , pp. 91-96
    • Mullins, R.D.1


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