The pathogenetic role of IL-1β in severe epidermolysis Bullosa simplex

Journal of Investigative Dermatology

Volumn 133, Issue 7, 2013, Pages 1901-1903

  Wally, Verena ^a   Lettner, Thomas ^a   Peking, Patricia ^a   Peckl Schmid, Doris ^a   Murauer, Eva M ^a   Hainzl, Stefan ^a   Hintner, Helmut ^a   Bauer, Johann W ^a  

^a PARACELSUS MEDICAL UNIVERSITY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKERATIN 14; INTERLEUKIN 1BETA; MESSENGER RNA; STRESS ACTIVATED PROTEIN KINASE;

CELL ACTIVATION; CELL PROLIFERATION; DISEASE SEVERITY; EPIDERMOLYSIS BULLOSA SIMPLEX; GENE MUTATION; KERATINOCYTE; LETTER; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

EID: 84878106446     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2013.31     Document Type: Letter

References (11)

1. Beriault DR, Haddad O, McCuaig JV et al. (2012) The mechanical behaviour of mutant K14-R125P bundles and networks in NEB-1 keratinocytes. PLoS One 7:e31320
2. Coulombe PA, Kerns ML, Fuchs E (2009) Epidermolysis bullosa simplex: a paradigm for disorders of tissue fragility. J Clin Invest 119:1784-93
3. D'Alessandro M, Russell D, Morley SM et al. (2002) Keratin mutations of epidermolysis bullosa simplex alter the kinetics of stress response to osmotic shock. J Cell Sci 115:4341-51 (Pubitemid 35460704)
4. Freedberg IM, Tomic-Canic M, Komine M et al. (2001) Keratins and the keratinocyte activation cycle. J Invest Dermatol 116:633-40 (Pubitemid 32467639)
5. Jerabkova B, Marek J, Buckova H et al. (2010) Keratin mutations in patients with epidermolysis bullosa simplex: correlations between phenotype severity and disturbance of intermediate filament molecular structure. Br J Dermatol 162:1004-13
6. Liacini A, Sylvester J, Li WQ et al. (2002) Inhibition of interleukin-1-stimulated MAP kinases, activating protein-1(AP-1) and nuclear factor kappa B (NF-kappaB) transcription factors down-regulates matrix metalloproteinase gene expression in articular chondrocytes. Matrix Biol 21:251-62 (Pubitemid 34497016)
7. Moldovan F, Pelletier JP, Jolicoeur FC et al. (2000) Diacerhein and rhein reduce the ICE-induced IL-16 and IL-18 activation in human osteoar-thritic cartilage. Osteoarthritis Cartilage 8: 186-96 (Pubitemid 30304186)
8. Morley SM, D'Alessandro M, Sexton C et al. (2003) Generation and characterization of epidermolysis bullosa simplex cell lines: scratch assays show faster migration with disruptive keratin mutations. Br J Dermatol 149:46-58 (Pubitemid 36966510)
9. Stephens K, Sybert VP, Wijsman EM et al. (1993) A keratin-14 mutational hot-spot for epidermolysis-bullosa simplex, Dowling-Meara-implications for diagnosis. J Invest Dermatol 101:240-3
10. Verbruggen G (2000) Chondroprotective drugs in degenerative joint diseases. Rheumatology 45:129-38
11. Wally V, Brunner M, Lettner T et al. (2010) K14 mRNA reprogramming for dominant epidermolysis bullosa simplex. Hum Mol Genet 19:4715-25