Knockout of 5-lipoxygenase prevents dexamethasone-induced tau pathology in 3xTg mice

Aging Cell

Volumn 12, Issue 4, 2013, Pages 706-711

  Joshi, Yash B ^a   Chu, Jin ^a   Praticò, Domenico ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

5 lipoxygenase; Alzheimer's disease; Amyloid; Glucocorticoid; Tau protein; Transgenic mouse models

Indexed keywords

AMYLOID BETA PROTEIN; ANTIBODY; ARACHIDONATE 5 LIPOXYGENASE; DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; GLYCOGEN SYNTHASE KINASE 3BETA; POSTSYNAPTIC DENSITY PROTEIN 95; SYNAPTOPHYSIN; TAU PROTEIN; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; LIPOXYGENASE INHIBITOR; MAPT PROTEIN, MOUSE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; MEMORY; METABOLISM; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RISK FACTOR; TAUOPATHY; TRANSGENIC MOUSE; ANIMAL; ANIMAL BEHAVIOR; BRAIN; COGNITION; DISEASE MODEL; DRUG EFFECTS; ENZYME ACTIVATION; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; MAZE TEST; MENTAL STRESS; PATHOLOGY; PHOSPHORYLATION; SOLUBILITY;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; ARACHIDONATE 5-LIPOXYGENASE; BEHAVIOR, ANIMAL; BRAIN; COGNITION; DEXAMETHASONE; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLYCOGEN SYNTHASE KINASE 3; LIPOXYGENASE INHIBITORS; MAZE LEARNING; MEMORY; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PHOSPHORYLATION; SOLUBILITY; STRESS, PSYCHOLOGICAL; TAU PROTEINS;

EID: 84880447240     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12096     Document Type: Article

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