-
1
-
-
79952232216
-
Global cancer statistics, 2002
-
Jemal A, Bray F, Center M M, Ferlay J, Ward E, Forman D. Global cancer statistics, 2002. CA Cancer J.Clin. 61(2), 69-90. (2011)
-
(2011)
CA Cancer J.Clin
, vol.61
, Issue.2
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
2
-
-
84855792427
-
Cancer statistics, 2012
-
Siegel R, Naishadham D, Jemal A. Cancer statistics, 2012. CA Cancer J.Clin 62, 10-29. (2012)
-
(2012)
CA Cancer J.Clin
, vol.62
, pp. 10-29
-
-
Siegel, R.1
Naishadham, D.2
Jemal, A.3
-
3
-
-
0026011979
-
Implications of peritoneal cytology for staging of early pancreatic cancer
-
Warshaw AL. Implications of peritoneal cytology for staging of early pancreatic cancer. Am I Surg 161(1), 26-9. (1991)
-
(1991)
Am i Surg
, vol.161
, Issue.1
, pp. 26-29
-
-
Warshaw, A.L.1
-
4
-
-
1642588228
-
Pancreatic cancer
-
DOI 10.1016/S0140-6736(04)15841-8, PII S0140673604158418
-
Li D, Xie K, Wolff R, Abbruzzese JL. Pancreatic cancer. Lancet 363(9414), 1049-1057. (2004) (Pubitemid 38410779)
-
(2004)
Lancet
, vol.363
, Issue.9414
, pp. 1049-1057
-
-
Li, D.1
Xie, K.2
Wolff, R.3
Abbruzzese, J.L.4
-
5
-
-
26944473246
-
Annual report to the nation on the status of cancer, 1975-2002, featuring population-based trends in cancer treatment
-
DOI 10.1093/jnci/dji289
-
Edwards BK, Brown ML, Wingo PA, Howe HL, Ward E, Ries LA, Schrag D, Jamison PM, Jemal A, Wu XC, Friedman C, Harlan L, Warren J, Anderson RN, Pickle LW. Annual report to the nation on the status of cancer, 1975-2002, featuring population-based trends in cancer treatment. J Natl Cancer Inst 97(19), (1407-1427). (2005) (Pubitemid 41520077)
-
(2005)
Journal of the National Cancer Institute
, vol.97
, Issue.19
, pp. 1407-1427
-
-
Edwards, B.K.1
Brown, M.L.2
Wingo, P.A.3
Howe, H.L.4
Ward, E.5
Ries, L.A.G.6
Schrag, D.7
Jamison, P.M.8
Jemal, A.9
Wu, X.C.10
Friedman, C.11
Harlan, L.12
Warren, J.13
Anderson, R.N.14
Pickle, L.W.15
-
7
-
-
70349406578
-
Pancreatic cancer stem cells - Insights and perspectives
-
Hermann PC, Mueller MT, Heeschen C. Pancreatic cancer stem cells - insights and perspectives. Expert Opin Biol Ther 9(10), 1271-8. (2009)
-
(2009)
Expert Opin Biol Ther
, vol.9
, Issue.10
, pp. 1271-1318
-
-
Hermann, P.C.1
Mueller, M.T.2
Heeschen, C.3
-
8
-
-
72549089933
-
Pancreatic cancer stem cells: New understanding of tumorigenesis, clinical implications
-
Ischenko I, Seeliger H, Kleespies A, Angele MK, Eichhorn ME, Jauch KW, Bruns CJ. Pancreatic cancer stem cells: new understanding of tumorigenesis, clinical implications. Langenbecks Arch Surg 395(1), 1-10. (2009)
-
(2009)
Langenbecks Arch Surg
, vol.395
, Issue.1
, pp. 1-10
-
-
Ischenko, I.1
Seeliger, H.2
Kleespies, A.3
Angele, M.K.4
Eichhorn, M.E.5
Jauch, K.W.6
Bruns, C.J.7
-
9
-
-
75849125982
-
Breast cancer chemoresistance: Emerging importance of cancer stem cells
-
Chuthapisith S, Eremin J, El-Sheemey M, Eremin O. Breast cancer chemoresistance: emerging importance of cancer stem cells. Surg Oncol 19(1), 27-32. (2010)
-
(2010)
Surg Oncol
, vol.19
, Issue.1
, pp. 27-32
-
-
Chuthapisith, S.1
Eremin, J.2
El-Sheemey, M.3
Eremin, O.4
-
10
-
-
84874400094
-
The role of head and neck squamous cell carcinoma cancer stem cells in tumorigenesis, metastasis, and treatment failure
-
Chinn SB, Darr OA, Peters RD, Prince ME. The role of head and neck squamous cell carcinoma cancer stem cells in tumorigenesis, metastasis, and treatment failure. Front Endocrinol (Lausanne) 3, 90. (2012)
-
(2012)
Front Endocrinol (Lausanne)
, vol.3
, pp. 90
-
-
Chinn, S.B.1
Darr, O.A.2
Peters, R.D.3
Prince, M.E.4
-
11
-
-
33847419143
-
Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice
-
DOI 10.1016/j.ccr.2007.01.012, PII S153561080700027X
-
Guerra C, Schuhmacher AJ, Canamero M, Grippo PJ, Verdaguer L, Perez-Gallego L, Dubus P, Sandgren EP, Barbacid M. Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice. Cancer Cell 11(3), 291-302. (2007) (Pubitemid 46349841)
-
(2007)
Cancer Cell
, vol.11
, Issue.3
, pp. 291-302
-
-
Guerra, C.1
Schuhmacher, A.J.2
Canamero, M.3
Grippo, P.J.4
Verdaguer, L.5
Perez-Gallego, L.6
Dubus, P.7
Sandgren, E.P.8
Barbacid, M.9
-
12
-
-
34547667454
-
Acinar cells contribute to the molecular heterogeneity of pancreatic intraepithelial neoplasia
-
DOI 10.2353/ajpath.2007.061176
-
Zhu L, Shi G, Schmidt CM, Hruban RH, Konieczny SF. Acinar cells contribute to the molecular heterogeneity of pancreatic intraepithelial neoplasia. Am J Pathol 171(1), 263-73. (2007) (Pubitemid 47339243)
-
(2007)
American Journal of Pathology
, vol.171
, Issue.1
, pp. 263-273
-
-
Zhu, L.1
Shi, G.2
Schmidt, C.M.3
Hruban, R.H.4
Konieczny, S.F.5
-
13
-
-
31544467540
-
Pathology of genetically engineered mouse models of pancreatic exocrine cancer: Consensus report and recommendations
-
DOI 10.1158/0008-5472.CAN-05-2168
-
Hruban RH, Adsay NV, Albores-Saavedra J, Anver MR, Biankin AV, Boivin GP, Furth EE, Furukawa T, Klein A, Klimstra DS, Kloppel G, Lauwers GY, Longnecker DS, Luttges J, Maitra A, Offerhaus GJ, Perez-Gallego L, Redston M, Tuveson DA. Pathology of genetically engineered mouse models of pancreatic exocrine cancer: consensus report and recommendations. Cancer Res 66(1), 95-106. (2006) (Pubitemid 43166014)
-
(2006)
Cancer Research
, vol.66
, Issue.1
, pp. 95-106
-
-
Hruban, R.H.1
Adsay, N.V.2
Albores-Saavedra, J.3
Anver, M.R.4
Biankin, A.V.5
Boivin, G.P.6
Furth, E.E.7
Furukawa, T.8
Klein, A.9
Klimstra, D.S.10
Kloppel, G.11
Lauwers, G.Y.12
Longnecker, D.S.13
Luttges, J.14
Maitra, A.15
Offerhaus, G.J.A.16
Perez-Gallego, L.17
Redston, M.18
Tuveson, D.A.19
-
14
-
-
33847020899
-
Isolation of Mouse Pancreatic Ductal Progenitor Cells Expressing CD133 and c-Met by Flow Cytometric Cell Sorting
-
DOI 10.1053/j.gastro.2006.11.027, PII S0016508506024826
-
Oshima Y, Suzuki A, Kawashimo K, Ishikawa M, Ohkohchi N, Taniguchi H. Isolation of mouse pancreatic ductal progenitor cells expressing CD133 and c-Met by fl ow cytometric cell sorting. Gastroenterology 132(2), 720-32. (2007) (Pubitemid 46274661)
-
(2007)
Gastroenterology
, vol.132
, Issue.2
, pp. 720-732
-
-
Oshima, Y.1
Suzuki, A.2
Kawashimo, K.3
Ishikawa, M.4
Ohkohchi, N.5
Taniguchi, H.6
-
15
-
-
33847052127
-
Identification of pancreatic cancer stem cells
-
Li C, Heidt DG, Dalerba P, Burant CF, Zhang L, Adsay V, Wicha M, Clarke MF, Simeone DM. Identification of pancreatic cancer stem cells. Cancer Res 67(3), 1030-7. (2007)
-
(2007)
Cancer Res
, vol.67
, Issue.3
, pp. 1030-1117
-
-
Li, C.1
Heidt, D.G.2
Dalerba, P.3
Burant, C.F.4
Zhang, L.5
Adsay, V.6
Wicha, M.7
Clarke, M.F.8
Simeone, D.M.9
-
16
-
-
34548455927
-
Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
-
DOI 10.1016/j.stem.2007.06.002, PII S1934590907000665
-
Hermann PC, Huber SL, Herrler T, Aicher A, Ellwart JW, Guba M, Bruns CJ, Heeschen C. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 1(3), 313-23. (2007) (Pubitemid 47355323)
-
(2007)
Cell Stem Cell
, vol.1
, Issue.3
, pp. 313-323
-
-
Hermann, P.C.1
Huber, S.L.2
Herrler, T.3
Aicher, A.4
Ellwart, J.W.5
Guba, M.6
Bruns, C.J.7
Heeschen, C.8
-
17
-
-
77954921889
-
Enhanced cell migration and invasion of CD133+ pancreatic cancer cells cocultured with pancreatic stromal cells
-
Moriyama T, Ohuchida K, Mizumoto K, Cui L, Ikenaga N, Sato N, Tanaka M. Enhanced cell migration and invasion of CD133+ pancreatic cancer cells cocultured with pancreatic stromal cells. Cancer 116(14), 3357-68. (2010)
-
(2010)
Cancer
, vol.116
, Issue.14
, pp. 3357-3368
-
-
Moriyama, T.1
Ohuchida, K.2
Mizumoto, K.3
Cui, L.4
Ikenaga, N.5
Sato, N.6
Tanaka, M.7
-
18
-
-
84858184063
-
Establishment of a highly migratory subclone reveals that CD133 contributes to migration and invasion through epithelialmesenchymal transition in pancreatic cancer
-
Ding Q, Yoshimitsu M, Kuwahata T, Maeda K, Hayashi T, Obara T, Miyazaki Y, Matsubara S, Natsugoe S, Takao S. Establishment of a highly migratory subclone reveals that CD133 contributes to migration and invasion through epithelialmesenchymal transition in pancreatic cancer. Hum Cell 25(1), 1-8. (2012)
-
(2012)
Hum Cell
, vol.25
, Issue.1
, pp. 1-8
-
-
Ding, Q.1
Yoshimitsu, M.2
Kuwahata, T.3
Maeda, K.4
Hayashi, T.5
Obara, T.6
Miyazaki, Y.7
Matsubara, S.8
Natsugoe, S.9
Takao, S.10
-
19
-
-
81055136620
-
Significance of CD133 as a cancer stem cell markers focusing on the tumorigenicity of pancreatic cancer cell lines
-
Lee HJ, You DD, Choi DW, Choi YS, Kim SJ, Won YS, Moon HJ. Significance of CD133 as a cancer stem cell markers focusing on the tumorigenicity of pancreatic cancer cell lines. J Korean Surg Soc 81(4), 263-70. (2011)
-
(2011)
J Korean Surg Soc
, vol.81
, Issue.4
, pp. 263-270
-
-
Lee, H.J.1
You, D.D.2
Choi, D.W.3
Choi, Y.S.4
Kim, S.J.5
Won, Y.S.6
Moon, H.J.7
-
20
-
-
34548455927
-
Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
-
DOI 10.1016/j.stem.2007.06.002, PII S1934590907000665
-
Hermann PC, Huber SL, Herrler T, Aicher A, Ellwart JW, Guba M, Bruns CJ, Heeschen C. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 1(3), 313-23. (2007) (Pubitemid 47355323)
-
(2007)
Cell Stem Cell
, vol.1
, Issue.3
, pp. 313-323
-
-
Hermann, P.C.1
Huber, S.L.2
Herrler, T.3
Aicher, A.4
Ellwart, J.W.5
Guba, M.6
Bruns, C.J.7
Heeschen, C.8
-
21
-
-
54349112926
-
The chemokine receptor CXCR4 is expressed in pancreatic intraepithelial neoplasia
-
Thomas RM, Kim J, Revelo-Penafiel MP, Angel R, Dawson DW, Lowy AM. The chemokine receptor CXCR4 is expressed in pancreatic intraepithelial neoplasia. Gut 57(11), 1555-60. (2008)
-
(2008)
Gut
, vol.57
, Issue.11
, pp. 1555-1560
-
-
Thomas, R.M.1
Kim, J.2
Revelo-Penafiel, M.P.3
Angel, R.4
Dawson, D.W.5
Lowy, A.M.6
-
22
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell 136 (2), 215-233. (2009)
-
(2009)
Cell
, vol.136
, Issue.2
, pp. 215-233
-
-
Bartel, D.P.1
-
23
-
-
41149098674
-
MicroRNA biogenesis, functionality and cancer relevance
-
Kusenda B, Mraz M, Mayer J, Pospisilova S. MicroRNA biogenesis, functionality and cancer relevance. Biomedical papers 150 (2), 205-215. (2006)
-
(2006)
Biomedical Papers
, vol.150
, Issue.2
, pp. 205-215
-
-
Kusenda, B.1
Mraz, M.2
Mayer, J.3
Pospisilova, S.4
-
24
-
-
69949087531
-
MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells
-
Ji Q, Hao X, Zhang M, Tang W, Yang M, Li L, Xiang D, Desano JT, Bommer GT, Fan D, Fearon ER, Lawrence TS, Xu L. MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells. PLoS One 4(8), e6816. (2009)
-
(2009)
PLoS One
, vol.4
, Issue.8
-
-
Ji, Q.1
Hao, X.2
Zhang, M.3
Tang, W.4
Yang, M.5
Li, L.6
Xiang, D.7
Desano, J.T.8
Bommer, G.T.9
Fan, D.10
Fearon, E.R.11
Lawrence, T.S.12
Xu, L.13
-
25
-
-
80054855853
-
Differentially expressed microRNAs in pancreatic cancer stem cells
-
Jung DE, Wen J, Oh T, Song SY. Differentially expressed microRNAs in pancreatic cancer stem cells. Pancreas 40(8), 1180-7. (2011)
-
(2011)
Pancreas
, vol.40
, Issue.8
, pp. 1180-1217
-
-
Jung, D.E.1
Wen, J.2
Oh, T.3
Song, S.Y.4
-
26
-
-
80555145216
-
Hedgehog signaling antagonist GDC-0449 (Vismodegib) inhibits pancreatic cancer stem cell characteristics: Molecular mechanisms
-
Singh BN, Fu J, Srivastava RK, Shankar S. Hedgehog signaling antagonist GDC-0449 (Vismodegib) inhibits pancreatic cancer stem cell characteristics: molecular mechanisms. PLoS One 6(11), e27306. (2011)
-
(2011)
PLoS One
, vol.6
, Issue.11
-
-
Singh, B.N.1
Fu, J.2
Srivastava, R.K.3
Shankar, S.4
-
27
-
-
1042298768
-
Regulation of Hedgehog signaling: A complex story
-
DOI 10.1016/j.bcp.2004.01.002
-
Ogden SK, Ascano M Jr., Stegman MA, Robbins DJ. Regulation of Hedgehog signaling: a complex story. Biochem Pharmacol 67(5), 805-14. (2004) (Pubitemid 38201626)
-
(2004)
Biochemical Pharmacology
, vol.67
, Issue.5
, pp. 805-814
-
-
Ogden, S.K.1
Ascano Jr., M.2
Stegman, M.A.3
Robbins, D.J.4
-
28
-
-
84860214416
-
Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics
-
Tang SN, Fu J, Nall D, Rodova M, Shankar S, Srivastava RK. Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics. Int J Cancer 131(1), 30-40. (2012)
-
(2012)
Int J Cancer
, vol.131
, Issue.1
, pp. 30-40
-
-
Tang, S.N.1
Fu, J.2
Nall, D.3
Rodova, M.4
Shankar, S.5
Srivastava, R.K.6
-
29
-
-
52949086129
-
Therapeutic inhibition of Hedgehog- GLI signaling in cancer: Epithelial, stromal, or stem cell targets?
-
Ruiz i Altaba A. Therapeutic inhibition of Hedgehog- GLI signaling in cancer: epithelial, stromal, or stem cell targets? Cancer Cell 14(4), 281-3.(2008)
-
(2008)
Cancer Cell
, vol.14
, Issue.4
, pp. 281-323
-
-
Ruiz, I.1
Altaba, A.2
-
30
-
-
70949096151
-
The hedgehog pathway and pancreatic cancer
-
Hidalgo M, Maitra A. The hedgehog pathway and pancreatic cancer. N Engl J Med 361(21), 2094-2096. (2009)
-
(2009)
N Engl J Med
, vol.361
, Issue.21
, pp. 2094-2096
-
-
Hidalgo, M.1
Maitra, A.2
-
31
-
-
84860431671
-
Pancreatic stellate cells enhance stem cell-like phenotypes in pancreatic cancer cells
-
Hamada S, Masamune A, Takikawa T, Suzuki N, Kikuta K, Hirota M, Hamada H, Kobune M, Satoh K, Shimosegawa T. Pancreatic stellate cells enhance stem cell-like phenotypes in pancreatic cancer cells. Biochem Biophys Res Commun 421(2), 349-54. (2012)
-
(2012)
Biochem Biophys Res Commun
, vol.421
, Issue.2
, pp. 349-354
-
-
Hamada, S.1
Masamune, A.2
Takikawa, T.3
Suzuki, N.4
Kikuta, K.5
Hirota, M.6
Hamada, H.7
Kobune, M.8
Satoh, K.9
Shimosegawa, T.10
-
32
-
-
79953147370
-
A perspective on cancer cell metastasis
-
Chaffer CL, Weinberg RA. A perspective on cancer cell metastasis. Science 331(6024), 1559-64. (2011)
-
(2011)
Science
, vol.331
, Issue.6024
, pp. 1559-1564
-
-
Chaffer, C.L.1
Weinberg, R.A.2
-
33
-
-
65649095142
-
Side population of pancreatic cancer cells predominates in TGF-beta-mediated epithelial to mesenchymal transition and invasion
-
Kabashima A, Higuchi H, Takaishi H, Matsuzaki Y, Suzuki S, Izumiya M, Iizuka H, Sakai G, Hozawa S, Azuma T, Hibi T. Side population of pancreatic cancer cells predominates in TGF-beta-mediated epithelial to mesenchymal transition and invasion. Int J Cancer 124(12), 2771-9. (2009)
-
(2009)
Int J Cancer
, vol.124
, Issue.12
, pp. 2771-2829
-
-
Kabashima, A.1
Higuchi, H.2
Takaishi, H.3
Matsuzaki, Y.4
Suzuki, S.5
Izumiya, M.6
Iizuka, H.7
Sakai, G.8
Hozawa, S.9
Azuma, T.10
Hibi, T.11
-
34
-
-
78650248243
-
Inhibition of Notch signaling reduces the stem-like population of breast cancer cells and prevents mammosphere formation
-
Grudzien P, Lo S, Albain KS, Robinson P, Rajan P, Strack PR, Golde TE, Miele L, Foreman KE. Inhibition of Notch signaling reduces the stem-like population of breast cancer cells and prevents mammosphere formation. Anticancer Res 30(10), 3853-67. (2010)
-
(2010)
Anticancer Res
, vol.30
, Issue.10
, pp. 3853-3867
-
-
Grudzien, P.1
Lo, S.2
Albain, K.S.3
Robinson, P.4
Rajan, P.5
Strack, P.R.6
Golde, T.E.7
Miele, L.8
Foreman, K.E.9
-
35
-
-
77249117415
-
Pancreatic cancer stem cells and EMT in drug resistance and metastasis
-
Sarkar FH, Li Y, Wang Z, Kong D. Pancreatic cancer stem cells and EMT in drug resistance and metastasis. Minerva Chir 64(5), 489-500. (2009)
-
(2009)
Minerva Chir
, vol.64
, Issue.5
, pp. 489-500
-
-
Sarkar, F.H.1
Li, Y.2
Wang, Z.3
Kong, D.4
-
36
-
-
77956178360
-
EMT, cancer stem cells and drug resistance: An emerging axis of evil in the war on cancer
-
Singh A, Settleman J. EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer. Oncogene 29(34), 4741-51. (2010)
-
(2010)
Oncogene
, vol.29
, Issue.34
, pp. 4741-4751
-
-
Singh, A.1
Settleman, J.2
-
37
-
-
77953523118
-
The role of Notch signaling pathway in epithelialmesenchymal transition (EMT) during development and tumor aggressiveness
-
Wang Z, Li Y, Kong D, Sarkar FH. The role of Notch signaling pathway in epithelialmesenchymal transition (EMT) during development and tumor aggressiveness. Curr Drug Targets 11(6), 745-51. (2010)
-
(2010)
Curr Drug Targets
, vol.11
, Issue.6
, pp. 745-751
-
-
Wang, Z.1
Li, Y.2
Kong, D.3
Sarkar, F.H.4
-
38
-
-
79957487931
-
Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells
-
Bao B, Wang Z, Ali S, Kong D, Li Y, Ahmad A, Banerjee S, Azmi AS, Miele L, Sarkar FH. Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells. Cancer Lett 307(1), 26-36. (2011)
-
(2011)
Cancer Lett
, vol.307
, Issue.1
, pp. 26-36
-
-
Bao, B.1
Wang, Z.2
Ali, S.3
Kong, D.4
Li, Y.5
Ahmad, A.6
Banerjee, S.7
Azmi, A.S.8
Miele, L.9
Sarkar, F.H.10
-
39
-
-
84860390076
-
Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells
-
Bao B, Wang Z, Ali S, Kong D, Banerjee S, Ahmad A, Li Y, Azmi AS, Miele L, Sarkar FH. Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells. J Cell Biochem 112(9), 2296-306. (2011)
-
(2011)
J Cell Biochem
, vol.112
, Issue.9
, pp. 2296-2306
-
-
Bao, B.1
Wang, Z.2
Ali, S.3
Kong, D.4
Banerjee, S.5
Ahmad, A.6
Li, Y.7
Azmi, A.S.8
Miele, L.9
Sarkar, F.H.10
-
40
-
-
84878924826
-
Activated K-Ras and INK4a/Arf deficiency promote aggressiveness of pancreatic cancer by induction of EMT consistent with cancer stem cell phenotype
-
(Epub ahead of print)
-
Wang Z, Ali S, Banerjee S, Bao B, Li Y, Azmi AS, Korc M, Sarkar FH. Activated K-Ras and INK4a/Arf deficiency promote aggressiveness of pancreatic cancer by induction of EMT consistent with cancer stem cell phenotype. J Cell Physiol (Epub ahead of print). (2012)
-
(2012)
J Cell Physiol
-
-
Wang, Z.1
Ali, S.2
Banerjee, S.3
Bao, B.4
Li, Y.5
Azmi, A.S.6
Korc, M.7
Sarkar, F.H.8
-
41
-
-
16844368698
-
Tumour stem cells and drug resistance
-
DOI 10.1038/nrc1590
-
Dean M, Fojo T, Bates S. Tumour stem cells and drug resistance. Nat Rev Cancer 5(4). 275-84. (2005) (Pubitemid 40488633)
-
(2005)
Nature Reviews Cancer
, vol.5
, Issue.4
, pp. 275-284
-
-
Dean, M.1
Fojo, T.2
Bates, S.3
-
42
-
-
79959568293
-
Alpha-fetoprotein-producing pancreatic cancer cells possess cancer stem cell characteristics
-
Sasaki N, Ishii T, Kamimura R, Kajiwara M, Machimoto T, Nakatsuji N, Suemori H, Ikai I, Yasuchika K, Uemoto S. Alpha-fetoprotein-producing pancreatic cancer cells possess cancer stem cell characteristics. Cancer Lett 308(2), 152-61. (2011)
-
(2011)
Cancer Lett
, vol.308
, Issue.2
, pp. 152-161
-
-
Sasaki, N.1
Ishii, T.2
Kamimura, R.3
Kajiwara, M.4
Machimoto, T.5
Nakatsuji, N.6
Suemori, H.7
Ikai, I.8
Yasuchika, K.9
Uemoto, S.10
-
43
-
-
84871518452
-
Altered expressions of embryonic stem-related genes in pancreatic cancer stem cell
-
Lu YH, Zhu H, Wang ZW, Fan XJ, Zhu SJ, Li XH, Wang Y, Lu JJ, Zhu MY. Altered expressions of embryonic stem-related genes in pancreatic cancer stem cell. Zhonghua Yi Xue Za Zhi 91(44), 3107-10. (2011)
-
(2011)
Zhonghua Yi Xue Za Zhi
, vol.91
, Issue.44
, pp. 3107-3110
-
-
Lu, Y.H.1
Zhu, H.2
Wang, Z.W.3
Fan, X.J.4
Zhu, S.J.5
Li, X.H.6
Wang, Y.7
Lu, J.J.8
Zhu, M.Y.9
-
44
-
-
77953798273
-
Synergistic activity of sorafenib and sulforaphane abolishes pancreatic cancer stem cell characteristics
-
Rausch V, Liu L, Kallifatidis G, Baumann B, Mattern J, Gladkich J, Wirth T, Schemmer P, Büchler MW, Zöller M, Salnikov AV, Herr I. Synergistic activity of sorafenib and sulforaphane abolishes pancreatic cancer stem cell characteristics. Cancer Res 70(12), 5004-13. (2010)
-
(2010)
Cancer Res
, vol.70
, Issue.12
, pp. 5004-5013
-
-
Rausch, V.1
Liu, L.2
Kallifatidis, G.3
Baumann, B.4
Mattern, J.5
Gladkich, J.6
Wirth, T.7
Schemmer, P.8
Büchler, M.W.9
Zöller, M.10
Salnikov, A.V.11
Herr, I.12
-
45
-
-
79551617718
-
Resveratrol inhibits pancreatic cancer stem cell characteristics in human and KrasG12D transgenic mice by inhibiting pluripotency maintaining factors and epithelial-mesenchymal transition
-
Shankar S, Nall D, Tang SN, Meeker D, Passarini J, Sharma J, Srivastava RK. Resveratrol inhibits pancreatic cancer stem cell characteristics in human and KrasG12D transgenic mice by inhibiting pluripotency maintaining factors and epithelial-mesenchymal transition. PLoS One 6(1), e16530. (2011)
-
(2011)
PLoS One
, vol.6
, Issue.1
-
-
Shankar, S.1
Nall, D.2
Tang, S.N.3
Meeker, D.4
Passarini, J.5
Sharma, J.6
Srivastava, R.K.7
-
46
-
-
79957794952
-
Sulforaphane synergizes with quercetin to inhibit selfrenewal capacity of pancreatic cancer stem cells
-
(Elite Ed)
-
Srivastava RK, Tang SN, Zhu W, Meeker D, Shankar S. Sulforaphane synergizes with quercetin to inhibit selfrenewal capacity of pancreatic cancer stem cells. Front Biosci (Elite Ed) 3, 515-28. (2011)
-
(2011)
Front Biosci
, vol.3
, pp. 515-528
-
-
Srivastava, R.K.1
Tang, S.N.2
Zhu, W.3
Meeker, D.4
Shankar, S.5
-
47
-
-
82155163849
-
The homeobox gene MSX2 determines chemosensitivity of pancreatic cancer cells via the regulation of transporter gene ABCG2
-
Hamada S, Satoh K, Hirota M, Kanno A, Umino J, Ito H, Masamune A, Kikuta K, Kume K, Shimosegawa T. The homeobox gene MSX2 determines chemosensitivity of pancreatic cancer cells via the regulation of transporter gene ABCG2. J Cell Physiol 227(2), 729-38. (2012)
-
(2012)
J Cell Physiol
, vol.227
, Issue.2
, pp. 729-738
-
-
Hamada, S.1
Satoh, K.2
Hirota, M.3
Kanno, A.4
Umino, J.5
Ito, H.6
Masamune, A.7
Kikuta, K.8
Kume, K.9
Shimosegawa, T.10
-
48
-
-
77956543290
-
Dietary polyphenol quercetin targets pancreatic cancer stem cells
-
Zhou W, Kallifatidis G, Baumann B, Rausch V, Mattern J, Gladkich J, Giese N, Moldenhauer G, Wirth T, Büchler MW, Salnikov AV, Herr I. Dietary polyphenol quercetin targets pancreatic cancer stem cells. Int J Oncol 37(3), 551-61. (2010)
-
(2010)
Int J Oncol
, vol.37
, Issue.3
, pp. 551-561
-
-
Zhou, W.1
Kallifatidis, G.2
Baumann, B.3
Rausch, V.4
Mattern, J.5
Gladkich, J.6
Giese, N.7
Moldenhauer, G.8
Wirth, T.9
Büchler, M.W.10
Salnikov, A.V.11
Herr, I.12
-
49
-
-
84860214416
-
Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics
-
Tang SN, Fu J, Nall D, Rodova M, Shankar S, Srivastava RK. Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics. Int J Cancer 131(1). 30-40. (2012)
-
(2012)
Int J Cancer
, vol.131
, Issue.1
, pp. 30-40
-
-
Tang, S.N.1
Fu, J.2
Nall, D.3
Rodova, M.4
Shankar, S.5
Srivastava, R.K.6
-
50
-
-
8244254377
-
Improvements in survival and clinical benefit with gemcitabine as first- line therapy for patients with advanced pancreas cancer: A randomized trial
-
Burris HA 3rd, Moore MJ, Andersen J, Green MR, Rothenberg ML, Modiano MR, Cripps MC, Portenoy RK, Storniolo AM, Tarassoff P, Nelson R, Dorr FA, Stephens CD, Von Hoff DD. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol 15(6), 2403-13. (1997) (Pubitemid 27251144)
-
(1997)
Journal of Clinical Oncology
, vol.15
, Issue.6
, pp. 2403-2413
-
-
Burris III, H.A.1
Moore, M.J.2
Andersen, J.3
Green, M.R.4
Rothenberg, M.L.5
Modiano, M.R.6
Cripps, M.C.7
Portenoy, R.K.8
Storniolo, A.M.9
Tarassoff, P.10
Nelson, R.11
Dorr, F.A.12
Stephens, C.D.13
Von Hoff, D.D.14
-
51
-
-
0030049697
-
Phase II study of gemcitabine in patients with advanced pancreatic cancer
-
Carmichael J, Fink U, Russell RC, Spittle MF, Harris AL, Spiessi G, Blatter J. Phase II study of gemcitabine in patients with advanced pancreatic cancer. Br J Cancer 73(1), 101-5. (1996) (Pubitemid 26026268)
-
(1996)
British Journal of Cancer
, vol.73
, Issue.1
, pp. 101-105
-
-
Carmichael, J.1
Fink, U.2
Russell, R.C.G.3
Spittle, M.F.4
Harris, A.L.5
Spiessi, G.6
Blatter, J.7
-
52
-
-
10744221950
-
Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1beta
-
Müerköster S, Wegehenkel K, Arlt A, Witt M, Sipos B, Kruse ML, Sebens T, Klöppel G, Kalthoff H, Fölsch UR, Schäfer H. Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1beta. Cancer Res 64(4), 1331-7. (2004)
-
(2004)
Cancer Res
, vol.64
, Issue.4
, pp. 1331-1417
-
-
Müerköster, S.1
Wegehenkel, K.2
Arlt, A.3
Witt, M.4
Sipos, B.5
Kruse, M.L.6
Sebens, T.7
Klöppel, G.8
Kalthoff, H.9
Fölsch, U.R.10
Schäfer, H.11
-
53
-
-
0037130286
-
Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase
-
DOI 10.1016/S0925-4439(02)00079-0, PII S0925443902000790
-
Banerjee D, Mayer-Kuckuk P, Capiaux G, Budak- Alpdogan T, Gorlick R, Bertino Jr. Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase. Biochim Biophys Acta. 1587(2-3), 164-73. (2002) (Pubitemid 34657277)
-
(2002)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1587
, Issue.2-3
, pp. 164-173
-
-
Banerjee, D.1
Mayer-Kuckuk, P.2
Capiaux, G.3
Budak-Alpdogan, T.4
Gorlick, R.5
Bertino, J.R.6
-
54
-
-
79955647790
-
Establish a gemcitabine-resistant pancreatic cancer cell line SW1990/GZ and research the relationship between SW1990/GZ and pancreatic cancer stem cell
-
An Y, Yao J, Wei JS, Lu ZP, Cai HH, Dai CC, Qian ZY, Xu ZK, Miao Y. Establish a gemcitabine-resistant pancreatic cancer cell line SW1990/GZ and research the relationship between SW1990/GZ and pancreatic cancer stem cell. Zhonghua Wai Ke Za Zhi 48(13), 999-1003. (2010)
-
(2010)
Zhonghua Wai Ke Za Zhi
, vol.48
, Issue.13
, pp. 999-1003
-
-
An, Y.1
Yao, J.2
Wei, J.S.3
Lu, Z.P.4
Cai, H.H.5
Dai, C.C.6
Qian, Z.Y.7
Xu, Z.K.8
Miao, Y.9
-
55
-
-
84863116036
-
Intrinsic gemcitabine resistance in a novel pancreatic cancer cell line is associated with cancer stem cell-like phenotype
-
Hu G, Li F, Ouyang K, Xie F, Tang X, Wang K, Han S, Jiang Z, Zhu M, Wen D, Qin X, Zhang L. Intrinsic gemcitabine resistance in a novel pancreatic cancer cell line is associated with cancer stem cell-like phenotype. Int J Oncol 40(3), 798-806. (2012)
-
(2012)
Int J Oncol
, vol.40
, Issue.3
, pp. 798-806
-
-
Hu, G.1
Li, F.2
Ouyang, K.3
Xie, F.4
Tang, X.5
Wang, K.6
Han, S.7
Jiang, Z.8
Zhu, M.9
Wen, D.10
Qin, X.11
Zhang, L.12
-
56
-
-
0242270878
-
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
-
DOI 10.1038/nature02009
-
Thayer SP, di Magliano MP, Heiser PW, Nielsen CM, Roberts DJ, Lauwers GY, Qi YP, Gysin S, Fernández-del Castillo C, Yajnik V, Antoniu B, McMahon M, Warshaw AL, Hebrok M. Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature 425(6960), 851-6. (2003) (Pubitemid 37355945)
-
(2003)
Nature
, vol.425
, Issue.6960
, pp. 851-856
-
-
Thayer, S.P.1
Di Magliano, M.P.2
Heiser, P.W.3
Nielsen, C.M.4
Roberts, D.J.5
Lauwers, G.Y.6
Qi, Y.P.7
Gysin, S.8
Fernandez-Del Castillo, C.9
Yajnik, V.10
Antoniu, B.11
McMahon, M.12
Warshaw, A.L.13
Hebrok, M.14
-
57
-
-
0242268525
-
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
-
DOI 10.1038/nature01972
-
Berman DM, Karhadkar SS, Maitra A, Montes De Oca R, Gerstenblith MR, Briggs K, Parker AR, Shimada Y, Eshleman JR, Watkins DN, Beachy PA. Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours. Nature 425(6960), 846-51. (2003) (Pubitemid 37351469)
-
(2003)
Nature
, vol.425
, Issue.6960
, pp. 846-851
-
-
Berman, D.M.1
Karhadkar, S.S.2
Maitra, A.3
De Oca, R.M.4
Gerstenblith, M.R.5
Briggs, K.6
Parker, A.R.7
Shimada, Y.8
Eshleman, J.R.9
Watkins, D.N.10
Beachy, P.A.11
-
58
-
-
2942616380
-
Indian hedgehog signaling pathway: Expression and regulation in pancreatic cancer
-
DOI 10.1002/ijc.20194
-
Kayed H, Kleeff J, Keleg S, Guo J, Ketterer K, Berberat PO, Giese N, Esposito I, Giese T, Büchler MW, Friess H. Indian hedgehog signaling pathway: expression and regulation in pancreatic cancer. Int J Cancer 110(5), 668-76. (2004) (Pubitemid 38746024)
-
(2004)
International Journal of Cancer
, vol.110
, Issue.5
, pp. 668-676
-
-
Kayed, H.1
Kleeff, J.2
Keleg, S.3
Guo, J.4
Ketterer, K.5
Berberat, P.O.6
Giese, N.7
Esposito, I.8
Giese, T.9
Buchler, M.W.10
Friess, H.11
-
59
-
-
60849118097
-
A direct pancreatic cancer xenograft model as a platform for cancer stem cell therapeutic development
-
Jimeno A, Feldmann G, Suárez-Gauthier A, Rasheed Z, Solomon A, Zou GM, Rubio-Viqueira B, García-García E, López-Ríos F, Matsui W, Maitra A, Hidalgo M. A direct pancreatic cancer xenograft model as a platform for cancer stem cell therapeutic development. Mol Cancer Ther 8(2), 310-4. (2009)
-
(2009)
Mol Cancer Ther
, vol.8
, Issue.2
, pp. 310-314
-
-
Jimeno, A.1
Feldmann, G.2
Suárez-Gauthier, A.3
Rasheed, Z.4
Solomon, A.5
Zou, G.M.6
Rubio-Viqueira, B.7
García-García, E.8
López-Ríos, F.9
Matsui, W.10
Maitra, A.11
Hidalgo, M.12
-
60
-
-
79958229359
-
Cyclopamine reverts acquired chemoresistance and down-regulates cancer stem cell markers in pancreatic cancer cell lines
-
Yao J, An Y, Wie JS, Ji ZL, Lu ZP, Wu JL, Jiang KR, Chen P, Xu ZK, Miao Y. Cyclopamine reverts acquired chemoresistance and down-regulates cancer stem cell markers in pancreatic cancer cell lines. Swiss Med Wkly 141, w13208. (2011)
-
(2011)
Swiss Med Wkly
, vol.141
-
-
Yao, J.1
An, Y.2
Wie, J.S.3
Ji, Z.L.4
Lu, Z.P.5
Wu, J.L.6
Jiang, K.R.7
Chen, P.8
Xu, Z.K.9
Miao, Y.10
-
61
-
-
80755141299
-
Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy
-
Lonardo E, Hermann PC, Mueller MT, Huber S, Balic A, Miranda-Lorenzo I, Zagorac S, Alcala S, Rodriguez- Arabaolaza I, Ramirez JC, Torres-Ruíz R, Garcia E, Hidalgo M, Cebrián DÁ, Heuchel R, Löhr M, Berger F, Bartenstein P, Aicher A, Heeschen C. Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy. Cell Stem Cell 9(5), 433-46. (2011)
-
(2011)
Cell Stem Cell
, vol.9
, Issue.5
, pp. 433-446
-
-
Lonardo, E.1
Hermann, P.C.2
Mueller, M.T.3
Huber, S.4
Balic, A.5
Miranda-Lorenzo, I.6
Zagorac, S.7
Alcala, S.8
Rodriguez-Arabaolaza, I.9
Ramirez, J.C.10
Torres-Ruíz, R.11
Garcia, E.12
Hidalgo, M.13
Cebrián, D.A.14
Heuchel, R.15
Löhr, M.16
Berger, F.17
Bartenstein, P.18
Aicher, A.19
Heeschen, C.20
more..
-
62
-
-
84865635727
-
Sensitization of pancreatic cancer stem cells to gemcitabine by chk1 inhibition
-
Venkatesha VA, Parsels LA, Parsels JD, Zhao L, Zabludoff SD, Simeone DM, Maybaum J, Lawrence TS, Morgan MA. Sensitization of pancreatic cancer stem cells to gemcitabine by chk1 inhibition. Neoplasia 14(6), 519-25. (2012)
-
(2012)
Neoplasia
, vol.14
, Issue.6
, pp. 519-525
-
-
Venkatesha, V.A.1
Parsels, L.A.2
Parsels, J.D.3
Zhao, L.4
Zabludoff, S.D.5
Simeone, D.M.6
Maybaum, J.7
Lawrence, T.S.8
Morgan, M.A.9
|