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Volumn 28, Issue SUPPL 1, 2013, Pages 49-55

Vitamin D in liver diseases: From mechanisms to clinical trials

Author keywords

Alcoholic liver diseases (ALD); Cirrhosis; Fatty liver; Fibrosis; Hepaticsteatosis; Liver diseases; Vitamin D; Vitamin D deficiency.

Indexed keywords

BETA DEFENSIN; CALCITRIOL; CATHELICIDIN; CHOLESTANETRIOL 26 MONOOXYGENASE; CHOLESTEROL 7ALPHA MONOOXYGENASE; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 15; INTERFERON; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 23; INTERLEUKIN 4; INTERLEUKIN 5; RIBAVIRIN; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG; VITAMIN D;

EID: 84880437678     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/jgh.12016     Document Type: Review
Times cited : (49)

References (70)
  • 1
    • 8544284075 scopus 로고    scopus 로고
    • Enzymes involved in the activation and inactivation of vitamin D
    • Prosser DE, Jones G. Enzymes involved in the activation and inactivation of vitamin D. Trends Biochem. Sci. 2004; 29: 664-673.
    • (2004) Trends Biochem. Sci. , vol.29 , pp. 664-673
    • Prosser, D.E.1    Jones, G.2
  • 2
    • 0027245909 scopus 로고
    • Isolation and expression of human 1,25-dihydroxyvitamin D3 24-hydroxylase cDNA
    • Chen KS, Prahl JM, DeLuca HF. Isolation and expression of human 1, 25-dihydroxyvitamin D3 24-hydroxylase cDNA. Proc. Natl Acad. Sci. U.S.A. 1993; 90: 4543-4547.
    • (1993) Proc. Natl Acad. Sci. U.S.A. , vol.90 , pp. 4543-4547
    • Chen, K.S.1    Prahl, J.M.2    DeLuca, H.F.3
  • 3
    • 0021071753 scopus 로고
    • Metabolism of 25-hydroxyvitamin D3 by cultured pulmonary alveolar macrophages in sarcoidosis
    • Adams JS, Sharma OP, Gacad MA, Singer FR. Metabolism of 25-hydroxyvitamin D3 by cultured pulmonary alveolar macrophages in sarcoidosis. J. Clin. Invest. 1983; 72: 1856-1860.
    • (1983) J. Clin. Invest. , vol.72 , pp. 1856-1860
    • Adams, J.S.1    Sharma, O.P.2    Gacad, M.A.3    Singer, F.R.4
  • 4
    • 0023164973 scopus 로고
    • 25-Hydroxyvitamin D3 metabolism by lipopolysaccharide-stimulated normal human macrophages
    • Reichel H, Koeffler HP, Bishop JE, Norman AW. 25-Hydroxyvitamin D3 metabolism by lipopolysaccharide-stimulated normal human macrophages. J. Clin. Endocrinol. Metab. 1987; 64: 1-9.
    • (1987) J. Clin. Endocrinol. Metab. , vol.64 , pp. 1-9
    • Reichel, H.1    Koeffler, H.P.2    Bishop, J.E.3    Norman, A.W.4
  • 5
    • 0026061001 scopus 로고
    • Evidence for 1,25-dihydroxyvitamin D3 production by cultured porcine alveolar macrophages
    • Reichel H, Bishop JE, Koeffler HP, Norman AW. Evidence for 1, 25-dihydroxyvitamin D3 production by cultured porcine alveolar macrophages. Mol. Cell. Endocrinol. 1991; 75: 163-167.
    • (1991) Mol. Cell. Endocrinol. , vol.75 , pp. 163-167
    • Reichel, H.1    Bishop, J.E.2    Koeffler, H.P.3    Norman, A.W.4
  • 6
    • 33748756051 scopus 로고    scopus 로고
    • Immune regulation of 25-hydroxyvitamin D-1alpha-hydroxylase in human monocytic THP1 cells: mechanisms of interferon-gamma-mediated induction
    • Overbergh L, Stoffels K, Waer M, Verstuyf A, Bouillon R, Mathieu C. Immune regulation of 25-hydroxyvitamin D-1alpha-hydroxylase in human monocytic THP1 cells: mechanisms of interferon-gamma-mediated induction. J. Clin. Endocrinol. Metab. 2006; 91: 3566-3574.
    • (2006) J. Clin. Endocrinol. Metab. , vol.91 , pp. 3566-3574
    • Overbergh, L.1    Stoffels, K.2    Waer, M.3    Verstuyf, A.4    Bouillon, R.5    Mathieu, C.6
  • 8
    • 0032907768 scopus 로고    scopus 로고
    • Transcriptional targets of the vitamin D3 receptor-mediating cell cycle arrest and differentiation
    • Freedman LP. Transcriptional targets of the vitamin D3 receptor-mediating cell cycle arrest and differentiation. J. Nutr. 1999; 129: 581S-586.
    • (1999) J. Nutr. , vol.129
    • Freedman, L.P.1
  • 9
    • 0018858224 scopus 로고
    • 25-Hydroxylation of vitamin D3 in liver microsomes and their smooth and rough subfractions
    • Sulimovici S, Roginsky MS, Pfeifer RF. 25-Hydroxylation of vitamin D3 in liver microsomes and their smooth and rough subfractions. Methods Enzymol. 1980; 67: 441-444.
    • (1980) Methods Enzymol. , vol.67 , pp. 441-444
    • Sulimovici, S.1    Roginsky, M.S.2    Pfeifer, R.F.3
  • 10
    • 0035238399 scopus 로고    scopus 로고
    • Enzymatic studies on the key enzymes of vitamin D metabolism; 1 alpha-hydroxylase (CYP27B1) and 24-hydroxylase (CYP24)
    • Inouye K, Sakaki T. Enzymatic studies on the key enzymes of vitamin D metabolism; 1 alpha-hydroxylase (CYP27B1) and 24-hydroxylase (CYP24). Biotechnol. Annu. Rev. 2001; 7: 179-194.
    • (2001) Biotechnol. Annu. Rev. , vol.7 , pp. 179-194
    • Inouye, K.1    Sakaki, T.2
  • 11
    • 0020185344 scopus 로고
    • The vitamin D endocrine system: steroid metabolism, hormone receptors, and biological response (calcium binding proteins)
    • Norman AW, Roth J, Orci L. The vitamin D endocrine system: steroid metabolism, hormone receptors, and biological response (calcium binding proteins). Endocr. Rev. 1982; 3: 331-366.
    • (1982) Endocr. Rev. , vol.3 , pp. 331-366
    • Norman, A.W.1    Roth, J.2    Orci, L.3
  • 12
    • 0037302116 scopus 로고    scopus 로고
    • Intestinal calcium absorption: molecular vitamin D mediated mechanisms
    • Bouillon R, Van Cromphaut S, Carmeliet G. Intestinal calcium absorption: molecular vitamin D mediated mechanisms. J. Cell. Biochem. 2003; 88: 332-339.
    • (2003) J. Cell. Biochem. , vol.88 , pp. 332-339
    • Bouillon, R.1    Van Cromphaut, S.2    Carmeliet, G.3
  • 13
    • 4344665018 scopus 로고    scopus 로고
    • Cutting edge: 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression
    • Wang TT, Nestel FP, Bourdeau V etal. Cutting edge: 1, 25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression. J. Immunol. 2004; 173: 2909-2912.
    • (2004) J. Immunol. , vol.173 , pp. 2909-2912
    • Wang, T.T.1    Nestel, F.P.2    Bourdeau, V.3
  • 14
    • 0022273657 scopus 로고
    • Influence of vitamin D3 metabolites on the production of interleukins 1,2 and 3
    • Hodler B, Evequoz V, Trechsel U, Fleisch H, Stadler B. Influence of vitamin D3 metabolites on the production of interleukins 1, 2 and 3. Immunobiology 1985; 170: 256-269.
    • (1985) Immunobiology , vol.170 , pp. 256-269
    • Hodler, B.1    Evequoz, V.2    Trechsel, U.3    Fleisch, H.4    Stadler, B.5
  • 16
    • 0025868614 scopus 로고
    • Impairment of cytokine production in mice fed a vitamin D3-deficient diet
    • Kankova M, Luini W, Pedrazzoni M etal. Impairment of cytokine production in mice fed a vitamin D3-deficient diet. Immunology 1991; 73: 466-471.
    • (1991) Immunology , vol.73 , pp. 466-471
    • Kankova, M.1    Luini, W.2    Pedrazzoni, M.3
  • 17
    • 42049084378 scopus 로고    scopus 로고
    • Actions and mode of actions of FGF19 subfamily members
    • Fukumoto S. Actions and mode of actions of FGF19 subfamily members. Endocr. J. 2008; 55: 23-31.
    • (2008) Endocr. J. , vol.55 , pp. 23-31
    • Fukumoto, S.1
  • 18
    • 65649152582 scopus 로고    scopus 로고
    • Fibroblast growth factor-19, a novel factor that inhibits hepatic fatty acid synthesis
    • Bhatnagar S, Damron HA, Hillgartner FB. Fibroblast growth factor-19, a novel factor that inhibits hepatic fatty acid synthesis. J. Biol. Chem. 2009; 284: 10023-10033.
    • (2009) J. Biol. Chem. , vol.284 , pp. 10023-10033
    • Bhatnagar, S.1    Damron, H.A.2    Hillgartner, F.B.3
  • 19
    • 0027865604 scopus 로고
    • Nontranscriptional effects of steroid hormones
    • Nemere I, Zhou LX, Norman AW. Nontranscriptional effects of steroid hormones. Receptor 1993; 3: 277-291.
    • (1993) Receptor , vol.3 , pp. 277-291
    • Nemere, I.1    Zhou, L.X.2    Norman, A.W.3
  • 20
    • 0027459349 scopus 로고
    • Generation of inositol phosphates, diacylglycerol and calcium fluxes in myoblasts treated with 1,25-dihydroxyvitamin D3
    • PART 3
    • Morelli S, de Boland AR, Boland RL. Generation of inositol phosphates, diacylglycerol and calcium fluxes in myoblasts treated with 1, 25-dihydroxyvitamin D3. Biochem. J. 1993; 289 (Pt 3): 675-679.
    • (1993) Biochem. J. , vol.289 , pp. 675-679
    • Morelli, S.1    de Boland, A.R.2    Boland, R.L.3
  • 21
    • 0031942938 scopus 로고    scopus 로고
    • Dual 1,25-dihydroxyvitamin D3 signal response pathways in osteoblasts: cross-talk between genomic and membrane-initiated pathways
    • Farach-Carson MC, Ridall AL. Dual 1, 25-dihydroxyvitamin D3 signal response pathways in osteoblasts: cross-talk between genomic and membrane-initiated pathways. Am. J. Kidney Dis. 1998; 31: 729-742.
    • (1998) Am. J. Kidney Dis. , vol.31 , pp. 729-742
    • Farach-Carson, M.C.1    Ridall, A.L.2
  • 22
    • 0018097498 scopus 로고
    • Changes in the kinetics of muscle contraction in vitamin D-depleted rats
    • Rodman JS, Baker T. Changes in the kinetics of muscle contraction in vitamin D-depleted rats. Kidney Int. 1978; 13: 189-193.
    • (1978) Kidney Int. , vol.13 , pp. 189-193
    • Rodman, J.S.1    Baker, T.2
  • 23
    • 33747154772 scopus 로고    scopus 로고
    • Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network
    • Bookout AL, Jeong Y, Downes M, Yu RT, Evans RM, Mangelsdorf DJ. Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network. Cell 2006; 126: 789-799.
    • (2006) Cell , vol.126 , pp. 789-799
    • Bookout, A.L.1    Jeong, Y.2    Downes, M.3    Yu, R.T.4    Evans, R.M.5    Mangelsdorf, D.J.6
  • 25
    • 0022359881 scopus 로고
    • Gamma-Interferon stimulates production of 1,25-dihydroxyvitamin D3 by normal human macrophages
    • Koeffler HP, Reichel H, Bishop JE, Norman AW. Gamma-Interferon stimulates production of 1, 25-dihydroxyvitamin D3 by normal human macrophages. Biochem. Biophys. Res. Commun. 1985; 127: 596-603.
    • (1985) Biochem. Biophys. Res. Commun. , vol.127 , pp. 596-603
    • Koeffler, H.P.1    Reichel, H.2    Bishop, J.E.3    Norman, A.W.4
  • 26
    • 60649109332 scopus 로고    scopus 로고
    • 1Alpha,25-dihydroxyvitamin D3 inhibits CD40L-induced pro-inflammatory and immunomodulatory activity in human monocytes
    • Almerighi C, Sinistro A, Cavazza A, Ciaprini C, Rocchi G, Bergamini A. 1Alpha, 25-dihydroxyvitamin D3 inhibits CD40L-induced pro-inflammatory and immunomodulatory activity in human monocytes. Cytokine 2009; 45: 190-197.
    • (2009) Cytokine , vol.45 , pp. 190-197
    • Almerighi, C.1    Sinistro, A.2    Cavazza, A.3    Ciaprini, C.4    Rocchi, G.5    Bergamini, A.6
  • 27
    • 34247282706 scopus 로고    scopus 로고
    • Vitamin D and the vitamin D receptor are critical for control of the innate immune response to colonic injury
    • Froicu M, Cantorna MT. Vitamin D and the vitamin D receptor are critical for control of the innate immune response to colonic injury. BMC Immunol. 2007; 8: 1-13.
    • (2007) BMC Immunol. , vol.8 , pp. 1-13
    • Froicu, M.1    Cantorna, M.T.2
  • 28
    • 0027291589 scopus 로고
    • 1,25-dihydroxyvitamin D3 production and vitamin D3 receptor expression are developmentally regulated during differentiation of human monocytes into macrophages
    • Kreutz M, Andreesen R, Krause SW, Szabo A, Ritz E, Reichel H. 1, 25-dihydroxyvitamin D3 production and vitamin D3 receptor expression are developmentally regulated during differentiation of human monocytes into macrophages. Blood 1993; 82: 1300-1307.
    • (1993) Blood , vol.82 , pp. 1300-1307
    • Kreutz, M.1    Andreesen, R.2    Krause, S.W.3    Szabo, A.4    Ritz, E.5    Reichel, H.6
  • 29
    • 0023256844 scopus 로고
    • Dendritic cells from human tissues express receptors for the immunoregulatory vitamin D3 metabolite, dihydroxycholecalciferol
    • Brennan A, Katz DR, Nunn JD etal. Dendritic cells from human tissues express receptors for the immunoregulatory vitamin D3 metabolite, dihydroxycholecalciferol. Immunology 1987; 61: 457-461.
    • (1987) Immunology , vol.61 , pp. 457-461
    • Brennan, A.1    Katz, D.R.2    Nunn, J.D.3
  • 30
    • 0034178251 scopus 로고    scopus 로고
    • Vitamin D3 affects differentiation, maturation, and function of human monocyte-derived dendritic cells
    • Piemonti L, Monti P, Sironi M etal. Vitamin D3 affects differentiation, maturation, and function of human monocyte-derived dendritic cells. J. Immunol. 2000; 164: 4443-4451.
    • (2000) J. Immunol. , vol.164 , pp. 4443-4451
    • Piemonti, L.1    Monti, P.2    Sironi, M.3
  • 31
    • 21744438757 scopus 로고    scopus 로고
    • Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1,25-dihydroxyvitamin D3
    • Gombart AF, Borregaard N, Koeffler HP. Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1, 25-dihydroxyvitamin D3. FASEB J. 2005; 19: 1067-1077.
    • (2005) FASEB J. , vol.19 , pp. 1067-1077
    • Gombart, A.F.1    Borregaard, N.2    Koeffler, H.P.3
  • 32
    • 33645224419 scopus 로고    scopus 로고
    • Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response
    • Liu PT, Stenger S, Li H etal. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 2006; 311: 1770-1773.
    • (2006) Science , vol.311 , pp. 1770-1773
    • Liu, P.T.1    Stenger, S.2    Li, H.3
  • 33
    • 67149094732 scopus 로고    scopus 로고
    • Convergence of IL-1beta and VDR activation pathways in human TLR2/1-induced antimicrobial responses
    • Liu PT, Schenk M, Walker VP etal. Convergence of IL-1beta and VDR activation pathways in human TLR2/1-induced antimicrobial responses. PLoS One 2009; 4: e5810.
    • (2009) PLoS One , vol.4
    • Liu, P.T.1    Schenk, M.2    Walker, V.P.3
  • 34
    • 0021678081 scopus 로고
    • Inhibition of T lymphocyte mitogenesis by 1,25-dihydroxyvitamin D3 (calcitriol)
    • Rigby WF, Stacy T, Fanger MW. Inhibition of T lymphocyte mitogenesis by 1, 25-dihydroxyvitamin D3 (calcitriol). J. Clin. Invest. 1984; 74: 1451-1455.
    • (1984) J. Clin. Invest. , vol.74 , pp. 1451-1455
    • Rigby, W.F.1    Stacy, T.2    Fanger, M.W.3
  • 35
    • 0029018309 scopus 로고
    • Immunosuppressive actions of 1,25-dihydroxyvitamin D3: preferential inhibition of Th1 functions
    • Lemire JM, Archer DC, Beck L, Spiegelberg HL. Immunosuppressive actions of 1, 25-dihydroxyvitamin D3: preferential inhibition of Th1 functions. J. Nutr. 1995; 125: 1704S-1708.
    • (1995) J. Nutr. , vol.125
    • Lemire, J.M.1    Archer, D.C.2    Beck, L.3    Spiegelberg, H.L.4
  • 36
    • 0021133183 scopus 로고
    • 1 alpha,25-dihydroxyvitamin D3 suppresses proliferation and immunoglobulin production by normal human peripheral blood mononuclear cells
    • Lemire JM, Adams JS, Sakai R, Jordan SC. 1 alpha, 25-dihydroxyvitamin D3 suppresses proliferation and immunoglobulin production by normal human peripheral blood mononuclear cells. J. Clin. Invest. 1984; 74: 657-661.
    • (1984) J. Clin. Invest. , vol.74 , pp. 657-661
    • Lemire, J.M.1    Adams, J.S.2    Sakai, R.3    Jordan, S.C.4
  • 37
    • 79251595352 scopus 로고    scopus 로고
    • 1alpha,25-dihydroxyvitamin D3 (vitamin D3) catalyzes suppressive activity on human natural regulatory T cells, uniquely modulates cell cycle progression, and augments FOXP3
    • Morales-Tirado V, Wichlan DG, Leimig TE, Street SE, Kasow KA, Riberdy JM. 1alpha, 25-dihydroxyvitamin D3 (vitamin D3) catalyzes suppressive activity on human natural regulatory T cells, uniquely modulates cell cycle progression, and augments FOXP3. Clin. Immunol. 2011; 138: 212-221.
    • (2011) Clin. Immunol. , vol.138 , pp. 212-221
    • Morales-Tirado, V.1    Wichlan, D.G.2    Leimig, T.E.3    Street, S.E.4    Kasow, K.A.5    Riberdy, J.M.6
  • 39
    • 68949140898 scopus 로고    scopus 로고
    • Vitamin D status is positively correlated with regulatory T cell function in patients with multiple sclerosis
    • Smolders J, Thewissen M, Peelen E etal. Vitamin D status is positively correlated with regulatory T cell function in patients with multiple sclerosis. PLoS One 2009; 4: e6635.
    • (2009) PLoS One , vol.4
    • Smolders, J.1    Thewissen, M.2    Peelen, E.3
  • 40
    • 73849123602 scopus 로고    scopus 로고
    • Expansion of antigen-specific regulatory T cells with the topical vitamin D analog calcipotriol
    • Ghoreishi M, Bach P, Obst J, Komba M, Fleet JC, Dutz JP. Expansion of antigen-specific regulatory T cells with the topical vitamin D analog calcipotriol. J. Immunol. 2009; 182: 6071-6078.
    • (2009) J. Immunol. , vol.182 , pp. 6071-6078
    • Ghoreishi, M.1    Bach, P.2    Obst, J.3    Komba, M.4    Fleet, J.C.5    Dutz, J.P.6
  • 41
    • 77950119759 scopus 로고    scopus 로고
    • Vitamin D supplementation and regulatory T cells in apparently healthy subjects: vitamin D treatment for autoimmune diseases?
    • Prietl B, Pilz S, Wolf M etal. Vitamin D supplementation and regulatory T cells in apparently healthy subjects: vitamin D treatment for autoimmune diseases? Isr. Med. Assoc. J. 2010; 12: 136-139.
    • (2010) Isr. Med. Assoc. J. , vol.12 , pp. 136-139
    • Prietl, B.1    Pilz, S.2    Wolf, M.3
  • 42
    • 0035497752 scopus 로고    scopus 로고
    • 1alpha,25-Dihydroxyvitamin d3 has a direct effect on naive CD4(+) T cells to enhance the development of Th2 cells
    • Boonstra A, Barrat FJ, Crain C, Heath VL, Savelkoul HF, O'Garra A. 1alpha, 25-Dihydroxyvitamin d3 has a direct effect on naive CD4(+) T cells to enhance the development of Th2 cells. J. Immunol. 2001; 167: 4974-4980.
    • (2001) J. Immunol. , vol.167 , pp. 4974-4980
    • Boonstra, A.1    Barrat, F.J.2    Crain, C.3    Heath, V.L.4    Savelkoul, H.F.5    O'Garra, A.6
  • 43
    • 4344655342 scopus 로고    scopus 로고
    • Vitamin D receptor-deficient mice fail to develop experimental allergic asthma
    • Wittke A, Weaver V, Mahon BD, August A, Cantorna MT. Vitamin D receptor-deficient mice fail to develop experimental allergic asthma. J. Immunol. 2004; 173: 3432-3436.
    • (2004) J. Immunol. , vol.173 , pp. 3432-3436
    • Wittke, A.1    Weaver, V.2    Mahon, B.D.3    August, A.4    Cantorna, M.T.5
  • 44
    • 77952030839 scopus 로고    scopus 로고
    • 1,25-dihydroxyvitamin D3 enhances the ability of transferred CD4+ CD25+ cells to modulate T helper type 2-driven asthmatic responses
    • Gorman S, Judge MA, Burchell JT, Turner DJ, Hart PH. 1, 25-dihydroxyvitamin D3 enhances the ability of transferred CD4+ CD25+ cells to modulate T helper type 2-driven asthmatic responses. Immunology 2010; 130: 181-192.
    • (2010) Immunology , vol.130 , pp. 181-192
    • Gorman, S.1    Judge, M.A.2    Burchell, J.T.3    Turner, D.J.4    Hart, P.H.5
  • 45
    • 45949104817 scopus 로고    scopus 로고
    • 1alpha,25-dihydroxyvitamin D3 potentiates the beneficial effects of allergen immunotherapy in a mouse model of allergic asthma: role for IL-10 and TGF-beta
    • Taher YA, van Esch BC, Hofman GA, Henricks PA, van Oosterhout AJ. 1alpha, 25-dihydroxyvitamin D3 potentiates the beneficial effects of allergen immunotherapy in a mouse model of allergic asthma: role for IL-10 and TGF-beta. J. Immunol. 2008; 180: 5211-5221.
    • (2008) J. Immunol. , vol.180 , pp. 5211-5221
    • Taher, Y.A.1    van Esch, B.C.2    Hofman, G.A.3    van Henricks, P.A.4    Oosterhout, A.J.5
  • 46
    • 84866382064 scopus 로고    scopus 로고
    • D-livering the message: the importance of vitamin D status in chronic liver disease
    • Kitson MT, Roberts SK. D-livering the message: the importance of vitamin D status in chronic liver disease. J. Hepatol. 2012; 57: 897-909.
    • (2012) J. Hepatol. , vol.57 , pp. 897-909
    • Kitson, M.T.1    Roberts, S.K.2
  • 47
    • 80655127773 scopus 로고    scopus 로고
    • Vitamin D inhibits proliferation and profibrotic marker expression in hepatic stellate cells and decreases thioacetamide-induced liver fibrosis in rats
    • Abramovitch S, Dahan-Bachar L, Sharvit E etal. Vitamin D inhibits proliferation and profibrotic marker expression in hepatic stellate cells and decreases thioacetamide-induced liver fibrosis in rats. Gut 2011; 60: 1728-1737.
    • (2011) Gut , vol.60 , pp. 1728-1737
    • Abramovitch, S.1    Dahan-Bachar, L.2    Sharvit, E.3
  • 48
    • 79960104336 scopus 로고    scopus 로고
    • Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline
    • Holick MF, Binkley NC, Bischoff-Ferrari HA etal. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J. Clin. Endocrinol. Metab. 2011; 96: 1911-1930.
    • (2011) J. Clin. Endocrinol. Metab. , vol.96 , pp. 1911-1930
    • Holick, M.F.1    Binkley, N.C.2    Bischoff-Ferrari, H.A.3
  • 49
    • 58149508302 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease prevalence among school-aged children and adolescents in Iran and its association with biochemical and anthropometric measures
    • Alavian SM, Mohammad-Alizadeh AH, Esna-Ashari F, Ardalan G, Hajarizadeh B. Non-alcoholic fatty liver disease prevalence among school-aged children and adolescents in Iran and its association with biochemical and anthropometric measures. Liver Int. 2009; 29: 159-163.
    • (2009) Liver Int. , vol.29 , pp. 159-163
    • Alavian, S.M.1    Mohammad-Alizadeh, A.H.2    Esna-Ashari, F.3    Ardalan, G.4    Hajarizadeh, B.5
  • 50
    • 38049092013 scopus 로고    scopus 로고
    • Hypovitaminosis D in obese children and adolescents: relationship with adiposity, insulin sensitivity, ethnicity, and season
    • Alemzadeh R, Kichler J, Babar G, Calhoun M. Hypovitaminosis D in obese children and adolescents: relationship with adiposity, insulin sensitivity, ethnicity, and season. Metabolism 2008; 57: 183-191.
    • (2008) Metabolism , vol.57 , pp. 183-191
    • Alemzadeh, R.1    Kichler, J.2    Babar, G.3    Calhoun, M.4
  • 51
    • 2442526414 scopus 로고    scopus 로고
    • Hypovitaminosis D is associated with insulin resistance and beta cell dysfunction
    • Chiu KC, Chu A, Go VL, Saad MF. Hypovitaminosis D is associated with insulin resistance and beta cell dysfunction. Am. J. Clin. Nutr. 2004; 79: 820-825.
    • (2004) Am. J. Clin. Nutr. , vol.79 , pp. 820-825
    • Chiu, K.C.1    Chu, A.2    Go, V.L.3    Saad, M.F.4
  • 53
    • 70349568152 scopus 로고    scopus 로고
    • Relation of body fat indexes to vitamin D status and deficiency among obese adolescents
    • Lenders CM, Feldman HA, Von Scheven E etal. Relation of body fat indexes to vitamin D status and deficiency among obese adolescents. Am. J. Clin. Nutr. 2009; 90: 459-467.
    • (2009) Am. J. Clin. Nutr. , vol.90 , pp. 459-467
    • Lenders, C.M.1    Feldman, H.A.2    Von Scheven, E.3
  • 54
    • 18244382304 scopus 로고    scopus 로고
    • Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
    • Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD, Parks EJ. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J. Clin. Invest. 2005; 115: 1343-1351.
    • (2005) J. Clin. Invest. , vol.115 , pp. 1343-1351
    • Donnelly, K.L.1    Smith, C.I.2    Schwarzenberg, S.J.3    Jessurun, J.4    Boldt, M.D.5    Parks, E.J.6
  • 55
    • 84863427742 scopus 로고    scopus 로고
    • Non-alcoholic Fatty liver disease: the bile Acid-activated farnesoid x receptor as an emerging treatment target
    • Fuchs M. Non-alcoholic Fatty liver disease: the bile Acid-activated farnesoid x receptor as an emerging treatment target. J Lipids. 2012; 2012: 934396.
    • (2012) J Lipids. , vol.2012 , pp. 934396
    • Fuchs, M.1
  • 56
    • 33745122240 scopus 로고    scopus 로고
    • Transactivation of rat apical sodium-dependent bile acid transporter and increased bile acid transport by 1alpha,25-dihydroxyvitamin D3 via the vitamin D receptor
    • Chen X, Chen F, Liu S etal. Transactivation of rat apical sodium-dependent bile acid transporter and increased bile acid transport by 1alpha, 25-dihydroxyvitamin D3 via the vitamin D receptor. Mol. Pharmacol. 2006; 69: 1913-1923.
    • (2006) Mol. Pharmacol. , vol.69 , pp. 1913-1923
    • Chen, X.1    Chen, F.2    Liu, S.3
  • 57
    • 0035206829 scopus 로고    scopus 로고
    • Transcriptional control of intestinal cytochrome P-4503A by 1alpha,25-dihydroxy vitamin D3
    • Thummel KE, Brimer C, Yasuda K etal. Transcriptional control of intestinal cytochrome P-4503A by 1alpha, 25-dihydroxy vitamin D3. Mol. Pharmacol. 2001; 60: 1399-1406.
    • (2001) Mol. Pharmacol. , vol.60 , pp. 1399-1406
    • Thummel, K.E.1    Brimer, C.2    Yasuda, K.3
  • 58
    • 0037067665 scopus 로고    scopus 로고
    • Expression of CYP3A4, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human hepatocytes
    • Drocourt L, Ourlin JC, Pascussi JM, Maurel P, Vilarem MJ. Expression of CYP3A4, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human hepatocytes. J. Biol. Chem. 2002; 277: 25125-25132.
    • (2002) J. Biol. Chem. , vol.277 , pp. 25125-25132
    • Drocourt, L.1    Ourlin, J.C.2    Pascussi, J.M.3    Maurel, P.4    Vilarem, M.J.5
  • 59
    • 79955931061 scopus 로고    scopus 로고
    • Vitamin D deficiency in cirrhosis relates to liver dysfunction rather than aetiology
    • Malham M, Jorgensen SP, Ott P etal. Vitamin D deficiency in cirrhosis relates to liver dysfunction rather than aetiology. World J. Gastroenterol. 2011; 17: 922-925.
    • (2011) World J. Gastroenterol. , vol.17 , pp. 922-925
    • Malham, M.1    Jorgensen, S.P.2    Ott, P.3
  • 60
    • 84871189038 scopus 로고    scopus 로고
    • Vitamin D for your patients with chronic hepatitis C?
    • Rahman AH, Branch AD. Vitamin D for your patients with chronic hepatitis C? J. Hepatol. 2013; 58: 184-189.
    • (2013) J. Hepatol. , vol.58 , pp. 184-189
    • Rahman, A.H.1    Branch, A.D.2
  • 61
    • 77950624679 scopus 로고    scopus 로고
    • Low vitamin D serum level is related to severe fibrosis and low responsiveness to interferon-based therapy in genotype 1 chronic hepatitis C
    • Petta S, Camma C, Scazzone C etal. Low vitamin D serum level is related to severe fibrosis and low responsiveness to interferon-based therapy in genotype 1 chronic hepatitis C. Hepatology 2010; 51: 1158-1167.
    • (2010) Hepatology , vol.51 , pp. 1158-1167
    • Petta, S.1    Camma, C.2    Scazzone, C.3
  • 62
    • 83755196636 scopus 로고    scopus 로고
    • Vitamin D supplementation improves sustained virologic response in chronic hepatitis C (genotype 1)-naive patients
    • Abu-Mouch S, Fireman Z, Jarchovsky J, Zeina AR, Assy N. Vitamin D supplementation improves sustained virologic response in chronic hepatitis C (genotype 1)-naive patients. World J. Gastroenterol. 2011; 17: 5184-5190.
    • (2011) World J. Gastroenterol. , vol.17 , pp. 5184-5190
    • Abu-Mouch, S.1    Fireman, Z.2    Jarchovsky, J.3    Zeina, A.R.4    Assy, N.5
  • 63
    • 84857532001 scopus 로고    scopus 로고
    • Vitamin D improves viral response in hepatitis C genotype 2-3 naive patients
    • Nimer A, Mouch A. Vitamin D improves viral response in hepatitis C genotype 2-3 naive patients. World J. Gastroenterol. 2012; 18: 800-805.
    • (2012) World J. Gastroenterol. , vol.18 , pp. 800-805
    • Nimer, A.1    Mouch, A.2
  • 64
    • 84864484324 scopus 로고    scopus 로고
    • Vitamin D deficiency: correlation to interleukin-17, interleukin-23 and PIIINP in hepatitis C virus genotype 4
    • Schaalan MF, Mohamed WA, Amin HH. Vitamin D deficiency: correlation to interleukin-17, interleukin-23 and PIIINP in hepatitis C virus genotype 4. World J. Gastroenterol. 2012; 18: 3738-3744.
    • (2012) World J. Gastroenterol. , vol.18 , pp. 3738-3744
    • Schaalan, M.F.1    Mohamed, W.A.2    Amin, H.H.3
  • 65
    • 80055060055 scopus 로고    scopus 로고
    • Vitamin D: an innate antiviral agent suppressing hepatitis C virus in human hepatocytes
    • Gal-Tanamy M, Bachmetov L, Ravid A etal. Vitamin D: an innate antiviral agent suppressing hepatitis C virus in human hepatocytes. Hepatology 2011; 54: 1570-1579.
    • (2011) Hepatology , vol.54 , pp. 1570-1579
    • Gal-Tanamy, M.1    Bachmetov, L.2    Ravid, A.3
  • 66
    • 84867162487 scopus 로고    scopus 로고
    • 25-hydroxyvitamin D(3) suppresses hepatitis C virus production
    • Matsumura T, Kato T, Sugiyama N etal. 25-hydroxyvitamin D(3) suppresses hepatitis C virus production. Hepatology 2012; 56: 1231-1239.
    • (2012) Hepatology , vol.56 , pp. 1231-1239
    • Matsumura, T.1    Kato, T.2    Sugiyama, N.3
  • 67
    • 84868193472 scopus 로고    scopus 로고
    • Vitamin D binding protein gene polymorphisms and baseline vitamin D levels as predictors of antiviral response in chronic hepatitis C
    • Falleti E, Bitetto D, Fabris C etal. Vitamin D binding protein gene polymorphisms and baseline vitamin D levels as predictors of antiviral response in chronic hepatitis C. Hepatology 2012; 56: 1641-1650.
    • (2012) Hepatology , vol.56 , pp. 1641-1650
    • Falleti, E.1    Bitetto, D.2    Fabris, C.3
  • 68
    • 67349255018 scopus 로고    scopus 로고
    • Vitamin D receptor polymorphisms are associated with increased susceptibility to primary biliary cirrhosis in Japanese and Italian populations
    • Tanaka A, Nezu S, Uegaki S etal. Vitamin D receptor polymorphisms are associated with increased susceptibility to primary biliary cirrhosis in Japanese and Italian populations. J. Hepatol. 2009; 50: 1202-1209.
    • (2009) J. Hepatol. , vol.50 , pp. 1202-1209
    • Tanaka, A.1    Nezu, S.2    Uegaki, S.3
  • 69
    • 14844331387 scopus 로고    scopus 로고
    • Genetic association of vitamin D receptor polymorphisms with autoimmune hepatitis and primary biliary cirrhosis in the Chinese
    • Fan L, Tu X, Zhu Y etal. Genetic association of vitamin D receptor polymorphisms with autoimmune hepatitis and primary biliary cirrhosis in the Chinese. J. Gastroenterol. Hepatol. 2005; 20: 249-255.
    • (2005) J. Gastroenterol. Hepatol. , vol.20 , pp. 249-255
    • Fan, L.1    Tu, X.2    Zhu, Y.3
  • 70
    • 84858281844 scopus 로고    scopus 로고
    • Combined effect of 25-OH vitamin D plasma levels and genetic vitamin D receptor (NR 1I1) variants on fibrosis progression rate in HCV patients
    • Baur K, Mertens JC, Schmitt J etal. Combined effect of 25-OH vitamin D plasma levels and genetic vitamin D receptor (NR 1I1) variants on fibrosis progression rate in HCV patients. Liver Int. 2012; 32: 635-643.
    • (2012) Liver Int. , vol.32 , pp. 635-643
    • Baur, K.1    Mertens, J.C.2    Schmitt, J.3


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