A Single Amino Acid Substitution in the Core Protein of West Nile Virus Increases Resistance to Acidotropic Compounds

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Martín Acebes, Miguel A ^a,c   Blázquez, Ana Belén ^a   de Oya, Nereida Jiménez ^a,d   Escribano Romero, Estela ^a   Shi, Pei Yong ^b,e   Saiz, Juan Carlos ^a  

^a INIA   (Spain)

^b WADSWORTH CENTER   (United States)

^c CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

^d SAN RAFFAELE HOSPITAL   (Italy)

^e NOVARTIS INSTITUTE FOR TROPICAL DISEASES   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; AMMONIUM CHLORIDE; CONCANAMYCIN A; CORE PROTEIN; GLUTAMINE; LYSINE; VIRUS PROTEIN;

ACIDIFICATION; AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENDOSOME; FEMALE; GENETIC STABILITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PH; PHENOTYPE; TRANS GOLGI NETWORK; VIRION; VIRUS ENTRY; VIRUS ENVELOPE; WEST NILE FLAVIVIRUS;

AMINO ACID SUBSTITUTION; AMMONIUM CHLORIDE; ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; CERCOPITHECUS AETHIOPS; CRICETINAE; DRUG RESISTANCE, VIRAL; FLUORESCENT ANTIBODY TECHNIQUE; HYDROGEN-ION CONCENTRATION; MACROLIDES; MICE; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; VERO CELLS; VIRAL CORE PROTEINS; VIRULENCE; WEST NILE VIRUS;

EID: 84880419982     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0069479     Document Type: Article

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