Acid-induced movements in the glycoprotein shell of an alphavirus turn the spikes into membrane fusion mode

EMBO Journal

Volumn 21, Issue 17, 2002, Pages 4402-4410

  Haag, Lars ^a   Garoff, Henrik ^a   Xing, Li ^a   Hammar, Lena ^a   Kan, Sin Tau ^a,b   Cheng, R Holland ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Pharmacia   (Sweden)

Author keywords

Alphavirus; Cryo EM; Glycoprotein; Image reconstruction; Membrane fusion

Indexed keywords

GLYCOPROTEIN; VIRUS ENVELOPE PROTEIN; VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; CRYOELECTRON MICROSCOPY; IMAGE RECONSTRUCTION; LIPID BILAYER; MEMBRANE FUSION; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN INTERACTION; SEMLIKI FOREST ALPHAVIRUS;

ALKANESULFONIC ACIDS; ANIMALS; CAPSID; CELL LINE; CRICETINAE; CRYOELECTRON MICROSCOPY; CYTOPATHOGENIC EFFECT, VIRAL; DIMERIZATION; ENDOSOMES; HYDROGEN-ION CONCENTRATION; IMAGE PROCESSING, COMPUTER-ASSISTED; KIDNEY; LIPID BILAYERS; MEMBRANE FUSION; MESOCRICETUS; MORPHOLINES; PROTEIN STRUCTURE, TERTIARY; SEMLIKI FOREST VIRUS; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL FUSION PROTEINS;

ALPHAVIRUS; ANIMALIA; ENTEROBACTERIA PHAGE T4; RNA VIRUSES; SEMLIKI FOREST VIRUS;

EID: 0037009367     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdf442     Document Type: Article

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