The small GTPase HRas shapes local PI3K signals through positive feedback and regulates persistent membrane extension in migrating fibroblasts

Molecular Biology of the Cell

Volumn 24, Issue 14, 2013, Pages 2228-2237

  Thevathasan, Jervis Vermal ^a   Tan, Elisabeth ^a   Zheng, Hui ^a   Lin, Yu Chun ^b   Li, Yang ^a   Inoue, Takanari ^b   Fivaz, Marc ^a,c  

^a DUKE NUS MEDICAL SCHOOL   (Singapore)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

FK 506 BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE LYN; RAS PROTEIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; FIBROBLAST; MOUSE; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; SIGNAL TRANSDUCTION;

ANIMALS; CELL MEMBRANE; CELL MOVEMENT; FEEDBACK, PHYSIOLOGICAL; GENE EXPRESSION REGULATION; MICE; NIH 3T3 CELLS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHATIDYLINOSITOLS; PLATELET-DERIVED GROWTH FACTOR; PROTO-ONCOGENE PROTEINS P21(RAS); RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TIME-LAPSE IMAGING;

EID: 84880401483     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E12-12-0905     Document Type: Article

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