Sulphur antioxidants inhibit oxidative stress induced retinal ganglion cell death by scavenging reactive oxygen species but influence nuclear factor (erythroid-derived 2)-like 2 signalling pathway differently

Biological and Pharmaceutical Bulletin

Volumn 36, Issue 7, 2013, Pages 1095-1110

  Majid, Aman Shah Abdul ^a,b   Yin, Zheng Qin ^c   Ji, Dan ^a,c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b ADVANCED MEDICAL AND DENTAL INSTITUTE   (Malaysia)

^c THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Oxidative stress; Reactive oxygen species; Retinal ganglion cell; Sulphur antioxidant

Indexed keywords

ACETYLCYSTEINE; BENZOYLCARBONYL VALYLALANYLASPARTIC ACID FLUORO METHYL KETONE; CASPASE 3; CATALASE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HEME OXYGENASE 1; MESSENGER RNA; NECROSTATIN 1; NEUROPROTECTIVE AGENT; NUCLEAR FACTOR (ERYTHROID DERIVED 2) LIKE 2 PROTEIN; REACTIVE OXYGEN METABOLITE; SULBUTIAMINE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL ASSAY; CELL DEATH; CELL SURVIVAL; CELL TRANSFORMATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME SYNTHESIS; IN VITRO STUDY; INTRACELLULAR SIGNALING; NECROPTOSIS; NERVE CELL CULTURE; NEUROPROTECTION; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; RETINA GANGLION CELL; WESTERN BLOTTING;

ACETYLCYSTEINE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL CULTURE TECHNIQUES; CELL LINE, TRANSFORMED; CELL SURVIVAL; FREE RADICAL SCAVENGERS; HEME OXYGENASE (DECYCLIZING); NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; RATS; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; RETINAL GANGLION CELLS; SIGNAL TRANSDUCTION; THIAMINE;

EID: 84880397673     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b13-00023     Document Type: Article

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